Hnub no muaj kev nce ntxiv ntawm cov kab mob kis tau zoo ntawm qhov xwm txheej, uas yog tshwm sim los ntawm kev nce qib ntawm kev cuam tshuam ntawm ib puag ncig tsis zoo rau tib neeg lub cev. Thawj qhov chaw ntawm cov kab mob fungal ntawm lub plab zom mov yog thrush, thaum nyob rau hauv 80% ntawm cov neeg mob plab hnyuv candidiasis. Tus kab mob no provoked los ntawm fungi Candida albicans.
Feem ntau, kwv yees li ib nrab ntawm cov neeg nyob hauv ntiaj teb niaj hnub no yog cov kab mob fungi, lawv nyob hauv lub xeev tsis muaj zog hauv lub cev, tab sis thaum lub cev tsis muaj zog, lawv ua kom nquag plias thiab pib loj hlob sai. qhov ntau. Tus kab mob ua rau kev txhim kho cov txheej txheem pathological hauv txoj hnyuv, cuam tshuam rau nws cov mucous membrane.
Problem description
plab hnyuv candidiasis yog ib yam kab mob sib kis uas cuam tshuam rau cov mucous daim nyias nyias ntawm lub cev. Cov kab mob ua rau cov kab mob pathology, raws li twb tau hais lawm, yog Candida albicans fungi uas nkag mus rau hauv lub cev thiab ua kom nquag plias vim tib neeg lub cev tsis muaj zog. Ib txwm pathogenic microflorayog ib qho tseem ceeb ntawm kev sib npaug ntawm lub qhov ncauj kab noj hniav, lub plab zom mov thiab lub plab zom mov, kev ua me nyuam, tsis ua rau kev loj hlob ntawm tus kab mob. Tab sis nyob rau hauv kev cuam tshuam ntawm qee yam tsis zoo, kev loj hlob sai ntawm cov fungi pib, uas hloov cov microflora ib txwm thiab provoke kev loj hlob ntawm candidiasis (thrush)..
Cov kws kho mob xa cov plab hnyuv candidiasis rau ib qho ntawm ntau yam ntawm dysbacteriosis. Nceb txuas mus rau lub epithelium, tom qab ntawd kis tau ib daim ntawv filamentous thiab nkag mus rau hauv cov ntaub so ntswg, provoking cov tsos ntawm necrotic cheeb tsam nyob rau hauv lub foci ntawm o. Nyob ib ncig ntawm cov chaw no, fibrin protein pib tso. Lub plab microflora noj qab nyob zoo tsim cov tshuaj tiv thaiv kab mob, uas ua kom muaj kev tiv thaiv kab mob txaus. Tab sis yog tias microflora cuam tshuam los ntawm kev txo qis hauv kev tiv thaiv, cov kab mob pib kis mus rau thaj chaw noj qab haus huv tshiab.
Kab mob kis
Candida nceb muaj ntau heev nyob rau hauv xwm. Thiab tus kab mob tau piav qhia tuaj yeem kuaj tau hauv cov neeg ntawm ntau pawg hnub nyoog, poj niam txiv neej thiab haiv neeg. Thrush tuaj yeem txhim kho nyob rau hauv kev cuam tshuam ntawm ntau yam laj thawj:
- raws li cov kev mob tshwm sim ntawm kev siv mus sij hawm ntev ntawm cov tshuaj tua kab mob dav dav;
- vim vim noj tshuaj corticosteroids lossis tshuaj hormones;
- yog ib qho teeb meem ntawm ntshav qab zib thiab kab mob endocrine;
- nrog kev tiv thaiv kab mob;
- nyob rau hauv lub xub ntiag ntawm cov kab mob sib kis ntawm tus kab mob.
Cas of disease development
Raws li koj paub, vim li casTxoj kev loj hlob ntawm pathology yog ua si los ntawm fungi Candida albicans, uas tam sim no nyob rau hauv lub cev noj qab haus huv thiab pib sib npaug thaum nws cov khoom tiv thaiv tsis muaj zog. Cov laj thawj rau qhov txo qis hauv kev tiv thaiv muaj xws li:
- Oncological pathologies, kws khomob.
- Immunodeficiency uas tshwm sim los ntawm kev hloov pauv ntawm hnub nyoog, kev ntxhov siab, cev xeeb tub, thiab muaj HIV lossis AIDS.
- Endocrine Disorder.
- Autoimmune thiab allergic pathologies.
- Kab mob ntawm lub plab zom mov.
- Kev hloov pauv ntawm tus neeg pub khoom nruab nrog cev thiab cov ntaub so ntswg.
- Kev siv tshuaj tua kab mob thiab tshuaj hormonal ntev.
- Kev ua txhaum cai ntawm hnub thiab khoom noj khoom haus.
- Nyob rau hauv ib puag ncig kev ua phem.
Mechanisms of disease progression
Hauv tshuaj, nws yog ib txwm ua kom paub qhov txawv ntawm ob lub tswv yim rau kev txhim kho candidiasis:
- Tus kab mob thrush yog tus cwj pwm los ntawm kev nkag mus ntawm cov kab mob mus rau hauv cov hnyuv epithelial cov ntaub so ntswg. Tawm tsam keeb kwm yav dhau los ntawm kev txo qis hauv kev tiv thaiv, fungi nkag mus rau hauv cov hlab ntsha thiab kis thoob plaws lub cev. Qhov tshwm sim no feem ntau pom nyob rau hauv cov neeg uas muaj theem kawg ntawm AIDS, nrog rau neutropenia. Hom kab mob no muaj ob hom subspecies: focal thiab diffuse candidiasis.
- Tsis yog-tus kab mob thrush yog feem ntau. Tus kab mob manifests nws tus kheej tawm tsam keeb kwm ntawm dysbacteriosis lossis kab mob hauv plab. Thaum lub sij hawm yug me nyuam ntawm fungi, co toxins raug tsim tawm uas irritate tib neeg txoj hnyuv, pab txhawb rau exacerbation ntawm dysbacteriosis, kev loj hlob.kev tsis haum tshuaj thiab kev tiv thaiv kab mob thib ob.
txhawm rau txo qhov kev pheej hmoo ntawm cov teeb meem, nws raug nquahu kom kuaj xyuas thiab kho tus kabmob raws sijhawm. Txhawm rau txhim kho txoj kev kho kom zoo, tus kws kho mob yuav tsum paub qhov ua rau ntawm pathology.
Symptoms and signs of disease
Tus kab mob muaj peb theem ntawm kev loj hlob:
- Lub sijhawm tsis txaus ntseeg uas tsis muaj cov tsos mob tshwm sim.
- Ntaus febrile syndrome nrog cov tsos mob ntawm tus kab mob.
- Visceralization, uas cov tsos mob ntawm ntau yam kab mob tshwm sim.
Cov tsos mob ntawm plab hnyuv candidiasis feem ntau tshwm sim qeeb rau lub sijhawm ntev, tab sis qee zaum qhov mob hnyav ntawm nws nrog cov tsos mob tshwm sim tau.
Cov tsos mob ntawm ntau hom kab mob muaj xws li:
- poob qab los;
- faus;
- flatulence;
- mob thiab tsis xis nyob hauv plab;
- qhov quav khaus;
- mob me me ntawm lub cev;
- Cov quav tsis huv thaum lub plab zom mov.
Cov tsos mob ntawm kev loj hlob ntawm ntau hom kab mob candidiasis
Nrog diffuse thrush, tus neeg mob tus mob feem ntau hnyav heev, vim yog intoxication ntawm lub cev. Nyob rau hauv cov ntaub ntawv no, cov tsos mob ntawm plab hnyuv candidiasis yog tshwm sim nyob rau hauv daim ntawv ntawm mob hnyav nyob rau hauv lub plab mog, raws plab, nrog rau cov ntshav tawm, raws li zoo raws li ib tug muaj zog nce nyob rau hauv lub cev kub. Daim ntawv no ntawm pathology yog ib txwm nrog los ntawm kev ua txhaum loj.tiv thaiv kab mob, yog li nws feem ntau nrog lwm yam kab mob.
Thaum focal thrush nyob rau hauv tib neeg exacerbates cov kab mob xws li plab los yog duodenal ulcers, ulcerative colitis, uas yog amenable rau standard kho. Cov tsos mob ntawm tib yam pathology sib raug rau cov kab mob hauv qab.
Tab sis feem ntau muaj kev tshuaj xyuas ntawm plab hnyuv candidiasis, uas tsis yog-invasive. Nrog kev pab los ntawm cov tshuaj niaj hnub, nws muaj peev xwm tshem tawm tag nrho cov kab mob no. Nrog nws, ib tug neeg muaj mob nyob rau hauv lub plab mog, flatulence, indigestion, tsis xis nyob. Qee zaum kev ua xua tuaj yeem tshwm sim.
Ntau zaus, cov kws kho mob cuam tshuam candidiasis nrog lub plab zom mov, vim tias cov tsos mob ntawm ob kab mob no zoo sib xws.
Cov Teeb Meem thiab qhov tshwm sim
Nrog kev kho tsis tu ncua lossis nws tsis tuaj, nrog rau kev kho tus kheej ntawm tus kab mob, nws dhau los ua mob ntev, uas cov kab mob nkag mus tob rau hauv cov ntaub so ntswg, rhuav tshem lawv cov qauv. Nyob rau hauv lub neej yav tom ntej, lub pathology provokes txoj kev loj hlob ntawm cov teeb meem nyob rau hauv daim ntawv ntawm cov hnyuv ulcers, kev loj hlob ntawm lub sab hauv los ntshav thiab sepsis. Cov xwm txheej zoo li no ua rau muaj kev phom sij rau txoj sia vim lawv tuaj yeem ua rau tuag taus.
Raws li muaj teeb meem, raws plab ntev zuj zus, uas ua rau lub cev qhuav dej. Thaum cev xeeb tub, pathology tuaj yeem ua rau fetus tuag lossis nchuav menyuam.
ntsuas ntsuas
plab hnyuv candidiasis muaj qee qhov teeb meem hauv kev kuaj mob, txij li tus neeg sawv cev ntawm tus kab mob tuaj yeemTsis txhob koom nrog hauv cov txheej txheem pathological, nyob hauv lub cev hauv lub xeev passive. Hauv qhov no, tus kws kho mob ua qhov kev kuaj mob los ntawm kev cais tawm. Rau qhov no, kev kuaj mob thiab kev kuaj mob nyuaj yog siv:
- Kev tshuaj xyuas microbiological ntawm cov quav kom pom muaj tus kab mob sib kis. Txoj kev no kuj tso cai rau koj xaiv cov tshuaj tua kab mob uas cov fungi rhiab tshaj plaws.
- Kev kuaj endoscopic ua rau nws muaj peev xwm txiav txim siab txog qhov mob ntawm txoj hnyuv epithelium, txhawm rau txheeb xyuas qhov mob thiab cov quav hniav dawb.
- Histological thiab cytological kev tshawb fawb ntawm scrapings los ntawm txoj hnyuv epithelium, nrog rau forceps biopsy. Hauv qhov no, txoj kev Romanovsky-Giemsa yog siv, nrog rau txoj kev Gridley.
- x-ray plab hnyuv.
- kab lis kev cai ntawm cov khoom siv los ntawm cov hnyuv mucosa.
- PCR thiab ELISA.
Ua ntej kho cov hnyuv candidiasis, tus kws kho mob yuav tsum ua kom tiav kev kuaj mob thiab kuaj xyuas kom raug. Qhov nyuaj ntawm kev kuaj mob pathology nyob rau hauv qhov tseeb tias cov kab mob tsis tuaj yeem pom hauv txhua yam ntaub ntawv uas tau tshuaj xyuas. Yog li ntawd, feem ntau cov qhabnias xeem yog cuav. Txhua tus neeg mob yuav tsum tau mus kuaj mob dysbacteriosis.
Nrog kev kho tus kab mob tsis tu ncua, nws degenerates rau hauv cov kab mob thrush, uas tag nrho cov mucous daim nyias nyias ntawm lub cev raug cuam tshuam.
Txoj Kev Kho Mob
Kev kho mob plab hnyuv candidiasis yog tsom rau kev tshem tawm cov kab mob sib kis, ua kom muaj kev tiv thaiv kab mob thiabtshem tawm ntawm tus kab mob. Cov kev xaiv ntawm kev kho mob tactics nyob ntawm seb cov tsos mob ntawm tus kab mob, lub xub ntiag ntawm pathologies ntawm lub digestive ib ntsuj av, kev loj hlob ntawm cov teeb meem, raws li zoo raws li cov kev mob ntawm tus neeg mob.
Feem ntau, kev kho mob plab hnyuv candidiasis yog siv cov tshuaj antimycotic, uas tuaj yeem muab tshuaj hauv cov ntsiav tshuaj lossis txhaj tshuaj. Feem ntau, nrog rau cov tshuaj no, tus neeg mob tau muab tshuaj tua kab mob uas tsim nyog los txo qis kev pheej hmoo ntawm kev kis kab mob thib ob. Thiab yuav luag txhua tus neeg mob tau muab tshuaj immunostimulants, nrog rau cov tshuaj tiv thaiv kab mob.
Drug therapy
Tshuaj siv rau plab hnyuv candidiasis yog cais raws li hauv qab no:
- Antimycotics tshem tawm cov kab mob ua rau tus kab mob.
- Antibacterial - tshem tawm cov kab mob thib ob.
- Tshuaj rau cov tsos mob ntawm cov kab mob sib kis.
- Probiotics siv los kho cov hnyuv microflora.
Nws yuav tsum tau muab sau tseg tias "Amphotericin", "Ketoconazole" thiab "Fluconazole" tsis muab cov txiaj ntsig zoo hauv plab hnyuv candidiasis, vim tias lawv tsuas yog nqus los ntawm txoj hnyuv sab sauv xwb, vim tias qhov xav tau ntawm cov tshuaj. tsis ncav cuag lub lumen ntawm txoj hnyuv, qhov twg qhov loj tshaj plaws concentration ntawm fungi yog feem ntau pom. Los ntawm txoj kev, nyob rau hauv cov ntaub ntawv no, kev loj hlob ntawm kev phiv nyob rau hauv daim ntawv ntawm tshuaj lom kab mob siab yog txawm ua tau.
Rau cov menyuam yaus thiab cov poj niam cev xeeb tub, kws kho mob feem ntauTshuaj "Pimafucin" rau plab hnyuv candidiasis. Cov tshuaj no tsis ua rau muaj kev cuam tshuam tsis zoo thiab suav tias yog kev kho mob zoo rau cov kab mob no. Nws yog noj ib ntsiav tshuaj plaub zaug ib hnub twg rau ib lub lis piam. Cov me nyuam raug muab ob ntsiav tshuaj ib hnub.
Ua ke nrog kev tshem tawm cov kab mob, raws li tau hais lawm, kev kho mob sib kis tau ua tiav. Rau qhov no, tshuaj antisecretory, vitamins, H2-receptor blockers thiab lwm yam tuaj yeem raug sau.
Kev noj zaub mov rau plab hnyuv candidiasis
Thaum kho tus mob candidiasis, cov neeg mob yuav tsum ua raws li kev noj zaub mov tshwj xeeb. Yog li, los ntawm kev noj zaub mov txhua hnub nws yog ib qho tsim nyog yuav tsum tshem tawm tag nrho cov khoom noj uas tuaj yeem ua rau muaj cov kab mob fungal, piv txwv li, zib ntab, txiv hmab txiv ntoo qab zib, cawv, dej qab zib carbonated, nceb. Koj tsis tuaj yeem noj cov zaub mov muaj rog, haus luam yeeb thiab hmoov nplej. Lub hauv paus ntawm kev noj haus nyob rau hauv cov ntaub ntawv no yuav tsum yog noj zaub uas tsis muaj cov ntsiab lus ntawm cov hmoov txhuv nplej siab thiab qaub-mis, nrog rau cov khoom uas muaj cov carbohydrates yooj yim.
Huab cua
Nrog kev kuaj mob raws sij hawm thiab kev kho mob, tus neeg tau txais kev rov zoo tag nrho. Nyob rau hauv cov ntaub ntawv ntawm kev loj hlob ntawm ib tug diffuse daim ntawv ntawm pathology, cov teeb meem yuav tshwm sim nyob rau hauv daim ntawv ntawm kev sib kis ntawm ib tug txawv txav txheej txheem thoob plaws hauv lub cev. Nyob rau hauv lub xub ntiag ntawm ib tug kab mob nyob rau hauv lub hauv paus, qhov prognosis tej zaum yuav tsis zoo. Yog tias tsis kho, tus kab mob yuav mob ntev thiab tuaj yeem ua rau tuag taus vim muaj tus kab mob sepsis.
Kev Tiv Thaiv
ntsuas kev tiv thaivyog qhov tseem ceeb heev. Nyob rau hauv rooj plaub no, lawv yuav tsum tau tsom mus rau kev tshem tawm cov kev pheej hmoo, nrog rau kev kho mob raws sij hawm ntawm cov kab mob uas ua rau plab hnyuv dysbacteriosis. Txhawm rau tswj cov microflora ntawm cov mucous daim nyias nyias, nws raug nquahu kom noj txoj cai, ua kom muaj fiber ntau, saib xyuas tus kheej kev nyiam huv thiab ua lub neej noj qab haus huv. Thaum kho nrog tshuaj tua kab mob lossis tshuaj hormonal, probiotics yuav tsum tau siv los tiv thaiv dysbacteriosis thiab candidiasis.
Candidiasis lossis thrush yog ib yam kab mob nyuaj uas xav tau kev kuaj mob thiab kho raws sijhawm. Yog tias koj muaj kev tsis xis nyob hauv plab, mob thiab khaus, koj yuav tsum sab laj nrog kws kho mob tam sim ntawd kom txo qis kev pheej hmoo ntawm kev tsim teeb meem txaus ntshai.
