Mycophenolate mofetil (INN Mycophenolic acid) belongs rau pab pawg ntawm cov tshuaj tiv thaiv kab mob. Cia peb xav txog ntau yam nyob rau hauv cov ntaub ntawv twg nws yog tsim nyog los siv cov tshuaj, dab tsi yog contraindications rau nws siv thiab phiv.
Dhau li ntawm no, peb yuav pom tias muaj cov tshuaj zoo sib xws hauv cov tshuaj niaj hnub no.
Cov ntaub ntawv tseem ceeb
Mycophenolate mofetil muaj nyob rau hauv cov kaus ntxhw tawv gelatin capsule nrog cov hmoov dawb sab hauv.
Koj tuaj yeem yuav tshuaj hauv lub tsev muag tshuaj tsuas yog nrog daim ntawv xaj los ntawm kws kho mob.
Lub neej txee ntawm cov khoom yog ob xyoos. Nws yuav tsum tau khaws cia ntawm qhov kub txog li 25 degrees.
Yuav kom muaj kev nkag siab pom ntawm yam tshuaj uas peb tab tom xav txog (mycophenolate mofetil) zoo li, daim duab saum toj no yuav ua piv txwv zoo.
Cov tshuaj
Ib ntsiav tshuaj ntawm cov khoom muaj 250 mg ntawm cov tshuaj nquag (mycophenolate mofetil). Tsis tas li ntawd, kuj tseem muaj cov khoom pabcuam, xws li croscarmellose sodium, microcrystalline cellulose,magnesium stearate thiab povidone.
YPharmacokinetics
Tom qab siv cov tshuaj, nws tau nqus tag nrho thiab ua tiav cov metabolism hauv presystemic. Nyob rau tib lub sijhawm, qhov concentration ntawm cov tshuaj nquag hauv plasma tsis pom vim nws hloov pauv sai rau hauv cov metabolites nquag.
Cov tshuaj no tawm hauv lub cev nrog zis thiab quav.
Cov lus qhia rau kev siv
Thaum twg yog siv mycophenolate mofetil? Cov lus qhia rau kev siv yuav teb cov lus nug no sai sai.
Cov kws kho mob tau sau tshuaj los tiv thaiv kev tsis lees txais kev tso ntshav siab hauv cov neeg mob tom qab hloov lub raum, siab lossis lub plawv.
Contraindications rau kev siv
Tsis muaj ntau qhov xwm txheej uas kev siv tshuaj "Mycophenolate mofetil" raug txwv nruj heev. Cov no suav nrog tus neeg mob qhov tsis txaus siab rau cov khoom tseem ceeb lossis lwm yam khoom ntawm cov tshuaj, nrog rau thaum cev xeeb tub thiab lactation.
Qhov kev ua tau zoo thiab kev nyab xeeb ntawm cov tshuaj hauv kev kho menyuam yaus tsis tau txheeb xyuas, yog li nws yuav tsum tsis txhob siv rau hauv kev kho menyuam yaus.
Side effects
Mycophenolate mofetil tuaj yeem ua rau qee qhov kev phiv. Nws siv ua ke nrog corticosteroids thiab cyclosporine tuaj yeem ua rau raws plab, ntuav, sepsis thiab leukopenia. Qee zaum, kev loj hlob ntawm lymphomas thiab lwm yam kab mob malignant, tshwj xeeb ntawm daim tawv nqaij, tau pom.
Ntxiv rau, txhua tus neeg mob nrogkev hloov pauv yog qhov pheej hmoo ntawm kev tsim cov kab mob sib kis uas tau tshwm sim los ntawm cov kab mob kis tau zoo. Feem ntau ntawm lawv yog herpes, candidiasis thiab cytomegalovirus.
Lwm yam kev phiv tshwm sim muaj xws li herpes zoster, urinary tract infection, nasopharyngitis, hyperthermia, hepatic dysfunction, esophagitis, gastrointestinal los ntshav, kab mob ua pa sab sauv, hnoos, mob taub hau, gastroenteritis, qaug zog, sinusitis, panancyitis, pulmonary candidiasis. neuropenia thiab lwm yam.
Muaj kev hem thawj hnyav, thiab qee zaum txawm tias muaj xwm txheej txaus ntshai, xws li tuberculosis, kab mob endocarditis, kab mob atypical mycobacterial.
Txoj kev tswj hwm thiab noj ntau npaum li cas
Yuav siv cov tshuaj "Mycophenolate mofetil" li cas? Cov lus qhia nrog rau nws muab cov ntaub ntawv hauv qab no.
Kev tiv thaiv lub raum tsis lees paub. Thawj koob tshuaj yuav tsum tau muab coj los siv hauv 72 teev tom qab hloov pauv. Yav tom ntej, tus neeg mob yuav tsum noj 1 g ob zaug ib hnub.
Mycophenolate mofetil feem ntau yog muab nrog corticosteroids thiab cyclosporine.
Kev tiv thaiv lub plawv tsis lees paub. Thawj koob tshuaj yuav tsum tau noj tsis pub dhau 5 hnub tom qab ua haujlwm. Nyob rau hauv lub neej yav tom ntej, tus nqi ntawm cov nyiaj yuav tsum yog 1.5 g ob zaug ib hnub
Ntau tshaj
Tsis muaj cov ntaub ntawv tshaj tawm rau Mycophenolate Mofetil.
Cov khoom tsis tuaj yeem tshem tawm ntawm lub cev los ntawm hemodialysis. Cov tshuaj uas khi cov kua tsib acids (cholestyramine) tuaj yeem pab tshem tawm MPA ntawm lub cev los ntawm kev ua kom nws tso tawm.
Daim ntawv thov nta
Yog tias tus neeg mob tau kuaj pom tias muaj tus kab mob neuropenia, nws yuav tsum tau txo cov koob tshuaj thiab ua tib zoo saib xyuas tus neeg mob lub xeev kev noj qab haus huv lossis cuam tshuam kev kho mob nrog mycophenolate mofetil.
Thaum muaj lub raum tsis ua haujlwm hnyav, koj yuav tsum ua tib zoo saib xyuas koj txoj kev noj qab haus huv thiab tsis txhob tshaj qhov ntau ntawm cov tshuaj, uas qhov no nce mus txog 2 g ib hnub twg.
Cov neeg laus (txog 65 xyoos) raug pom zoo kom siv 1 g ntawm cov tshuaj 2 zaug hauv ib hnub.
Tsis muaj ntaub ntawv qhia txog qhov ua tau zoo ntawm cov tshuaj hauv kev kho mob ntawm cov neeg mob lub raum tsis txaus uas tau txais daim siab lossis lub plawv hloov pauv. Kuj tseem tsis tau muaj ntaub ntawv qhia tias cov tshuaj muaj txiaj ntsig zoo li cas rau cov neeg mob lub siab puas tsuaj uas tau txais kev phais hloov lub plawv.
Kev Tiv Thaiv
Tsis muaj teeb meem koj yuav tsum qhib lub capsule nrog cov tshuaj. Tsis txhob sib chwv ncaj qha nrog cov hmoov: nqus tau pa, tiv nrog daim tawv nqaij los yog mucous daim nyias nyias. Yog tias qhov no tshwm sim, koj yuav tsum ntxuav cov chaw uas cuam tshuam nrog xab npum thiab dej tam sim.
txhais tau tias analogues
Puas muaj cov tshuaj uas tuaj yeem hloov cov tshuaj "Mycophenolate mofetil"? Ntawm chav kawm, muaj analogues. Lawv yogmuaj tib lub INN (lub npe thoob ntiaj teb tsis yog tswv) lossis ATC code. Tsuas yog qhov ntau ntawm cov nyiaj thiab lawv cov nqi yuav txawv me ntsis.
Ntse nrov tshaj plaws yog cov tshuaj hauv qab no:
- "Buxmoon". Siv ua ke nrog corticosteroids thiab cyclosporine los tiv thaiv kev tsis kam ntawm lub plawv, siab, lossis raum tom qab hloov pauv.
- "Zenapax". Siv los tiv thaiv kev hloov lub raum tsis lees paub ua ke nrog cyclosporine GCS.
- "Imusporin". Nws yog siv rau kev tiv thaiv thiab kho cov kab mob hloov pauv thiab cov pob txha pob txha, nrog rau kev mob caj dab rheumatoid, endogenous uveitis, Behçet's kab mob, kab mob lupus erythematosus thiab lwm yam kab mob.
- "Imufet". Raws li cov tshuaj tseem ceeb, cov tshuaj tau muab tshuaj ua ke nrog corticosteroids thiab cyclosporine los tiv thaiv kev tsis lees txais lub siab hloov pauv lossis lub raum.
- "Lub Neej". Cov cuab yeej muaj qhov dav spectrum ntawm kev ua. Nws tuaj yeem siv los tiv thaiv thiab kho qhov tsis lees txais cov kab mob hloov pauv thiab cov pob txha pob txha, nrog rau kev mob caj dab, nephrotic syndrome, cov ntaub ntawv nquag ntawm cov kab mob lupus erythematosus, Behcet's kab mob, endogenous uveitis thiab lwm yam kab mob.
- "Myfenax". Cov lus qhia rau kev siv yog tib yam li cov cuab yeej tseem ceeb.
- "Myfortic". Tsim los tiv thaiv lub raum tsis lees txais.
- "Mofilet". Indications thiab txoj kev ntawm daim ntawv thov yog zoo ib yam limycophenolate mofetil.
- "Panimoon". Siv rau hauv kev hloov pauv ntawm lub ntsws, lub plawv, lub raum, cov pob txha pob txha, pancreas, nrog rau qee yam kab mob.
- "Cellcept". Tej zaum yuav raug sau rau kev hloov raum.
- "Sertikan". Pom zoo rau cov neeg mob hloov lub raum lossis lub plawv uas muaj kev pheej hmoo qis lossis tsis muaj kev tiv thaiv kab mob.
- "Cycloral". Siv ua ke nrog lwm cov tshuaj hauv kev hloov pauv hauv nruab nrog cev.
- "Equoral". Nws yog siv rau kev hloov pauv ntawm cov kabmob parenchymal, nrog rau kev tiv thaiv ntawm lawv qhov kev tsis lees paub tom qab hloov pauv.
Txawm hais tias lawv txhua tus muaj qhov zoo sib xws, ua ntej hloov cov tshuaj tseem ceeb nrog lwm yam, koj yuav tsum xub sab laj thiab sab laj nrog koj tus kws kho mob.
