Yog tias koj tus kws kho mob tau kuaj pom tus kab mob "kab mob", qhov no txhais tau tias nws yuav tsum tau kho kom zoo. Ib pab pawg neeg coob ntawm peb cov pej xeem ntseeg tias cov tshuaj tua kab mob yog cov tshuaj zoo tshaj plaws rau txhua yam kab mob. Hmoov tsis zoo, qhov kev xav yuam kev no tuaj yeem ua rau muaj kev phom sij ntau dua li qhov tsis zoo nws tus kheej. Cov tshuaj tua kab mob tsuas yog tawm tsam kab mob, thiab lawv tsis muaj zog tiv thaiv kab mob.
tshuaj ua haujlwm li cas?
Muaj ntau cov tshuaj uas muaj tshuaj tiv thaiv kab mob. Ib qho ntawm cov khoom siv tshaj plaws nrog cov cuab yeej no yog pentanedioic acid imidazolylethanamide.
Nws muaj zog tiv thaiv kab mob khaub thuas A thiab B kab mob, adenoviruses, pab nrog parainfluenza thiab ua pa syncytial kab mob.
Cov tshuaj nquag no muaj cov txheej txheem tshwj xeeb ntawm kev ua. Nws inhibits cov txheej txheem kev loj hlob ntawm cov kab mob nyob rau theem nuclear, thiab tseem ncua kev tsiv teb tsaws. Cov tshuaj tua kab mob tshiab tau tsim los ntawm cytoplasmic nruab nrab mus rau lub cell nucleus.
Tsis tas li, pentanedioic acid imidazolylethanamide nquag koom nrog hauv tib neeg lub cev tiv thaiv kab mob, ua rau muaj kev hloov pauv. Cov tshuaj tsub kom cov ntsiab lus ntawm interferon nyob rau hauv cov ntshav mus rau theem ntawm physiological cai. Nws kuj tseem muaj cov nyhuv stimulating rau cov txheej txheem ntawm α-, γ-interferon ntau lawm los ntawm leukocytes, nqa cov haujlwm no rau hauv lub xeev tsim nyog.
Kev tshawb fawb ntawm cov tshuaj nquag no tau pom tias pentanedioic acid imidazolylethanamide txhawb kev tsim cov cytotoxic lymphocytes. Tsis tas li ntawd, nws nce tus naj npawb ntawm NK-T cov neeg ua haujlwm, uas muaj peev xwm tsis muaj peev xwm ua kom puas hlwb hloov los ntawm cov kab mob, thiab tseem ua ncaj qha rau cov kab mob sib kis.
Qhov zoo ntawm cov tshuaj yog tias nws muaj cov tshuaj tiv thaiv kab mob. Lawv tau muab los ntawm kev tsim cov cytokines profile, nrog rau kev txo qis hauv kev ua haujlwm ntawm enzyme myeloperoxidase.
Cov nyhuv kho tau
Imidazolyl ethanamide pentanedioic acid, tshuaj xyuas ntawm qhov zoo, nthuav tawm cov txiaj ntsig kho mob hauv qab no hauv kev kho mob SARS thiab mob khaub thuas:
- Txo lub sijhawm ntawm cov txheej txheem tsis txaus.
- Txo cov cim ntawm lub cev qaug cawv (kiv taub hau, mob, tsis muaj zog).
- Txo tus naj npawb ntawm catarrhal manifestations.
- Txhim txo cov teeb meem ntawm kev mob yav dhau los.
- Shortenslub sij hawm muaj mob.
Pentanedioic acid imidazolylethanamide npaj
Hauv lub tsev muag tshuaj koj tuaj yeem pom cov tshuaj hauv qab no uas muaj imidazolylethanamide pentanedioic acid:
- "Vitaglutam" hauv daim ntawv ntawm hmoov.
- "Ingavirin" hauv daim ntawv tshuaj ntsiav.
- Dicarbamine ntsiav tshuaj.
YContraindications
Zoo li txhua yam tshuaj, pentanedioic acid imidazolylethanamide yog cov tshuaj uas yuav tsum tau muab los ntawm koj tus kws kho mob. Cov khoom lag luam tshuaj no muaj contraindications, suav nrog:
- YKev cev xeeb tub thiab lactation.
- Cov menyuam yaus hnub nyoog qis dua 18.
- Ib tug neeg intolerance rau lub Cheebtsam ntawm cov tshuaj.
Cov kev mob tshwm sim los ntawm kev noj tshuaj uas muaj cov tshuaj uas tau piav qhia tuaj yeem qhia tau tias yog kev tsis haum tshuaj.
Cov nyhuv no tshwm sim nyob rau hauv cov xwm txheej uas ib tug neeg muaj ib tus neeg rhiab heev rau pentanedioic acid imidazolylethanamide los yog rau excipients uas yog ib feem ntawm cov tshuaj.
Kev nyab xeeb
Qee tus neeg nyiam zam cov tshuaj no, ntseeg tias pentanedioic acid imidazolylethanamide yog tshuaj tua kab mob. Qhov kev xav no yog qhov yuam kev, txij li cov khoom siv no tsuas yog muaj kev tiv thaiv kab mob. Lub npe zoo deprives nws ntawm tag nrho cov kev mob tshwm sim uas muaj nyob rau hauv cov tshuaj antimicrobial. Cov khoom siv tshuaj no tsis muaj tshuaj tiv thaiv kab mob, carcinogenic,mutagenic lossis allergenic, tsis ua rau mob plab, tsis txo qis kev ua me nyuam, tsis muaj teratogenic lossis embryotoxic nyhuv.
Ib qho kev ua haujlwm siab ntawm cov tshuaj uas muaj imidazolylethanamide pentanedioic acid, analogues ntawm qhov ncauj, tau raug sau tseg. Lawv sai sai absorbed nyob rau hauv lub plab hnyuv ib ntsuj av thiab sib npaug zos faib nyob rau hauv lub cev thiab cov ntaub so ntswg. Twb ib nrab ib teev tom qab noj, cov tshuaj no nce mus txog nws qhov siab tshaj plaws concentration thiab khaws cia hauv cov ntshav rau 37 teev. Lub sijhawm kho yog 5 hnub. Nrog rau txhua koob tshuaj, muaj dhia hauv nws cov ntsiab lus hauv cov ntshav, uas maj mam txo qis thaum nruab hnub. Cov tshuaj tsis yog metabolized nyob rau hauv tib neeg lub cev, nws yog excreted unchanged los ntawm ob lub raum thiab cov hnyuv.
Reception Feature
Nws yog ib qho tseem ceeb heev uas yuav tsum ua raws li kev noj tshuaj rau cov tshuaj no. imidazolylethanamide pentanedioic acid, nws cov analogues yog tus cwj pwm los ntawm kwv yees li tib qhov kev pom zoo rau kev siv, yuav tsum tau noj ib hnub ib zaug hauv qhov nyiaj ntawm 90 mg rau lub sijhawm 5-7 hnub, tsis hais txog kev noj zaub mov.
Qhov peculiarity ntawm kev kho mob nrog tus neeg sawv cev tshuaj no yog qhov ua tau zoo tshaj plaws yog ua tiav thaum noj tom qab kuaj pom thawj zaug ntawm tus kab mob hauv thawj ob hnub.
Vitaglutam yog lub hauv paus ntawm ib pawg tshuaj tiv thaiv kab mob
Keeb kwm ntawm cov tshuaj no rov qab mus rau 70s ntawm xyoo pua xeem. Nws tau tsimnto moo Lavxias teb sab pulmonologist Alexander Chuchalin. Cov khoom siv tshuaj no muaj pentanedioic acid imidazolylethanamide ua cov khoom xyaw tseem ceeb. "Vitaglutam" txog 2008 tau nthuav tawm rau kev muag khoom raws li lub npe lag luam "Dicarbamine". Nws lub hom phiaj yog los txhawb cov txheej txheem ntawm hematopoiesis hauv cov neeg mob uas tau kho mob qog noj ntshav.
Hauv xyoo 2009, tib neeg tau ntsib kev kis tus kab mob txaus ntshai - swine flu, lossis A/H1N1. Lub sijhawm no, kev txhim kho ntawm Vitaglutam tau dhau los ua qhov tseem ceeb heev. Alexander Chuchalin, uas nyob rau lub sijhawm ntawd yog tus kws kho mob tseem ceeb ntawm Lavxias Federation, tau txiav txim siab sim nws cov xeeb ntxwv tiv thaiv tus kab mob swine flu thiab ua tiav cov txiaj ntsig zoo. Nws tau hais tias cov tshuaj hauv tsev, uas yog ua raws li pentanedioic acid imidazolylethanamide, Vitaglutam, muaj txiaj ntsig zoo dua tiv thaiv kab mob ntau dua li Asmeskas cov khoom lag luam tshuaj Tamiflu. Nws nquag koom ua ke rau hauv cov kab mob genome thiab rhuav tshem nws.
Lub neej tshiab ntawm Vitaglutam: Ingavirin
Chuchalin tau thov rau Gennady Onishchenko, tus kws kho mob tus thawj saib xyuas kev noj qab haus huv ntawm Lavxias Federation, siv nws cov khoom tsim los ua cov cuab yeej zoo hauv kev kho mob swine flu. Raws li qhov tshwm sim, kev sim tshuaj ntawm cov tshuaj tau ua tiav, thaum lub sijhawm nws tau lees paub nws cov txiaj ntsig tiv thaiv ntau yam kab mob. Cov tshuaj tau txais lub npe tshiab "Ingavirin" thiab tau sau npe rau hauv cov npe ntawm ib pawg tshuaj tiv thaiv kab mob thiab tshuaj tiv thaiv kab mob.
Tom qab cov khoom lag luam ntawm lub tuam txhab tshuaj "Valenta" tau muag, nws tau raug pom zoo los ntawm Ministry of He alth raws li kev kho mob khaub thuas swine thiab pib ua txhaum cov ntaub ntawv muaj koob npe ntawm cov pejxeem. Yog li, peb tuaj yeem hais txog qhov sib npaug "Dicarbamine" - imidazolylethanamide ntawm pentanedioic acid - "Vitaglutam", qhov no yog, qhov tseeb, tib cov tshuaj.
Nws tsim nyog sau cia qhov tseeb tias Ingavirin tau muag hauv xyoo 2008 yam tsis muaj kev sim tshuaj tag nrho. Nrog kev pab ntawm Onishchenko hauv xyoo 2009, kev sim tshuaj sai sai ntawm cov nas hauv chav kuaj tau raug teeb tsa. Kwv yees li ntawm 100 tus neeg mob kuj tau koom nrog qhov xwm txheej no. Raws li cov txiaj ntsig tau txais thaum lub sijhawm kawm, ib pab pawg kws tshawb fawb coj los ntawm Chuchalin xaus lus tias Ingavirin tau pom tias muaj txiaj ntsig zoo tiv thaiv kab mob hauv thawj 48 teev txij li qhov pib kis. Nws qhov kev txiav txim tau hais tawm hauv kev txo qis ntawm lub sijhawm febrile, txo qis ntawm kev qaug cawv ntawm cov neeg mob thiab cov tsiaj kuaj thiab txo cov catarrhal manifestations.
Yog li ntawd, tsis muaj laj thawj xav tias pentanedioic acid imidazolylethanamide yog ib qho dummy - nws cov txiaj ntsig tau raug pov thawj hauv kev kho mob.
Dicarbamine hnub no
Tam sim no, tag nrho peb cov tshuaj raws li imidazolylethanamide pentanedioic acid yog cov muag khoom thiab muab tso rau hauv qhov sib piv ntawm ib leeg.
Dicarbamine raug pom zoo rausiv los ntawm cov neeg mob qog nqaij hlav malignant. Ntxiv nrog rau cov khoom xyaw tseem ceeb, nws muaj cov mis nyuj qab zib, talc, qos starch, magnesium stearate, colloidal silicon dioxide thiab stearic acid.
"Dicarbamine" muaj cov teebmeem hauv qab no:
- Acceleration ntawm neutrophil sib txawv thiab lawv ua haujlwm kom loj hlob.
- Hematoprotection hauv myelosuppressive chemotherapy.
- Txo qhov tshwm sim thiab qib ntawm cov tshuaj lom neutropenia, txo qis leukopenia.
Cov tshuaj no raug pom zoo rau kev siv ntawm cov chav kawm chemotherapy.
Nws siv tau tom qab 21-28 hnub ntawm kev noj cov ntsiav tshuaj txhua hnub.
Ib koob tshuaj ib zaug - 100 mg (1 ntsiav tshuaj) - noj 5 hnub ua ntej pib kev kho mob thiab txuas ntxiv mus thoob plaws hauv kev kho mob. "Dicarbamine" muaj peev xwm txhim kho thiab ua kom ntev ntawm cov tshuaj tiv thaiv kab mob cytostatics, txo cov tshuaj lom ntawm cyclophosphamide thiab platinum-based tshuaj, thiab kuj normalize hematopoiesis.
