Kab mob peptic cuam tshuam rau tib neeg tsis hais lawv lub hnub nyoog, poj niam los yog txiv neej li cas. Yog li ntawd, nws yog ib qho tseem ceeb heev uas yuav daws tau qhov teeb meem yam tsis muaj kev phiv loj heev. Ib qho ntawm cov kev daws teeb meem no tuaj yeem suav hais tias yog bismuth subcitrate, uas tsis tsuas yog rhuav tshem cov kab mob uas ua rau mob plab, tab sis kuj tiv thaiv nws qhov chaw los ntawm kev tsim cov yeeb yaj kiab rau nws.
Pharmacological action
Cov txiaj ntsig tseem ceeb ntawm cov tshuaj yog txhawm rau tshem tawm cov kab mob Helicobacter pylori, uas ua rau muaj kab mob thiab yaig ntawm lub plab thiab duodenum. Tsis tas li ntawd, nyob rau hauv ib puag ncig acidic ntawm lub plab, bismuth subcitrate tsim cov yeeb yaj kiab tiv thaiv uas tiv thaiv lub plab los ntawm kev puas tsuaj.
Tsis tas li ntawd, nws txhawb nqa kev ua haujlwm ntawm nws tus kheej cytoprotective mechanisms, nce cov synthesis ntawm prostaglandins thiab bicarbonates. Yog li ntawd, tom qab noj cov tshuaj, tsis yog tsuas yog ua rau lub qhov txhab raug tshem tawm, tab sis kujnce kev tiv thaiv ntawm txoj hnyuv. Txhawm rau hloov bismuth mus rau hauv cov yeeb yaj kiab tiv thaiv, yuav tsum muaj acidic ib puag ncig ntawm cov kua txiv hmab txiv ntoo.
Kev qhia
Cov lus qhia tseem ceeb rau kev noj bismuth subcitrate yog peptic ulcer ntawm lub plab thiab duodenum, tshwm sim los ntawm kev cuam tshuam ntawm cov kab mob Helicobacter pylori. Tsis tas li ntawd, cov tshuaj tau qhia tias siv rau hauv gastritis (ob leeg cuam tshuam nrog cov kab mob thiab tsis), sab nraud rau cov kab mob ntawm daim tawv nqaij thiab eczema.
Cov tshuaj tau pom nws tus kheej zoo hauv kev kho mob ntawm plab hnyuv, uas tshwm sim vim siv cov tshuaj mus ntev los ntawm pab pawg ntawm cov tshuaj tsis-steroidal anti-inflammatory.
Kev qhia txog kev npaj bismuth rau hauv cov txheej txheem kho mob kuj tseem pab txhim kho kev tiv thaiv tag nrho ntawm lub plab yog tias tus neeg mob muaj kev pheej hmoo ntawm kev puas tsuaj.
Nyob rau hauv kev kho mob plab thiab duodenal rwj nrog tshuaj, cov tshuaj muaj ob qho tib si nyob rau hauv cov khoom siv rau txoj kev kho mob ntawm tus kab mob complex, thiab yog siv raws li ib tug tshuaj. Txawm li cas los xij, nws raug pom zoo, txawm li cas los xij, ua ke nrog lwm txoj kev. Qhov no yuav ua rau kom muaj kev kho sai sai.
Cov lus qhia rau kev siv
Raws li cov lus qhia rau kev siv bismuth subcitrate, zaus ntawm kev noj cov ntsiav tshuaj nyob ntawm lub hnub nyoog ntawm tus neeg mob. Ib tug neeg laus yuav tsum tau noj ib ntsiav tshuaj plaub zaug ib hnub twg, thaum tus menyuam hnub nyoog 8 txog 12 xyoos yuav tsum tau noj ib ntsiav tshuaj ob zaug ib hnub.
Tom qab noj tshuaj, noj me me dej. Lub sijhawm ntawm chav kawm nkag yog los ntawm 4 mus rau 8 lub lis piam, tom qab uas koj xav tausiv sijhawm tsawg kawg 8 lub lis piam so, thaum lub sijhawm nws tsis pom zoo kom noj tshuaj uas muaj bismuth.
Thaum muaj kev puas tsuaj los ntawm Helicobacter pylori, cov tshuaj nrog bismuth yog siv los ua ib feem ntawm kev sib xyaw ua ke thiab siv nruj raws li cov tswv yim: 1 ntsiav tshuaj ntawm bismuth subcitrate ob zaug hauv ib hnub, 1 ntsiav tshuaj ntawm clarithromycin ob zaug ib hnub. thiab 1 ntsiav tshuaj ntawm amoxicillin ob zaug ib hnub twg. Nws kuj tau pom zoo kom siv cov tshuaj proton twj tso kua mis hauv kev kho. Nrog rau daim ntawv no ntawm kev kho mob, kev npaj bismuth pab txhawb kev tiv thaiv siab tshaj plaws ntawm lub plab thiab duodenum.
Tom qab kev kho mob tiav, koj yuav tsum tau noj tshuaj bismuth txuas ntxiv txhawm rau tshem tawm qhov muaj peev xwm rov qab los thiab tiv thaiv lub plab los ntawm kev puas tsuaj. Nws raug nquahu kom txwv kev siv tshuaj rau 6 lub lis piam, vim tias siv cov tshuaj mus ntev tuaj yeem ua rau muaj kev phiv tsis zoo.
YContraindications
Txawm hais tias bismuth subcitrate yog suav tias yog tshuaj nyab xeeb, nws yuav tsum tsis txhob noj los ntawm cov neeg mob uas paub txog lub raum tsis zoo. Nws tseem tsim nyog, yog tias ua tau, hloov cov tshuaj yog tias tus neeg mob hnub nyoog qis dua 14 xyoos. Yog tias cev xeeb tub lossis pub niam mis, kev siv tshuaj raug tso cai nrog ceev faj.
Analogues
Bismuth subcitrate yog sawv cev ntawm cov khw muag tshuaj los ntawm cov tshuaj xws li "De-Nol", "Vis-Nol". Tsis tas li ntawd zoo sib xws hauv kev txiav txim yog cov tshuaj los ntawm cov pab pawg neeg antacid, vim lawv kuj muab kev tiv thaiv ntawm lub plab nrog kev pab ntawmcov yeeb yaj kiab ntawm nws sab hauv. Cov no suav nrog Almagel, Maalox, Rennie thiab ntau lwm tus.
Cov lus qhia tshwj xeeb
Kev siv yuav ua rau cov quav dub. Bismuth subcitrate thiab analogues yuav tsum tau cais tawm ntawm kev noj haus ntawm cov kua thiab cov khoom noj uas pab txo cov acidity ntawm lub plab, nrog rau cov tshuaj antacids. Qhov no yog ua tiav vim cov kua qaub kua qaub yog tsim nyog rau cov tshuaj los tsim cov yeeb yaj kiab tiv thaiv kab mob plab.
Nws yog qhov tsis xav tau siv cov tshuaj ntev ntev (ntau tshaj ob lub hlis), vim tias muaj kev pheej hmoo ntawm kev tsim mob encephalopathy. Txawm li cas los xij, qhov txiaj ntsig zoo li no tsis zoo li thaum pom cov koob tshuaj kom raug.
Muaj me me ntawm cov kev mob tshwm sim uas cuam tshuam nrog kev xav thiab mloog, yog li koj yuav tsum ceev faj thaum tsav tsheb thaum noj tshuaj muaj bismuth.
Thaum noj tshuaj nrog bismuth, koj yuav tsum tsis txhob siv lwm yam khoom uas muaj tib yam tshuaj. Kev siv ntau yam analogs tuaj yeem ua rau muaj qhov nce ntawm bismuth hauv cov ntshav thiab, vim li ntawd, qhov kev pheej hmoo ntawm kev tsim cov kev mob tshwm sim tsis zoo, suav nrog cov teebmeem ntawm lub paj hlwb.
