Gout yog ib yam kab mob uas tshwm sim los ntawm kev txhim kho ntawm kev mob caj dab vim yog qhov siab ntawm uric acid nyob rau hauv lub cev, uas ua rau muaj cov muaju hauv cov pob qij txha. Ib qho tshuaj xws li Allopurinol pab txo qis qib ntawm uric acid. Ntau tus kws kho mob tau sau cov tshuaj no rau tus kab mob no. Tsis yog txhua tus paub yuav ua li cas noj Allopurinol rau gout. Yuav tsum tau kho qhov no.
yam ntxwv thiab piav qhia ntawm cov tshuaj
Ua ntej teb cov lus nug seb puas tuaj yeem noj Allopurinol rau gout, koj yuav tsum paub seb cov tshuaj twg yog dab tsi, nws cuam tshuam rau lub cev li cas.
Qhov no yog ib qho tshuaj tiv thaiv kab mob uas cuam tshuam cov synthesis ntawm uric acid, uas muaj xws li cov tshuaj nquag xws li allopurinol hauv qhov ntau ntawm 100 lossis 300 milligrams. Cov tshuaj no yog ib qho inhibitor ntawm xanthine oxidase, uas tsim los ntawmxanthine uric acid.
Raws li cov khoom ntxiv hauv cov tshuaj muaj pes tsawg leeg yog: hmoov txhuv nplej siab, talc, magnesium stearate, lactose monohydrate, povidone, cellulose, gelatin thiab lwm yam.
Cov tshuaj muaj nyob rau hauv daim ntawv ntawm cov ntsiav tshuaj, uas tau muab tso rau hauv cov hlwv hauv qhov nyiaj ntawm 10 daim. Ib pob yuav muaj 3 lossis 5 hlwv. Tsis tas li ntawd, cov ntsiav tshuaj ntawm 30 lossis 50 daim tuaj yeem muab tso rau hauv lub raj mis xim tsaus.
Yuav ua li cas noj "Allopurinol" rau gout, tus kws kho mob yuav qhia thaum twg cov txiaj ntsig ntawm tus neeg mob cov kev sim qhia txog kev txhim kho hyperuricemia, tshwj xeeb tshaj yog tias nws ua rau muaj teeb meem hauv daim ntawv ntawm gout. Nyob rau hauv qhov tseeb, cov tshuaj yog siv systematically.
Ntxiv rau, cov tshuaj tau sau rau hauv cov xwm txheej zoo li no:
- Primary lossis secondary hyperuricemia ntawm ntau lub hauv paus.
- Nyob raum pob zeb.
- Radiation therapy.
- Kho nrog corticosteroids thiab cytostatics.
- YUrate Nephropathy.
- Urolithiasis, nrog rau qib siab ntawm uric acid hauv lub cev.
Gout Therapy
Yuav ua li cas noj "Allopurinol" rau gout, tus kws kho mob yuav qhia. Nyob rau hauv lub xub ntiag ntawm hyperuricemia, ib tug neeg mob gout dhau lub sij hawm vim lub deposition ntawm urate nyob rau hauv cov pob qij txha. Tus kab mob manifests nws tus kheej nyob rau hauv daim ntawv ntawm mob caj dab, o thiab mob. Yog li ntawd, cov neeg uas muaj xws li pathology yuav tsum paub yuav ua li cas noj Allopurinol thaum lub sij hawm exacerbation ntawm gout.
Cov tshuaj no tso tsegCov txheej txheem ntawm kev tsim cov uric acid, tshem tawm qhov mob, maj mam tshem tawm qhov ua rau kev loj hlob ntawm tus kab mob.
Lub hom phiaj ntawm txoj kev kho no yog:
- Txo cov foci ntawm urate tsim.
- Txo qhov loj ntawm tophi.
- Txo uric acid concentration rau 420 µmol / L.
- Txo qhov zaus ntawm kev tawm tsam gout.
Yuav ua li cas noj "Allopurinol" nrog exacerbation ntawm gout, kws kho mob tau paub ntev, txij li cov tshuaj no tau siv rau hauv cov tshuaj ntev ntev los kho hyperuricemia hauv tus kab mob no.
Kev kho mob
Kuv puas tuaj yeem noj "Allopurinol" nrog rau kev mob gout? Cov kws kho mob muab cov lus teb zoo. Cov tshuaj no txo cov qib ntawm uric acid nyob rau hauv cov ntshav thiab zis, yog li cov txheej txheem ntawm deposition ntawm nws cov crystals slows down. Nyob rau hauv lub cawv ntawm cov tshuaj, twb tsim crystals maj mam pib yaj.
Tom qab noj, cov tshuaj yaj zoo hauv cov hnyuv, nqus hauv cov hnyuv thiab duodenum, nce mus txog qhov siab tshaj plaws tom qab ib teev thiab ib nrab. Thaum pib ntawm kev kho mob, kev siv tshuaj ntau ntxiv yog ua tau.
Thaum siv cov tshuaj ntawm ib koob ntawm 100 milligrams, bioavailability yog 67%, thaum noj ntawm 300 milligrams - 90%.
Lub neej ib nrab yog ob teev. Cov tshuaj nquag tsis khi rau cov ntshav plasma protein, 80% ntawm nws tau tawm los ntawm lub raum, tus so nrog rau cov quav.
Kev nyem tshwm sim thaum siv tshuaj rau ob peb lub hlis. Cov tshuaj muaj txiaj ntsig zoo.
Yuav ua li cas noj Allopurinol rau gout: ntau npaum li cas, cov cai tswj hwm
Ua ntej pib kho, nws raug nquahu kom kawm cov lus qhia rau kev siv cov tshuaj, contraindications, uas yog piv nrog lub xeev kev noj qab haus huv ntawm txhua tus neeg mob. Yog tias tsis ntseeg, koj yuav tsum sab laj nrog koj tus kws kho mob.
Cov ntsiav tshuaj tau noj tom qab noj mov, tsis txhob zom thiab ntxuav nrog dej huv uas tsis yog carbonated. Thaum lub sijhawm kho, koj yuav tsum haus dej kom txaus txhua hnub, ua raws li qee yam kev noj haus kom ua rau kom cov kua dej ntau ntxiv thiab tswj cov diuresis ib txwm.
Cov neeg laus thiab cov menyuam yaus hnub nyoog tshaj kaum xyoo yuav tsum tau noj 100 lossis 300 milligrams ntawm cov tshuaj ib hnub. Thaum xub thawj, nws raug nquahu kom noj ib ntsiav tshuaj ntawm 100 mg ib hnub, tom qab ntawd cov koob tshuaj maj mam nce, nce nws los ntawm 100 mg ntawm cov tshuaj txhua lub lis piam. Yog li ntawd, rau lub lim tiam thib peb, koj yuav tsum tau siv cov tshuaj ntawm 300 mg ib hnub twg.
Thaum mob hnyav, tus kws kho mob yuav muab 600 lossis 800 mg rau ib hnub. Hauv qhov no, cov koob tshuaj tau muab faib ua 2, 3 lossis 4 koob ntawm ib ntus. Qhov siab tshaj plaws txhua hnub yuav tsum tsis pub tshaj 800 mg ntawm cov tshuaj.
Cov menyuam yaus hnub nyoog 3 txog 6 xyoo tau muab tshuaj rau hauv tus nqi ntawm 5 mg ib kg ntawm lub cev hnyav, cov menyuam yaus hnub nyoog 6 txog 10 xyoo - 19 mg / kg. Lawv yuav tsum tau noj cov tshuaj peb zaug ib hnub twg. Hauv qhov no, qhov siab tshaj plaws txhua hnub yuav tsum tsis pub tshaj 400 milligrams.
Rau cov neeg mob nrogLub raum ua haujlwm tsis zoo, cov tshuaj tau muab tshuaj ntawm 100 mg ib hnub, thaum tab tom kho hemodialysis - 300 mg tom qab txhua txoj kev 2 lossis 3 zaug hauv ib lub lis piam.
Ntau tus neeg txaus siab rau lo lus nug ntawm pes tsawg hnub kom noj Allopurinol rau gout. Yam tsawg kawg ntawm kev kho mob yog li plaub lub hlis. Thaum lub sijhawm no, qib uric acid yog normalized. Gout tawm tsam nres tom qab 6-12 lub hlis txij li pib kho.
Ntev npaum li cas yuav noj "Allopurinol" rau gout, noj npaum li cas, tus kws kho mob yuav qhia. Nws raug tso cai siv cov khoom siv tshuaj rau peb xyoos nrog luv luv.
Nws yog qhov tsim nyog yuav tsum tshem cov tshuaj maj mam. Txwv tsis pub, tus kab mob no ua tau.
Ntau npaum li cas yuav noj Allopurinol rau gout? Cov kws kho mob hais tias nws yuav siv li ntawm 6 mus rau 12 lub hlis txhawm rau tshem tawm qhov mob hnyav. Nws yuav siv sij hawm tib lub sij hawm rau cov deposits uas twb muaj lawm kom yaj thiab tawm hauv lub cev. Tom qab cov tsos mob ntawm pathology tau raug tshem tawm, cov tshuaj tau txuas ntxiv mus rau qhov tsawg kawg nkaus koob tshuaj raws li prophylaxis. Nws raug pom zoo kom coj noj qab haus huv thiab noj zaub mov zoo thaum lub sijhawm no.
Siv txwv
Y Koj tuaj yeem noj "Allopurinol" rau qhov ua rau mob gout, tab sis tsis yog txhua tus. Muaj qee qhov contraindications hauv kev siv tshuaj:
- High susceptibility to drug ingredients.
- raum tsis ua haujlwm hnyav.
- Pathology ntawm lub siab.
- Cov menyuam yaus hnub nyoog qis dua peb xyoos.
- Lub sijhawm xeeb tub thiab pub niam mis rau menyuam.
- Kev txo qis creatinine tshem tawm (tsawg dua 2 ml / min).
- YHemochromatosis.
- Yog tias qib uric acid tuaj yeem tswj tau los ntawm kev noj zaub mov.
Puas Allopurinol puas tuaj yeem noj rau gout flare-ups los ntawm cov neeg muaj lub raum lossis lub siab tsis ua haujlwm? Cov kws kho mob hais tias nyob rau hauv cov xwm txheej zoo li no, cov tshuaj tau sau nrog ceev faj. Nws tseem raug saib xyuas los ntawm cov neeg uas muaj qhov tsis zoo hematopoiesis, lub plawv tsis ua haujlwm, ntshav siab, thaum tab tom kho nrog diuretics thiab angiotensin-hloov enzyme inhibitors.
Recommendations
Rau thawj ob lub lis piam ntawm kev kho mob nrog cov tshuaj no, cov neeg mob gout yuav tsum tau ceev faj. Qhov no yog vim qhov tshwm sim ntawm exacerbation ntawm pathology. Cov kws kho mob feem ntau sau tshuaj loog ntxiv lossis colchicine thaum lub sijhawm no.
Ua ntej kawg ntawm kev kho mob, nws raug nquahu kom tswj hwm qhov concentration ntawm uric acid hauv lub cev. Rau qhov no, kuaj zis yog ua. Nrog rau kev siv cov tshuaj kom raug rau hnub thib ob ntawm kev kho mob, cov kev ntsuam xyuas yuav pom cov kev hloov pauv hauv cov kev coj zoo. Tsis tas li ntawd, kev sim yuav tsum tau ua kom tsis txhob ua rau muaj kev siv tshuaj ntau dhau thiab kho cov kev kho mob raws sijhawm.
Kev txhim kho ntawm qhov tsis zoo tshwm sim
Ua ntej pib kho, tus kws kho mob yuav qhia koj ntev npaum li cas thiaj noj Allopurinol rau gout, nrog rau cov kev tshwm sim tshwm sim. Cov no suav nrog:
- furunculosis;
- ntshav qab zib, leukocytosis, leukopenia;
- fever;
- daim tawv nqaij;
- kev txhim kho ntshav qab zib;
- kev nyuaj siab, mob taub hau;
- pom qhov tsis pom kev;
- angina;
- nce ntshav siab;
- kab mob siab;
- xeev siab thiab ntuav;
- tus kab mob Stevens-Johnson;
- plaub hau hloov;
- raum tsis ua haujlwm;
- erectile kawg;
- gynecomastia;
- vasculitis;
- eosinophilia;
- tawm pob ntawm daim tawv nqaij;
- o thiab khaus;
- ntshav qab zib;
- daim siab necrosis;
- tus kab mob;
- cataract;
- coma;
- paresthesia;
- bradycardia;
- mob pob qij txha;
- nce hauv lub cev kub.
Feem ntau, cov tsos mob no tshwm sim nrog ib koob tshuaj ntawm ib koob tshuaj loj thiab muaj teeb meem kev noj qab haus huv. Yog li ntawd, nws yog ib qho tsim nyog yuav tsum paub koj tus kheej ua ntej nrog kev siv tshuaj npaum li cas, siv sijhawm ntev npaum li cas Allopurinol rau gout. Tab sis feem ntau cov tshuaj tau txais txiaj ntsig zoo los ntawm cov neeg mob. Ua rau muaj qhov tsis zoo tshwm sim tuaj yeem ua tsis tau zoo, dhau ntawm cov koob tshuaj tso cai thiab tus neeg intolerance rau cov khoom ntawm cov tshuaj.
Yog tias muaj cov tsos mob tshwm sim, cov tshuaj yuav tsum raug tso tseg thiab koj yuav tsum hu rau lub tsev kho mob.
Ntau tshaj
Thaum cov koob tshuaj tau tso cai dhau lawm, tus neeg tau ntsib cov tsos mob tsis zoo:
- kiv taub hau;
- xeev siab thiab ntuav;
- mob plab;
- pob khaus;
- fever;
- hyperthermia;
- exacerbation ntawm lub raum pathologies;
- kab mob siab.
Kev kho mob hauv qhov no yog cov tsos mob, hydration thiab hemodialysis kuj tau siv. Tsis muaj tshuaj tua kab mob tshwj xeeb tau tsim hauv tshuaj.
Xav paub ntxiv
Thaum kawm txog kev kho mob, nws yuav tsum ua tib zoo tsav tsheb lossis lwm yam txheej txheem nyuaj, vim tias kev pheej hmoo ntawm kev qaug zog thiab kiv taub hau nce ntxiv.
Koj tsis tuaj yeem muab cov tshuaj thiab cov dej cawv sib xyaw ua ke, vim qhov kawg ua rau muaj kev nce hauv uric acid thiab ua rau tus kab mob hnyav dua. Thaum noj tshuaj thiab cawv, ntuav, raws plab, apathy thiab convulsions tuaj yeem tshwm sim, thiab los ntshav hauv cov kabmob sab hauv kuj tuaj yeem tshwm sim. Txhua yam dej cawv, txawm tias qaug zog thiab noj me me, tuaj yeem ua rau coma thiab lub plawv tsis ua haujlwm.
Ua ntej noj Allopurinol rau gout, koj yuav tsum tau xyuam xim rau qhov tseeb tias salicylates, probenecid thiab lwm yam tshuaj uas tshem tawm uric acid txo cov nyhuv ntawm cov tshuaj.
Thaum noj ampicillin, captopril lossis amoxicillin tib lub sijhawm, qhov tshwm sim ntawm daim tawv nqaij yuav nce ntxiv.
Khaws cov tshuaj rau hauv qhov chaw qhuav qhov cua kub ntawm kaum tsib mus rau nees nkaum tsib degrees. Lub txee lub neej yog tsib xyoos txij li hnub tso tshuaj.
Koj yuav tsum paub yuav ua li cas noj Allopurinol rau gout, thiab ua raws li cov lus qhia raws nraim. Qhov kev ua tau zoo ntawm cov tshuaj yuav tshwm sim tsuas yog thaum tus neeg mob ua raws li tag nrho cov tshuaj thiabkws kho mob cov lus pom zoo, nws yog txwv tsis pub hloov cov tshuaj ntawm koj tus kheej. Cov kev ua zoo li no tuaj yeem ua rau muaj teeb meem.
Nqi thiab yuav tshuaj
Koj tuaj yeem yuav tshuaj hauv qee lub khw muag tshuaj lossis khw muag tshuaj online. Koj xav tau tus kws kho mob cov tshuaj kom yuav nws. Tus nqi ntawm cov tshuaj yuav nyob ntawm seb tus naj npawb ntawm cov ntsiav tshuaj hauv lub pob thiab lawv qhov ntau npaum li cas. Tus nqi yuav zoo li no:
- 50 ntsiav tshuaj ntawm 100 mg - los ntawm 94 txog 106 rubles.
- 30 ntsiav tshuaj ntawm 300 mg - los ntawm ib puas mus rau ib puas thiab plaub caug rubles.
Analogues
Muaj pes tsawg tus analogues ntawm cov tshuaj no. Cov no suav nrog:
- Allupol.
- Purinol.
- Alopron.
- "Allohexal".
- Febux-40.
Reviews
Kev tshuaj xyuas txog cov tshuaj feem ntau yog qhov zoo. Ntau tus nco ntsoov tias nws muab qhov txiaj ntsig zoo ruaj khov, muaj tus nqi qis. Qee tus neeg tham txog kev hla ib ntsiav tshuaj thiab tsis noj ob ntsiav tshuaj tib lub sijhawm thaum muaj kev phiv tshwm sim.
Muaj ntau tus hais tias qhov ua tau zoo ntawm cov tshuaj yuav nce ntxiv yog tias thaum lub sijhawm kho koj haus dej ntshiab txaus thiab ua raws li kev noj haus.
Zoo kawg
"Allopurinol" hnub no yog suav tias yog cov tshuaj zoo tshaj plaws rau kev mob gout. Tab sis, hmoov tsis, nws tsis muaj peev xwm kom tshem tau tus kab mob tag nrho. Cov tshuaj nres nws txoj kev loj hlob, normalizes metabolism, tshem tawmCov tsos mob tsis zoo, ua rau nws muaj peev xwm ua tiav qhov kev tso siab ntev ntev.
Cov tshuaj feem ntau zam tau zoo. Hauv cov xwm txheej cais, cov tshuaj tsis muaj txiaj ntsig txawm tias qhov ntau npaum li cas.
