Creatinine yog cov khoom kawg ntawm cov tshuaj tiv thaiv creatine-phosphate, tsim los ntawm kev tawg ntawm cov protein molecules thiab amino acids. Nws yog nyob rau hauv lub npe hu ua "tsis yog-threshold" tshuaj uas yog lim los ntawm lub raum glomeruli (glomeruli) thiab tsis reabsorbed los yog secreted nyob rau hauv lub tubules. Kev nce hauv cov ntshav creatinine yog qhov muaj txiaj ntsig zoo rau kev kuaj mob nephrological, pathologies ntawm cov leeg nqaij, thiab xav tias lub cev qhuav dej.
ntsuas ntsuas ntsuas
Creatinine yog tsim los ntawm cov dej tsis-enzymatic thiab dephosphorylation ntawm creatine phosphate. Los ntawm cov leeg nqaij, cov metabolite nkag mus rau hauv cov hlab ntsha thiab yuav luag tag nrho tawm ntawm lub cev los ntawm ob lub raum. Kev nce qib ntawm creatinine qhia tau hais tias muaj kev ua haujlwm tsis zoo ntawm ib lossis lwm yam kabmob sab hauv.
Kev tshuaj xyuas biochemical yog qhov nkag tau yooj yim tshaj plaws thiab qhia txog kev kuaj ntshav. Nws yog ib qho tseem ceeb rau cov neeg mob uas pom tseeb cov tsos mob ntawm hypercreatininemia, urolithiasiskab mob, nrog rau kev puas tsuaj rau cov leeg pob txha, nrog rau cov muaj peev xwm pub raum. Txhawm rau kom cov ntaub ntawv ntawm qhov concentration ntawm creatinine tsis cuam tshuam, nws yog ib qho tsim nyog yuav tsum tsis suav nrog lub cev hnyav 48 teev ua ntej mus rau chav kuaj. Nyob rau yav tsaus ntuj ntawm kev kuaj ntshav, tso tseg cawv thiab dej qab zib uas muaj caffeinated, tsis txhob noj cov zaub mov muaj protein ntau. Nws yog qhov zoo tshaj rau kev xeem thaum sawv ntxov ntawm lub plab khoob.
Norm thiab pathology
Reference qhov tseem ceeb ntawm creatinine hauv cov ntshav nyob ntawm lub hnub nyoog, poj niam txiv neej, lub cev thiab kev nyiam ua noj ntawm tus neeg. Qhov concentration ntawm ib yam khoom yog txiav txim los ntawm tus kheej cov leeg nqaij, yog li nws qib hauv cov ntshav ntawm cov txiv neej feem ntau yog siab dua cov poj niam. Lub raum noj qab nyob zoo tawm mus txog 2 g ntawm creatinine ib hnub, yog li tiv thaiv kev qaug dab peg ntawm lub cev.
Cov kev txwv ntawm cov qauv hauv cov chaw kuaj mob sib txawv yuav txawv me ntsis ntawm qhov ntsuas qhov nruab nrab. Creatinine tsis yog qhov ntsuas bioindicator tshaj plaws ntawm lub raum, daim siab, lossis kab mob musculoskeletal. Txhawm rau kuaj pom hypercreatininemia thaum ntxov, nws raug nquahu kom pub ntshav ob zaug hauv ib xyoos.
Etiological yam
Lub cev ua rau cov ntshav siab creatinine suav nrog hormonal tsis ua haujlwm thaum cev xeeb tub, lactation, kev ua si lub cev hnyav, kev noj zaub mov tsis zoo, lossis kev noj zaub mov tshwj xeeb. Qee qhov xwm txheej, qib ntawm cov metabolite nce tsis yog vim qhov ntau ntawm nws cov khoom tsim tawm, tab sis vim qhov txo qis hauv cov ntshav plasma vim lub cev qhuav dej lossis ntshav poob. Thov nco ntsoov tias yog tias koj pub ntshav rau biochemistry thib obtav su, qhov tshwm sim yuav siab dua thaum sawv ntxov.
Hypercreatininemia feem ntau cuam tshuam nrog cov kab mob hauv qab no:
- Lub raum tsis ua haujlwm.
- Tshuaj lom, mob lossis mob cirrhotic ntawm daim siab.
- mob ntshav qab zib nephropathy.
- Hyperadrenal muaj nuj nqi.
- Kev raug mob rau cov leeg nqaij, pob txha.
- Cov tawv nqaij kub hnyiab.
- Acromegaly lossis gigantism.
Kev mob hluav taws xob lossis kab mob autoimmune xws li mob caj dab rheumatoid, myasthenia gravis, lupus erythematosus ua kom cov protein ntau. Cov tshuaj uas muaj cov nyhuv nephrotoxic, nrog rau cov khoom noj muaj protein ntau, nce ntshav creatinine. Txhawm rau ntsuas cov txiaj ntsig ntawm biochemical tsom xam kom raug, tus kws kho mob yuav tsum paub txhua yam xwm txheej thiab cov yam ntxwv ntawm tus neeg mob txoj kev ua neej.
Vim muaj peev xwm khaws cia siab ntawm lub raum thiab tsis txaus siab ntawm cov metabolite, kuaj ntshav ntxiv rau urea. Cov nitrogenous compound, nrog rau creatinine, qhia txog kev tsim khoom ntawm lub raum ua haujlwm. Kev nce hauv urea hauv cov ntshav tau hais thaum nws qib mus dhau qhov siab tshaj qhov tso cai (8.3 mmol / l).
daim duab kho mob
Creatinine yog ib qho tshuaj lom me ntsis, tab sis lub cev ua rau muaj kev sib txawv tseem ceeb ntawm cov qauv nrog mob taub hau, xeev siab, saj txawv txawv hauv qhov ncauj thiab lwm yam cim ntawm intoxication. Kev ua xyem xyav ntawm hypercreatininemia poob yog tias tus neeg mob yws yws ntawm edema, ua tsis taus pa,cov leeg tsis muaj zog, txo qis lossis nce hauv cov zis txhua hnub. Muaj cov ntshav siab poob qis, rub qhov mob hauv thaj tsam lumbar, thaum mob hnyav, tuaj yeem tshwm sim.
Kev kho mob
Tau txiav txim siab qhov xwm txheej ntawm tus kab mob thiab ua rau muaj creatinine ntau ntxiv hauv cov ntshav, xaiv cov kev kho mob uas tsim nyog. Yog li, yog tias tus neeg mob raug mob ntshav qab zib nephropathy, cov tshuaj hypoglycemic tau sau tseg. Kev kho mob yooj yim rau cov kab mob autoimmune suav nrog corticosteroids thiab tshuaj tiv thaiv kab mob. Lub raum tsis ua haujlwm yog kho nrog lub voj diuretics, uas ua kom cov zis tawm ntawm lub cev sai.
Qhov ncauj tau txais cov tshuaj hauv qab no thiab kev noj zaub mov kom txo qis cov ntshav metabolite:
- Ketosteril. Cov tshuaj muaj xws li ketone analogues ntawm amino acids, uas cuam tshuam rau glomerular pom tus nqi thiab txo cov synthesis ntawm nitrogenous compounds.
- YChitosan. Ib tug haib sorbent fights tsis tau tsuas yog nrog ntxiv phaus, nce creatinine, urea nyob rau hauv cov ntshav, tab sis kuj tiv thaiv kev loj hlob ntawm gout thiab osteoporosis. Chitosan muaj cov nyhuv analgesic, tswj pH tshuav nyiaj li cas hauv lub cev.
- Ntxiv nrog thioctic acid. Siv raws li ib tug anti-toxic thiab anti-inflammatory tus neeg sawv cev. Thioctic acid lossis vitamin N koom nrog hauv cov metabolism hauv lub zog, txo cov tshuaj insulin, thiab txhawb kev poob phaus.
NSAIDs, ACE inhibitors, tshuaj tua kab mob tetracycline, barbiturates thiab Cyclosporine tuaj yeem ua rau qhov hnyav dua.hypercreatininemia. Nco ntsoov xyuas nrog koj tus kws kho mob ua ntej noj cov tshuaj no.
Cov txheej txheem kho lub cev tuaj yeem txo tus neeg mob lub sijhawm rov zoo. Qhov cuam tshuam ntawm kev siv hluav taws xob qis qis rau ntawm thaj tsam lumbar txhim kho cov kev ua haujlwm ntawm lub raum thiab microcirculation ntawm cov leeg nqaij, txhawb nqa peripheral lymph txaus. Nrog rau kev nce creatinine hauv cov ntshav, ntxiv rau cov kev kho tseem ceeb, nws yuav tsis mob rau kev ua haujlwm ntawm kev zaws.
ntsuas ntsuas tseem ceeb
Lub raum tsis ua haujlwm kawg hauv lub raum tsis ua haujlwm, ua rau myositis dav dav, leptospirosis lossis lwm yam kab mob sib kis hnyav ua rau muaj mob hnyav hypercreatininemia (ntau tshaj li 100 mmol / l). Cov theem siab ntawm cov metabolite yog cov yam ntxwv ntawm kev ua txhaum ntawm secretory-excretory muaj nuj nqi ntawm lub raum, nqaij polytrauma.
Yog tias kev kho mob tsis zoo tsis tau txais txiaj ntsig zoo, lawv tig mus rau cov txheej txheem tshem tawm ntawm lub cev, tshwj xeeb, hemodialysis. Lub tom kawg yog ib qho ntxiv rau lub raum purification apparatus hu ua "artificial raum". Extracorporeal hemocorrection yog ua nyob rau hauv lub tsev kho mob, cov txheej txheem kav li ntawm 3 mus rau 4 teev. Txoj kev tso cai rau koj coj ib tug neeg tawm ntawm lub xeev tseem ceeb.
Kev noj haus
Yog tsis muaj cov vitamins, micro thiab macro ntsiab, kev sib koom ua haujlwm ntawm cov leeg nqaij, paj hlwb, tso zis thiab lwm yam hauv nruab nrog cev tsis tuaj yeem ua tau. Xws li complex carbohydrates, unsaturated fatty acids, txaustus nqi ntawm fiber ntau. Ua tib zoo saib xyuas cov dej haus: 1.5-2 litres ntawm cov dej uas tsis yog carbonated ib hnub twg tswj cov dej-ntsev sib npaug hauv lub cev.
Rau hypercreatininemia, txhawb koj cov zaub mov:
- txiv hmab txiv ntoo thiab zaub tshiab.
- khoom fermented mis nyuj.
- noj nqaij qaib los yog nqaij luav.
- zaub thiab txiv roj.
Thaum nws los txog rau kev noj zaub mov tsis muaj protein ntau nrog cov ntshav siab creatinine, nws txhais tau tias txwv tsis pub noj cov protein, tsis tshem tawm ntawm cov khoom noj. Proteins muab lub cev nrog lub zog, koom nrog hauv cov leeg nqaij, tsim cov tshuaj hormones, enzymes thiab cov tshuaj tiv thaiv. Yog li, qib siab ntawm creatinine hauv cov ntshav plasma tuaj yeem cuam tshuam nrog kev cuam tshuam ntawm kev poob phaus.
Muab cov zaub mov kib thiab ntsim, cov ncuav pastries tshiab, cov mis nyuj ntshiab, cov nqaij haus luam yeeb, khoom noj yooj yim thiab zaub mov ceev, tsis txhob tsim txom cov tshuaj yej dub, kas fes thiab cawv. Replenish qhov xav tau khoom qab zib nrog freshly squeezed kua txiv, zib mu. Xaiv rau steamed, ci txiv hmab txiv ntoo thiab zaub.
Recipes of traditional Medicine
Txhais tau raws li cov tshuaj diuretic thiab cov khoom noj khoom haus tau ua tiav dhau qhov kev sim ntawm lub sijhawm. Lawv yog cov pheej yig, yooj yim rau siv, tsis tshua muaj provoke kev loj hlob ntawm kev tsis haum tshuaj. Txhawm rau normalize qib ntawm creatinine, cov ntaub ntawv ua kua dej feem ntau yog siv: rho tawm, infusions, decoctions, thiab lwm yam.
Ntau txoj hauv kev zoo los tawm tsam hypercreatininemia:
- diuretic tshuaj yej. Cov nroj tsuag yog brewed nyias los yog sib tov nyob rau hauv sib npaug zos proportions; koj muaj peev xwm yuav npaj txhij-ua "lub raum" sau nyob rau hauv ib lub tsev muag tshuaj. Nettle nplooj mus zoo nrog calendula paj thiab knotweed, chamomile nrog mint, dill noob. Txoj kev kho mob rau siab creatinine hauv cov ntshav yog xaiv los ntawm tus kws kho mob ntawm tus kheej.
- noj tshais. Nyob rau yav tsaus ntuj, ncuav mov nrog dej txias, thaum sawv ntxov muab cov cereal o ntawm qis cua sov thiab boil me ntsis. Tsis txhob ntsev lub porridge thiab tsis season nrog butter. Rice ntxuav lub cev los ntawm creatinine thiab lwm yam khoom ntawm nitrogen metabolism yog tsim rau 14 hnub.
- Decoction of wild rose. Raws li cov ntsiab lus ntawm vitamin C, cov txiv hmab txiv ntoo ntawm tsob ntoo "overtook" txawm txiv qaub thiab dub currant berries. Cov dej haus zoo muaj diuretic thiab anti-inflammatory nyhuv, ntxuav cov hlab ntsha ntawm cov cholesterol. Txhawm rau npaj ib decoction, ncuav 2 tbsp. l., yav tas los qhuav thiab crushed txiv hmab txiv ntoo nrog boiling dej (400 ml). Nqa cov kua mus rau ib lub boil, tom qab 10 feeb tshem tawm ntawm lub qhov cub thiab lim los ntawm 2-3-txheej gauze los yog lim. Cov neeg mob uas muaj ntshav siab creatinine tau pom zoo kom haus ib decoction peb zaug hauv ib hnub, 0.25 khob ua ntej noj mov.
ntsuas kev tiv thaiv
Ua kom muaj ntau yam kev noj haus txhua hnub, ua kom zoo ntawm kev pw tsaug zog thiab tsaug zog. Thaum tsaus ntuj, kev hloov pauv ntawm creatine rau creatinine qeeb, cov txheej txheem metabolic nkag mus rau theem nquag tom qab noj tshais. Nyob rau hauv caum ntawm ib tug toned, embossed lub cevCov neeg ncaws pob feem ntau siv cov khoom siv hluavtaws (protein). Feem ntau cov kev noj zaub mov kom tau txais cov leeg nqaij khaws cov kua hauv lub cev, yog li ntawd, nce creatinine thiab urea hauv cov ntshav. Tswj cov ntshav siab ntsuas, vim hais tias nyob rau hauv cov ntshav siab, cov synthesis ntawm cov metabolite yog tsis tu ncua. Lub zog thiab kev ua kis las raug txwv nruj heev, kev thauj khoom yuav tsum tsis pub dhau lub peev xwm ntawm lub cev.
Summarize
Lub plawv ntawm tib neeg lub neej yog cov tshuaj biochemical nyuaj, tag nrho cov uas txiav txim siab peb tus kheej thiab theem ntawm lub cev noj qab haus huv. Kev nce me ntsis hauv cov ntshav creatinine hauv cov neeg laus thiab menyuam yaus tsis yog qhov ua rau muaj kev txhawj xeeb, tab sis yuav tsum tau rov kuaj dua. Cov tshuaj niaj hnub muaj kev paub txaus los tiv thaiv kev sib sau ntawm cov metabolite hauv cov ntshav plasma thiab ua kom nws siv los ntawm lub cev. Saib xyuas!
