Creatinine thiab urea hauv cov ntshav: tus qauv, yog vim li cas rau qhov nce, txiav txim siab ntawm qhov kev sim

Cov txheej txheem:

Creatinine thiab urea hauv cov ntshav: tus qauv, yog vim li cas rau qhov nce, txiav txim siab ntawm qhov kev sim
Creatinine thiab urea hauv cov ntshav: tus qauv, yog vim li cas rau qhov nce, txiav txim siab ntawm qhov kev sim

Video: Creatinine thiab urea hauv cov ntshav: tus qauv, yog vim li cas rau qhov nce, txiav txim siab ntawm qhov kev sim

Video: Creatinine thiab urea hauv cov ntshav: tus qauv, yog vim li cas rau qhov nce, txiav txim siab ntawm qhov kev sim
Video: [Hmong Vietsub] Kuv Puas Nyob Hauv Koj Lub Siab - (Laj Tsawb) 把你藏在我心里 - (邹兴兰) 2024, Kaum ib hlis
Anonim

Hauv ntau cov kab mob, thaum nws yuav tsum tau kuaj ntshav biochemical, ntawm cov ntsuas koj tuaj yeem pom creatinine thiab urea. Lawv cov txiaj ntsig rau feem ntau qhia txog lub xeev ntawm lub raum hauv tib neeg lub cev.

Ob qhov ntsuas yog cov khoom ntawm nitrogen metabolism. Raws li cov txiaj ntsig ntawm cov kev sim, nrog rau kev soj ntsuam, kev kuaj xyuas, thiab lwm yam kev kuaj mob, tus kws kho mob txiav txim siab txog kev ua haujlwm ntawm lub raum.

Definition

Urea yog qhov khoom kawg ntawm kev tawg ntawm cov protein molecules. Hauv daim siab, cov proteins ua ntej ua cov amino acids thiab tom qab ntawd mus rau hauv me me nitrogen tebchaw, uas yog tshuaj lom rau lub cev. Lawv yuav tsum tau muab tshem tawm. Rau qhov no, urea yog tsim los ntawm complex tshuaj tiv thaiv. Nws raug tshem tawm ntawm lub cev los ntawm kev lim cov ntshav hauv cov tubules ntawm lub raum.

Urea ntshav kuaj
Urea ntshav kuaj

Creatinine yog ib qho ntawm cov khoom kawg ntawm kev tawg ntawm creatine. Nws yog tsim nyob rau hauv daim siab thiab nkag mus rau cov leeg thiab lwm yam ntaub so ntswg, ncaj qha koom nyob rau hauv lub zog metabolism. Cov protein no muaj qee qhov kev hloov pauv thiab hloov pauvlub zog hauv lub cell ntawm nws cov qauv.

Creatinine tau tso tawm los ntawm ob lub raum thiab tsis nqus rov qab rau hauv cov ntshav. Cov cuab yeej no tau pom cov ntawv thov tshwj xeeb hauv kev kuaj mob.

Ntshav creatinine
Ntshav creatinine

Meaning

Creatinine thiab ntshav urea yog cov cim tseem ceeb ntawm lub raum noj qab haus huv. Txij li qee cov txheej txheem pathological tshwm sim hauv cov kabmob no cuam tshuam cov txheej txheem pom, cov kws kho mob tuaj yeem xav tias qee yam tsis raug nrog kev tshuaj xyuas yooj yim.

Kev kuaj xyuas los txiav txim siab qhov concentration ntawm cov protein metabolism hauv cov khoom no yog hais txog kev tshuaj ntsuam, uas yog, pawg. Thaum kuaj mob lossis nkag mus rau hauv tsev kho mob, kev tshuaj xyuas raug muab rau txhua tus. Qhov no yog qhov tsim nyog, ua ntej ntawm tag nrho cov, rau kev tshawb pom ntxov ntawm cov kab mob raum. Tsis tas li ntawd, nrog kev nce ntxiv ntawm creatinine thiab urea, txoj hauv kev kho mob yuav raug hloov me ntsis, cov tshuaj uas cuam tshuam rau ob lub raum yuav raug xaiv.

Nce hauv creatinine thiab urea
Nce hauv creatinine thiab urea

Norma

Nyob rau hauv txhua daim ntawv xeem, thiaj li hu ua tus nqi siv yog sau tawm tsam qee yam khoom. Qhov no yog qhov ntau ntawm cov nqi ib txwm muaj ntawm qhov no lossis qhov ntsuas ntawd.

Ua haujlwm hauv qhov concentration ntawm cov tshuaj nyob ntawm qhov piv ntawm cov txheej txheem ntawm lawv tsim thiab tawm. Los ntawm sab nraud ua rau, noj nqaij ntau dhau, ua kom lub cev muaj zog tuaj yeem cuam tshuam qhov tshwm sim.

Kev kuaj ntshav yog coj los ntawm cov hlab ntsha thaum sawv ntxov ntawm lub plab khoob, tom qab 8-14 teev ntawm kev yoo mov. Nyob rau yav sawv ntxov, nws yog qhov zoo dua kom tsis txhob muaj kev ntxhov siab thiab kev tawm dag zog lub cev ntau dhau. Cov tom kawg raug tso cai tsuas yog nrog kev tso cai ntawm tus kws kho mob thiabyog tias tsim nyog, xyuas cov haujlwm thaum lub sijhawm thauj khoom ntawd. Qhov no yog siv los ntawm cov kws ncaws pob kws tshaj lij.

Kev kuaj ntshav rau creatinine thiab urea tsom xam
Kev kuaj ntshav rau creatinine thiab urea tsom xam

Cov qauv ntawm creatinine thiab urea hauv cov ntshav tuaj yeem sib txawv. Rau urea, cov cim qhia tau zoo ib yam thiab sib npaug ntawm 2.5-8.3 mmol / l.

Creatinine muaj cov qauv sib txawv hauv qee pawg hnub nyoog. Cov menyuam mos yug tshiab muaj qhov muaj txiaj ntsig ntawm 27-88 µmol / l, cov menyuam yaus hnub nyoog qis dua 1 xyoos - 18-35, menyuam yaus hnub nyoog 1-12 xyoos - 27-62, cov hluas - 44 - 88, cov txiv neej laus - 62-132, poj niam - 44-97.

Txuag kev ua haujlwm

Kev txo qis hauv cov ntshav creatinine thiab urea, raws li txoj cai, tsis muaj nqi kuaj mob. Qhov kev hloov pauv hauv creatinine no tsis cuam tshuam los ntawm kev ua rau lub cev tsis zoo, tsis zoo li urea. Kev yoo mov, daim siab tsis ua haujlwm, txo qis hauv catabolism, uas yog, kev puas tsuaj, ntawm cov protein, nrog rau kev nce diuresis feem ntau ua rau nws txo qis.

Tab sis ntau zaus koj tuaj yeem pom qhov nce hauv urea thiab creatinine hauv kev tshuaj xyuas. Yog vim li cas feem ntau nyob rau hauv kab mob raum. Qhov no yuav sau hauv qab no.

nce ntshav creatinine

Qhov concentration ntawm ib yam khoom hauv cov ntshav ntawm cov neeg noj qab haus huv feem ntau yog tus nqi tas mus li thiab tsis tshua muaj nyob ntawm qhov ua rau extrarenal. Txo nws cov ntsiab lus tsis muaj qhov tseem ceeb hauv kev kho mob.

Creatinine Formula
Creatinine Formula

Yog tias kuaj pom qhov nce ntxiv, ces ua ntej lawv xav txog lub raum tsis ua haujlwm. Qhov kev kuaj mob no yog tsim thaum qib 200-500 µmol / l mus txog. Txawm li cas los xij, kev nce hauv creatinine thiab urea yog cov cim tom qab ntawm tus kab mob. Cov txiaj ntsig zoo li no tshwm sim thaum kwv yees li 50% ntawm lub raum tshuaj cuam tshuam.

Tsis tas li, qhov nce hauv creatinine tuaj yeem kuaj pom hauv ntshav qab zib mellitus, hyperthyroidism, plab hnyuv, leeg atrophy, gigantism, acromegaly, kev raug mob hnyav thiab kub hnyiab. Yog li ntawd, txhawm rau kuaj xyuas kom raug, nws yog ib qho tsim nyog yuav tsum tau kuaj xyuas tag nrho.

Kev hloov pauv hauv cov ntshav urea

Kev nce siab ntawm cov khoom tseem ceeb dua. Ntawm cov laj thawj, 3 pawg tau sib txawv:

  1. Adrenal yog tshwm sim los ntawm kev tsim cov nitrogen metabolism hauv lub cev. Cov laj thawj zoo li no suav nrog kev noj cov protein ntau heev, lub cev qhuav dej hnyav tshwm sim los ntawm ntuav lossis raws plab, cov txheej txheem mob hnyav hauv lub cev, uas tau nrog cov protein ntau ntxiv.
  2. Renal. Nyob rau hauv cov ntaub ntawv no, raws li ib tug tshwm sim ntawm cov txheej txheem pathological uas cuam tshuam rau lub cev, lub raum cov khoom lub luag hauj lwm rau pom tuag. Yog tias qhov haujlwm tseem ceeb no cuam tshuam, ces urea tseem nyob hauv cov ntshav, thiab nws qib maj mam nce. Cov kab mob ua rau muaj qhov tshwm sim xws li glomerulonephritis, pyelonephritis, nephrosclerosis, malignant arterial hypertension, amyloidosis, polycystic lossis tuberculosis ntawm lub raum. Hauv cov xwm txheej zoo li no, lub raum pub dawb thiab lub raum tsis zoo, lossis hemodialysis hauv lwm txoj kev, tuaj yeem pab tau.
  3. Subrenal, uas yog, tiv thaiv kev tawm. Yog hais tias ib yam khoom txaus ntshai tsis pom qhov tawm los ntawm txoj hlab zis, ces nws raug absorbed rov qab rau hauv.ntshav, nce concentration muaj. Qhov tshwm sim no yog tshwm sim los ntawm kev txhaws ntawm lub plab ntawm lub raum thiab cov ureter los yog compression los ntawm sab nraud, piv txwv li, pob zeb hauv lumen, adenoma, mob qog noj ntshav.
  4. Ntshav urea formula
    Ntshav urea formula

Transcript of analyses

Paub txog tus nqi ntawm urea thiab creatinine hauv cov ntshav ntshav, nrog rau qhov nce hauv cov ntsuas, ib tus tuaj yeem txiav txim siab txog qib ntawm lub raum tsis ua haujlwm. Nws yog ib qho tsim nyog xav txog qhov nthuav dav ntxiv ntawm kev muab qhab nia ntawm lub xeev no.

Cov qauv rau RFI yog:

  • serum creatinine qib 200-55 µmol / ml;
  • nce qib hauv nws qib los ntawm 45 µmol / ml ntawm tus nqi dhau los hauv qab 170 µmol / ml;
  • nce qhov ntsuas ntau dua 2 npaug piv rau qhov qub.

Tus mob hnyav AKI raug kuaj pom thaum kuaj pom muaj creatinine ntau dua 500 µmol / ml. Tab sis hauv kev xyaum ntawm tus kws kho mob, muaj cov txiaj ntsig siab dua 1000 µmol / ml.

mob raum
mob raum

Yog tias qhov kev tshuaj ntsuam tau pom tias qhov nce hauv urea ntau dua 10 mmol / l, qhov no ib txwm qhia tias lub raum puas, qhov no lawv kuj ua rau lub raum tsis ua haujlwm, thiab qhov nce ntawm creatinine thiab urea ib txwm sib koom tes. Nyob rau tib lub sijhawm, qhov concentration ntawm tom kawg hauv thaj tsam ntawm 6.5 - 10.0 mmol / l kuj tuaj yeem qhia lwm yam kab mob. Cov mob no ntawm cov neeg mob hauv kev kho mob hu ua uremia.

mus qhov twg?

Yog tus kws kho mob tau sau tshuaj rau creatinine thiab ntshav urea, ces tus neeg mob yuav tsum mus rau nws nrog cov txiaj ntsig. Yog tias muaj kev hloov pauv me me, lawv feem ntau yuav muabrov muab qhov kev tshuaj ntsuam xyuas, vim qhov yuam kev hauv kev suav tsis suav nrog.

Yog tias qhov kev xav tau hloov pauv ntau zaus lossis nce ntxiv, tus kws kho mob yuav xa tus neeg mob mus rau tus kws kho mob nephrologist, tus kws kho mob raum tshwj xeeb. Nws yuav txheeb xyuas qhov laj thawj ntawm qhov tshwm sim, ua qhov kev ntsuam xyuas ntxiv thiab sau cov kev kho mob uas tsim nyog, thiab muab cov lus pom zoo.

Pom zoo: