Myasthenia yog ib yam kab mob uas tshwm sim nws tus kheej hauv daim ntawv ntawm kev qaug zog thiab qaug zog ntawm cov leeg. Paralysis feem ntau tshwm sim vim cov leeg tsis muaj zog. Feem ntau, tus kab mob no cuam tshuam rau cov leeg ntawm lub qhov muag, lub ntsej muag, tus nplaig, daim di ncauj, caj pas, caj dab thiab lub caj pas. Tus kab mob no nquag mus zuj zus, yog li nws yuav tsum muaj lub tswv yim txog cov tsos mob thiab ua rau myasthenia gravis. Nws kuj yuav tsum tau txheeb xyuas sai li sai tau. Hauv qee tus neeg, nws pom meej meej nyob rau hauv kev tshwm sim sab nraud, tab sis nyob rau hauv txhua rooj plaub, yuav tsum muaj kev kuaj mob. Ib qho ntawm nws txoj hauv kev yog qhov kev sim prozerin.
Forms of myasthenia gravis
Ua ntej teb cov lus nug ntawm nws yog dab tsi, kev sim tshuaj proserine, koj yuav tsum piav qhia txog myasthenia gravis nws tus kheej. Muaj peb yam tseem ceeb ntawm tus kab mob no:
- YMyasthenia gravis. Yam ntxwv los ntawm kev puas tsuaj rau lub qhov muag cov leeg (tej zaum yuav tshwm sim rau cov txiv neej laus).
- Bulbar daim ntawv. Feem ntau nws yog kev txhim kho ntxiv ntawm qhov muag. Characterized los ntawm kev puas tsuaj rau pawg bulbarpaj hlwb (glossopharyngeal, hypoglossal).
- daim ntawv qhia dav dav. Nws yog kev sib xyaw ua ke ntawm cov tsos mob ntawm ob qho dhau los, tab sis nrog kev puas tsuaj rau cov leeg pob txha.
Yog li, nrog cov ntaub ntawv hauv zos (qhov muag thiab lub qhov muag), qhov tsis muaj zog ntawm cov leeg nqaij ib leeg tau pom, nrog rau daim ntawv dav dav, cov leeg ntawm lub cev lossis ceg tawv raug kev txom nyem.
Symptoms
Thawj kauj ruam los kuaj mob myasthenia gravis yog txhawm rau txheeb xyuas nws cov tsos mob. Qhov tseem ceeb tshaj plaws yog cov leeg nqaij qaug zog thaum muaj kev ntxhov siab ntev. Raws li txoj cai, tom qab ob peb teev so, cov leeg muaj zog rov qab los.
Daim ntawv teev cov tsos mob tshwj xeeb yog raws li hauv qab no:
- "Lub suab ploj" thaum hu.
- Teeb meem zom thiab nqos zaub mov.
- Npua thaum txav mus, feem ntau tsis khaus heev (taug kev, zuag).
- Dab pob ntseg.
Qhov phom sij ntawm myasthenia gravis nyob rau hauv qhov pom tseeb "ntev" ntawm cov tsos mob, uas feem ntau tib neeg tsis xyuam xim rau. Yog li ntawd, nyob rau hauv ntau zaus, myasthenia gravis tau kuaj pom thaum nws twb dhau los lawm. Yog li ntawd, kev qaug zog ntau dhau, cov leeg tsis muaj zog thiab tsis muaj zog yog cov cim qhia ntawm tus kab mob thiab xav tau kev kuaj xyuas kom paub meej lossis tsis lees paub qhov kev kuaj mob.
Myasthenic ntsoog
Yog li hauv cov tshuaj hu ua qhov pib tshwm sim ntawm cov leeg tsis muaj zog, feem ntau mus txog tuag tes tuag taw. Cov cim qhia ntawm kev kub ntxhov yog raws li nram no:
- ua pathawj zaug ntiav thiab nquag, tom qab tsis sib xws thiab tsis tshua muaj. Hauv qhov no, tus neeg mob raug ntes nrog kev ntxhov siab, thiab nws lub ntsej muag thawj zaug tig liab, tom qab ntawd xiav. Ua kom tiav ua pa raug ntes nrog qhov tshwm sim tuag yuav tshwm sim.
- Pulse sai thiab ntshav siab nce. Ces tus mem tes yuav tsis tshua muaj zog thiab tsis muaj zog, thiab ces thready.
- Tswv hws hnyav thiab qaub ncaug.
Thaum tsis muaj kev pabcuam raws sijhawm, kev tshaib plab oxygen thiab lub hlwb puas tuaj yeem tshwm sim.
Nws yog ib qho tseem ceeb heev kom paub qhov txawv ntawm qhov teeb meem myasthenic los ntawm ib qho cholinergic. Cov tom kawg zoo ib yam li myasthenic, tab sis tshwm sim vim kev siv tshuaj ntau dhau rau myasthenia gravis.
Ua rau kab mob
Txawm hais tias qhov tseeb tias cov tsos mob ntawm myasthenia gravis paub, qhov ua rau nws tshwm sim tsis tau tsim kom tiav. Faib congenital thiab kis tau myasthenia gravis. Paub txog kev sib xyaw ua ke ntawm tus kab mob no nrog pathologies ntawm lub caj pas thymus qhia txog kev koom tes ntawm lub cev hauv cov txheej txheem pathological. Tsis tas li ntawd, myasthenia gravis tau pom nyob rau hauv cov kab mob ntawm lub paj hlwb, mob qog noj ntshav, lub mis, zes qe menyuam, prostate.
Lub ntsiab lus ntawm pathology yog kev cuam tshuam ntawm kev sib txuas neuromuscular. Cov leeg yog teem rau hauv kev txav los ntawm cov hlab ntsha impulses, uas kis tau nrog kev pab los ntawm neurotransmitters. Thaum lub sij hawm myasthenia, cov tshuaj tiv thaiv yog tsim los thaiv los yog ua rau cov receptors rau cov neurotransmitters tseem ceeb. Yog li ntawd, cov paj hlwb tsawg dua mus txog cov leeg, uas ua rau tsis muaj zog.
Cov tshuaj tiv thaiv uas ua rau cov neurotransmitter receptors ua rau puas tsuajua kom muaj cov kab mob thymus (thymus caj pas).
Myasthenia gravis tuaj yeem ua rau muaj qhov tshwm sim hauv qab no:
- Nyob.
- Kab mob.
- Kev nyuaj siab.
- Tshuaj uas cuam tshuam rau kev ua haujlwm ntawm paj hlwb receptors.
Kev kuaj mob ntawm myasthenia gravis
Yog tias cov tsos mob saum toj no tshwm sim, koj yuav tsum sab laj nrog kws kho mob hlwb. Nws yuav ua qhov kev ntsuam xyuas, txheeb xyuas cov kev tsis txaus siab thiab cov cim qhia uas tuaj yeem tsis pom. Txawm li cas los xij, kev siv cov tshuaj proserine yog qhov tsim nyog, vim nws nyuaj rau txheeb xyuas tus kab mob nrog kev kuaj xyuas yooj yim.
Prozerin yog dab tsi, cov ntaub ntawv dav dav
"Prozerin" yog tshuaj hluavtaws. Thaum ua ntawv thov, nws txo qis lub plawv dhia, ua rau kom cov qog ua kua qaub (nqaij, sebaceous, hws, thiab lwm yam), constricts cov menyuam kawm ntawv, txo qhov siab ntawm lub qhov muag, tones cov leeg, ua rau bronchospasm. Nws yog siv tsis tau tsuas yog rau kev sim rau myasthenia gravis, tab sis kuj nyob rau hauv kev kho mob ntawm tus kab mob no. Thaum siv cov tshuaj kho mob, nws txhim kho kev ua haujlwm ntawm kev sib txuas neuromuscular. Hauv cov koob tshuaj loj, nws tuaj yeem ua rau muaj kev cuam tshuam ntawm lawv txoj haujlwm. Prozerin yog tsim nyob rau hauv ampoules rau kev kuaj, thiab nyob rau hauv 15 mg capsules rau kev tswj hwm. Muaj los ntawm kev sau ntawv.
Ua qauv
Txoj kev ntawm kev sim tshuaj proserin yog los qhia txog kev daws "Proserin" hauv qab ntawm daim tawv nqaij. Tom qab ntawd, tom qab 20-30 feeb, tus kws kho mob tshuaj xyuas tus neeg mob kom txiav txim siab qhov tshwm sim. Nyob rau hauv lub xub ntiag ntawm myasthenia gravis, nws cov tsos mob ploj tom qab txhaj tshuaj Prozerin. Yog tsis muaj teebmeem ces yeej hais li ntawdKev kuaj proserin yog qhov tsis zoo. Hauv qhov no, myasthenia tsis tuaj. Rau qhov kev sim, tsuas yog siv "Prozerin" hauv ampoules.
Cov txheej txheem no tsis tas yuav muaj cov cuab yeej tshwj xeeb lossis kev ua haujlwm nyuaj. Nws yog txaus kom muaj peev xwm muab ib qho yooj yim subcutaneous txhaj. Cov no yog cov kev cai tseem ceeb uas piav qhia meej txog yuav ua li cas rau kev xeem proserine.
Txoj kev siv tshuaj
Zoo ib yam tshuaj, Prozerin muaj nws tus kheej indications thiab contraindications.
Indications:
- YMyasthenia gravis.
- Paralysis
- Lub sijhawm rov qab los tom qab mob encephalitis, meningitis.
- Atrophy ntawm lub paj hlwb.
- Txoj kev mob ntawm lub zais zis thiab plab hnyuv.
- Normalization ntawm neuromuscular kev sib txuas.
Siv tau rau cov neeg laus thiab menyuam yaus.
Contraindications rau kev siv ntawm Prozerin yog:
- Hypersensitivity rau cov tshuaj nquag.
- Vagotomy.
- Kab mob ntawm cov hlab plawv.
- Asthma.
- Kab mob plab hnyuv.
- Kab mob ntawm cov kab mob genitourinary.
- YKev cev xeeb tub thiab lactation.
Yog li, txawm hais tias qhov kev sim prozerin rau myasthenia gravis yog cov cuab yeej kuaj mob, "Prozerin" nws tus kheej tuaj yeem siv los ua tshuaj. Nws yuav tsum tau muab sau tseg tias vim lub sij hawm luv luv ntawm cov nyhuv, rau kev kho mob ntawm myasthenia "Prozerin" tsuas yog siv ua ke nrog.lwm yam tshuaj.
Side effects
Cov kev mob tshwm sim ntawm cov tshuaj cuam tshuam rau ntau yam kabmob thiab lub cev ntawm tus neeg mob. Cov qauv ntawm kev phiv yog raws li nram no:
- plab hnyuv: ntuav, xeev siab, raws plab, nce flatulence.
- Nervous system: mob taub hau thiab kiv taub hau, qaug zog thiab tsaug zog, spasms thiab convulsions, qhov muag tsis pom kev, tremors thiab involuntary nqaij contractions.
- Cov kab mob plawv: plawv arrhythmias, plawv nres.
- Cov kab mob ua pa: ua tsis taus pa, bronchospasm, ua pa nres.
- Kev ua xua: khaus, pob khaus, anaphylactic shock.
- Lwm yam: tso zis ntau zaus, tawm hws ntau dhau.
Dab tsi tuaj yeem hloov cov qauv prozerin
Txawm tias txoj kev no zoo heev, muaj lwm tus. Ib daim ntawv teev npe ntawm lawv yog raws li hauv qab no:
- Electromyography. Paub tias yog qhov kev xeem txo qis. Nws yog ib qho kev ntsuas ntawm qhov ntim ntawm bioelectrical signals hauv cov leeg. Nws yog nqa tawm ua ntej thiab tom qab kuaj prozerin.
- Electroneurography. Tshawb xyuas qhov ceev ntawm kev sib kis ntawm cov paj hlwb mus rau synapse.
- Kev kuaj ntshav rau cov tshuaj tiv thaiv kab mob uas thaiv thiab ua rau cov neurotransmitter receptors puas tsuaj.
- Kawm txog cov genotype. Nws yog ua los kom paub meej lossis tsis lees paub qhov xwm txheej ntawm tus kabmob.
- Computed tomography ntawm thymus. Tso cai rau koj txheeb xyuas qhov hloov pauv ntawm nws qhov loj me.
Tsis tas li ntawd, muaj kev sim tshwj xeeb los pab txheeb xyuas tus kab mob. Lawv yog cov yooj yim heev thiabua hauv tsev. Ntawm no yog lawv:
- Koj yuav tsum qhib thiab kaw koj lub qhov ncauj sai sai. Rov ua cov kev txav no rau plaub caug vib nas this. Thaum tsis muaj myasthenia gravis, ib tug neeg tswj ua ib puas lossis ntau lub voj voog.
- Tuag koj nraub qaum, koj yuav tsum ua kom koj lub taub hau tsa ib feeb.
- Yuav tsum tau ua nees nkaum squats nrog ib lub amplitude.
- Koj yuav tsum tau nyem thiab rub cov txhuam kom sai. Rau myasthenia gravis, qhov kev tawm dag zog no tuaj yeem ua rau poob ntawm daim tawv muag.
YKev kho mob myasthenia gravis
Kev kho mob ntawm myasthenia gravis yog ua tsis tau. Kev kho mob raug txo kom tsim kom muaj kev ruaj ntseg rau tus neeg mob. Lub luag haujlwm tseem ceeb yog txhawm rau nce qib ntawm cov neurotransmitter acetylcholine, uas ua kom muaj kev sib kis ntawm cov hlab ntsha mus rau cov leeg. Cov tshuaj hauv qab no yog siv thaum kho:
- tshuaj Anticholinesterase. Qee lub sij hawm pom lub npe AHEP. Cov tshuaj no neutralize cholinesterase, uas ib txwm ua rau acetylcholine.
- Potassium npaj. Ua haujlwm ntev ntawm AHEP, txhim kho cov leeg nqaij.
- YCytostatics. Txo cov tshuaj tiv thaiv kab mob thiab cov kab mob tiv thaiv kab mob uas tsim tawm.
- Kev npaj tshuaj hormones. Txo cov tsos mob.
- Ntxiv mus, tus kws kho mob tuaj yeem sau tshuaj immunoglobulins, tshuaj tiv thaiv kab mob, tshuaj tiv thaiv kab mob.
Thaum muaj tus kab mob hnyav dua, plasmapheresis, Prozerin, thymus gamma irradiation, ntau cov npe ntawm cov tshuaj immunoglobulins.
Myasthenia gravis siv sijhawm ntev los kho. Rau txoj kev kho kom ua rau kev tshem tawm, qee cov tshuaj yuav tsum tau noj rau lub neej. Thaum kho, koj yuav tsum tau saib xyuas tas lintshav siab thiab ntshav qab zib.
Yog tias muaj thymus qog, phais tau ua.
Physiotherapy
Physiotherapy yog dav siv los kho myasthenia gravis. Nws lub hom phiaj tseem yog txhawm rau txhim kho kev sib txuas neuromuscular, normalize cov ntaub so ntswg noj zaub mov.
Kev kho mob myasthenia yog siv:
- kev txhawb zog tam sim no.
- Kev nqus cov tshuaj.
- Electrophoresis ntawm cov tshuaj (feem ntau prozerin).
- Electrostatic massage.
- Kev kho xim (siv los cuam tshuam lub hlwb).
- Regular massage.
Thaum lub sijhawm tshem tawm thiab thaum tsis muaj myasthenic crises, kev kho spa raug tso cai. Cov chaw so ntawm Crimea, Sochi yog qhov zoo tshaj plaws.
Ua ntej ua kev kho mob spa, koj yuav tsum xyuas kom meej tias tus neeg mob tsis muaj contraindications rau daim ntawv no.
Nws yuav tsum raug sau tseg tias tsis muaj ib txoj hauv kev kho lub cev tuaj yeem siv cais, cais tawm ntawm kev kho mob tseem ceeb.
Huab cua
Txawm hais tias muaj tus kab mob hnyav, myasthenia gravis tau haum rau lub neej zoo thiab muaj txiaj ntsig. Rau txoj kev kho kom ua tiav, kev ua raws cai nruj heev rau kev tswj hwm, uas muaj nyob rau hauv lub sijhawm noj cov tshuaj tsim nyog, yog qhov tsim nyog. Kev tsis ua raws li tsoomfwv tau hem nrog kev rov qab los ntawm kev tawm tsam, mus txog qhov yuav muaj kev kub ntxhov.
Pom tseeb kuj yog qhov tsis lees paub ntawm kev kho tus kheej. Thaum thawj cov cim qhia ntawm myasthenia gravis tshwm sim, koj yuav tsum mus ntsib kws kho mob tam sim ntawd!
Kev Tiv Thaiv
Yog tus neeg raug kuaj mob"myasthenia gravis", nws yog contraindicated nyob rau hauv hnyav lub cev exertion thiab ntev raug rau lub hnub. Cov zaub mov yuav tsum muaj calorie tsawg. Nws yog ib qho tsim nyog yuav tau noj tshuaj ob qho tib si ncaj qha tawm tsam myasthenia gravis thiab txhawb kev tiv thaiv kab mob (cov tshuaj tiv thaiv kev tiv thaiv tsuas yog pom zoo thaum lub sij hawm tshem tawm). Antipsychotics, diuretics, tranquilizers thiab qee pawg tshuaj tua kab mob yog contraindicated.
Daim ntawv zoo tshaj plaws ntawm kev tiv thaiv myasthenia gravis, zoo li lwm yam kab mob, yog saib xyuas koj txoj kev noj qab haus huv. Nco ntsoov: tsis muaj teeb meem koj yuav tsum tau noj tshuaj rau tus kheej, thiab yog tias koj muaj teeb meem kev noj qab haus huv, koj yuav tsum mus ntsib kws kho mob tam sim ntawd!
Zoo kawg
Vim qhov tsis pom tseeb ntawm cov tsos mob thiab ua rau myasthenia gravis, ceev thiab siv tau zoo rau kev kuaj mob no yuav tsum tau ua. Tsis tas li ntawd, thaum kuaj pom, txoj kev kho nyuaj yog tsim nyog. Prozerin test yog qhov ceev tshaj plaws, yooj yim tshaj plaws thiab txhim khu kev qha tshaj plaws los kuaj xyuas myasthenia gravis. "Prozerin" nws tus kheej yog ib qho tseem ceeb ntawm txoj kev kho mob ntawm tus kab mob.
