Uterine adenocarcinoma: theem, kho, prognosis

Cov txheej txheem:

Uterine adenocarcinoma: theem, kho, prognosis
Uterine adenocarcinoma: theem, kho, prognosis

Video: Uterine adenocarcinoma: theem, kho, prognosis

Video: Uterine adenocarcinoma: theem, kho, prognosis
Video: mus de tshuaj zoo mob qog noj ntshav(cancer..) 2024, Kaum ib hlis
Anonim

txheej txheem Oncological ua rau muaj kev loj hlob ntawm malignant neoplasms nyob rau hauv cov poj niam cev xeeb tub yog hu ua uterine adenocarcinoma. Nws feature yog hloov nyob rau hauv lub endometrium, lub sab sauv txheej ntawm lub tsev menyuam. Ib lub qog tsim los ntawm cov hlwb txawv txav ntawm cov qog nqaij hlav thaum pib ntawm txoj kev loj hlob yog tsim thaum tsis muaj cov cim qhia.

tus qog no yog dab tsi?

Piv rau cov qog nqaij hlav qog nqaij hlav uas tshwm sim los ntawm cov leeg nqaij, adenocarcinoma ntawm lub ncauj tsev menyuam yog ib yam ntawm cov qog nqaij hlav malignant neoplasms. Pawg pheej hmoo rau tus mob no suav nrog cov poj niam uas tau hla qhov pib ntawm plaub caug xyoo thiab cov uas muaj hnub nyoog tsis tshaj rau caum-tsib xyoo. Tam sim no, muaj kev nyiam ua rau muaj qhov tshwm sim ntawm qhov mob ntawm hom qog no, nrog rau kev ua kom rov zoo ntawm cov kab mob. Kwv yees li ib nrab ntawm txhua tus neeg mob yog cov poj niam uas muaj hnub nyoog me nyuam.

uterine adenocarcinoma
uterine adenocarcinoma

Nyob rau theem pib, cov neoplasm tsis phemkho tau, tab sis tus txheej txheem txuas ntxiv txhim kho, qhov kev pheej hmoo loj zuj zus tuaj.

Txhua yam no ua rau muaj kev kuaj mob tsis tu ncua thiab kev ceeb toom ntawm cov kws kho mob tshwj xeeb cuam tshuam txog hom kab mob oncology.

Vim txoj kev loj hlob

Tam sim no, nws yog qhov nyuaj heev rau cov tshuaj niaj hnub los tsim kom muaj tseeb ua rau tsim ntawm uterine adenocarcinoma. Tab sis cov xwm txheej uas ua rau muaj kev loj hlob ntawm cov qog tau raug txheeb xyuas los ntawm cov kws tshaj lij.

Hom mob qog noj ntshav no yog nyob ntawm cov tshuaj hormones. Yog li ntawd, nyob rau hauv kev cuam tshuam ntawm steroid poj niam txiv neej cov tshuaj hormones, glandular cov ntaub so ntswg ntawm lub endometrium hloov cyclically. Raws li kev cuam tshuam ntawm cov tshuaj estrogen, cov ntaub so ntswg pib sib faib ntau heev thiab qhov tshwm sim ntawm neoplasms nce ntau.

Tsis tas li, kev hloov pauv hormonal xws li pib lig thaum cev xeeb tub thiab pib thaum ntxov ntawm cev xeeb tub, mob qog nqaij hlav hauv lub mis yav dhau los, kev cuam tshuam hauv cov kab mob endocrine, kev kho tshuaj mus sij hawm ntev, polycystic zes qe menyuam, ntshav qab zib mellitus tuaj yeem ua rau muaj kev pheej hmoo.

Kev tsis muaj menyuam, cev xeeb tub thiab lub neej kev sib deev tuaj yeem ua rau muaj mob qog noj ntshav. Yog hais tias ib tug poj niam muaj feem cuam tshuam ncaj qha rau tus neeg mob uas muaj mob qog noj ntshav hauv plab, ces nws kuj mus rau hauv pab pawg muaj kev pheej hmoo.

Tus kab mob no tuaj yeem tshwm sim hauv cov neeg uas tsim txom cov khoom noj ceev, muaj tus cwj pwm tsis zoo, muaj kev phom sij lossis ua haujlwm tsis zoo.

theem ntawm uterine adenocarcinoma

Thaum pib ntawm cov txheej txheem oncological, qog hlwb txav los ntawm cov mucous daim nyias nyias mus rau phab ntsa ntawm lub cev. Yog tias nyob rau theem no tus kab mob no tau kuaj pom thiab kho kom raug, ces qhov kev lav phib xaub ntawm kev ua tiav ntawm tus kab mob tshwm sim hauv yuav luag txhua kis.

adenocarcinoma ntawm lub ncauj tsev menyuam
adenocarcinoma ntawm lub ncauj tsev menyuam

theem tom ntej ntawm hom mob qog noj ntshav no yog suav nrog cov qog nqaij hlav qog nqaij hlav hauv cheeb tsam tsev menyuam. Tab sis lawv tseem tsis tau dhau mus rau cov kabmob uas nyob ze. Kev kho tau zoo nyob rau theem no yog qhov muaj txiaj ntsig zoo, thiab kev rov ua tiav tiav tiav hauv ntau dua xya caum feem pua ntawm cov neeg mob.

Thaum kuaj pom cov theem tom ntej ntawm kev loj hlob ntawm cov qog nqaij hlav, qhov txhab kis mus rau cov qog ntshav thiab cov kabmob uas nyob ib sab. Txawm li cas los xij, txawm li cas los xij, ntau tshaj li ib nrab ntawm cov neeg mob uas tau kuaj pom tus mob uterine adenocarcinoma muaj txoj hauv kev kom rov qab ua tiav ntawm tus kab mob.

theem kawg ntawm kev loj hlob ntawm cov qog nqaij hlav malignant tsis tsuas yog cuam tshuam rau cov kabmob uas nyob ze, tab sis kuj ua rau kis tau tus kabmob metastases. Tsawg tshaj li peb caug feem pua ntawm cov neeg mob los ntawm hom mob qog noj ntshav no tuaj yeem tshem tau nws tag nrho.

Lub sijhawm tsis zoo hauv lub neej yog kev tshawb pom ntawm uterine adenocarcinoma hauv tus neeg mob. Qhov kev kwv yees ntawm no yuav ncaj qha nyob ntawm theem ntawm tus kab mob.

Kev faib tawm

mob qog noj ntshav endometrial muaj peb hom uas nyob ntawm kev faib cell.

Ib yam ntawm cov txheej txheem xws li kev sib txawv ntawm adenocarcinoma ntawm lub tsev menyuam yog kev loj hlob ntawm cov qog nqaij hlav hauv lub epithelium. Ntawm no, cov kab mob malignant tseem muaj qhov sib txawv me ntsis ntawm cov neeg noj qab haus huv. Tab sis lawv cov nuclei tau hloov pauv thiab tau txais cov duab elongated, nrog rau qhov loj me. Cov txheej txheem oncological kis superficially mus rau hauv cheeb tsam myometrial. Thiab kev txhim kho ntawm cov teeb meem thiab kev tsim ntawm kev loj hlob hauv cov qog ntshav nyob ntawm nws qhov chaw.

Tam sim no, tsis muaj qhov tshwm sim tsis zoo, cov xwm txheej no tsis suav tias yog qhov txaus ntshai, tab sis nws nyuaj heev los txheeb xyuas qhov teeb meem thiab kuaj mob.

Thaum kuaj pom qhov sib txawv nruab nrab ntawm lub tsev menyuam adenocarcinoma, muaj ntau lub hlwb hloov pauv, thiab qib ntawm lawv cov polymorphism siab dua. Nrog rau qhov zoo sib xws ntawm cov chav kawm nrog hom tau piav qhia saum toj no, muaj qhov ua tau zoo dua ntawm cov teeb meem thiab qhov pib ntawm metastasis.

Ua ke nrog cov kua dej ntws, cov qog hlwb kis thoob plaws lub cev. Qhov yuav tshwm sim ntawm metastases tshwm sim me me, tab sis qee zaus lawv tseem tuaj yeem tshwm sim.

Txoj hauj lwm tseem ceeb tshaj plaws nyob rau theem no yog kev txheeb xyuas tus kab mob raws sij hawm thiab kho tam sim ntawd.

Kev sib txawv ntawm uterine adenocarcinoma yog ib qho kev sib xyaw ntawm cov hlwb loj thiab cov kab tsis sib xws. Ntawm no, cov ntaub so ntswg uas tau hloov pauv pathological tshwm sim, thiab cov hlwb tau tshaj tawm tias polymorphism. Qhov tseem ceeb ua rau muaj kev pheej hmoo ntawm metastases. Yog li ntawd, lub caij nyoog kom tshem tau tus kab mob nyob rau theem no tsis yog siab heev.

mob qog noj ntshav ntau tshaj

mob plab plab
mob plab plab

Endometrioid adenocarcinoma ntawm lub tsev menyuam yog tus cwj pwm los ntawm kev muaj cov qog nqaij hlav uas muaj cov tubular zoo thiab muaj ib lossis ntau txheej ntawm mutated.hlwb. Yog li ntawd, cov ntaub so ntswg atypia pib. Feem ntau qhov no pathology tau pom nyob rau hauv cov poj niam uas mob qog noj ntshav uterine. Stimulation ntawm estrogen, nrog rau thickening thiab loj hlob ntawm lub endometrium, yuav provoke qhov tsos ntawm no malignant tsim.

Daim ntawv serous ntawm hom mob qog noj ntshav no suav tias yog qhov mob hnyav tshaj plaws. Feem ntau, nrog rau cov qog loj hlob zoo li no, metastases thaum ntxov tau pom nyob rau hauv daim nyias nyias ntawm lub plab kab noj hniav.

Yeej, hom malignancy no tshwm sim hauv cov poj niam tom qab lub cev tsis muaj zog. Nyob rau hauv kev sib piv, secretory adenocarcinoma ntawm lub tsev menyuam muaj ntau tsawg, qhov kev tshwm sim ntawm qhov zoo heev.

Tseem tsim nyog sau cia yog qhov tseeb cell carcinoma. Vim lub fact tias nws provokes lub tsos ntawm implantation thaum ntxov metastasis nyob rau hauv lub serous daim nyias nyias ntawm lub plab kab noj hniav, prognosis ntawm daim ntawv no yog heev unfavorable.

Type los ntawm qog qhov chaw

Tus kab mob malignant uas tshwm sim feem ntau hauv cov hlwb squamous ntawm lub epithelium ntawm sab hauv ntawm lub ncauj tsev menyuam yog adenocarcinoma ntawm lub ncauj tsev menyuam.

Nws tuaj yeem txhim kho ob sab hauv qhov chaw mos (exophytic daim ntawv) thiab tob rau hauv cov kwj dej ntawm caj dab ntawm tus poj niam lub cev (daim ntawv endophytic).

Hom mob qog noj ntshav no tsis muaj cov tsos mob tshwm sim thiab tsis xis nyob, uas ua rau nws txaus ntshai heev. Yog li ntawd, txhawm rau txhawm rau txhawm rau tshawb pom cov qog no, nws yuav tsum tau mus ntsib kws kho mob tsis tu ncua.

qhov chaw ntawm uterine adenocarcinoma
qhov chaw ntawm uterine adenocarcinoma

Adenocarcinoma ntawm lub tsev menyuam lub cev tsim nyob rau hauv txhua daim nyias nyias ntawm lub cev. CovTus kab mob yog nyob ntawm cov tshuaj hormones thiab rhiab heev rau cov teebmeem ntawm estrogen. Lub zos ntawm hom oncology nyob rau hauv ib nrab ntawm cov mob yog lub fundus ntawm lub tsev menyuam, thiab lub yeej ntawm lub isthmus thiab los yog tag nrho cov kab noj hniav yog tsis tshua muaj.

Nrog rau kev loj hlob ntxiv ntawm cov qog nqaij hlav, cov hlwb hloov pauv, vim qhov tshwm sim ntawm thaj chaw cuam tshuam nce, thiab cov metastases npog tag nrho cov kev ua me nyuam thiab lwm yam kabmob ntawm tus neeg mob.

Muaj mob qog noj ntshav no feem ntau yog kev sib deev ncaj ncees ua ntej pib lub cev tsis muaj zog. Kev kuaj mob histological ntawm kev khawb ntawm lub ncauj tsev menyuam yuav pab kom pom qhov neoplasm. Nws yog ib qho nyuaj heev rau kev kuaj mob ntawm cov qog tshwm sim hauv cov ntaub so ntswg sib sib zog nqus.

Symptoms

Raws li txoj cai, adenocarcinoma ntawm endometrium ntawm lub tsev menyuam ua rau nws tus kheej tsuas yog tom qab ua tiav thawj theem ntawm cov txheej txheem oncological tom qab swb ntawm lub ncauj tsev menyuam. Tus neeg mob tsim cov dej tsis muaj xim, uas tom qab ntawd ua ntshav. Hauv cov poj niam uas muaj hnub nyoog yug me nyuam, kev loj hlob ntawm qog nqaij hlav provokes hnyav thiab ntev kev coj khaub ncaws thiab los ntshav ntawm lawv. Thiab qhov kev xav rov qab los ntawm lub voj voog nyob rau hauv cov neeg mob uas muaj hnub nyoog postclimatic yuav tsum ua rau muaj kev mus ntsib tus kws kho mob sai.

Raws li cov txheej txheem oncological txhim kho, lub plab nce hauv cov poj niam, thiab mob tshwm sim hauv nws qhov qis thiab sab nraub qaum. Cov kev xav zoo ib yam tshwm sim tom qab kev sib deev. Kev pw tsaug zog yog cuam tshuam, lub cev kub nce mus rau qhov tsis muaj laj thawj, thiab qaug zog thiab chim siab nce.

Ib qog nqaij hlav tawm sab nraum lub tsev menyuam ua raumob nyob rau hauv perineum, aggravated los ntawm tso zis, kev sib deev thiab plob tsis so tswj. Ntshav tom qab kev sib deev tshwj xeeb tshaj yog hais tau.

metastases ntawm uterine adenocarcinoma
metastases ntawm uterine adenocarcinoma

Kev kuaj pom tus kab mob malignant neoplasm

Kev kuaj mob thawj zaug yog kev tshuaj xyuas. Adenocarcinoma ntawm lub tsev menyuam yog kuaj pom los ntawm tus kws kho mob thaum palpation. Tom qab no, kev kuaj xyuas ntxiv yog tsim nyog. Qhov yooj yim tshaj plaws ntawm cov no yog aspiration biopsy. Ntawm tus neeg mob sab nraud, nws tuaj yeem ua tau ntau zaus, tab sis nyob rau hauv thawj theem nws yuav tsis muab cov txiaj ntsig. Txawm hais tias muaj kev tshawb fawb ntau dua, qhov tshwm sim ntawm kev tshawb nrhiav pathology ntawm thawj theem yog tsawg dua ib nrab ntawm cov xwm txheej.

Txoj kev ntsuas ntsuas ntsuas raws li kev kuaj ultrasound ntawm lub plab hnyuv siab raum tso cai rau koj txhawm rau kuaj pom cov phab ntsa loj ntawm lub tsev menyuam, thiab kuaj pom metastases thaum ntxov.

Uterine curettage yog ua rau kev kuaj cytological.

Txog hnub tim, txoj hauv kev zoo tshaj plaws rau kev kawm hom oncology no yog hysteroscopy thiab endometrial biopsy. Thaum tus txheej txheem biopsy, ib qho cuab yeej tshwj xeeb hu ua hysteroscope yog muab tso rau. Cov cuab yeej kho qhov muag no tso cai rau koj kuaj xyuas los ntawm sab hauv thiab nqa cov khoom sib cais kom pom lossis tsis hloov cov hlwb hauv lawv.

Kev kho mob

Cov kws tshaj lij xaiv cov kev kho mob rau uterine adenocarcinoma nyob ntawm theem ntawm malignant neoplasm thiab nws daim ntawv, nrog rau lub hnub nyoog ntawm tus neeg mob, muaj cov kab mob sib kis thiab metastases. Nyob rau tib lub sijhawm, tsis tshua muajKev tiv thaiv lub cev tsis tshua muaj. Lawv tuaj yeem tshwm sim tsuas yog thaum ntxov tshaj plaws ntawm cov qog loj hlob hauv cov poj niam uas tsis muaj menyuam.

Nyob rau hauv thawj theem (thawj thiab thib ob), nws raug nquahu kom ua qhov kev phais mob (hysterectomy) thiab tshem tawm lub tsev menyuam tag, thiab, yog tias qhia, cov ntaub so ntswg thiab cov qog nqaij hlav.

Tom qab siv txoj kev kho no, cov txheej txheem rov qab ua raws li, lub sijhawm uas nyob ntawm tus neeg mob thiab nws tus yam ntxwv. Thawj ob peb hnub, cov poj niam muaj kev qaug zog thiab qaug zog, tsis xis nyob thiab mob. Qee zaum cem quav thiab mob zais zis tuaj yeem tshwm sim. Tab sis cov kev xav no yog ib ntus. Lawv ploj mus nrog rau qhov maj mam rov qab los ntawm lub cev.

Tom qab ua haujlwm ntawm uterine adenocarcinoma, hormonal keeb kwm hloov pauv thiab qib ntawm poj niam cov tshuaj hormones txo qis. Yog li ntawd, kub flashes thiab hmo ntuj tawm hws, nrog rau qhov chaw mos dryness, tuaj yeem tshwm sim. Kev ua kom zoo ntawm cov tshuaj hormonal tshwm sim nrog kev pab ntawm cov tshuaj tshwj xeeb.

Radiotherapy yog siv los ua kev npaj ua ntej thiab hauv lub sijhawm tom qab phais. Nrog kev pab ntawm X-rays uas cuam tshuam rau qee qhov chaw ntawm lub tsev menyuam, cov qog hlwb raug rhuav tshem thiab lawv txoj kev loj hlob ntxiv raug tso tseg. Ua ntej siv txoj kev no, nws yog ib qho tsim nyog yuav tau tshem tawm cov kab mob sib kis. Tom qab tag nrho, tom qab nws, lub cev tsis muaj zog yuav tsis tuaj yeem tua cov kab mob thiab cov kab mob. Qhov tsis zoo ntawm txoj kev no yog anemia thiabthrombocytopenia.

Cov qog nqaij hlav cancer kuj tuaj yeem tuag nrog kev kho tshuaj khomob thiab kho tshuaj hormone. Cov tshuaj tshwj xeeb tau nkag mus rau hauv lub cev thiab kho cov keeb kwm hormonal, txo qhov kev pheej hmoo ntawm kev rov ua dua ntawm uterine adenocarcinoma. Kuj tseem muaj tshuaj muaj los tiv thaiv qee yam mob qog noj ntshav.

Nws tsim nyog sib tham txog cov tshuaj ib txwm siv nrog tus kws tshaj lij. Tab sis nws yog qhov tsim nyog los siv lawv ua qhov tseem ceeb.

Kev kuaj mob ntawm uterine adenocarcinoma
Kev kuaj mob ntawm uterine adenocarcinoma

Tiv thaiv thiab huab cua

Txhawm rau tiv thaiv hom mob qog noj ntshav no, kev kuaj xyuas tsis tu ncua los ntawm kws kho mob yog qhov tsim nyog. Kev saib xyuas tshwj xeeb yuav tsum tau them rau cov neeg sawv cev ntawm kev sib deev tsis muaj zog, uas muaj kev pheej hmoo. Koj yuav tsum tau tshem tawm cov kab mob inflammatory thiab precancerous raws sij hawm, tsis txhob muaj kev sib raug zoo xws li kev sib deev thiab coj lub neej kev sib deev nrog ib tug, pov thawj tus khub.

Nws tseem yuav tsum tau saib xyuas koj cov qib hormonal, yug menyuam kom raws sijhawm thiab zam kev sib cuag nrog cov carcinogens. Qhov tseem ceeb sib npaug yog txoj kev ua neej noj qab haus huv thiab tswj lub cev qhov hnyav.

Qhov kev pom zoo tshaj plaws yog pom nyob rau lub sijhawm thaum ntxov ntawm kev loj hlob ntawm cov qog nqaij hlav oncological. Lawv tuaj yeem raug tshem tawm nrog kev pab ntawm kev phais thiab kev kho tom ntej. Cov kev kho mob zoo li no tsis hnyav heev, thiab tom qab ib xyoos tom qab tus neeg mob tuaj yeem rov ua lub neej zoo li qub.

Muaj ntau yam teeb meem tos cov poj niam uas muaj qog nqaij hlav qog nqaij hlav hauv theem thib ob. Yog vim li cas txoj haujlwm ua haujlwmntawm no ntau, lub sij hawm rov qab los ua ntev thiab nrog rau kev siv hluav taws xob thiab tshuaj tua kab mob. Yog li ntawd, lub peev xwm los dais cov me nyuam ploj mus ib txhis thiab muaj zog hormonal tsis txaus tshwm sim, thiab cov chav kawm kho mob ncua mus txog peb xyoos. Tab sis txawm nws tsis mus txog lub xeev ua ntej tus kab mob. Txawm li cas los xij, lub neej hauv cov theem no tseem nyob hauv feem ntau.

theem tom ntej yog qhov hnyav dua los ntawm qhov tseeb tias ntxiv rau lub tsev menyuam hnyav hnyav, qhov chaw mos lossis ib feem ntawm nws kuj raug tshem tawm. Kev rov zoo tag nrho ntawm no yog ua tsis tau txawm tias tom qab peb xyoos ntawm kev kho. Tab sis qhov ciaj sia taus ntawm theem no yog los ntawm kaum mus rau rau caum feem pua. Nyob rau theem kawg, tsuas yog lub neej ntawm tus neeg mob yuav cuam tshuam. Qhov tshwm sim ntau tshaj plaws ntawm kev tuag muaj nyob rau theem no.

mob qog noj ntshav
mob qog noj ntshav

Txhua yam kev ntsuas los kho lub cev muaj qhov txiaj ntsig zoo, tab sis tom qab lub neej tseem yuav cuam tshuam nrog ntau qhov hnyav.

Tab sis tsis txhob poob rau hauv kev poob siab thaum kuaj pom mob qog noj ntshav. Cov tshuaj niaj hnub tso cai rau koj los kuaj xyuas nws nyob rau lub sijhawm thiab tshem tawm ntawm cov kab mob malignant. Qhov tseem ceeb ntawm no yog tsis saib xyuas kev noj qab haus huv thiab tsis txhob ncua kev kho mob, tshwj xeeb tshaj yog thaum suav txhua hli.

Pom zoo: