Lipoic acid (vitamin N) yog ib yam khoom zoo ib yam li cov vitamins. Nws nthuav feature yog nws solubility nyob rau hauv dej thiab rog, uas feem ntau txiav txim siab nws cov hauj lwm thiab daim ntawv thov. Nws yog tsim los ntawm lub cev me me thiab muaj nyob hauv qee yam khoom noj. Nws yog ib qho muaj zog antioxidant uas tiv thaiv thiab thim rov qab kev puas tsuaj los ntawm cov dawb radicals. Koom tes hauv cov metabolism ntawm cov khoom noj uas siv, pab hloov lawv mus rau hauv lub zog.
Keeb Kwm
Alpha Lipoic Acid (ALA), tseem hu ua thioctic acid, octolipene thiab vitamin N, yog yim-carbon organic compound belongs rau tsev neeg carboxylic acid thiab fatty acid subfamily. Thaum pib, qhov sib xyaw tau suav tias yog cov vitamin, tab sis qhov kev ntseeg no tau hloov pauv thaum nws pom tias cov khoom sib xyaw ua ke hauv tib neeg lub cev.
Thioctic acid muaj qhov tshwj xeeb antioxidant peev xwm. Tsis zoo li lwm cov tshuaj antioxidants (xws li vitamin C lossis E), nws yog dej soluble thiab rog soluble. Cov cuab yeej no, nyob rau hauv lem, txhais tau hais tias cov teebmeem ntawm nws qhov kev ua yog pom yuav luag thoob plaws hauv lub cev. Lub peev xwm los tshem tawm cov dawb radicals txiav txim siab qhov tseem ceeb ntawm ALA nyob rau hauv cov txheej txheem metabolic, vim tias qhov nruab nrab ntawm cov reactive molecules no yog ib txoj hauv kev zoo heev ntawm kev ua kom detoxification thiab pab tswj kev ua haujlwm hauv homeostasis. Tsis tas li ntawd, qhov sib xyaw no yog cofactor rau cov enzymes koom nrog hauv kev hloov cov zaub mov noj rau hauv lub zog. Nws cov dej num sib npaug muab ib theem txaus ntawm qhov tseem ceeb.
Alpha-lipoic acid (vitamin N) tuaj yeem ua ke hauv lub cev, tab sis tsuas yog nyob rau hauv qhov txwv kom txaus kom txaus siab rau cov txheej txheem metabolic hauv theem pib. Yog li ntawd, nws yog ib qho tsim nyog yuav tau muab cov khoom noj los ntawm sab nraud. Los ntawm kev ntxiv cov vitamins nrog lipoic acid thiab ncav cuag ntau tshaj ntawm cov tshuaj no hauv lub cev, nws muaj peev xwm ua kom nws muaj peev xwm ua kom muaj zog antioxidant. Vim li no, ALA tau dav siv los tiv thaiv ntau yam kab mob, xws li paj hlwb, nrog rau cov kab mob uas tshwm sim los ntawm kev ua haujlwm tsis zoo ntawm cov hlab ntsha. Cov tshuaj no kuj tseem ceeb heev rau kev ua haujlwm ntawm daim siab, vim nws tiv thaiv kev rog thiab yog ib qho tshuaj tiv thaiv kab mob cancer zoo.
khoom
Alpha-lipoic acid (vitamin N) tuaj yeem nkag rau lub cev nrog zaub mov. Nws qhov chaw nplua nuj tshaj plaws yognqaij liab (lub plawv, raum, siab). Nws tau kwv yees tias qhov concentration ntawm ALA hauv cov khoom no yog nyob rau nruab nrab ntawm 1 mus rau 3 micrograms ib 1 gram ntawm cov khoom qhuav. Ib qho kev daws teeb meem zoo los ua kom nws cov concentration hauv lub cev kuj tseem suav nrog cov zaub hauv cov zaub mov. Nws yog qhov zoo tshaj plaws los xaiv cov zaub ntsuab - spinach, broccoli, Brussels sprouts, peas thiab txiv lws suav. ALA tseem muaj nyob rau hauv cov poov xab Saccharomyces cerevisiae, uas yog ib hom kab mob tshwj xeeb siv los ua npias, vim li cas cov lipoic acid (vitamin N) tuaj yeem pom hauv cov dej no.
ALA thiab cov kab mob neurodegenerative
Ua tsaug rau nws cov khoom antioxidant, ALA yog ib qho txiaj ntsig zoo ntawm kev tiv thaiv kev loj hlob ntawm ntau yam kab mob loj. Tom qab kev tshawb fawb, nws tau raug pov thawj tias cov tshuaj no tiv thaiv cov ntaub so ntswg ntawm lub hlwb los ntawm reactive molecules, xws li cov khoom tsim thaum muaj protein ntau glycation, thiab los ntawm dawb radicals. Yog li ntawd, cov kua qaub no tiv thaiv Alzheimer's kab mob, thaum lub sij hawm tsim thiab cov proteins uas phem hu ua beta-amyloid accumulates nyob rau hauv lub hlwb. Nws ntxiv txo qhov mob tshwm sim los ntawm lawv lub xub ntiag.
Lipoic acid (vitamin N) tiv thaiv kev tuag ntawm tes hauv thaj chaw ntawm lub hlwb cuam tshuam los ntawm tus kab mob Parkinson. Thaum lub sijhawm muaj tus kabmob, ALA yuav tsum tau noj nrog rau lwm cov as-ham, xws li, piv txwv li, acetyl L-carnitine, phosphatidylserine, lossis docosahexaenoic acid, txhawm rau kom nce ntxiv.kev ua tau zoo ntawm kev tiv thaiv kev txawj ntse thiab kev paub tsis meej.
Hauv cov neeg mob uas muaj Alzheimer's lossis Parkinson's kab mob, mitochondrial tsis ua haujlwm ntawm cov paj hlwb tshwm sim. Kev siv ALA ua tau zoo txo qhov kev loj hlob ntawm cov kab mob los ntawm kev txo qis oxidative kev nyuaj siab hauv cov hlwb.
ALA thiab kab mob plawv
Nrog nws cov tshuaj tiv thaiv kab mob antioxidant thiab tiv thaiv kab mob, nrog rau nws txoj haujlwm los tswj lub cev lipid profile, vitamin N (lipoic acid) yog tus neeg sawv cev zoo hauv kev txo qis kev pheej hmoo ntawm kev tsim cov kab mob ntawm cov hlab ntsha. Cov nyhuv ntawm ALA feem ntau yog los tiv thaiv cov txheej txheem endothelial hauv cov phab ntsa ntawm cov hlab ntsha, nrog rau kev so cov hlab ntsha. Yog li, cov tshuaj no tswj cov ntshav siab, txhim kho cov ntshav khiav thiab tiv thaiv kab mob xws li mob plawv lossis mob stroke. Los ntawm kev txhim kho cov ntshav mus rau hauv nruab nrog cev thiab txhua qhov ntawm lub cev, cov kua qaub no tuaj yeem siv tau zoo los txo qhov mob, piv txwv li, nyob rau hauv qis qis tom qab taug kev ntev lossis kev cob qhia hnyav.
Hauv kev tswj hwm cov ntshav lipid profile, thioctic acid yog qhov tseem ceeb tshwj xeeb thaum txo qis cov roj cholesterol, tshwj xeeb tshaj yog nws cov teeb meem LDL feem, uas yog, cov lipoproteins tsawg. Kev noj tshuaj ntxiv ntawm cov tshuaj no ua rau txo qis ntawm cov atherosclerotic plaques tsim, tiv thaiv cov hlab ntsha nqaim.
Kev siv cov thioctic acid kuj tau pom tias muaj txiaj ntsigrau cov neeg uas muaj ntau yam kab mob los yog mob plawv. Cov txiaj ntsig tau qhia tias ALA tiv thaiv kev tuag ntawm lub plawv, uas tuaj yeem tshwm sim, piv txwv li, nyob rau hauv cov ntshav qab zib siab.
ALA thiab ntshav qab zib
Kev siv ALA hauv kev kho mob ntshav qab zib tau raug pov thawj los muab cov txiaj ntsig ntsuas tau, tshwj xeeb tshaj yog txo qis kev pheej hmoo ntawm inflammatory thiab oxidative hloov, uas feem ntau tshwm sim los ntawm cov piam thaj ntau dhau hauv lub cev. Tsis tas li ntawd, los ntawm kev noj tshuaj ntxiv nrog cov tshuaj no, koj tuaj yeem ua rau lub cev rhiab heev rau insulin thiab qabzib zoo heev. Kev siv ALA tso cai rau koj tswj hwm qhov sib npaug ntawm carbohydrates hauv cov ntshav. Nyob rau hauv lem, tiv thaiv cov endothelium hauv ob sab phlu ntawm cov hlab ntsha tso cai rau lipoic acid tiv thaiv vascular ntshav qab zib thiab kab mob raum.
Cov neeg mob ntshav qab zib feem ntau tsim lwm yam mob hu ua ntshav qab zib neuropathy. Nws yog manifested los ntawm ib tug muaj zog kev xav ntawm qhov mob thiab kub hnyiab nyob rau hauv lub caj dab, thiab nyob rau hauv ib tug tom qab theem, thaum qhov mob me ntsis, kev puas tsuaj rau cov hlab ntsha thiab paj hlwb tshwm sim. Tom qab cov kev hloov pauv no, qhib qhov txhab thiab kis kab mob tuaj yeem tshwm sim, uas thaum kawg ua rau kev txiav tawm. Raws li kev ntsuam xyuas tau ua tiav, nws tau pom tias ALA, vim nws cov nyhuv antioxidant muaj zog, txo qhov kev pheej hmoo ntawm kev puas tsuaj rau cov paj hlwb thiab txhim kho cov ntshav khiav hauv cov neeg mob ntshav qab zib. Yog li ntawd, nws tuaj yeem siv tau zoo rau kev tiv thaivntshav qab zib neuropathy.
ALA thiab rog
Kev tshawb fawb qhia tias ALA cuam tshuam rau qee thaj chaw ntawm lub hlwb, yog li txwv kev qab los noj mov. Cov tshuaj tiv thaiv kev rog rog los ntawm kev ua kom cov metabolism thiab ua kom lub zog siv zog, ua rau kom muaj calorie ntau ntau. ALA txo cov roj uas tsim thiab khaws cia hauv daim siab. Tsis tas li ntawd, cov khoom no nce lub cev rhiab heev rau insulin thiab txhawb kev nqus cov piam thaj los ntawm cov ntshav kom normalize tag nrho cov carbohydrate profile.
Raws li kev tshuaj xyuas, cov vitamins nrog lipoic acid yog qhov xav tau zoo ntawm cov neeg ncaws pob. Vim yog cov cuab yeej ntawm kev tsim cov ATP thiab ua kom lub sijhawm rov ua dua tshiab, lub cev ntawm cov neeg nquag tuaj yeem tiv taus ntau dua kev tawm dag zog lossis kev ua si lub cev.
Tiv Thaiv Kab Mob
ALA tuaj yeem siv los tiv thaiv thiab kho mob qog noj ntshav. Hauv ntau qhov kev sim tshuaj ywj pheej, cov tshuaj no tau pom tias yuav tsum nres lub voj voog ntawm cov qog nqaij hlav qog noj ntshav thiab ua rau qeeb lossis nres cov qog loj hlob. Tsis tas li ntawd, qhov sib xyaw ua ke tuaj yeem ua rau cov txheej txheem ntawm apoptosis, lossis programmed cell tuag, uas yog lub cev tiv thaiv lub cev kom tshem tawm cov qog nqaij hlav ntawm nws. Nws kuj tau pom tias tiv thaiv cov khoom siv caj ces los ntawm kev hloov pauv uas ua rau muaj kev hloov pauv carcinogenic. Cov tshuaj no tuaj yeem tiv thaiv kev tsim ntawm metastases, vim tias nws txo qis kev ua haujlwm ntawm cov enzymes uas cov qog tawm tsam cov ntaub so ntswg ib puag ncig. ALAUa tsaug rau nws cov khoom antioxidant, nws tuaj yeem tshem tawm cov kev mob tshwm sim ntawm kev kho mob.
ALA thiab siab
Alpha-lipoic acid nce qib cysteine hauv lub cev. Lub tom kawg, nyob rau hauv lem, yog siv nyob rau hauv lub synthesis ntawm glutathione, uas yog ib tug ntawm cov haib tshaj compounds nrog antioxidant kev ua si, koom nyob rau hauv feem ntau ntawm lub cev detoxification hloov pauv uas tshwm sim nyob rau hauv daim siab. Lub luag haujlwm ntawm glutathione yog tshem tawm cov khoom lag luam metabolic uas tsim los ntawm cov dawb radicals lossis co toxins. Yog li, nws tiv thaiv hepatocytes los ntawm oxidative puas tsuaj thiab yog li tiv thaiv kab mob loj. 75 cov neeg uas raug lom los ntawm toadstools koom nrog hauv ib qho ntawm cov kev tshawb fawb. Lawv tau muab alpha lipoic acid thiab 67 ntawm 75 tau tshaj tawm tias tau zoo lawm.
Cov hlau hnyav hnyav hnyav hauv daim siab. Lawv excretion feem ntau nyuaj, thiab ntau dhau lawv tuaj yeem ua rau muaj kev cuam tshuam ntawm kev ua haujlwm ntawm lub cev thiab kev tuag. ALA tau pom tias muaj lub peev xwm tshwj xeeb rau chelate hlau kom lawv tuaj yeem raug tshem tawm ntawm lub cev zoo.
Lipoic acid - compatibility nrog cov vitamins
ALA ua raws li antioxidant tab sis tsis hloov vitamin C lossis E, cov antioxidants muaj zog tshaj ntawm cov vitamins. Vitamin N ua haujlwm nrog lawv los kho lawv cov antioxidant zog. Lipoic acid thiab vitamin E thiab C hauv kev sib xyaw ua ke muaj txiaj ntsig zoo hauv kev tawm tsam dawb radicals.
ALA muaj qhov zoo sib xws rau cov vitamins B, yog li nws ua haujlwm zoo nrog lawv, tshwj xeeb nrogThiamine (B1).
ALA feem ntau yog siv rau hauv cov tshuaj tiv thaiv kab mob ntshav qab zib nrog rau cinnamon. Kev sib xyaw ua ke muaj txiaj ntsig zoo rau cov neeg muaj ntshav qab zib ntau, vim nws pab tswj cov qib qabzib ib txwm muaj thiab txo qis cov tshuaj noj ntshav qab zib.
Kev sib xyaw ntawm silymarin, selenium thiab ALA yog siv los kho tus kab mob siab viral, vim nws pab tiv thaiv kev kis tus kab mob mus rau cirrhosis.
Lipoic acid: cov lus qhia vitamin
Rau kev tiv thaiv, koj tuaj yeem siv tshuaj noj nrog ALA chav kawm ntawm 10 mus rau 30 hnub. Lub sijhawm zoo tshaj plaws los coj lawv yog thaum sawv ntxov lossis yav tsaus ntuj, rau cov neeg koom nrog kev ua kis las - tam sim tom qab kev cob qhia.
Raws li cov lus qhia rau cov vitamins nrog lipoic acid, tus qauv noj txhua hnub ntawm ALA nyob ntawm 300-600 mg. Cov nyiaj no qee zaum tsim nyog muab faib ua ob qhov sib npaug. Vim tias qhov sib xyaw no tau yooj yim soluble hauv dej thiab roj, nws yuav tsum tau noj ua ntej lossis tom qab noj mov kom nws muaj bioavailability.
Contraindications thiab phiv
Lipoic acid yog suav tias yog cov tshuaj muaj kev nyab xeeb, kev siv uas tsis cuam tshuam qhov tshwm sim tsis zoo. Muaj tsawg zaus, tsuas yog cov tawv nqaij hloov pauv tuaj yeem tshwm sim, uas feem ntau ploj thaum cov tshuaj raug tso tseg.
Vim cov ntaub ntawv tsis txaus ntawm kev nyab xeeb ntawm ALA hauv cov poj niam cev xeeb tub thiab lactating, tsis pom zoo siv rau hauv cov xwm txheej no. Cov neeg mob ntshav qab zib yuav tsum kuaj nrog lawv tus kws kho mob ua ntej noj ALA, vim tias qhov sib xyaw no, nrog rau cov tshuaj ntshav qab zib, tuaj yeem txo cov ntshav qab zib ntau heev.
Kev quav cawv ua rau txo qis ntawm thiamine (vitamin B1) hauv lub cev. Kev siv alpha lipoic acid nrog qhov tsis txaus ntawm cov vitamin no tuaj yeem ua rau muaj ntau yam teeb meem kev noj qab haus huv. Nyob rau hauv cov ntaub ntawv ntawm vitamin B tsis txaus, lipoic acid yuav tsum tau ua ke nrog ib txhij noj cov vitamin B complex.
YVitamins "Complivit"
Cov khoom noj khoom haus no muaj cov khoom xyaw uas muaj txiaj ntsig zoo rau kev ua haujlwm ntawm lub cev. Kev sib xyaw ua ke ntawm cov vitamins nrog lipoic acid hauv Complivit pab tswj kev ua kom zoo, kev noj qab haus huv thiab lub cev ntawm tus neeg.
Cov tshuaj no yog ib qho ntawm cov nyiaj siv nyiaj vitamin complexes ntawm Lavxias teb sab tsim. Ib pob (60 ntsiav tshuaj) raug nqi txog 200-250 rubles. hauv khw muag tshuaj. Kev tshuaj xyuas ntawm Complivit vitamins nrog lipoic acid yog qhov zoo heev. Raws li cov neeg siv khoom, tom qab ib chav kawm ntawm kev noj cov tshuaj, kev noj qab haus huv, cov tsos ntawm daim tawv nqaij, plaub hau thiab cov rau tes pom tau zoo.
