Dab tsi yog tshuaj zoo li "Ganaton"? Qhov kev kho no pab tau li cas? Koj yuav pom cov lus teb rau cov lus nug no hauv kab lus no. Koj tseem yuav kawm txog cov neeg mob xav li cas txog cov tshuaj no, seb nws puas muaj contraindications, thiab nws yuav tsum tau noj li cas.
Daim ntawv ntawm cov tshuaj, nws ntim, muaj pes tsawg leeg, piav qhia
Cov tshuaj "Ganaton" ua li cas? Cov lus qhia, kev tshuaj xyuas hais tias cov cuab yeej zoo li no tuaj yeem yuav hauv daim ntawv ntawm cov ntsiav tshuaj uas yog dawb, plhaub (zaj duab xis), puag ncig, kos "HC 803" ntawm ib sab thiab muaj kev pheej hmoo ntawm lwm qhov.
Cov khoom xyaw nquag hauv cov tshuaj hauv nqe lus nug yog itopride hydrochloride. Raws li cov khoom pabcuam, cov tshuaj no suav nrog lactose, carmellose, pob kws hmoov txhuv nplej siab, anhydrous silicic acid, macrogol 6000, magnesium stearate, titanium dioxide, hypromellose thiab carnauba wax..
Cov ntsiav tshuaj zoo li no tau muag hauv cov pob hlwv, uas, dhau los, tau ntim rau hauv cov pob ntawv.
Yuav ua li cas cov tshuaj ua haujlwm
Ganaton yog dab tsi? Dab tsi pab tau cov tshuaj no? Nws yog siv rau lub hom phiajnce motility thiab lub suab ntawm lub plab zom mov.
Cov khoom xyaw nquag hauv cov khoom no yog itopride hydrochloride. Cov tshuaj no tshwj xeeb cuam tshuam rau sab sauv ntawm lub plab zom mov, thiab tseem ua rau kom tshem tawm cov zaub mov ntawm lub plab. Nws tseem yuav tsum tau muab sau tseg tias cov khoom nyob rau hauv nqe lus nug yog muaj peev xwm muaj ib tug antiemetic nyhuv.
Drug properties
Dab tsi yog qhov zoo tshaj plaws ntawm cov cuab yeej xws li "Ganaton"? Los ntawm qhov nws pab tau, peb yuav qhia ntxiv.
Cov tshuaj hauv nqe lus nug yog ib qho stimulator ntawm kev tso tawm ntawm acetylcholine. Nws cov khoom tseem ceeb activates gastric motility (propulsion). Qhov no tshwm sim vim kev tawm tsam nrog dopamine D2 receptors, nrog rau kev siv tshuaj tiv thaiv ntawm acetylcholinesterase kev ua haujlwm.
Itopride hydrochloride activates tso tawm acetylcholine thiab inhibits nws puas tsuaj.
Kinetic nta ntawm cov tshuaj
Qhov nqus ntawm cov tshuaj zoo li "Ganaton" nyob qhov twg? Cov lus qhia rau kev siv, tshuaj xyuas hais tias cov khoom xyaw nquag ntawm cov tshuaj no sai heev thiab yuav luag tag nrho absorbed los ntawm txoj hnyuv. Nws cov txheeb ze bioavailability yog kwv yees li 60%. Qhov no yog vim cov metabolism hauv cov tshuaj, uas tshwm sim thaum thawj zaug dhau los ntawm lub siab. Kev noj zaub mov tsis cuam tshuam rau bioavailability ntawm cov khoom.
Tom qab noj (qhov ncauj) 50 mg ntawm itopride hydrochloride, nws qhov siab tshaj plaws concentration tau mus txog tom qab 0.5-0.75 teev thiab yog li ntawm 0.28 mcg / ml. Rov ua duanoj cov tshuaj ntawm ib koob ntawm 50-200 mg peb zaug ib hnub twg rau ib lub lim tiam ua rau linear pharmacokinetics. Hauv qhov no, qhov sib sau tsawg kawg nkaus.
Kev sib txuas lus ntawm cov tshuaj nrog cov ntshav plasma protein yog kwv yees li 96%. Nws yog nquag faib nyob rau hauv tag nrho cov ntaub so ntswg, thiab kuj muaj nyob rau hauv siab concentrations nyob rau hauv daim siab, ob lub raum, qog adrenal, hnyuv me thiab plab. Cov tshuaj nkag mus los ntawm BBB hauv me me. Nws kuj tau tawm hauv cov kua mis.
Itopride hydrochloride thiab nws cov derivatives raug tso tawm hauv cov zis. Lub raum excretion ntawm active tshuaj tom qab ib koob tshuaj nyob rau hauv kev kho mob yog hais txog 75%. Lub davhlau ya nyob twg ib nrab-lub neej ntawm tus neeg sawv cev no yog kwv yees li rau teev.
Ganaton tshuaj: pab tau dab tsi?
Cov tshuaj no nquag siv los kho cov teeb meem plab hnyuv uas cuam tshuam nrog kev ua haujlwm tsis ua haujlwm dyspepsia (xws li mob plab), nrog rau kev mob plab qeeb.
Yog li cas cov tshuaj "Ganaton" yuav tsum siv? Kev siv cov cuab yeej no tau pom thaum:
- anorexia;
- bloating;
- siab kub;
- ntua;
- xav kom puv plab tom qab noj mov;
- mob lossis tsis xis nyob hauv thaj tsam epigastric;
- nausea.
txwv tsis pub noj tshuaj
Tam sim no koj paub dab tsi yog qhov zoo tshaj plaws ntawm cov cuab yeej xws li Ganaton. Yam tshuaj no kho li cas, peb kuj pom. Nws yuav tsum tau sau tseg tshwj xeebtias cov tshuaj hauv nqe lus nug yog contraindicated rau:
- cev xeeb tub;
- gastrointestinal los ntshav, mechanical obstruction lossis perforation ntawm gastrointestinal ib ntsuj av;
- hnub nyoog qis dua 16;
- pub mis niam;
- Hypersensitivity rau itopride los yog lwm yam auxiliary ingredient ntawm cov tshuaj.
Kev siv yeeb tshuaj zoo
Cov tshuaj no yog siv nrog ceev faj rau cov neeg laus vim qhov txo qis hauv lub raum thiab lub siab ua haujlwm, nrog rau muaj cov kab mob sib kis lossis lwm yam kev kho mob.
Vim qhov kev ua tau zoo ntawm acetylcholine, cov tshuaj hauv nqe lus nug tau pom zoo nrog kev ceev faj rau cov neeg mob uas qhov kev loj hlob ntawm cholinergic phiv tuaj yeem ua rau mob hnyav zuj zus ntxiv.
Yuav ua li cas coj Ganaton?
Cov ntsiav tshuaj uas nug yuav tsum tau noj ua ntej noj mov. Lawv ntxuav nrog dej dawb.
Cov tshuaj tsis muaj kev cuam tshuam rau tus neeg lub peev xwm tsav tsheb, nrog rau cov txheej txheem nyuaj. Thaum siv Ganaton los ntawm cov neeg laus lossis cov neeg uas muaj lub raum tsis zoo thiab lub siab ua haujlwm, lawv yuav tsum tau saib xyuas kev kho mob tas li.
Qee lub sij hawm tus kws kho mob yuav tsum tau kho cov tshuaj uas pom zoo. Nyob rau hauv cov ntaub ntawv ntawm kev huam yuaj ntawm cov tshuaj ntau, cov qauv ntsuas xws li kev kho mob thiab gastric lavage yuav tsum tau.
Tus neeg mob yuav tsum noj tshuaj "Ganaton" npaum li cas?Kev siv (kev tshuaj xyuas txog cov tshuaj tau tham hauv qab no) ntawm qhov kev kho no yuav tsum tau ua tsuas yog tom qab sab laj nrog kws kho mob. Qhov koob tshuaj txhua hnub ntawm cov tshuaj hauv nqe lus nug rau cov neeg laus yog 150 mg. Yog tias tsim nyog, qhov qhia kom muaj nuj nqis tuaj yeem hloov pauv los ntawm tus kws tshaj lij.
Raws li txoj cai, cov tshuaj no tau pom zoo kom noj peb zaug hauv ib hnub, ib ntsiav tshuaj ua ntej noj mov (50 mg). Lub sijhawm kho yog txiav txim los ntawm tus kws kho mob thiab tuaj yeem kwv yees li 5-8 lub lis piam.
Side actions
Cov tshuaj "Ganaton" tuaj yeem ua rau muaj kev phiv dab tsi? Cov tshuaj no pab nrog ntau yam kab mob ntawm lub plab zom mov, txawm li cas los xij, nws tuaj yeem ua rau muaj qhov tshwm sim tsis zoo hauv qab no:
- Endocrine system: gynecomastia, nce qib prolactin.
- YHematopoietic system: thrombocytopenia, leukopenia.
- Cov tshuaj tsis haum: tawv nqaij khaus, tawv nqaij hyperemia, anaphylaxis, ua pob.
- CNS: mob taub hau, kiv taub hau, tshee.
- plab hnyuv: jaundice, raws plab, nce salivation, cem quav, xeev siab, mob plab.
- Hloov pauv hauv kev kuaj sim: nce qib ntawm bilirubin thiab alkaline phosphatase, nrog rau kev ua haujlwm ntawm ALT, AST thiab GGT.
Drug interaction
Metabolic cuam tshuam nrog cov tshuaj no tsis tau. Qhov no yog vim qhov tseeb tias itopride yog metabolized tsis nyob rau hauv kev cuam tshuam ntawm isoenzymes ntawm cytochrome P450 system, tab sis nyob rau hauv qhov kev txiav txim ntawm flavin monooxygenase.
Cov tshuaj nquag ntawm cov tshuaj hauv nqe lus nug txhim khogastric motility, uas yuav cuam tshuam rau kev nqus ntawm lwm cov tshuaj noj qhov ncauj. Kev ceev faj yuav tsum tau saib xyuas thaum noj cov tshuaj nrog qhov ntsuas qis qis. Tib yam siv rau kev npaj nrog cov txheej txheej enteric thiab kev tso tawm ntawm cov khoom tseem ceeb.
Thaum Ganaton tau ua ke nrog Diazepam, Warfarin, ticlopidine hydrochloride, diclofenac sodium, nicardipine hydrochloride thiab Nifedipine, tsis muaj kev hloov pauv hauv kev khi ntawm itopride rau cov ntshav plasma proteins.
tshuaj tiv thaiv kab mob xws li Ranitidine, Cimetidine, Cetraxate thiab Teprenon tsis cuam tshuam rau kinetics ntawm itopride.
Cov tshuaj Anticholinergic ua rau tsis muaj zog ntawm cov tshuaj nquag hauv nqe lus nug.
Pub mis thiab cev xeeb tub
Tam sim no, tsis muaj cov ntaub ntawv txaus ntawm kev siv itopride hydrochloride thaum cev xeeb tub. Kev siv cov tshuaj no thaum cev xeeb tub yog ua tau tsuas yog thaum tsis muaj lwm txoj kev kho, nrog rau cov txiaj ntsig zoo rau leej niam, uas ntau dua qhov kev pheej hmoo rau tus menyuam hauv plab.
Nws tseem yuav tsum tau sau tseg tias tawm tsam keeb kwm yav dhau los ntawm kev siv cov tshuaj no, muaj kev pheej hmoo ntawm kev mob tshwm sim hauv tus menyuam mos. Hauv qhov no, yog tias tsim nyog siv tshuaj thaum pub niam mis, lactation yuav tsum tau nres.
Zoo tshuaj thiab nqi tshuaj
Koj puas paub cov tshuaj uas peb tab tom txiav txim siab nqi npaum li cas? Yog tias koj tsis muaj cov ntaub ntawv zoo li noyog tias koj muaj nws, peb yuav muab rau koj. Tus nqi ntawm cov khoom no nyob ntawm qhov cim-up ntawm lub network cov khoom pab thawj zaug thiab yog kwv yees li 250 rubles rau 10 ntsiav tshuaj.
Yog tias tsis pom cov tshuaj nrog lub npe no, ces nws tuaj yeem hloov nrog cov tshuaj analogue. Xws li cov tshuaj muaj xws li cov khoom uas muaj tib yam active tshuaj, uas yog, nrog itopride. Raws li lawv feem ntau siv "Itomed", "Itoprid", "Itopra" thiab "Primer"
Kev tshuaj xyuas los ntawm cov neeg mob thiab cov kws kho mob tshwj xeeb
Puas Ganaton pab nrog Helicobacter pylori? Cov kws tshaj lij tau tshaj tawm tias cov tshuaj hauv nqe lus nug yog cov tshuaj uas txhim kho lub suab nrov thiab kev txav ntawm lub plab zom mov. Qhov no tsis yog tshuaj tua kab mob uas tuaj yeem tua cov kab mob hais saum toj no. Txawm li cas los xij, qee zaum nws tseem raug tshuaj rau tus kab mob no, tab sis tsuas yog hauv kev kho mob ua ke nrog tshuaj tua kab mob thiab lwm yam tshuaj tiv thaiv kab mob.
Yuav luag txhua tus neeg mob uas tau siv tshuaj hauv nqe lus nug hais txog nws cov txiaj ntsig zoo. Raws li lawv, tom qab ua tiav chav kawm ntawm kev kho mob, cov tshuaj no tshem tawm tag nrho cov kev xav ntawm xeev siab thiab tsis xis nyob hauv thaj av epigastric, nrog rau hnyav thiab mob hauv plab.
Qee tus neeg mob hais tau zoo ntawm cov tshuaj no yog ib yam tshuaj rau kev kho mob ntawm lub plawv thiab ntuav.
Raws li cov lus ceeb toom ntawm kev tsis zoo ntawm Ganaton, lawv tsis tshua muaj. Raws li txoj cai, thaum noj cov tshuaj no, qee cov neeg mob tau nce salivation, tsaug zog lossis kiv taub hau.
Kev tshuaj xyuas cov xwm txheej ntawm kev noj tshuaj ntau dhau ntawm cov tshuaj no tsis tau sau tseg txog tam sim no. Tus nqi ntawm cov tshuaj zoo li Ganaton tau pom los ntawm cov neeg siv khoom tau txais lossis siab.
