"Ketoanalogues ntawm cov amino acids" - ib yam tshuaj uas pab kho cov protein-zog sib npaug. Cov ntsiav tshuaj yog siv rau hauv lub raum tsis ua haujlwm los txo BUN thiab creatinine. Cov khoom lag luam ua kom tau txais cov khoom siv tseem ceeb hauv lub cev nrog qhov tsawg kawg nkaus ntawm nitrogen.
"Keto analogs ntawm amino acids" yog dab tsi?
Hauv kev tshuaj, muaj ib pab pawg uas suav nrog cov proteins thiab amino acids. Cov tom kawg yog cov txheej txheem ntawm cov ntaub so ntswg tshwj xeeb. Thiab qee cov organic acids, xws li glutamic, aspartic, glycine yog neurotransmitters.
Tus neeg noj qab haus huv xav tau 70 g ntawm cov protein ib hnub. Nyob rau hauv ib tug xov tooj ntawm pathological tej yam kev mob, niaj hnub xav tau enzymes nce. Txhawm rau tswj lub neej ib txwm, siv cov proteins thiab cov amino acids sib xyaw ua ke. Parenteral kev tswj hwm ntawm cov proteins tuaj yeem ua rau muaj kev cuam tshuam anaphylactic. Kev sib xyaw ntawm tus kheej cov amino acids yog siv los tiv thaiv cov teebmeem tsis zoo. Lawv muab cov khoom noj khoom haus tiav tsis muaj kev kawm.tshuaj tiv thaiv kab mob hauv lub cev.
"Ketoanalogues ntawm amino acids" yog kev npaj ua ke, uas suav nrog kev hloov pauv rau cov organic tebchaw uas nws cov metabolites tuaj yeem suav nrog hauv kev sib txuas ntawm cov roj fatty acids ntau dua. Cov tshuaj siv los ua zaub mov noj rau lub raum tsis ua haujlwm.
Composition
Daim foos ntawm cov tshuaj "Ketoanalogues ntawm amino acids" - ntsiav tshuaj, zaj duab xis-coated.
Cov tshuaj muaj pes tsawg leeg yog ib qho nyuaj ntawm kaum yam tsim nyog rau kev ua haujlwm tag nrho ntawm lub cev. Cov khoom xyaw nquag:
- α-keto analogue ntawm isoleucine (67 mg). Nws tsis tuaj yeem tsim tawm hauv lub cev, thiab yog li yuav tsum tau los ntawm cov khoom noj.
- Leucine alpha-keto analogue (101mg). Qhov tsis muaj leucine hauv lub cev feem ntau yog vim qhov nce hauv cov tshuaj estrogen.
- Keto-phenylalanine calcium monohydrate (68 mg).
- Ketalin calcium (86 mg). Ua ke nrog isoleucine thiab leucine, valine ua lub zog rau cov leeg hlwb.
- Methionine alpha hydroxy analogue (59 mg). Methionine pab txo cov roj cholesterol, txhim kho daim siab ua haujlwm.
- YLysine monoacetate (105 mg).
- Threonine (53 mg). Cov amino acid koom nrog hauv kev sib txuas ntawm collagen thiab elastin.
- YTryptophan (23 mg).
- Histidine (38 mg). Heterocyclic amino acid txhawb cov ntaub so ntswg loj hlob thiab rov tsim dua tshiab.
- YTyrosine (30 mg). Amino acid txhawb kev tsim cov melanin, txhim kho kev ua haujlwm ntawm cov qog adrenal.
Tshuaj yeeb thiab tshuaj qhia
Kev txo qis hauv lub raum ua haujlwm ua raukev cuam tshuam ntawm lub cev. Kev kho tus kab mob no muaj cov tsos mob thiab kev noj zaub mov tshwj xeeb. Kev noj zaub mov yog kev noj zaub mov tsawg uas muaj cov amino acids.
Ketoanalogues ntawm cov amino acids hauv cov ntsiav tshuaj tau sau rau lub raum tsis ua haujlwm kom muab lub cev nrog cov as-ham. Cov tshuaj ua tiav lub cev nrog cov khoom siv uas yog lub zog txawm tias tau txais nitrogen tsawg.
Cov tshuaj no maj mam txo qhov tsim ntawm urea thiab txo cov concentration ntawm uremic toxins.
Ketoanalogues tsis ua rau muaj qhov nce hauv glomerular pom hauv cov nephrons ntxiv. Keto-muaj cov tshuaj muaj txiaj ntsig zoo rau lub raum hyperphosphatemia: lawv txo cov ntsiab lus ntawm creatine hauv cov ntshav, muaj cov nyhuv nephroprotective, thiab tiv thaiv qhov pib ntawm theem kawg txaus ntshai ntawm lub raum ua haujlwm ploj mus. Amino acids txhim kho kev kawm ntawm fibrous generalized osteodystrophy.
Cov tshuaj tau sau tseg rau kev tiv thaiv thiab kho cov protein metabolism hauv cov neeg laus thiab menyuam yaus hnub nyoog 3 xyoos uas muaj lub raum tsis zoo.
Txoj kev ntawm daim ntawv thov thiab kev suav ntau npaum li cas
Cov ntsiav tshuaj "Ketoanalogues ntawm amino acids" tau noj hauv qhov ncauj nrog zaub mov. Nws ntseeg tau tias nrog txoj kev no, kev nqus thiab cov metabolism hauv cov khoom ntawm cov khoom tau zoo dua.
Cov tshuaj tau pom zoo siv txij li peb xyoos. Kev suav ntau npaum li cas nyob ntawm tus neeg mob lub cev hnyav. Muab 1 ntsiav tshuaj (0.1 g) rau 5 kg ntawm lub cev hnyav ib hnub. Tsis txhob zom cov ntsiav tshuaj thaum noj.
Tshuajhaus kom txog thaum lub glomerular pom tus nqi tsis tshaj 25 ml / min. Nyob rau tib lub sijhawm, cov neeg mob yuav tsum ua raws li kev noj zaub mov tsis muaj protein ntau: tsis pub ntau tshaj 40 g ib hnub rau cov neeg laus thiab 1.4-0.8 g ntawm cov protein ib 1 kg ntawm lub cev hnyav rau menyuam yaus.
Thaum kho, cov ntsiab lus calcium hauv cov ntshav tau saib xyuas tas li. Nrog nws nce, txo qhov koob tshuaj.
"Ketoanalogues ntawm amino acids": analogues
Kev lag luam kws tshuaj tsim ntau yam tshuaj uas muaj cov proteins thiab cov amino acids rau kev noj zaub mov rau parenteral. Txawm hais tias lawv lub hom phiaj dav dav, lawv raug sau rau qee yam kab mob, nyob ntawm qhov muaj pes tsawg leeg. Ntawm cov tshuaj no, tsis muaj ntau cov uas tau noj rau lub raum tsis ua haujlwm. Lawv raug tsim nyob rau hauv ntau lub teb chaws thiab muaj ntau lub npe.
"Keto analogs ntawm amino acids" - cov npe lag luam:
- "Ketosteril" yog ib yam tshuaj siv los kho lub raum thiab cov protein-zog noj tsis txaus. Chaw tsim tshuaj paus - German tuam txhab Fresenius Kabi Deutschland GmbH;
- "Ketoaminol" - cov ntsiav tshuaj tau sau los them nyiaj rau qhov tsis muaj cov amino acids nrog cov khoom siv metabolic. Chaw tsim tshuaj paus suav tshuaj tuam txhab Nanjing Baijinyu Pharmaceutical;
- "Aminoven Infant" - tshuaj rau kev noj zaub mov rau niam txiv.
Cov tshuaj saum toj no yog siv dav hauv kev kho mob raum tsis ua haujlwm. Lwm cov tshuaj tau sau tseg hauv txoj kev kho mob los ntawm qhov tsis txaus ntawm cov amino acids tseem ceeb:
- "Aminosteril" - ib qho tshuaj rau kev txhaj tshuaj thiab tso dej. Cov tshuaj yog tsim los pab them rau qhov tsis muaj cov proteins;
- "Nefrotekt" - ib qho kev daws rau kev txhaj tshuaj rau hauv cov hlab ntsha, muab tshuaj los kho cov protein-zog sib npaug hauv cov kab mob ntawm lub raum thiab cov ureter;
- "Nutriflex 70/180 lipid" - ib qho emulsion tsim los ntxiv cov as-ham thaum noj zaub mov zoo tsis tuaj yeem lossis contraindicated.
Ketoaminol
Cov khoom lag luam yog cov tshuaj generic "Ketoanalogues ntawm amino acids". Cov tshuaj yog tsim nyob rau hauv cov ntsiav tshuaj, uas yog coj los tiv thaiv thiab kho pathological kev hloov nyob rau hauv cov protein metabolism tshwm sim los ntawm ib tug zuj zus poob nyob rau hauv lub raum functionality. "Ketoaminol" yog sau ua ke nrog kev noj haus, nrog rau cov khoom noj muaj protein tsawg.
Kev noj tshuaj yog xam raws tus neeg mob hnyav 0.1g / kg ib hnub. Tsis zoo li cov tshuaj "Ketoanalogues ntawm amino acids", cov tshuaj tau pom zoo rau kev siv tsuas yog tom qab tus neeg mob mus txog 18 xyoo. Ntxiv nrog rau hnub nyoog, muaj ntau yam contraindications:
- hypersensitivity rau cov tshuaj uas tsim cov ntsiav tshuaj;
- mob ntawm cov amino acid metabolism;
- siab ntshav calcium;
- prescribe nrog ceev faj rau cov neeg mob uas muaj keeb kwm yav dhau los rau phenylketonuria.
Vim tsis muaj kev soj ntsuam ntawm cov tshuaj ntawm tus menyuam hauv plab, cov poj niam cev xeeb tub yuav tsum siv cov tshuaj kom ceev faj.
Ketosteril
tshuaj kho mobCov tshuaj "Ketosteril" zoo ib yam li cov nyhuv tshuaj ntawm cov tshuaj "Ketoanalogues ntawm amino acids". Cov txheej txheem ntawm kev ntxiv lub cev nrog cov enzymes tsim nyog thiab cov organic acids tshwm sim vim kev hloov pauv. Ua kom cov txheej txheem ntawm kev noj zaub mov kom raug xaiv cov ntsiab lus ntawm carbohydrates (glucose), rog (lipids) thiab lwm yam. Yog hais tias keto analogue ntawm aspartate yog glutamate, ces kom ceev cov tshuaj tiv thaiv transamination, cov piam thaj cov ntsiab lus hauv cov zaub mov yog me ntsis nce.
Cov tshuaj txhim kho cov metabolism hauv cov protein, txo cov tshuaj lom ntawm cov khoom lag luam metabolic, tsis tas yuav nce qib ntawm glomerular pom. "Ketosteril" rhuav tshem cov urea, ua kom nrawm ntawm kev siv cov khoom noj uas muaj nitrogen.
Thaum kho, saib xyuas qhov concentration ntawm calcium hauv cov ntshav. Txhawm rau tiv thaiv hypercalcemia, kev siv tshuaj uas txhim kho calcium nqus tau raug cais tawm: Ciprofloxacin, quinolone derivatives, kev npaj hlau.
Aminoven Me Nyuam
Means rau parenteral khoom noj "Aminoven Infant" tuaj yeem hu ua "Ketoanalogues ntawm amino acids". Cov tshuaj tsuas yog siv rau kev kho mob hauv tsev kho mob xwb, vim tias nws muaj daim ntawv ntau npaum ntawm cov tshuaj rau kev txhaj tshuaj ntawm 6 thiab 10%.
Aminoven Me nyuam mos muaj tib cov amino acids raws li nws cov suav suav. Cov tshuaj no yog siv rau kev noj haus parenteral, muab tso rau hauv cov hlab ntsha los yog drip feem ntau mus rau hauv cov hlab ntsha hauv nruab nrab.
Cov koob tshuaj raug xaiv tus kheej, nyob ntawm lub hnub nyoog, yam ntxwv ntawm lub cev thiab cov txiaj ntsig kho. "Aminoven Infant" raug muab tshuaj kom txog thaum tus neeg mobyuav tau txais cov as-ham txaus los ntawm kev noj zaub mov zoo.
Reviews
Cov kab mob uas tau muab tshuaj noj rau niam txiv yog qhov hnyav heev. Qee cov neeg mob emaciated heev uas lawv tsis tau sawv ntawm txaj. Tias yog vim li cas thiaj li muaj qee qhov kev tshuaj xyuas txog "Ketoanalogues ntawm amino acids", lawv tau tso tseg feem ntau los ntawm cov txheeb ze ntawm cov neeg mob.
Cov neeg siv hais tias lawv tsis nkag siab qhov kev sim, tab sis lawv pom tias kev noj qab haus huv ntawm lawv cov neeg hlub tau zoo dua qub tom qab siv tshuaj. Cov kws kho mob paub tseeb tias muaj kev cuam tshuam, thiab nws tsis yog luv luv. Muaj tseeb tiag, qee leej niam nco ntsoov tias cov menyuam yaus haus cov tshuaj hauv cov ntsiav tshuaj nrog kev tsis txaus siab, vim tias cov tshuaj yog tawv thiab iab. Nws yuav siv sij hawm ntev los yaum lossis dag kom tus menyuam haus cov tshuaj.
Cov neeg uas tau tawm mus thiab tab tom kho mob sab nraud sau tias cov tshuaj yog qhov zoo rau kev tswj hwm cov amino acids uas yuav tsum tau ua hauv tsev. Tsis tas yuav mus "drips" lossis hu rau tus kws saib mob hauv tsev.
