Tshuaj "Biseptol": cov lus qhia rau kev siv, piav qhia thiab tshuaj xyuas

2024 Tus sau: Curtis Blomfield | [email protected]. Kawg hloov kho: 2023-12-16 21:10

Hauv kab lus, xav txog cov lus qhia rau kev siv Biseptol. Nws yog ib qho tshuaj sib xyaw nrog ntau qhov kev ua haujlwm. Muaj nyob rau hauv pab pawg ntawm sulfonamides. Nws yog siv rau ntau yam kab mob. Kev tshuaj xyuas txog nws feem ntau yog qhov zoo.

Kev sib xyaw ntawm Biseptol, tso tawm daim ntawv

"Biseptol" yog tsim los ntawm cov chaw tsim khoom hauv ntau hom tshuaj:

1. Nyob rau hauv daim ntawv ntawm cov ntsiav tshuaj nrog ib koob ntawm 120 mg. Nyob rau hauv cov ntaub ntawv no, txhua ntsiav tshuaj ntawm cov tshuaj muaj sulfamethoxazole nyob rau hauv ib tug npaum li ntawm 100 mg thiab trimethoprim nyob rau hauv ib tug npaum li ntawm 20 mg. Raws li cov koom haum pab, polyvinyl cawv, talc, aseptin P, magnesium stearate, aseptin M, qos starch, propylene glycol yog siv. Cov ntsiav tshuaj tau ntim rau hauv ib lub hlwv ntawm tes, 20 daim nyob rau hauv ib lub hlwv. Txhua lub thawv muaj ib qho ntawm lawv.
2. Nyob rau hauv daim ntawv ntawm cov ntsiav tshuaj nrog ib koob ntawm 480 mg. Hauv qhov no, txhua lub ntsiav tshuaj Biseptol muaj sulfamethoxazole hauv tus nqi ntawm 400 mg, nrog rau trimethoprim hauv qhov nyiaj ntawm 80 mg. Cov khoom xyaw ntxiv yog zoo ib yam li cov tshuaj hauv cov ntsiav tshuaj uas muaj ntau npaum li 120 mg. Txhua lub thawv ntawm cov tshuaj kuj muaj ib lub hlwv contour uas muaj 20 ntsiav tshuaj. Yog li nws tau hais hauv cov lus qhia rau kev siv rau Biseptol. Txawm li cas los xij, muaj lwm yam kev tso tawm.
3. Nyob rau hauv daim ntawv ntawm kev ncua kev npaj rau kev tswj qhov ncauj. Suspension "Biseptol" muaj ib tug strawberry tsw thiab lub teeb cream xim. Txhua 5 ml muaj sulfamethoxazole 200 mg thiab trimethoprim 40 mg. Strawberry tsw, purified dej, propylene glycol, propylhydroxybenzoate, m altitol, citric acid, sodium saccharinate, methylhydroxybenzoate, sodium carboxymethylcellulose ntsev, Cremophor RH 40, sodium hydrogen phosphate, magnesium aluminium silicate yog siv los ua cov khoom siv ntawm cov khoom siv. Cov tshuaj tau ntim rau hauv 80 ml fwj ua los ntawm iav tsaus. Txhua lub thawv muaj ib lub raj mis tshuaj. Indications thiab contraindications rau kev siv ntawm "Biseptol" nyob rau hauv txhua daim ntawv ntawm kev tso tawm yuav zoo ib yam.
4. Nyob rau hauv daim ntawv ntawm cov concentrate npaj rau kev npaj ntawm kev daws rau infusion. Ntim hauv 5 ml iav ampoules. Txhua milliliter ntawm cov concentrate muaj 80 mg ntawm sulfamethaxazole thiab 16 mg ntawm trimethoprim. Txhua lub thawv muaj 10 ampoules.

Cov lus qhia rau kev siv "Biseptol"

Cov tshuaj yog npaj rau kev kho mob ntawm cov kab mob uas muaj kab mob sib kis thiab inflammatory etymology thiab rhiab rau cov ntsiab lus tseem ceeb ntawm cov tshuaj.nyiaj:

1. kab mob ua pa, suav nrog pleural empyema, ntsws abscesses, pneumonia, bronchitis.
2. Sinusitis thiab otitis.
3. Kab mob cuam tshuam rau cov kab mob genitourinary, suav nrog prostatitis, salpingitis, urethritis, pyelonephritis.
4. kab mob gonorrhea.
5. Kab mob cuam tshuam rau txoj hnyuv, nrog rau raws plab, kab mob cholera, kab mob plab kab mob, kab mob paratyphoid, typhoid fever.
6. Kab mob cuam tshuam rau cov nqaij mos thiab tawv nqaij, suav nrog pyoderma thiab furunculosis.

Cov lus qhia rau kev siv "Biseptol" yuav tsum tau ua nruj me ntsis saib.

Contraindications rau noj

"Biseptol" yog contraindicated rau kev nkag yog tias muaj cov kab mob hauv qab no lossis cov xwm txheej:

1. Nrog kuaj pom kev puas tsuaj rau lub siab parenchyma.
2. Nrog rau lub raum ua haujlwm tsis zoo, thaum nws tsis tuaj yeem tswj hwm qhov concentration ntawm cov tshuaj hauv cov ntshav.
3. Nyob raum tsis zoo.
4. Nyob rau hauv cov kab mob ntshav hnyav, suav nrog ntshav qab zib vim tsis muaj folic acid, megaloblastic anemia, leukopenia, agranulocytosis, B12-deficiency anemia, aplastic anemia.
5. Nrog hyperbilirubinemia thaum yau.
6. Thaum kuaj pom tias tsis muaj qabzib-6-phosphate dehydrogenase.
7. Nyob rau hauv cev xeeb tub, lactation.
8. Hnub nyoog 0-3 lub hlis (rau txhaj tshuaj), hnub nyoog txog 36 lub hlis (rau kev ncua).
9. Thaum muaj kev kub ntxhov rau ib qho khoom siv nrog rautshuaj muaj pes tsawg leeg.

Kev saib xyuas yuav tsum tau ua thaum muab tshuaj Biseptol yog tias tus neeg mob muaj cov thyroid pathologies, folic acid tsis txaus, cov tsos mob ntawm bronchial hawb pob.

Cov lus qhia rau kev siv rau cov ntsiav tshuaj Biseptol (120 mg) yog cov ncauj lus kom ntxaws.

KOJ

Pills, intramuscular lossis intravenous tswj rau cov neeg mob uas muaj hnub nyoog 12 xyoos raug muab tshuaj rau ob zaug ntawm 480 mg ib hnub lossis ib koob ntawm 960 mg. Yog tias tus kab mob hnyav heev, koob tshuaj triple ntawm 480 mg tau qhia. Yog tias tus kab mob muaj cov kab mob ntev, ob zaug koob tshuaj 480 mg ib hnub yog qhia. Tab sis tsis tsawg.

Cov menyuam yaus txog 24 lub hlis tau pom ob zaug ib koob ntawm 120 mg, cov menyuam yaus hnub nyoog 2-6 xyoo tau pom ob zaug hauv ib hnub mus txog 240 mg, cov menyuam hnub nyoog 6-12 xyoos tau pom ob zaug ntxiv. rau 480 mg.

Kev ncua yuav tsum tau noj tom qab noj mov nrog dej ntau. Qhov no tau lees paub los ntawm cov lus qhia rau kev siv. Tus nqi thiab kev qhia ntawm "Biseptol" yog qhov txaus siab rau ntau tus.

Cov neeg mob hnub nyoog 12 xyoos thiab laus dua tau muab 960 mg txhua 12 teev. Yog tias tus kab mob hnyav, nce mus txog 1440 mg txhua 12 teev. Cov kev kho mob ntawm cov kab mob cuam tshuam rau cov zis yog 10-14 hnub, mob ntsws bronchitis - ob lub lis piam, shigellosis, cov neeg taug kev raws plab - 5 hnub.

Cov menyuam yaus hnub nyoog 3-6 lub hlis tau pom ob zaug hauv ib hnub, 120 mg ntawm kev ncua, cov menyuam hnub nyoog 7-36 lub hlis tau pom ob zaug txog li 240 mg, cov menyuam hnub nyoog 4-6 xyoo tau pom ob zaug Txog li 480 mg, cov menyuam hnub nyoog 7-12 xyoos tau pom ob zaug txog 480 mg.

Yam tsawg kawg ntawm kev kho mobyog 4d. Kev kho mob yuav tsum tau txuas ntxiv rau ob hnub tom qab cov tsos mob ntawm tus kab mob tau ploj mus. Kev kho mob yuav ntev dua yog tias tus kab mob nyob rau hauv daim ntawv ntev. Yog li, kev kho tus mob brucellosis tuaj yeem ncav cuag 3-4 lub lis piam, thiab ua npaws typhoid - 4-12 lub lis piam.

txhawm rau tiv thaiv kev rov tshwm sim ntawm cov kab mob sib kis ntawm cov zis, cov neeg mob hnub nyoog 12 xyoos tau muab tshuaj ib zaug hmo ntuj ntawm 4480 mg ntawm cov tshuaj, rau cov neeg mob hnub nyoog qis dua 12 xyoos - 12 mg. / kg ib hnub twg. Kev tiv thaiv kev kho mob yog nqa tawm hauv 1-12 lub hlis. Hauv kev kho mob cystitis mob rau cov neeg mob hnub nyoog 7-16 xyoo, tau muab ob zaug ntawm 480 mg ntawm cov tshuaj, chav kawm yog 3 hnub.

Kev kho tus kab mob gonorrhea yog siv cov tshuaj ntau txog 2880 mg, uas yuav tsum tau muab faib ua peb koob. Qhov no tau qhia hauv cov lus qhia rau kev siv rau Biseptol. Tus nqi yuav qhia hauv qab no.

Kev kho tus mob gonorrheal pharyngitis, yog tias tus neeg mob muaj kev nkag siab ntau ntxiv rau penicillins, suav nrog ib koob tshuaj 4320 mg rau 5 hnub. Kev kho mob ntsws pneumonia provoked los ntawm Pneumocystis carinii koom nrog kev noj tshuaj rau ob lub lis piam, txhua 6 teev ntawm 120 mg / kg / hnub.

Intramuscularly, cov neeg mob hnub nyoog tshaj 12 xyoos yog muab 480 mg txhua 12 teev, cov menyuam hnub nyoog 6-12 xyoos - 240 mg.

Kev tso dej rau hauv cov neeg mob hnub nyoog tshaj 12 xyoos yog muab txhua 12 teev ntawm 960-1920 mg, cov neeg mob 6-12 xyoo - 480 mg txhua, cov neeg mob hnub nyoog 6-30 hli - 240 mg, cov neeg mob 1, 5- 5 lub hlis - 120 mg. Nws yog ib qho tseem ceeb kom ua raws li cov lus qhia thiab cov lus qhia rau kev siv Biseptol.

Qhov kev ua tau zoo tshaj plaws ntawm cov tshuaj tau ua tiav yog tias nws cov concentration tas li nyob rau hauv cov ntshav yog nyob rau theem ntawm 5 mcg / ml.

Nyob rau hauv kev kho mob malaria provoked los ntawm Plasmodium falciparum, infusions yuav tsum tau nqa tawm ob zaug ib hnub twg, ntawm 1920 mg. Kev kho mob yog nqa tawm ob hnub. Txo cov koob tshuaj rau menyuam yaus.

Txhawm rau kom ua tiav cov concentration ntawm cov tshuaj hauv cov ntshav, nws yog siv los ntawm drip intravenously, yav tas los yaj hauv 200 ml ntawm cov kuab tshuaj tshwj xeeb. Infusions yog nqa tawm ob zaug ib hnub, rau ib teev.

Y Ua ntej kev tswj hwm, cov tshuaj tau yaj hauv cov tshuaj infusion hauv cov proportions hauv qab no: 5 ml ntawm cov tshuaj hauv daim ntawv ntawm cov tshuaj rau 125 ml ntawm cov tshuaj infusion, 10 ml rau 125 ml, 15 ml rau 500. ml.

Yog tias pom muaj crystallization lossis turbidity hauv cov tshuaj, nws txwv tsis pub siv. Kev taw qhia yog ua rau 1-1.5 teev, nyob ntawm tus neeg mob xav tau cov kua dej.

Yog tias tsim nyog los txwv cov kua dej nkag mus rau hauv lub cev, kev daws teeb meem yog siv ntau dua - 5 ml ntawm cov tshuaj yog yaj hauv 75 ml ntawm kev daws rau infusion. Cov koob tshuaj tuaj yeem nce ntxiv ntawm qhov kev txiav txim siab ntawm tus kws kho mob los ntawm 50% yog tias muaj kab mob loj heev tau kho.

Tsis yog txhua tus paub cov lus qhia rau kev siv Biseptol.

Side Effects

Feem ntau, cov tshuaj tau zam los ntawm cov neeg mobzoo, tab sis cov tsos ntawm qhov tsis zoo tshwm sim ntawm lub cev, xws li:

1. YHyponatremia, hyperkalemia, metabolic hypoglycemia.
2. Cov tshuaj tsis haum - scleral hyperemia, erythema multiforme exudative, kub taub hau, angioedema, tsis haum myocarditis, Stevens-Johnson syndrome, exfoliative dermatitis, ua pob, kub taub hau, urticaria, photosensitivity, pruritus, Lyell's syndrome.
3. Myalgia thiab arthralgia los ntawm musculoskeletal system.
4. Cov kab mob tso zis tuaj yeem ua rau muaj qhov tshwm sim ntawm cov tshuaj lom nephropathy nrog anuria thiab oliguria, hypocreatininemia, nce urea concentration, hematuria, crystalluria, lub raum tsis ua haujlwm, interstitial nephritis, polyuria.
5. Hematopoietic system: methemoglobinemia, hypoprothrombinemia, eosinophilia, megaloblastic anemia, hemolytic anemia, aplastic anemia, agranulocytosis, neutropenia, thrombocytopenia, leukopenia.
6. Cov kab mob hauv plab: pancreatitis, pseudomembranous enterocolitis, kab mob siab, kab mob siab, cholestatic jaundice, nce kev ua haujlwm ntawm daim siab transaminases, cholestasis, stomatitis, glossitis, mob plab, gastritis, raws plab, tsis qab los noj mov, xeev siab, ntuav.
7. Cov kab mob ua pa: qhov pom ntawm pulmonary infiltrates, hnoos, choking, bronchospasm.
8. Nervous system: peripheral neuritis, tremor, apathy, aseptic meningitis nyob rau hauv tsawg zaus, kev nyuaj siab, kiv taub hau thiab mob taub hau.

Cov lus qhia rau kev siv cov tshuaj Biseptol yog qhov dav heev.

Ntau tshaj

Cov tsos mob ntawm kev noj tshuaj ntau dhau ntawm sulfonamides yog raws li nram no: tus neeg mob poob qab los noj mov, plab hnyuv colic tshwm, crystalluria, hematuria, kub taub hau, tsis nco qab, tsaug zog, mob taub hau, kiv taub hau, ntuav, xeev siab.

Thaum noj tshuaj ntau dhau ntawm trimethoprim, xeev siab thiab ntuav, kiv taub hau, mob taub hau, kev nyuaj siab, thiab kev puas hlwb tsis raug cais tawm. Tej zaum yuav muaj inhibition ntawm kev ua haujlwm ntawm cov pob txha pob txha.

Tam sim no, cov tshuaj tsis muaj ntaub ntawv hais txog ntau npaum li cas co-trimoxazole tuaj yeem ua rau muaj kev phom sij.

Yog tias tus neeg mob noj co-trimoxazole rau lub sijhawm ntev, kev noj tshuaj ntau dhau yuav tshwm sim. Hauv qhov no, kev ua haujlwm ntawm cov pob txha pob txha yog inhibited, megaloblastic anemia, leukopenia, thiab thrombocytopenia tsim.

Yog tias pom tias muaj cov tsos mob ntawm kev noj tshuaj ntau dhau, koj yuav tsum tsis txhob noj Biseptol tam sim ntawd thiab ntsuas kom tshem tawm ntawm lub plab zom mov. Hauv qhov siab kawg ntawm 2 teev tom qab koob tshuaj kawg, nws yog ib qho tseem ceeb uas yuav tsum tau ua rau plab hnyuv, lossis ua rau ntuav. Yog tias tus neeg mob lub diuresis tsis txaus, tab sis lub raum ua haujlwm tau khaws cia, nws pom tias haus dej ntau. Nws kuj raug pom zoo kom noj txog li 10 mg / hnub ntawm calcium folinate. Kev tshem tawm ntawm trimethoprim yog yooj yim los ntawm kev nce acidity ntawm cov zis, tab sis muaj kev pheej hmoo tias sulfonamide yuav crystallize hauv ob lub raum.

Nws yog ib qho tsim nyog los soj ntsuam cov duab ntawm cov ntshav, muaj pes tsawg leeg ntawm electrolytes, thiab lwm yam biochemic altsis muaj. Qhov ua tau zoo ntawm kev lim ntshav peritoneal tsis tuaj, qhov ua tau zoo ntawm hemodialysis yog nruab nrab. Qhov no qhia peb cov lus qhia rau kev siv. Biseptol analogues yuav tsum tau xaiv los ntawm kws kho mob.

Kev sib tham nrog lwm yam tshuaj

Kev kho ib txhij nrog Biseptol thiab thiazide diuretics tuaj yeem ua rau muaj kev loj hlob ntawm thrombocytopenia thiab los ntshav. Cov tshuaj ua ke no tsis pom zoo.

Co-trimoxazole tuaj yeem nce kev ua haujlwm ntawm cov tshuaj tiv thaiv tsis ncaj ncees, methotrexate, tshuaj hypoglycemic.

Raws li kev cuam tshuam ntawm co-trimoxazole, cov metabolism hauv siab ntawm phenytoin thiab warfarin raug txo, thaum lawv qhov kev ua tau zoo dua qub.

Lub neej ib nrab ntawm trimethoprim txo qis nrog kev tswj hwm ntawm rifampicin.

Kev siv ntau npaum ntawm piracetam ua rau muaj kev pheej hmoo ntawm megaloblastic anemia.

Cov txiaj ntsig ntawm "Biseptol" txo qis yog tias siv procainamide, procaine, benzocaine sib npaug.

Kev kho ib txhij nrog phenytoins, barbiturates, PAS pab txhawb kev ua kom pom tseeb ntawm folic acid deficiency.

Raws li cov lus qhia tag nrho rau "Biseptol", nws qhov kev ua tau zoo dua qub thaum noj cov derivatives ntawm salicylic acid.

Raws li kev cuam tshuam ntawm cov tshuaj, cov nyhuv kho ntawm tricyclic antidepressants, tshuaj tiv thaiv qhov ncauj txo qis.

Kev siv tshuaj ib txhij nrog cov tshuaj uas tuaj yeem cuam tshuam cov pob txha pob txha hematopoiesisnce kev pheej hmoo ntawm myelosuppression.

Thaum noj cholestyramine, qhov nqus ntawm lwm cov tshuaj txo qis, thiab yog li nws raug nquahu kom noj lawv ua ntej noj co-trimoxazole 4-6 teev, lossis ib teev tom qab siv.

Cov lus qhia rau kev siv tshuaj "Biseptol" peb tau txiav txim siab.

Analogues

Lub ntsiab lus ntawm cov tshuaj Biseptol hais txog kev kho mob yog cov tshuaj sulfanilamide xws li Ingaflu, Ingalipt, Dermazin, Asakol.

Ntawm cov ntsiab lus ntawm cov tshuaj tuaj yeem raug sau tseg "Trimosul", "Sulotrim", "Sinersul", "Cotrimaxazole", "Cotrimaxol", "Oriprim", "Novotrimed", "Expazol", "Rancotrim", "Sulfatrim", "Primotren", "Eriprim", "Cotribene", "Bactreduct", "Vanadil", "Trimexazole", "Baktekod", "Aposulfatrin", "Vanadil", "Microcetim", "primazol", "Infectrim" ", "Methomid", "Falprin", "Gantrin", "Bactramel". "Abactrim", "Bactifer", "Andoprim", "Abacin", "Bactramine", "Bacterial", "Bactrim"

Cov lus qhia rau kev siv thiab tus nqi ntawm Biseptol analogues yuav tsis raug txiav txim siab. Hauv qab no yog tus original.

Tus nqi

Tus nqi ntawm cov khoom siv tshuaj txawv nyob ntawm thaj tsam ntawm kev muag khoom thiab cov khw muag tshuaj uas nws muag. Tus nqi nruab nrab rau ib pob ntawm Biseptol ntawm ib koob ntawm 120 mg yog 30 rubles, rau ib pob ntawm ib koob ntawm 480 mg - 68 rubles. Tus nqi ntawm ib pob "Biseptol" nyob rau hauv ampoules fluctuates nyob rau theem ntawm 350 rubles, thiab ib lub raj mis ntawm kev ncua - nyob rau theem ntawm 120 rubles.

Nrog cov lus qhia hauv cov lus qhia siv rau"Biseptol" tuaj yeem pom, tab sis tsis muaj ntaub ntawv hais txog tus nqi.

Tshuaj xyuas txog "Biseptol"

Cov neeg mob thiab kws kho mob feem ntau tawm tswv yim zoo txog "Biseptol" yog cov tshuaj uas muaj txiaj ntsig zoo tshaj plaws tiv thaiv kab mob ua pa (bronchiectasis, furunculosis, otitis media, bronchial hawb pob).

Ntau zaus, cov tshuaj tsis zoo hauv kev kho mob gonorrhea thiab pob txuv.

Cov neeg mob kuj tau tshaj tawm tias ntau zaus, thaum noj cov tshuaj, cov tshuaj tsis zoo ntawm lub cev xws li xeev siab thiab ntuav, ua rau poob qab los loj heev. Ntau tus xav txog Biseptol yog cov tshuaj uas tsis muaj hnub nyoog. Txawm li cas los xij, qhov txiaj ntsig tsis txaus ntseeg yog tus nqi kev ywj pheej ntawm cov tshuaj thiab nws muaj rau cov pej xeem. Thiab dhau li ntawd, nws muaj ib daim ntawv teev cov lus qhia dav dav. Raws li kev tshuaj xyuas, cov lus qhia rau kev siv "Biseptol" yog qhov yooj yim thiab meej.

Nws yog ib qho tseem ceeb uas yuav tsum nco ntsoov tias kev xaiv tshuaj rau kev kho mob ntawm cov kab mob sib kis yuav tsum tau ua los ntawm tus kws kho mob tshwj xeeb uas tuaj yeem suav nrog cov contraindications uas twb muaj lawm thiab tus yam ntxwv ntawm txhua tus neeg mob.

Peb tau saib seb Biseptol pab nrog dab tsi. Daim ntawv teev cov kab mob zoo heev.