Lub neej ntawm ib tug neeg niaj hnub no muaj kev ntxhov siab, thaum kev pab sab nraud ntawm cov tshuaj tshwj xeeb dhau los ua qhov tsim nyog. Ib qho ntawm cov tshuaj no yog Afobazol ntsiav tshuaj. Cov lus qhia rau kev siv, tshuaj xyuas txog lawv tau tham hauv qab no.
Pharmacological daim ntawv ntawm cov tshuaj
Raws li cov lus qhia rau kev siv, "Afobazol" tuaj yeem yuav hauv lub network ntawm cov khw muag tshuaj hauv daim ntawv ntsiav tshuaj. Txhua chav tsev ntawm cov tshuaj muaj ib tug puag ncig tiaj tus, chamfered raws ntug. Cov xim ntawm cov ntsiav tshuaj yog dawb, tej zaum yuav muaj ib tug me ntsis creamy tint. Ib pob muaj 60 ntsiav tshuaj, ntim 20 nyob rau hauv ib lub hnab ntawv nyiaj-coated.
Pharmacological pawg
Cov kws tshaj lij tau tsim kev faib tshuaj raws li lawv cov kws kho mob koom nrog. Kev faib mus rau hauv pharmacological pawg ntawm cov tshuaj yog nqa tawm raws li lawv lub hom phiaj, uas yog, qhov kev txiav txim exerted rau tib neeg lub cev. Cov lus qhia rau kev siv rau "Afobazole" qhia tau hais tias nws belongs rau lub pharmacological pab pawg neeg ntawm tranquilizers.anxiolytic.
Yuav ua li cas hauv tshuaj?
Tshuaj pab ua kom lub siab lub ntsws zoo, txo kev ntxhov siab, ntxhov siab, tau siv txij li thaum ub, tej zaum txij thaum yug los ntawm cov tshuaj raws li kev tshawb fawb thiab kev coj ua. Cov kws muag tshuaj tab tom tsim ntau yam tshuaj uas ua raws li cov tshuaj sib txawv, tab sis muaj qhov zoo sib xws ntawm qhov kawg ntawm kev sib ntaus sib tua tiv thaiv kev ntxhov siab thiab kev ntxhov siab.
Qhov no yog qhov Afobazol ntsiav tshuaj muaj. Cov lus qhia rau kev siv qhia tias lawv muaj cov active tshuaj fabomotizol. Nws tau txais thaum pib ntawm lub xyoo pua 21st ntawm Kev Tshawb Fawb Lub Tsev Haujlwm ntawm Pharmacology ntawm Lavxias Academy ntawm Kev Tshawb Fawb. Nws cov synthesis yog tshwm sim los ntawm kev tshawb fawb mus sij hawm ntev rau cov tshuaj uas muaj cov tshuaj tiv thaiv kev ntxhov siab, tab sis tsis muaj kev phiv, raws li benzodiazepine tau siv dav hauv kev kho mob ntawm kev ntxhov siab. Tam sim no, cov tshuaj no yog ib feem ntawm cov tshuaj, uas yog tsim nyob rau hauv Russia nyob rau hauv lub npe "Afobazol".
Nyob rau hauv cov lus qhia rau kev siv contraindications, cov kev phiv los ntawm cov tshuaj no tau piav qhia los ntawm cov chaw tsim tshuaj paus ntawm PJSC "OTCPharm". Tab sis muab hais tias tsis muaj kev sim tswj randomized tau ua rau fabomotizole, cov tshuaj no tsis yog cov tshuaj thawj zaug. Lub peev xwm ntawm cov tshuaj nquag cuam tshuam nrog qee yam ntawm tib neeg lub cev tau tshawb xyuas los ntawm Fabkis lub tuam txhab CEREP siv lub radioligand.tsom xam.
Rau tus neeg mob thiab tus kws kho mob tshwj xeeb, tag nrho cov ntaub ntawv tsim nyog yuav raug piav qhia kom ntxaws txog cov tshuaj "Afobazol" cov lus qhia rau kev siv. Contraindications rau cov tshuaj no yuav tsum tau txiav txim siab thaum xaiv txoj kev kho. Lub active tivthaiv ntawm fabomotizole yog muaj nyob rau hauv ib ntsiav tshuaj ntawm 10 mg. Tsis tas li ntawd, cov chaw tsim khoom suav nrog:
- collidon 25;
- qos yaj ywm starch;
- magnesium stearate;
- Ymicrocrystalline cellulose;
- lactose monohydrate;
- polyvinylpyrrolidone nruab nrab molecular hnyav kev kho mob.
Tag nrho cov tshuaj no tsis muaj nqi kho mob, tab sis yog siv los ua cov khoom tsim.
Cov tshuaj nquag ua haujlwm li cas?
Nyob rau xyoo tas los no, ntau zaus, ntau tus neeg uas tig mus rau cov kws kho mob kom pab tau Afobazol ua tshuaj tiv thaiv kev ntxhov siab. Cov lus qhia rau kev siv, kaw los ntawm cov chaw tsim khoom hauv txhua pob ntawm cov ntsiav tshuaj, qhia tias fabomotizol, cov tshuaj ntawm cov cim tshiab ntawm anxiolytics, ua haujlwm hauv nws. Raws li kev tshawb fawb radioligand, nws pab txhawb rau kev ua haujlwm inhibition:
- sigma-1 receptor;
- MT-1 receptor (melatonin type 1 receptor);
- MT-3 receptor (melatonin receptor type 3).
Tsis tas li, fabomotizol inhibits MAO-A. Nws yuav tsum raug sau tseg tias kev ua haujlwm ntawm cov tshuaj ua ib qho inhibitor ntawm monoamine oxidase - cov khoom ntawm cov paj hlwb - thiab MT-3 receptors tsis yog.paub tseeb. Qhov kev txiav txim ntawm cov tshuaj nquag no yog vim nws cov qauv tshuaj S thiab antagonistic muaj peev xwm rau hom 1 thiab hom 3 melatonin receptors, nrog rau kev muaj peev xwm ua kom ruaj khov ntawm cov paj hlwb, qhov no ua rau lawv rhiab heev rau qhov tshwj xeeb. Cov tshuaj - inhibition mediators, uas ua kom muaj kev rov qab los ntawm lub siab lub ntsws. Kev noj tshuaj tsis cuam tshuam rau cov leeg nqaij thiab kev paub txog kev ua haujlwm ntawm tib neeg lub cev, tsis ua rau qaug zog.
Txoj kev ntawm cov tshuaj hauv lub cev yog dab tsi?
Nkag mus rau hauv lub cev los ntawm txoj hnyuv, cov tshuaj "Afobazol" sai sai absorbed rau hauv lub cev, pib nws txoj haujlwm. Yog tias tsis muaj kev cuam tshuam tsis zoo rau cov qauv ntawm tes, nws raug tshem tawm sai, ib nrab-lub neej ntawm cov tshuaj yog tsawg dua ib teev. Vim tias qhov nqus tau zoo hauv lub cev, cov tshuaj no tau yooj yim nkag mus rau hauv cov hlab ntsha vascular, uas yog, muaj cov hlab ntsha thiab cov hlab ntsha, sai sai txav ntawm cov ntshav ntshav mus rau cov hlab ntsha receptors. Cov lus qhia rau kev siv cov ntsiav tshuaj Afobazole qhia tias cov tshuaj nquag koom nrog hauv ib hom "kho" ntawm cov paj hlwb receptors, ua kom lawv rhiab heev rau inhibitory mediators.
Hauv tib neeg lub cev, fabomotizol hla lub siab ob zaug. Nyob rau hauv thawj lub voj voog, cov khoom ib feem ntawm cov metabolic lwj, uas ua rau cov txheej txheemhydroxylation ntawm lub nplhaib aromatic ntawm lub nplhaib benzimidazole thiab oxidation ntawm morpholine fragment. Cov tshuaj tau tawm tsuas yog nrog cov quav thiab zis nyob rau hauv daim ntawv ntawm metabolites thiab ib feem tsis hloov.
Thaum twg cov tshuaj tau sau tseg?
Qhia tag nrho cov ntaub ntawv tsim nyog txog cov tshuaj "Afobazol" cov lus qhia rau kev siv. Analogues ntawm cov tshuaj no kuj yuav tsum muaj cov lus piav qhia tsim nyog los ntawm cov chaw tsim khoom thiab koom nrog tib pab pawg kws tshuaj - anxiolytics. Cov tshuaj no yog siv los txo cov kev ntxhov siab, kev ntshai, kev ntxhov siab, kev ntxhov siab hauv kev puas siab puas ntsws thiab kev puas siab puas ntsws. Cov tshuaj "Afobazol" tsis yog cov tshuaj nyiam ntawm pawg no. Tab sis muab hais tias nws raug tso cai los ntawm lub khw muag tshuaj network yam tsis muaj kws kho mob tshwj xeeb, feem ntau nws raug pom zoo siv rau cupping:
- xov xwm;
- kev nyuaj siab;
- ntshai nro;
- ntshai;
- chim siab;
- kev ntxhov siab.
Cov chaw tsim khoom tshwj xeeb sau tseg qhov tseem ceeb ntawm cov tshuaj rau cov neeg uas muaj lub siab ntsws labile, xav tsis thoob thiab kov, tsis muaj zog thiab tsis muaj kev nyab xeeb. Cov tshuaj "Afobazol" tuaj yeem pab daws qhov tshwm sim ntawm kev ntxhov siab xws li tawm hws, qhov ncauj qhuav, kiv taub hau, insomnia thiab ntshai. Nws pab kom normalize concentration thiab nco, txo cov teeb meem somatic nyob rau hauv daim ntawv ntawm kev ua pa, lub cev muaj zog, cov leeg, hlab plawv, gastrointestinal.plab hnyuv, hnov mob.
YPuas muaj contraindications?
Ib yam li lwm yam tshuaj, tag nrho cov ntaub ntawv tsim nyog uas tseem ceeb rau tus neeg mob thiab rau tus kws kho mob tshwj xeeb yog muaj nyob rau hauv cov lus qhia rau kev siv rau cov ntsiav tshuaj Afobazol. Contraindications kuj tau piav qhia los ntawm cov chaw tsim khoom hauv qhov ntxig rau cov tshuaj:
- lactase deficiency;
- glucose-galactose malabsorption;
- galactose intolerance;
- rhiab heev rau cov khoom xyaw nquag lossis lwm yam tshuaj uas ua rau cov ntsiav tshuaj.
Vim tsis muaj kev paub txaus ntawm kev ua ntawm fabomotizole ntawm tib neeg lub cev, thaum menyuam yaus, tshwj xeeb, nws raug txwv tsis pub coj mus rau cov menyuam yaus hnub nyoog qis dua 18 xyoo. Rau tib lub laj thawj, thiab tseem yog vim muaj kev nkag mus zoo rau hauv cov kab mob vascularized, cov tshuaj yuav tsum tsis txhob noj los ntawm cov poj niam cev xeeb tub. Koj yuav tsum tsis txhob siv Afobazol rau cov niam hluas uas pub niam mis.
Yuav noj tshuaj li cas?
Tsis ntev los no, ntau zaus, los pab thaum muaj kev ntxhov siab thiab ntxhov siab, tib neeg raug pom zoo kom siv tshuaj "Afobazole". Cov lus qhia rau kev siv kom meej meej piav qhia txog kev kho mob: cov tshuaj tau noj 1 ntsiav tshuaj ntawm 10 mg ntawm 1 mus rau 3 zaug hauv ib hnub. Kev kho mob yuav tsum yog ib chav kawm, txij li thawj qhov kev txhim kho tseem ceeb hauv tus neeg mob tau pom zoo tom qab 5-8 hnub txij li pib kho. Lub sijhawm ntawm chav kawm tuaj yeem yog 3 lub hlis, tab sis nws lub sijhawmyuav tsum tau pom zoo nrog tus kws kho mob. Cov tshuaj yuav tsum tau noj tam sim tom qab noj mov nrog dej ntau.
Nyob rau hauv cov ntaub ntawv overdose
Qee tus neeg pom tias los ntawm kev noj tshuaj ntau dua lossis los ntawm kev nce ib koob ntawm cov tshuaj, lawv tuaj yeem maj nrawm rau qhov pib ntawm qhov xav tau kev kho mob. Tab sis qhov ntawd tsis yog qhov tseeb. Kev ua txhaum ntawm kev siv tshuaj Afobazole (ntau dua 3 ntsiav tshuaj ntawm 10 mg ib hnub twg) tuaj yeem ua rau muaj qhov tshwm sim hauv qab no:
- muaj zog sedation;
- tsaug zog ntau dhau.
Tsis zoo li lwm cov tshuaj sedatives, nrog kev noj ntau dhau ntawm "Afobazole" tsis pom cov leeg tsis muaj zog thiab ua haujlwm tsis zoo. Yog tias kev siv tshuaj ntau dhau tau tshwm sim tsis raug lossis txhob txwm ua, nws raug nquahu kom txhaj rau tus neeg mob subcutaneously 20% kev daws teeb meem ntawm caffeine sodium benzoate hauv tus nqi ntawm 1 ml ib 1 txhaj tshuaj 2-4 zaug hauv ib hnub. Yog tias tsim nyog, tus neeg mob yuav tsum tau muab tso rau hauv qhov chaw kho mob raws li kev saib xyuas ntawm cov kws kho mob.
Txoj kev tsis zoo tshwm sim
Ob leeg rau tus kws kho mob thiab tus neeg mob, nws yog ib qho tseem ceeb uas yuav tsum tau kawm cov lus qhia rau kev siv ua ntej pib txoj kev kho nrog Afobazol. Kev mob tshwm sim ntawm cov tshuaj yuav tsum tau txiav txim siab thaum kho. Kev tsis haum tshuaj yuav tshwm sim raws li qhov tsis zoo ntawm cov tshuaj, hauv cov xwm txheej tsis tshua muaj, cov neeg mob tau sau tseg txog kev mob taub hau uas ploj mus ntawm nws tus kheej lossis nrogpab kho mob.
Raws li tau sau tseg hauv cov lus qhia rau cov ntsiav tshuaj "Afobazol", cov tshuaj tsis cuam tshuam nrog ethyl cawv thiab sodium thiopental (ib yam khoom siv rau kev siv tshuaj loog ultrashort). Cov tshuaj tiv thaiv kev ntxhov siab no ua rau cov tshuaj tiv thaiv kev ua haujlwm ntawm carbamazepine, nrog rau cov nyhuv anxiolytic ntawm diazepam.
Yuav khaws tshuaj li cas?
Ib qho tshwj xeeb ntawm cov tshuaj "Afobazol" yog tias nws yog cov pab pawg ntawm anxiolytics. Tab sis tsis zoo li cov tshuaj zoo sib xws, uas muaj raws li lawv cov khoom siv feem ntau yog cov tshuaj los ntawm cov pab pawg ntawm benzodiazepines uas tuaj yeem ua rau muaj kev quav yeeb quav tshuaj rau tus neeg mob, fabomotizole tsis ua rau muaj kev quav yeeb quav tshuaj, txawm hais tias nws qhov kev txiav txim, tshaj tawm los ntawm cov chaw tsim khoom, yog cais los ntawm Lub Koom Haum Saib Xyuas Kev Noj Qab Haus Huv Ntiaj Teb. classifier ntawm cov tshuaj raws li txoj cai N05BX04, uas yog, nws koom nrog pab pawg ntawm lwm yam anxiolytics tau lees paub.
Ua tsaug rau nws cov khoom xyaw nquag, cov tshuaj "Afobazol" tuaj yeem yuav ntawm cov khw muag tshuaj yam tsis muaj kws kho mob tshwj xeeb. Cov ntsiav tshuaj yuav tsum tau muab khaws cia rau hauv lub pob uas lawv tau yuav, ntawm qhov kub tsis tshaj 25 0 C, kom cov menyuam tsis tuaj yeem tau. Lub txee lub neej ntawm cov tshuaj no tsuas yog 2 xyoos txij li hnub tsim khoom. Tom qab nws tas sij hawm, cov ntsiav tshuaj yuav tsum muab pov tseg raws li cov khoom pov tseg hauv tsev, lawv yuav tsum tsis txhob muab coj los siv!
Cov neeg mob hais li cas txog tshuaj?
Txhua tuscov khoom siv tshuaj yuav tsum muaj cov lus qhia los ntawm cov chaw tsim khoom. Cov lus qhia rau kev siv tshuaj "Afobazol". Contraindications, phiv, ntsiav tshuaj regimen - tag nrho cov no yog piav nyob rau hauv lub pob insert ntawm cov tshuaj. Txij li thaum cov tshuaj yog nyob rau hauv kev thov ntawm cov khw muag tshuaj sedatives, tib neeg tawm ntau qhov kev tshuaj xyuas txog nws.
Cov neeg mob uas siv nws hauv kev kho mob kev ntxhov siab, ntxhov siab, yuav luag ib txwm nco ntsoov tias "cov kev mob tshwm sim" tshwm sim tsis tshua muaj, ua qhov no ntxiv rau cov tshuaj no. Hmoov tsis zoo, nws tsis tuaj yeem hais tias cov tshuaj no feem ntau tsuas yog cov lus teb zoo xwb. Ntau tus neeg uas txiav txim siab daws qhov kev ntxhov siab nrog kev pab ntawm Afobazole xav tias nws tsis muaj txiaj ntsig. Qee tus tsis nyiam qhov tseeb tias cov ntsiav tshuaj tsis muaj qhov cuam tshuam sai, txij li thawj cov txiaj ntsig ntawm kev kho tshuaj tsuas yog tshwm sim rau hnub 5-8 tom qab pib siv. Ntawm qhov zoo, cov neeg uas tau pab cov tshuaj tiv thaiv cov kev xav tsis zoo thiab cov xwm txheej nco ntsoov tias cov tshuaj muaj txiaj ntsig zoo - ib pob ntawm 60 ntsiav tshuaj raug nqi txog 300-350 rubles.
Kev xav
Txhua cov ntaub ntawv tsim nyog rau tus neeg mob qhia txog cov tshuaj tiv thaiv kev ntxhov siab "Afobazol" cov lus qhia rau kev siv thiab tshuaj xyuas cov kws kho mob. Contraindications yog suav hais tias yog lub ntsiab lus tseem ceeb uas cov tshuaj tsis haum rau ntau tus neeg mob, ntau tus kws tshaj lij hais tias. Tsis tas li ntawd, nws tsuas yog siv tau rau hauv cov ntawv me me ntawm kev ntxhov siab,nervousness, nce excitability. Yog tias tus neeg mob muaj kev nyuaj siab loj, cov tshuaj no yuav tsis pab nws.
Puas muaj analogues?
Qhia txog cov khoom tseem ceeb ntawm cov tshuaj "Afobazol" cov lus qhia rau kev siv. Cov ntsiav tshuaj Analogue yuav tsum muaj cov tshuaj fabomotizol ua haujlwm, tab sis tsis muaj cov tshuaj no hauv cov khw muag tshuaj, tshwj tsis yog cov tshuaj tau teev tseg. Muaj cov tshuaj uas muaj txiaj ntsig zoo sib xws thiab tseem muag yam tsis muaj kws kho mob sau ntawv. Cov no suav nrog Tenoten, NovoPassit, Persen. Yog tias tus kws kho mob tau sau cov tshuaj tranquilizer rau kev siv, uas ib qho derivative ntawm diazepine series nkag mus rau hauv cov khoom xyaw, ces yuav tsum tau yuav cov tshuaj nruj me ntsis. Cov no yog cov tshuaj xws li Adaptol, Sibazon, Relanium thiab ntau lwm yam.
Ib yam tshuaj tsis yog tshuaj niaj hnub uas pab tib neeg ua kom lawv tus mob nyob rau hauv qhov xwm txheej ntxhov siab, nce kev ntxhov siab, yog Afobazol ntsiav tshuaj. Cov lus qhia rau kev siv qhia tias lawv muaj cov khoom xws li fabomotizol. Hmoov tsis zoo, tsis muaj kev sim tshuaj ntsuam xyuas tau ua tiav rau cov tshuaj no, thiab yog li cov ntaub ntawv pov thawj rau nws qhov kev ua tau zoo tsis txaus los txiav txim siab tias nws muaj txiaj ntsig zoo rau kev sau tshuaj raws li kev xaiv thawj zaug.
