Hyperprolactinemia - yog dab tsi? Hyperprolactinemia tshwm sim li cas? Kev kho mob

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Hyperprolactinemia - yog dab tsi? Hyperprolactinemia tshwm sim li cas? Kev kho mob
Hyperprolactinemia - yog dab tsi? Hyperprolactinemia tshwm sim li cas? Kev kho mob

Video: Hyperprolactinemia - yog dab tsi? Hyperprolactinemia tshwm sim li cas? Kev kho mob

Video: Hyperprolactinemia - yog dab tsi? Hyperprolactinemia tshwm sim li cas? Kev kho mob
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Anonim

Hauv tshuaj, muaj lub tswv yim ntawm "hyperprolactinemia". Nws yog dab tsi thiab yuav ua li cas nws manifests nws tus kheej, tsis yog txhua tus paub. Tab sis nyob rau hauv xyoo tas los no, qhov kev kuaj mob no tau ua ntau thiab ntau zaus. Yog li ntawd, nws yog ib qho tseem ceeb kom paub cov tsos mob ntawm tus kab mob no, txoj kev kho mob, nrog rau cov teeb meem tshwm sim, thiaj li tsis txhob nco lub sijhawm thiab hu rau tus kws kho mob tshwj xeeb hauv lub sijhawm.

Dab tsi yog hyperprolactinemia
Dab tsi yog hyperprolactinemia

Tus yam ntxwv ntawm tus kab mob

Hyperprolactinemia - nws yog dab tsi, nws tshwm sim li cas, nws kho li cas? Lo lus nug no tshwm sim hauv cov neeg uas hnov cov lus txhais li no thawj zaug. Hyperprolactinemia yog ib yam mob tshwm sim los ntawm kev nce qib ntawm cov tshuaj hormone prolactin hauv cov ntshav. Prolactin yog tsim los ntawm cov qog endocrine ntawm lub qog pituitary, uas yog suav tias yog "tus thawj coj" ntawm kev ua haujlwm puv ntoob ntawm endocrine system. Nws yog nws lub luag haujlwm los tswj kev ua haujlwm ntawm:

  • thyroid;
  • qe thiab zes qe;
  • adrenals.

Lub luag haujlwm ntawm lub caj pas pituitary nyob rau hauv qhov tseeb tias, ntxiv rauprolactin, tsim cov tshuaj hormones LH thiab FSH.

hyperprolactinemia hauv cov poj niam
hyperprolactinemia hauv cov poj niam

YLub luag haujlwm ntawm prolactin hauv lub cev

Cov tshuaj hormone no yog lub luag haujlwm rau kev yug me nyuam. Prolactin txhawb kev loj hlob thiab kev loj hlob ntawm cov qog mammary. Nws lub luag haujlwm tseem ceeb yog los txhawb kev tsim cov mis nyuj hauv tus poj niam uas tau yug los. Nyob rau hauv lub cev ntawm ib tug txiv neej, cov tshuaj no yog tsim nyob rau hauv me me.

Prolactin ua ke nrog lwm cov tshuaj hormones (LH, FSH) hauv tus poj niam lub cev txhawb kev tsim cov tshuaj estrogen, uas yog lub luag haujlwm rau kev loj hlob ntawm lub qe. Kev ruaj ntseg ntawm kev coj khaub ncaws, qhov tshwm sim ntawm conception nyob ntawm lawv. Yog hais tias peb tham txog cov txiv neej, ces ua tsaug rau cov tshuaj hormones, testosterone yog tsim. Txawm tias phev motility nyob ntawm prolactin.

Cov tsos mob ntawm hyperprolactinemia
Cov tsos mob ntawm hyperprolactinemia

Kev faib tawm

Nyob ntawm cov xwm txheej uas ua rau muaj kev loj hlob ntawm hyperprolactinemia, hauv cov tshuaj nws yog txoj cai los faib cov xwm txheej no rau hauv hom:

1. Physiological. Prolactin qib nce vim yog cov txheej txheem ib txwm nyob hauv tib neeg lub cev. Kev kuaj mob hauv cov menyuam mos, cev xeeb tub thiab lactating poj niam.

2. Pathological. Yog vim li cas nyob rau hauv ib tug tej yam pathology. Tab sis, raws li kev xyaum qhia, cov qog pituitary feem ntau ua rau hyperprolactinemia.

3. Pharmacological. Tus mob no cuam tshuam nrog kev noj tshuaj, tshuaj.

4. Idiopathic. Cov tshuaj hormones nce siab vim tsis paub yog vim li cas.

Pathogenesis

Physiological hyperprolactinemia tshwm sim los ntawm cov txheej txheem ntuj tsimtshwm sim nyob rau hauv tib neeg lub cev txhua hnub. Nws provoked:

1. Lub sijhawm cev xeeb tub. Hauv cov poj niam, ze rau 7 lub lis piam ntawm cev xeeb tub, qib ntawm prolactin nce. Cov txheej txheem no txuas ntxiv mus rau tag nrho 9 lub hlis, tab sis tom qab yug me nyuam (tom qab 1-2 lub hlis), txhua qhov ntsuas rov qab mus rau qhov qub.

Cov tsos mob hyperprolactinemia hauv cov poj niam
Cov tsos mob hyperprolactinemia hauv cov poj niam

2. Npau suav. Thaum ib tug neeg tsaug zog, tom qab ib teev, theem ntawm prolactin hauv nws cov ntshav nce, tab sis tom qab sawv los, nws poob qis heev.

3. Kev ntxhov siab. Kev ntxhov siab yog qhov ua rau muaj kev cuam tshuam hauv lub cev, suav nrog kev tso tawm ntau cov tshuaj hormones. Hauv qhov xwm txheej ntawm prolactin, qhov xwm txheej ntxhov siab yuav tsum tau nrog los ntawm kev txo qis hauv cov ntshav siab, ua tsis taus pa.

4. Physiological hyperprolactinemia hauv cov poj niam tshwm sim thaum muaj kev sib deev, kev khaus ntawm lub caj pas mammary (tshwj xeeb tshaj yog thaum pub niam mis).

5. Noj zaub mov protein.

6. Txhua yam cuam tshuam rau lub cev uas ua rau mob.

Pathological hyperprolactinemia yog provoked los ntawm:

1. Cov kab mob ntawm hypothalamus, pituitary caj pas (xws li feem ntau ua rau hom no).

2. Hormonal ntshawv siab.

3. Tau txais kev raug mob hauv siab.

4. Nquag curettage ntawm uterine kab noj hniav.

5. Polycystic zes qe menyuam syndrome.

6. Teeb meem mob siab.

7. Lub raum tsis ua haujlwm.

8. Lupus erythematosus.

Pharmacological tshwm sim vim noj:

  • tshuaj tiv thaiv kev nyuaj siab;
  • Ycontraceptives;
  • tshuaj tiv thaiv hypertensive;
  • neuroleptics.

Signs

Hyperprolactinemia hauv cov txiv neej manifests nws tus kheej raws li hauv qab no:

  • txo qis zog;
  • lactorrhea (kua kua mis los yog mis nyuj ntawm lub txiv mis);
  • psycho-emotional instability;
  • kev muaj menyuam;
  • osteoporosis;
  • obese;
  • txo qis qhov hnyav ntawm cov yam ntxwv sib deev thib ob.

YHyperprolactinemia tshwm sim nws tus kheej txawv ntawm txhua tus. Cov tsos mob hauv poj niam:

  • menstrual irregularity;
  • galactorrhea;
  • kev muaj menyuam;
  • txo qis libido;
  • tsis xis nyob thaum muaj kev sib deev tshwm sim los ntawm kev tsis muaj roj;
  • anorgasmia;
  • pob txuv;
  • seborrhea ntawm tawv taub hau;
  • apoplexy;
  • ib tug poj niam tau txais cov yam ntxwv ntawm txiv neej, nws cov clitoris hypertrophies, plaub hau loj hlob thoob plaws nws lub cev.
Kev kho mob hyperprolactinemia
Kev kho mob hyperprolactinemia

Dab tsi yog qhov tshwj xeeb ntawm hyperprolactinemia? Cov tsos mob tuaj yeem yog ib leeg thiab ua ke nrog ib leeg. Qhov kev siv ntawm cov paib kuj txawv. Piv txwv li, galactorrhea, uas tshwm sim nyob rau hauv 80% ntawm cov poj niam uas muaj hyperprolactinemia, manifests nws tus kheej raws li ib tug me ntsis tawm ntawm lub txiv mis nrog mob siab rau hauv ib co neeg mob, thaum nyob rau hauv lwm tus neeg nws provokes ib tug sudden copious tawm.

Kev puas siab puas ntsws tshwm sim

Hyperprolactinemia syndrome (lwm lub npe rau tus mob no) ua rau insomnia thiab nco teeb meem nyob rau hauv ib tug neeg. Lub peev xwm ua haujlwm tau raug txo qis, txawm tias tsis muaj qhov laj thawj pom rau qhov no. Lwm tuskev puas siab puas ntsws yog:

  • kev ntxhov siab thiab ntshai;
  • Nyob zoo ib tsoom phooj ywg;

  • chim siab;
  • psychosis (qee zaum cov xwm txheej no tseem ceeb, xav tau kev pab tshwj xeeb tam sim);
  • muaj tsawg zaus, "mob siab" (qhov hu ua qhov mob tshwm sim hauv lub hauv siab yam tsis muaj lub hauv paus organic).

Cov me nyuam

Qee zaum tus menyuam raug kuaj pom tias muaj hyperprolactinemia. Qhov no tej zaum yuav ua rau yav tom ntej? Yog peb tham txog ib tug hluas nkauj ces thaum hluas nws yuav muaj kev ua txhaum thaum hluas.

Ob tug tub thiab ntxhais ntsib teeb meem nrog pob txha tsim. Cov pob txha yuav qaug zog thiab nkig.

Examination

Kev kuaj mob hyperprolactinemia xav tau dab tsi? Cov laj thawj uas tau teev tseg yuav tsum muaj cov kev kuaj mob hauv qab no:

  • kuaj ntshav rau qib prolactin;
  • kev tshuaj ntsuam cov zis thiab ntshav;
  • skeletal scintigraphy;
  • YProstate ultrasound;
  • hauv cov poj niam ultrasound ntawm lub mis, zes qe menyuam, uterus;
  • X-ray pob txha taub hau;
  • CT;
  • MRI.

Nrog rau kev kuaj ntshav rau qib prolactin, koj yuav tsum tau ceev faj heev. Rau qhov tseeb ntawm cov ntsuas, nws raug coj los ntawm 5-8 hnub ntawm kev coj khaub ncaws. Tsis yog ib qho kev ntsuam xyuas txaus los ua qhov kev kuaj mob. Hyperprolactinemia hauv cov poj niam feem ntau ua haujlwm tau zoo, yog li nws raug pom zoo kom siv qhov kev tshuaj xyuas no 3 zaug.

Kev kho mob

Pharmacological hyperprolactinemia tsis ua rau muaj teeb meem tshwj xeeb. Kev kho mob yogtsuas yog nyob rau hauv abolition ntawm cov tshuaj (los yog nws hloov), uas ua rau ua txhaum cai. Prolactin qib rov qab mus rau qhov qub nyob rau lub sijhawm luv luv. Yog tias peb tham txog daim ntawv physiological, ces nws tsis tas yuav muaj kev cuam tshuam.

Tshuaj Kho Mob

tshuaj Dopaminomimetic yog lub hauv paus rau kev kho mob ntawm hyperprolactinemia. Lawv ua rau cov qog uas provoked qhov kev cuam tshuam, txo nws. Qee lub sij hawm nws tshwm sim tias cov tshuaj pab kom tshem tawm tag nrho. Tom qab ntawd, qib ntawm prolactin hauv cov ntshav rov qab mus rau qhov qub.

hyperprolactinemia hauv cov txiv neej
hyperprolactinemia hauv cov txiv neej

Hypothyroidism yuav tsum siv cov thyroid hormones. Yog tias tus neeg mob muaj cov tshuaj hormonal, tus kws kho mob sau cov tshuaj hormonal tsim nyog.

Kev ua haujlwm

Kev phais yog qhia hauv cov xwm txheej hauv qab no:

  • apoplexy;
  • thaum tshuaj kho tsis pab lossis tus neeg mob tsis haum cov tshuaj tsim nyog;
  • deterioration ntawm neuralgia.

Kev ua haujlwm tsis tas yuav muab qhov xav tau. Tom qab nws, hyperprolactinemia rov qab nyob rau hauv ib nrab ntawm cov mob. Tus neeg mob tseem muaj kev pheej hmoo ntawm cov teeb meem:

  • thaum lub sijhawm ua haujlwm, lub paj hlwb optic, pituitary stalk lossis hypothalamus puas lawm;
  • ib lub hlwb hemorrhage yuav tshwm sim.

Kev kho hluav taws xob

Kev kho mob no tsuas yog siv rau qhov mob hnyav xwb. Kev kho hluav taws xob yuav siv sij hawm ntau thiab yuav tsum tau ua siab ntev los ntawm tus neeg mob, vim tias cov txheej txheem tuaj yeem siv sijhawm ib xyoos thiab ib nrab. Tom qab txoj kev kho no, ib tus neeg tuaj yeem tau txais cov hemorrhage hauvpaj hlwb, hluav taws xob puas tsuaj rau cov hlab ntsha, thiab lub hlwb necrosis.

Txoj kev ua neeg

Qee tus kws kho mob pom zoo kom lawv cov neeg mob siv cov zaub mov txawv. Tab sis qhov no tshwm sim tsuas yog tom qab qhov ua rau ntawm tus mob no tau tsim.

Txoj kev nrov:

  • haus mint thiab chamomile tshuaj yej ob peb zaug ib hnub;
  • rau kev ruaj ntseg ntawm lub siab lub ntsws, nws yog ib qho tsim nyog yuav tau siv valerian, motherwort, hawthorn, St. John's wort (tuaj yeem nrhiav tau hauv khw muag tshuaj).

Txoj kev Folk raug pom zoo ua ntxiv rau kev kho tshuaj tseem ceeb.

Kev nyuaj siab

Hyperprolactinemia, cov tsos mob uas tsis tau muab coj los siv rau lub sijhawm ntev, ua rau mastopathy lossis malignant neoplasm hauv qog mammary. Tus poj niam kuj muaj kev pheej hmoo ntawm uterine hypoplasia.

hyperprolactinemia cuam tshuam li cas rau cov metabolism? Lub xeev no ua li cas rau cov metabolism? Raws li nws hloov tawm, nce qib prolactin tuaj yeem ua rau:

  • mob ntshav siab;
  • IHD;
  • osteoporosis;
  • urolithiasis;
  • diabetes.

Kev Tiv Thaiv

ua rau hyperprolactinemia
ua rau hyperprolactinemia

Tsis muaj qhov qhia tseeb uas yuav pab tiv thaiv hyperprolactinemia. Ib tug neeg yuav tsum tsis txhob muaj kev ntxhov siab, so kom txaus. Lub luag haujlwm tseem ceeb yog ua los ntawm kev noj zaub mov kom zoo, kev ua si lub cev (ua si kis las, taug kev tsis tu ncua). Nws yog ib qho tsim nyog yuav tsum tso tus cwj pwm phem - cawv thiab haus luam yeeb. Kas fes thiab tshuaj yej muaj zogNws yog qhov tsis tsim nyog siv nrog kev kuaj mob ntawm "hyperprolactinemia".

Cov tsos mob ntawm cov poj niam, xws li cov kua mis tawm ntawm lub txiv mis sab nraud ntawm cev xeeb tub, kev coj khaub ncaws tsis zoo, tsis tas yuav ceeb thiab dhau los ua qhov laj thawj rau kev sab laj kws kho mob. Tab sis qhov no tsis yog lawm! Tom qab tag nrho, cov cim qhia tau hais tias muaj kev ua txhaum cai hauv lub cev uas tsis tuaj yeem tsis quav ntsej. Qhov no kuj siv tau rau cov txiv neej. Yog li ntawd, koj yuav tsum tau ceev faj ntxiv txog koj txoj kev noj qab haus huv thiab tsis txhob hnov qab tias txhua yam kev ua txhaum cai raug cai los ntawm qee yam thiab tuaj yeem ua rau muaj teeb meem txaus ntshai.

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