Kev piav qhia ntawm Sheehan's syndrome: kuaj mob, tsos mob, kho

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Kev piav qhia ntawm Sheehan's syndrome: kuaj mob, tsos mob, kho
Kev piav qhia ntawm Sheehan's syndrome: kuaj mob, tsos mob, kho

Video: Kev piav qhia ntawm Sheehan's syndrome: kuaj mob, tsos mob, kho

Video: Kev piav qhia ntawm Sheehan's syndrome: kuaj mob, tsos mob, kho
Video: Tshuaj theem vim li cas thiaj tau nqi ?/ Siv kho mob dab tsi?/paris polyphylla use for? 2024, Kaum ib hlis
Anonim

Peb txhua tus muaj kev ntxhov siab thiab kev cia siab tos txog kev yug menyuam. Peb ntseeg siab tias tus me nyuam thiab leej niam yuav noj qab nyob zoo, thiab tej yam txaus ntshai xws li Sheehan thiab Denny-Morfan, Down lossis Simmonds syndromes yuav tsis raug kuaj pom hauv lawv. Tag nrho cov kab mob no txaus ntshai thiab nyuaj kho. Hauv tsab xov xwm no, peb yuav piav qhia ntxaws txog thawj ntawm lawv - Sheehan's syndrome. Nws cuam tshuam rau qee tus poj niam hauv kev ua haujlwm.

Kev piav qhia

Postpartum necrosis ntawm lub caj pas pituitary kuj hu ua Sheehan's syndrome. Cov keeb kwm kev kho mob qhia tau hais tias qhov no yog ib tug complex pathology uas tsim tom qab ib tug nyuaj thiab ntev yug. Qhov ua rau yog los ntshav ntau, uas, dhau los, ua rau cov hlab ntsha hypotension. Raws li qhov tshwm sim ntawm nws txoj kev loj hlob, lub qog pituitary, ib lub qog me me hauv lub hlwb, muaj cov ntshav tsawg, uas yog lub luag haujlwm rau kev ua haujlwm ntawm tib neeg endocrine system thiab tsim cov tshuaj hormones. Sheehan's syndrome tshwm sim hauv lub cev, qhov tshwm sim ntawm qhov tsis zoo siab tshaj plaws - koj yuav tsis muaj peev xwm pub niam mis rau menyuam, tab sis qhov no tsuas yog qhov tsawg tshaj plaws ntawm cov teeb meem uas tos niam.

Sheehan Syndrome
Sheehan Syndrome

Vim tias cov kab mob tuaj yeem ua tiav hauv daim ntawv tshem tawm, nws qhov tseeb zaus tsis paub. Nws tau tsim tias tom qab yug los los ntshav, qhov kev pheej hmoo ntawm nws txoj kev loj hlob mus txog 40%. Tus kab mob no tau kuaj pom hauv txhua tus poj niam thib plaub yog tias nws poob txog 800 ml ntawm cov ntshav, hauv 50% ntawm cov neeg yug menyuam - nrog rau qhov poob ntawm ib liter ntawm cov kua dej tseem ceeb.

Symptoms

Lawv yog qhov tshwj xeeb. Piv txwv li, thawj zaug hu xov tooj yuav tsum yog qhov kev tso cai ntawm lactation. Cov tsos mob me me ntawm Sheehan's syndrome feem ntau tsis tshwm sim txog li ob peb lub hlis tom qab. Feem ntau qhov no yog theem nrab amenorrhea - qhov tsis ua tiav ntawm kev coj khaub ncaws thiab txo qis hauv kev tso tawm ntawm gonadotropins. Tom qab ntawd hypothyroidism raug kuaj pom, thaum cov thyroid caj pas tsim cov tshuaj hormones tsis txaus. Tawm tsam keeb kwm yav dhau los no, myxedema tsim - ua txhaum ntawm cov metabolism hauv cov protein, uas ua rau cov ntaub so ntswg o hnyav.

Sheehan Syndrome Case History
Sheehan Syndrome Case History

Cov poj niam hauv lawv cov thawj coj - 20 mus rau 40 xyoo - kuj tuaj yeem ntsib hypopituitarism. Qhov no yog ib qho mob hnyav ntawm lub cev, uas raug kev txom nyem los ntawm kev tsis txaus ntawm ntau yam tshuaj hormones: ib tug poj niam muaj zog tsis muaj zog, poob ceeb thawj, tsis muaj libido. Hauv cov xwm txheej siab, tus neeg yuav raug mob los ntawm cov kab mob neuropsychiatric thiab txawm tias poob rau hauv lub coma.

Kev faib tawm

Tsis muaj cov tshuaj hormones hauv lub cev tuaj yeem sib txawv - los ntawm qhov mob me mus rau qhov tsis txaus. Raws li qhov no, cov nram qab no hom ntawm Sheehan's syndrome yog txawv:

  1. Daim ntawv thoob ntiaj teb. Nrog rau nws, muaj qhov tsis txaus ntawm cov tshuaj hormones sab saum toj, vim tias qhov kev puas siab puas ntsws loj tuaj, lub paj hlwb ua haujlwm tsis zoo, tus neeg poob rau hauv coma.
  2. Ib nrab daim ntawv. Hormone deficiency tsis tau hais ntau, yog li ntawd, tsuas yog tsis txaus ntawm adrenocorticotropic, gonadotropic lossis thyrotropic kev ua haujlwm raug kuaj pom. Qhov chaw mos, ua haujlwm ntawm lub raum thiab lwm yam kabmob raug kev txom nyem.
  3. daim ntawv sib xyaw. Thaum tag nrho cov haujlwm saum toj no raug ua txhaum tib lub sijhawm.
Sheehan syndrome cov tsos mob
Sheehan syndrome cov tsos mob

Pom pom txawm tias qhov tshwm sim me me ntawm tus kab mob, koj yuav tsum tau hu rau tus kws kho mob gynecologist tam sim lossis tus kws kho mob hauv zos uas yuav xa koj mus rau qhov kev sim tsim nyog thiab teem caij sab laj nrog lwm tus kws tshaj lij.

Pathogenesis

Qhov no yog ib txoj hauv kev los ntawm qhov pib ntawm tus kab mob mus rau qhov pom tseeb ntawm cov tsos mob. Cov kws kho mob paub txog nws nyob rau ntau theem: los ntawm cov kab mob molecular mus rau kev cuam tshuam ntawm lub cev tag nrho. Nws yog ib qho tsim nyog yuav tau kawm nws, txij li nws yog lub pathogenesis uas muab cov lus teb rau lo lus nug ntawm yuav ua li cas thiab yog vim li cas tus kab mob no tshwm sim. Raws li rau Sheehan's syndrome, nws tau ntev tau tsim los tias nws qhov kev tshwm sim tseem ceeb yog kev hloov pauv hauv cov qog pituitary. Lawv tshwm sim tawm tsam keeb kwm ntawm cov ntshav coagulation, thaum muaj spasm ntawm cov hlab ntsha ntawm lub anterior pituitary caj pas tom qab cov ntshav poob hnyav.

Sheehan Syndrome kev kho mob
Sheehan Syndrome kev kho mob

Sheehan's syndrome, cov tsos mob uas tau piav qhia saum toj no, kuj tuaj yeem tshwm sim tom qab rho menyuam, nrog rau kev tawm tsam keeb kwm ntawm cov kab mob tshwm sim tom qab yug menyuam. Ib qho tseem ceeb tshaj plaws yog preeclampsia - ib qho teeb meem ntawm cev xeeb tub, thaum yav tom ntej niam tau kuaj pom tias muaj mob hnyav, tsis muaj protein ntau hauv cov zis, ntshav siab, thiab lwm yam. Nws yog cov poj niam no uas ua rau ntshav txhaws.

daim duab kho mob

Qib ntawm kev tshwm sim ntawm Sheehan's syndrome sib txawv. Feem ntau cov kws kho mob paub qhov txawv ntawm cov ntawv no:

  • Easy. Nws yog tus cwj pwm los ntawm kev qaug zog thiab mob taub hau tsis tu ncua. Muaj qhov txo qis hauv kev ua haujlwm ntawm cov qog adrenal thiab cov thyroid caj pas.
  • Average. Cov kab mob saum toj no tseem cuam tshuam ntau dua. Piv txwv li, ib tug poj niam xav tias nkees heev, nws cov ntsia hlau tawg, nws yuav ua rau qaug zog. Kev ua haujlwm ntawm zes qe menyuam raug cuam tshuam, qee zaum mus txog ovulatory infertility.
  • Hav. Qhov chaw mos thiab cov qog mammary hypertrophy, ib tug neeg raug kev txom nyem los ntawm qaug zog, baldness, daim tawv nqaij pigmentation, thiab nco tsis tau. Lub cev hnyav poob rau tom qab ntawm qhov mob hnyav.

Tus mob no yog tus yam ntxwv los ntawm kev mob ntshav qab zib hnyav, uas tshwm sim nws tus kheej hauv txhua hom kab mob. Nws yog heev resistant rau kev kho mob, yog li nws yog xyaum tsis amenable rau kev kho mob. Cov kws kho mob yuav tsum sim kho cov qib hlau hauv cov ntshav.

Diagnosis

Thaum nws, nws yog ib qho tseem ceeb uas yuav tsum tau kawm kom ntxaws txog tus yam ntxwv anamnesis, qhov twg muaj kev sib txuas ntawm tus kab mob thiab los ntshav los yog septic shock thaum lub sijhawm rho menyuam dhau los lossis yug menyuam. Txhawm rau txiav txim siab Sheehan's syndrome, kev kuaj mob pib nrog kev kuaj mob ntawm cov qog mammary: lawv tsis nce qhov loj me, tsis txhob thicken, mis nyuj tsis tso tawm txawm tias muaj zog siab thiab tom qab kev zaws.

Sheehan thiab Danny morphan syndromes
Sheehan thiab Danny morphan syndromes

Tib lub sijhawm, kuaj ntshav hauv chav kuaj, uas txiav txim siab txog keeb kwm hormonal ntawm lub cev. Nyob ntawm seb qhov ntau npaum li cas ntawm cov tshuaj hormones, kev kuaj mob yog tsim. Coj ib qho qauv thiab tso zis - nws kuj qhia tau tias muaj kev hloov hauv lub cev. Tsis tas li ntawd, cov kws kho mob kuj ua cov kev kuaj mob sib txawv - ib yam dab tsi uas pab kom paub qhov txawv ntawm ib tus kab mob los ntawm lwm tus. Tom qab tag nrho, ntau ntawm lawv muaj cov tsos mob zoo sib xws. Yog li ntawd, txhua tus ntawm lawv tau txheeb xyuas kom meej, sib piv thiab qhov tseeb xaus yog kos.

Kev kho mob

Yuav ua li cas thiaj tshem tau tus kab mob insidious. Feem ntau, thaum ib tus neeg raug kuaj pom tias muaj Sheehan's syndrome, kev kho mob pib nrog cov tshuaj hormones: kev sib deev thiab gonadotropic, thiab kev kho rau kev sib deev infantilism kuj tau sau tseg. Tsim nyog, piv txwv li, "Infecundin" los yog lwm yam tshuaj los ntawm ib tug series ntawm hluavtaws progestins. Cov chav kawm Sinestrol, uas kav ntev li ib hlis, kuj yuav ua tau zoo, nrog rau kev kho mob cyclic rau tag nrho peb lub hlis twg.

Sheehan Syndrome Diagnosis
Sheehan Syndrome Diagnosis

Nco ntsoov tias tsis muaj lus nug txog kev kho tus kheej! Nyob rau hauv tsev, koj tsuas yuav ua mob, provoke kev loj hlob ntawm cov teeb meem loj. Yog li ntawd, thawj cov tsos mob, hu rau tus kws kho mob tam sim ntawd. Tsuas yog kev kuaj mob muaj peev xwm, txoj hauv kev tshaj lij thiab kev kho mob zoo yuav pab kho Sheehan's syndrome thiab tshem tawm cov txiaj ntsig uas nws txoj kev loj hlob hauv lub cev tau ua rau.

Pom zoo: