Cov txheej txheem mob hauv cov ntaub so ntswg, pob qij txha thiab cov pob txha pob txha feem ntau tshwm sim lawv tus kheej li qhov mob, uas tuaj yeem tiv nrog kev pab ntawm ntau yam tshuaj. Cov tshuaj "Melbek", cov lus qhia uas yuav tau piav qhia nyob rau hauv tsab xov xwm no, yog cov tshuaj uas tsis yog-steroidal anti-inflammatory tshuaj uas tsis tsuas yog tshem tawm qhov mob, tab sis kuj txo qhov mob ntawm cov ntaub so ntswg. Txoj kev kho no ua haujlwm li cas? Daim ntawv npaum li cas ntawm cov tshuaj tuaj yeem pom hauv khw muag tshuaj thiab yuav siv li cas? Cia peb kawm paub txog tam sim no.
Tso tawm daim ntawv, muaj pes tsawg leeg
Cov lus qhia piav qhia txog cov tshuaj "Melbek" ua cov tshuaj tiv thaiv kab mob thiab tshuaj tua kab mob. Cov tshuaj muaj nyob rau hauv cov ntsiav tshuaj thiab raws li ib qho kev daws rau kev txhaj tshuaj. Ob daim ntawv noj tshuaj muaj tib yam tshuaj nquag - meloxicam. Nws cov tshuaj muaj 15 mg, hauv cov ntsiav tshuaj "Melbek Forte" - tib tus nqi. Lub ntim me me ntawm cov tshuaj no muaj nyob hauv Melbek ntsiav tshuaj - 7.5 mg.
Cov tshuaj ntxiv uas yog ib feem ntawm cov tshuaj rau kev tswj hwm qhov ncauj tau suav nrog hauv cov npe txheej txheem ntawm cov khoom uas tso cai rau meloxicam.tsis hloov mus cuag lub plab thiab cov hnyuv. Cov no yog lactose, magnesium stearate, aerosil, sodium citrate thiab povidone. Kev daws rau kev txhaj tshuaj, ntxiv rau meloxicam, muaj dej, sodium chloride thiab sodium hydroxide, glycofurfural thiab glycine.
Description of dosage forms
ntsiav tshuaj "Melbek" cov lus qhia piav qhia raws li hauv qab no: puag ncig lub teeb daj nrog kev pheej hmoo ntawm ib qho ntawm qhov chaw. Tib daim ntawv ntau npaum li cas, tab sis nrog cov ntsiab lus siab ntawm cov tshuaj nquag ("Melbek Forte") zoo ib yam, nrog rau qhov sib txawv tsuas yog tias ob qho kev pheej hmoo ntawm tus ntoo khaub lig raug siv rau cov ntsiav tshuaj. Ob hom ntsiav tshuaj tau ntim rau hauv hlwv ntawm 10 daim txhua.
Cov lus qhia piav qhia txog cov tshuaj rau kev txhaj tshuaj raws li cov kua ntshiab daj uas tsis muaj cov khoom txawv teb chaws suav nrog. Nws yog poured rau hauv pob tshab iav ampoules ntawm 1.5 ml txhua. Ib pob muaj tsis pub ntau tshaj 3 ampoules nrog cov tshuaj.
Pharmacological action
Ib yam ntawm cov khoom xyaw nquag ntawm cov tshuaj "Melbek" cov lus qhia hu lub peev xwm los ua lub chaw ntawm kev sib txuas ntawm prostaglandins ntawm qib thib ob (COX-2), thaum xyaum tsis cuam tshuam rau COX-1. Yog li, cov tshuaj siv tau tsis ua rau muaj kev cuam tshuam tsis zoo los ntawm lub plab zom mov ntawm cov neeg mob.
Tsawg kawg 89% ntawm cov khoom nquag tau nqus los ntawm txoj hnyuv. Ib qib ruaj khov ntawm meloxicam tau pom peb hnub tom qab pib kho nrog Melbek. Cov lus qhia rau kev siv kuj muaj cov ntaub ntawv uas nrog ntevkev kho mob nrog tshuaj (txawm tias ntau tshaj 1 xyoos), tsis muaj kev cuam tshuam ntawm cov khoom nquag thiab lawv cov metabolites hauv cov ntaub so ntswg.
Raws li qhov tshwm sim ntawm cov metabolism, meloxicam yuav luag tag nrho decomposes rau qhov yooj yim tshaj plaws inactive tshuaj uas tau tawm ntawm lub cev nyob rau hauv ib hnub, ntau tshaj ob. Lawv ib nrab lub neej yog 20 teev.
Kev qhia
ntsiav tshuaj "Melbek" thiab "Melbek Forte" cov lus qhia rau kev siv tshuaj noj rau cov kab mob hauv qab no:
- mob caj dab rheumatoid (raws li kev kho mob);
- osteoarthritis, arthrosis thiab lwm yam kab mob degenerative ntawm articular apparatus (raws li tshuaj loog);
- myalgia, dorsalgia, lumbago thiab sciatica.
Tsis tas li ntawd, cov tshuaj tau ua tiav zoo tiv thaiv kev mob hniav, cov leeg thiab mob taub hau, thiab tseem ua rau cov neeg mob nyob rau lub sijhawm tom qab phais lossis raug mob.
Nyob rau tib lub sijhawm, nws raug nquahu kom siv cov tshuaj Melbek. Cov lus qhia txhaj tshuaj, tshuaj xyuas ntawm cov kws kho mob thiab cov neeg mob tau pom tias muaj txiaj ntsig zoo rau qhov mob ntawm txhua lub hauv paus chiv keeb, txawm li cas los xij, muaj qee yam ntawm lawv siv. Peb yuav tham txog qhov no me ntsis tom qab, nyob rau hauv nqe lus ntawm cov tshuaj "Melbek".
Tshuaj noj thiab kev tswj hwm
Kev siv tshuaj "Melbek" cov lus qhia rau kev siv pom zoo li cas? Cov ntsiav tshuaj ntawm koob tshuaj 7.5 mg yog qhia rau kev kho mob ntawm qhov mobo ntawm cov pob qij txha nrog degenerative dynamics. Tus naj npawb ntawm cov ntsiav tshuaj ib hnub yuav tsum tsis txhob ntau tshaj 1 daim. Tsuas yog nrog kev mob hnyav zuj zus tuaj yeem tuaj yeem nce qhov koob tshuaj txhua hnub rau 15 mg.
Nyob rau hauv rheumatoid mob caj dab thaum pib ntawm kev kho mob, koob tshuaj txhua hnub yog 15 mg. Tom qab tus neeg mob tus mob stabilizes, nws raug txo los ntawm ib nrab, mus rau 7.5 mg ib hnub twg.
ntsiav tshuaj "Melbek" cov lus qhia pom zoo haus dej kom txaus, qhov zoo tshaj plaws nrog dej. Kev noj zaub mov tsis cuam tshuam rau kev nqus ntawm cov tshuaj nquag. Txawm li cas los xij, cov kws tshaj lij qhia kom noj cov ntsiav tshuaj tom qab noj mov. Ua li no, kev khaus khaus ntawm lub plab tuaj yeem zam tau.
Cov lus qhia rau kev siv hais li cas txog txoj kev siv cov tshuaj Melbek? Kev txhaj tshuaj yuav tsum tau muab tsuas yog thawj hnub ntawm kev kho mob. Tom qab cov nyhuv analgesic ntawm cov tshuaj tau ruaj khov, nws yog ib qho tsim nyog los hloov daim ntawv no rau qhov ncauj. Yuav kom ua tiav cov txiaj ntsig zoo, nws yog ib qho tseem ceeb uas cov tshuaj nkag mus rau hauv cov txheej txheem tob tshaj plaws ntawm cov leeg.
Qhov siab tshaj plaws txhua hnub ntawm daim ntawv no yog, xws li hauv cov ntsiav tshuaj, 15 mg.
kev tawm tsam tsis zoo
Cov kev mob tshwm sim thaum noj Melbek yog suav tias yog ib qho tseem ceeb rau txhua yam tshuaj uas koom nrog pawg ntawm cov tshuaj uas tsis yog-steroidal anti-inflammatory. Lawv yog tus cwj pwm los ntawm kev cuam tshuam ncaj qha rau ntawm daim nyias nyias ntawm lub plab thiab lub plab zom mov tag nrho. Yog li cov kev xav tsis zoo tshaj plaws hauv kev kho mob nrog cov tshuaj "Melbek" hauv daim ntawv ntawm dyspeptic.mob, xeev siab, ntuav, mob plab thiab flatulence. Kev ua kom muaj zog ntawm cov tsos mob no mus txog rau qhov mob plab hnyuv tshwm sim thaum tsis ua raws li cov lus pom zoo los ntawm cov lus qhia.
Ntawm cov kev mob tshwm sim hauv kev kho mob nrog Melbek thiab Melbek Forte, cov lus qhia hais txog kev tsis sib haum xeeb hauv hematopoietic system, hauv nruab nrab paj hlwb, cov kab mob hauv nruab nrog cev thiab ua pa. Tsis tas li ntawd, cov tshuaj hauv qee kis tuaj yeem ua rau muaj kev nce ntshav siab. Tsis tas li ntawd, cov neeg mob yuav hnov mob, palpitations, thiab hnov ntawm cov ntshav khiav mus rau lub taub hau thiab lub ntsej muag.
Qee zaum, muaj qhov tsis zoo ntawm cov tshuaj rau ntawm daim tawv nqaij. Hauv particular, kwv yees li 1% ntawm cov neeg mob raug kev txom nyem photosensitivity thiab ua xua ua pob liab vog. Hauv cov xwm txheej tsawg heev, thaum noj cov tshuaj "Melbek", qhov tshwm sim hnyav tuaj yeem tshwm sim, mus txog qhov poob siab anaphylactic.
YContraindications
Melbek tshuaj tsis raug pom zoo yog tias tus neeg mob yav dhau los tau muaj kev tsis haum tshuaj raws li kev mob hawb pob, angioedema thiab urticaria rau cov tshuaj uas tsis yog-steroidal anti-inflammatory thiab, tshwj xeeb, rau cov tshuaj aspirin. Tsis tas li ntawd, cov ntsiav tshuaj tau muab tshuaj kom zoo rau cov kab mob erosive thiab ulcerative ntawm lub plab thiab duodenum nyob rau theem mob. Tsis tas li ntawd, tsis txhob sau cov tshuaj rau cov neeg uas muaj lub siab tsis zoo thiab lub raum ua haujlwm. Ib qho kev txwv loj yog tus neeg mob hnub nyoog qis dua 15.
Siv thaum cev xeeb tub thiab lactation
NtauCov neeg mob uas mob mob, cov lus nug tshwm sim seb puas siv tshuaj "Melbek" thaum cev xeeb tub raug tso cai. Cov lus qhia rau kev siv, kev txhaj tshuaj thiab cov ntsiav tshuaj, uas tau piav qhia hauv cov ncauj lus kom ntxaws, muaj cov ntaub ntawv hais tias nws yog qhov zoo dua tsis txhob siv ob hom tshuaj thaum lub sijhawm yug menyuam. Qhov tseeb yog tias cov tshuaj nquag ntawm cov tshuaj nkag mus rau hauv cov kua dej synovial thiab kov yeej cov teeb meem placental. Txawm hais tias tsis muaj cov txiaj ntsig teratogenic tau tshawb pom thaum kuaj sim, qhov kev pheej hmoo rau tus menyuam hauv plab tseem siab.
Cov lus qhia tshwj xeeb
Nyob rau hauv ntau cov kab mob thiab cov xwm txheej, nws yuav tsum tau ceev faj heev txog kev siv tshuaj. Qee zaum, nws yuav tsim nyog tshem tawm cov tshuaj "Melbek". Piv txwv li, yog tias muaj kev pheej hmoo los ntshav hauv cov kab mob ntawm lub plab zom mov, cov tshuaj yuav tsum tau txiav kom sai li sai tau. Tib yam siv rau cov neeg mob uas lub raum tsis ua haujlwm, tshwj xeeb nrog cov ntshav qis hauv cov kabmob no. Nrog rau kev txuas ntxiv ntawm kev kho mob nrog cov tshuaj "Melbek", cov lus qhia ceeb toom txog qhov muaj peev xwm ntawm kev mob raum tsis ua haujlwm.
Cov kws tshaj lij tau sau tseg tias lub raum tsis ua haujlwm feem ntau pom nyob rau hauv cov neeg mob cirrhosis ntawm daim siab, congestive plawv tsis ua hauj lwm thiab cov neeg uas, vim concomitant kab mob, raug yuam kom noj diuretics.
Kev kho mob ntev nrog Melbek yog contraindicated rau cov neeg laus.
Ntau tshaj
Thaum tshajpom zoo koob tshuaj, cov neeg mob yuav muaj cov tsos mob zoo ib yam li cov uas tau piav nyob rau hauv nqe lus ntawm kev phiv. Tsis muaj cov tshuaj tshwj xeeb uas tuaj yeem tshem tawm cov tshuaj lom, yog li cov kws tshaj lij pom zoo kom ua plab hnyuv, nrog rau kev noj cov tshuaj absorbents. Tsis tas li ntawd, kev kho cov tsos mob muaj txiaj ntsig zoo. Nyob rau tib lub sijhawm, cov kws kho mob nco ntsoov tias hemodialysis thiab lwm txoj hauv kev tshem tawm cov kua dej hauv lub cev, suav nrog kev ua kom diuresis, tsis txhob muab qhov tshwm sim nrog kev noj ntau dhau ntawm meloxicam. Tib yam uas tuaj yeem pab tshem tawm sai ntawm cov tshuaj no los ntawm lub cev yog cov tshuaj Kolestiramin.
Kev Sib Tham Tshuaj
Hais txog kev sib koom ua ke ntawm cov tshuaj "Melbek" nrog rau lwm cov tshuaj, cov lus qhia rau kev siv yuav tsum tau saib xyuas tshwj xeeb, vim tias qee qhov kev sib xyaw ntawm cov nyiaj yuav tsis zoo rau cov neeg mob noj qab haus huv. Nov yog qee qhov piv txwv ntawm kev noj ntau yam tshuaj ib zaug, suav nrog Melbek, tuaj yeem cuam tshuam rau cov neeg mob:
- Anticoagulants xws li Heparin thiab Ticlopidin ua ke nrog meloxicam txo cov ntshav txhaws thiab tuaj yeem ua rau los ntshav hnyav.
- Cov tshuaj muaj lithium, thaum noj ib txhij nrog Melbek, tuaj yeem ua rau muaj kev noj ntau dhau ntawm lithium.
- Alpha-blockers thiab lwm yam tshuaj kho mob uas siv meloxicam tsis zoo.
- Diuretics noj thaum kho nrog Melbek tuaj yeem muaj zog heevua rau muaj kev pheej hmoo ntawm lub cev qhuav dej thiab kev loj hlob ntawm lub raum tsis ua haujlwm.
- Qhov ua tau zoo ntawm cov tshuaj tiv thaiv kab mob hauv lub cev thaum noj ua ke nrog cov tshuaj "Melbek" txo qis, yog li nws yog ib qho tseem ceeb rau kev ntsuas ntxiv los tiv thaiv kev xeeb tub.
- Cyclosporine ua ke nrog cov tshuaj "Melbek" tuaj yeem ua rau muaj kev nce ntxiv hauv cov nyhuv nephrotoxic tom kawg.
Muab tag nrho cov ntsiab lus saum toj no, nws yog ib qho tseem ceeb uas yuav tsum tau ua tib zoo saib xyuas qhov teeb meem ntawm kev sau tshuaj nrog rau Melbek hauv daim ntawv ntawm cov ntsiav tshuaj thiab tshuaj. Cov kws tshaj lij qhia ib txwm qhia lawv txog qhov muaj peev xwm noj ntau yam tshuaj ua ke.
Analogues
Analogues ntawm cov tshuaj "Melbek" ntawm cov tshuaj nquag (active) yog cov tshuaj hauv qab no: "Meloxicam" (xws li "Meloxicam-Prama" thiab "Meloxicam DS"), "Movalis", "Mokasin" thiab " Mesipol". Cov tshuaj no, yog tias tsim nyog, tuaj yeem hloov cov tshuaj "Melbek". Lawv muaj tib cov kev qhia, kev phiv thiab contraindications.
Analogues ntawm lawv qhov kev txiav txim yog suav tias yog lwm cov tshuaj uas tsis yog-steroidal anti-inflammatory siv tshuaj tiv thaiv kab mob, tsis muaj meloxicam. Cov no suav nrog cov tshuaj "Ketanov", "Ambene" thiab "Faspik". Lawv txoj kev siv yog tsim nyog yog tias tus neeg mob muaj intolerance rau meloxicam.
Kev tshuaj xyuas ntawm kws kho mob
Raws li cov kws tshaj lij, Melbek yog ib qho tshuaj zoo tshaj plaws los pab txo qhov mob ntawm cov kab mob xws li mob caj dab thiabarthrosis. Tsis tas li ntawd, lawv tau sau tseg tias tawm tsam keeb kwm yav dhau los ntawm lwm cov tshuaj uas tsis yog-steroidal anti-inflammatory, cov tshuaj no tsis muaj kev cuam tshuam tsis zoo rau lub plab zom mov, txawm tias siv sijhawm ntev. Qhov no yog qhov uas suav hais tias yog ib qho tseem ceeb thaum sau cov kev kho mob nrog NSAIDs.
Hais txog lub sijhawm ntawm kev noj tshuaj "Melbek" cov lus qhia, kev tshuaj xyuas ntawm cov kws tshaj lij qhia tias nws tuaj yeem noj tau ntau lub hlis. Nyob rau tib lub sijhawm, nws yog ib qho tseem ceeb uas yuav tsum tau saib xyuas los ntawm tus kws kho mob txhawm rau txhawm rau txheeb xyuas qhov tshwm sim ntawm qhov tsis xav tau ntawm lub cev rau cov tshuaj hauv lub sijhawm.
