Asherman's syndrome: ua rau, tsos mob, piav qhia, kuaj mob thiab kho

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Asherman's syndrome: ua rau, tsos mob, piav qhia, kuaj mob thiab kho
Asherman's syndrome: ua rau, tsos mob, piav qhia, kuaj mob thiab kho

Video: Asherman's syndrome: ua rau, tsos mob, piav qhia, kuaj mob thiab kho

Video: Asherman's syndrome: ua rau, tsos mob, piav qhia, kuaj mob thiab kho
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Kev tsis muaj menyuam hauv kev sib yuav yog ib qho teeb meem tseem ceeb tshaj plaws hauv zej zog. Cov kws tshawb fawb tau ua pov thawj tib lub luag haujlwm ntawm txhua tus niam txiv muaj peev xwm hauv kev daws teeb meem tsis tiav ntawm qhov teeb meem no. Txawm li cas los xij, kev coj tus me nyuam thiab kev yug me nyuam poob rau ntawm leej niam lub xub pwg nyom. Tsuas yog ib tug poj niam laus lub cev tuaj yeem ua tiav cov haujlwm no. Nyob rau hauv ob peb xyoos dhau los, muaj kev nce rau hauv cov kab mob ntawm lub cev xeeb tub, uas provoke infertility. Hauv peb lub tebchaws, txoj haujlwm tseem ceeb yog nyob los ntawm kev mob endometritis. Ib qho ntawm nws tshwm sim yog Asherman's syndrome. Puas muaj tus kab mob no cev xeeb tub?

Kev piav qhia ntawm pathology

Asherman's syndrome tau nkag siab tias yog kab mob pathological, vim tias qhov adhesions tsim hauv tsev menyuam. Lawv ua rau ib nrab lossis ua tiav ntawm nws cov kab noj hniav. Tus kab mob no tau txais nws lub npe los ntawm lub xeem gynecologist Joseph Asherman. Tus mob no tau piav qhia thawj zaug hauv 1894 los ntawm Heinrich Fritsch. Hauv cov ntaub ntawv kho mob, muaj ntau lub npe rau cov kab mob no: intrauterine synechia, traumatic atrophy thiab endometrial sclerosis.

Asherman's Syndrome
Asherman's Syndrome

Asherman's syndrome raug kuaj pom hauv cov poj niam tsis hais lawv lub hnub nyoog thiab kev sib raug zoo li cas. Intrauterine synechia yog cov ntaub so ntswg fusions uas ua rau cov phab ntsa ntawm lub cev rau ib leeg thiab ua rau lawv deformation. Raws li qhov tshwm sim ntawm cov txheej txheem pathological, ntau yam kev mob tshwm sim uas ua rau muaj kev cuam tshuam ntawm kev coj khaub ncaws. Cov tsos mob tseem ceeb ntawm tus mob yog qhia nyob rau hauv daim ntawv ntawm spontaneous rho menyuam thiab infertility.

Cov txheeb cais hais li cas txog kev kis tus kabmob no? Tom qab curettage hauv cov poj niam uas tau yug los, qhov kev pheej hmoo ntawm kev tsim tus mob yog 25%. Nrog rau lub cev xeeb tub, qhov tshwm sim ntawm adhesions nce thiab nce mus txog 30% ntawm cov neeg mob. Ib qho kev nchuav menyuam zoo ib yam tsis ua rau tus poj niam noj qab haus huv. Hauv qhov no, qhov kev pheej hmoo ntawm tus kab mob NW nyuam qhuav tshaj 7%.

Qhov laj thawj tseem ceeb

Lub tsev menyuam yog lub cev nqaij daim tawv. Sab nraud, nws yog them nrog peritoneum. Los ntawm sab hauv nws yog lined nrog endometrium, uas muaj ob txheej - haumxeeb thiab basal. Nyob ntawm theem ntawm kev coj khaub ncaws thiab nyob rau hauv kev cuam tshuam ntawm cov tshuaj hormones kev sib deev, lub endometrium tau hloov mus rau cyclic. Ze rau lub sijhawm ntawm ovulation, thaum qhov tshwm sim ntawm xeeb tub yog siab tshaj, lub tsev menyuam hauv ob sab phlu thickens. Nyob rau hauv lub ntsiab ntawm lub endometrium, muaj ib tug active tsim ntawm biologically active tshuaj. Tom qab lub qe yog fertilized, nws mus rau lub tsev menyuam, qhov chaw implantation. Kev sib cuag ntawm daim nyias nyias ntawm lub embryo nrog lub endometrium noj qab nyob zoo yog lub ntsiab mob rau kev vam meej conception. Yog hais tias fertilization tsis tshwm sim, lub functional txheejtsis lees paub, raws li pov thawj los ntawm kev coj khaub ncaws. Nrog rau qhov pib ntawm txhua lub voj voog, lub endometrium zuj zus ntxiv.

Sinechia yog qhov kev loj hlob lossis adhesions ntawm txheej sab hauv ntawm lub tsev menyuam uas ua txhaum lub physiology ntawm cov mucous membrane. Asherman's syndrome tshwm sim los ntawm kev puas tsuaj los yog raug mob rau lub basal txheej ntawm endometrium thaum lub sij hawm gynecological txheej txheem. Qhov no tej zaum yuav yog curettage tom qab rho menyuam, ntu caesarean lossis lwm yam haujlwm. Lwm qhov ua rau tus kab mob no yog endometritis. Synechiae yog tsim tawm tsam keeb kwm ntawm ntau foci ntawm o ntawm lub tsev menyuam mucosa.

Asherman Syndrome yog nws tau eco tshuaj xyuas
Asherman Syndrome yog nws tau eco tshuaj xyuas

daim duab kho mob ntawm tus mob

Cov tsos mob ntawm tus kab mob yog tshwm sim los ntawm cov txheej txheem nplaum thiab nws cov txiaj ntsig ntawm kev ua haujlwm ntawm kev ua me nyuam. Ntawm lawv, feem ntau yog cov hauv qab no:

  • kev ua haujlwm tsis zoo ntawm kev coj khaub ncaws (ntau / qis qis, mob hnyav);
  • Miscarriage;
  • txo tus naj npawb thiab lub sijhawm ntawm kev coj khaub ncaws;
  • kev tsis muaj menyuam thib ob;
  • Kuv muaj kev sib txuam ntawm cov ntshav hnyuv ntxig hauv cov uterine kab noj hniav.

Lwm cov tsos mob dab tsi uas Asherman's syndrome muaj? Tus kab mob no feem ntau nrog endometriosis ntawm qhov sib txawv ntawm qhov hnyav. Pathology yog tus cwj pwm los ntawm kev loj hlob ectopic ntawm cov txheej txheem ua haujlwm ntawm endometrium, txuas ntxiv mus rau lub tsev menyuam kab noj hniav. Qhov kev sib xyaw ua ke no cuam tshuam tsis zoo rau kev kwv yees thiab kev cia siab rau kev kho mob.

Cov tsos mob ntawm asherman syndrome
Cov tsos mob ntawm asherman syndrome

Peb qib kev hnyav

Muab kev puas tsuaj rau cov txheej txheem basal ntawm endometrium, kws kho mob haisKev faib tawm hauv qab no ntawm Asherman's Syndrome:

  • qib me me (adhesions nyob tsis tshaj 25% ntawm qhov ntim ntawm lub tsev menyuam, yooj yim puas los ntawm kev puas tsuaj);
  • theem nrab (cov koom haum yog nruj nreem kaw rau hauv lub tsev menyuam);
  • qib hnyav (adhesions muaj feem ntau ntawm cov ntaub so ntswg sclerosed, thaiv lub qhov ncauj ntawm lub tsev menyuam thiab hauv qab ntawm lub cev).

Kev txiav txim siab raws sijhawm ntawm qib ntawm cov txheej txheem pathological tso cai rau koj kho Asherman's syndrome sai.

Puas muaj kev xeeb tub?

Kev tshuaj xyuas ntawm cov kws kho mob qhia tias qhov yuav xeeb tub tus menyuam muaj tus kab mob no nyob ntawm nws qhov ua rau thiab theem. Nrog Asherman's Syndrome, qhov kev ua me nyuam muaj kev cuam tshuam loj heev. Cov phab ntsa ntawm lub tsev menyuam ua ke, lub patency ntawm cov hlab ntsha yog cuam tshuam. Yog li ntawd, lub embryo tsis tuaj yeem cog. Tsis tas li ntawd, endometrium poob nws lub peev xwm los teb rau cov kev hloov hauv cov tshuaj estrogen. Maj mam, kev xeeb tub thib ob tshwm sim, thiab nrog nws amenorrhea. Adhesions nyob rau hauv lub ncauj tsev menyuam cheeb tsam provoke lub tsub zuj zuj thiab ncua ntawm kev coj khaub ncaws txaus. Kev ua txhaum ntawm lub voj voog feem ntau qhia tau hais tias muaj qib siab ntawm pathology. Lub cev xeeb tub yog tsim nyog yog tias Asherman's syndrome raug kho raws sijhawm.

Puas IVF ua tau? Kev tshuaj xyuas ntawm cov kws kho mob tau lees paub tias hauv vitro fertilization ua rau kev txiav txim siab thaum tus kab mob nyob rau theem pib ntawm kev loj hlob. Nyob rau tib lub sijhawm, tus naj npawb ntawm adhesions tsis tuaj yeem tshaj 25% ntawm qhov ntim ntawm lub tsev menyuam, lawv yuav tsum tau nyob hauv ib cheeb tsam ntawm cov kab noj hniav.

Nws tsis tuaj yeem muab ib lo lus teb rau cov lus nug tau nthuav tawm, vim txhua tusrooj plaub yog tus kheej. Nyob ntawm qhov hnyav ntawm cov txheej txheem pathological, muaj ntau txoj hauv kev rau kev xeeb tub. Hauv qee tus poj niam, kev coj tus kheej tsis ua rau muaj teeb meem sib koom ua ke, thaum nyob hauv lwm tus nws tau nrog ntau yam teeb meem. Ib qho kev xaiv thib peb kuj tseem ua tau - kev rho menyuam tsis tu ncua, nchuav menyuam, kev xeeb tub thib ob. Tias yog vim li cas txhua tus poj niam yuav tsum tau saib xyuas nws txoj kev noj qab haus huv, ua ntu zus los ntawm kws kho mob gynecologist, thiab kho txhua yam kab mob raws sijhawm.

asherman syndrome yog cev xeeb tub
asherman syndrome yog cev xeeb tub

Tshuaj ntsuam xyuas

txhawm rau kuaj tus kab mob, cov txheej txheem siv tau siv los ua kom pom qhov uterine kab noj hniav. Yog tsis ua tsis tau, tus kws kho mob kawm txog tus neeg mob cov keeb kwm ntawm obstetric (tus naj npawb ntawm cev xeeb tub, rho menyuam, nchuav menyuam, thiab lwm yam). Ultrasound kev kuaj xyuas yog suav tias yog qhov yooj yim tshaj plaws thiab tib lub sij hawm minimally invasive txoj kev kuaj mob pelvic kabmob. Asherman's syndrome tuaj yeem lees paub los ntawm ultrasound, tab sis cov txheej txheem yuav tsum tau rov ua ob peb zaug thaum lub voj voog kom tau txais cov txiaj ntsig raug.

Tus qauv kub rau kev kuaj pom synechia yog hysteroscopy. Xws li kev tshawb fawb ntawm lub tsev menyuam kab noj hniav yuav tsum tau siv cov cuab yeej tshwj xeeb. Nws yog tswj hwm los ntawm cov kwj dej ntawm ncauj tsev menyuam, ua tsaug rau lub xeev ntawm lub cev tuaj yeem ntsuas lub sijhawm ntawm lub computer screen. Hysteroscopy tso cai rau koj los txiav txim siab qhov hnyav ntawm cov txheej txheem pathological, qhov loj thiab qhov chaw ntawm adhesions. Cov txiaj ntsig ntawm kev soj ntsuam tag nrho ntawm tus neeg mob yuav tsum tau ua ke nrog cov keeb kwm ntawm obstetric thiab kev sim kho yav dhau los. Xws litxoj hauv kev tso cai rau kwv yees qhov zoo ntawm kev kho mob.

Asherman Syndrome ntawm ultrasound
Asherman Syndrome ntawm ultrasound

txoj kev kho

kab mob me me mus rau nruab nrab teb tau zoo rau kev kho mob. Cov ntaub ntawv siab heev ntawm pathology thiab cev xeeb tub tsis sib haum. Nyob rau hauv cov ntaub ntawv no, surrogate niam los cawm. Thaum adhesions nyob rau hauv ib cheeb tsam ntawm lub uterine kab noj hniav, txoj kev IVF pab. Txawm li cas los xij, txawm tias qhov no, tsis yog txhua tus poj niam uas kuaj mob Asherman's syndrome tuaj yeem sim ua lub luag haujlwm ntawm niam.

Kev kho mob suav nrog kev tshem tawm adhesions los ntawm hysteroscopy. Kev ua haujlwm tsis tas yuav siv tshuaj loog thiab tsis muaj teeb meem. Technically, qhov no yog cov txheej txheem nyuaj heev. Kev tshem tawm ntawm synechia yog nqa tawm nrog microscissors vim qhov muaj feem yuav rov raug mob. Nyob rau lub sijhawm postoperative, kev kho tshuaj tua kab mob yog tsim los tiv thaiv kev kis kab mob. Kev kho tshuaj yuav tsum tau ntxiv nrog kev kho hormonal. Kev siv cov tshuaj estrogens thiab progestins yog qhia los txhawb kev loj hlob ntawm endometrium.

Kev kho mob Asherman's syndrome
Kev kho mob Asherman's syndrome

Huab cua

Nrog rau qib me me ntawm cov txheej txheem pathological thiab kev kho raws sijhawm, cev xeeb tub tau pom hauv 93% ntawm cov neeg mob, nrog qhov nruab nrab qib - tsuas yog hauv 78%. Kev kho mob ntawm cov poj niam uas muaj tus kab mob siab heev ua rau nws muaj peev xwm xeeb tub hauv 57% ntawm cov neeg mob. Txawm li cas los xij, kev xeeb tub ua tiav nrog Asherman's syndrome tsis lav qhov yug me nyuam yam tsis muaj kab mob. Lub hnub nyoog ntawm cov neeg mob kuj raug coj mus rau hauv tus account nyob rau hauv prognosis. Piv txwv li, 66% ntawm cov neeg mob uas muaj hnub nyoog qis dua 35 xyoo uas tau kuaj pom tus mobdegree loj muaj peev xwm ntawm conception. Rau cov poj niam tshaj 35 xyoo, daim duab no NW nyuam qhuav tshaj 24%.

cev xeeb tub nrog asherman syndrome
cev xeeb tub nrog asherman syndrome

ntsuas kev tiv thaiv

Asherman's syndrome puas tuaj yeem tiv thaiv? Curettage los yog nqus aspiration - tus kws tshaj lij ua cov txheej txheem no yuav luag tsis pom kev, tsuas yog nyob ntawm nws qhov kev paub dhau los. Cov ntaub so ntswg endometrial thaum cev xeeb tub yog mos, yog li lawv yooj yim raug mob. Raws li qhov tshwm sim, txhua qhov kev kuaj mob lossis kho kev kho mob yog ib txwm nrog kev raug mob mus rau txheej txheej basal.

Ib qho kev xaiv rau cov txheej txheem nchuav menyuam no yog kev rho menyuam tawm kho mob. Nws hais txog kev txhawb nqa kev ua haujlwm los ntawm kev siv tshuaj. Txawm li cas los xij, qhov ua tau zoo ntawm txoj kev no tsuas yog 80%. Hauv 10% ntawm cov neeg mob, tom qab kev rho menyuam tawm kho mob, kev kis kab mob ntawm daim nyias nyias yog pom, uas yuav tsum tau kho. Yog li, nws muaj peev xwm tiv thaiv Asherman's syndrome yog tias kev rho menyuam tawm kho mob raug xaiv rau kev kho mob. Ntawm qhov tod tes, cov txheej txheem no tsis muab 100% lav ntawm qhov txiaj ntsig zoo.

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