Systemic inflammatory response syndrome: ICD

Cov txheej txheem:

Systemic inflammatory response syndrome: ICD
Systemic inflammatory response syndrome: ICD

Video: Systemic inflammatory response syndrome: ICD

Video: Systemic inflammatory response syndrome: ICD
Video: Qhia txog tus tib neeg pob ntseg nrov2 thiab mob ntsws los yog hnoos mob ib ce yuav ua li cad 2024, Kaum ib hlis
Anonim

Kuj hu ua SIRS, Cov Kab Mob Kab Mob Kab Mob Sib Kis (SIRS) yog kab mob pathological uas ua rau muaj kev pheej hmoo ntau ntxiv rau tus neeg mob. SIRS muaj peev xwm tiv thaiv keeb kwm yav dhau los ntawm kev phais mob, uas tam sim no nthuav dav heev, tshwj xeeb, thaum nws los txog rau cov kab mob malignant. Tsis yog kev phais, tus neeg mob kho tsis tau, tab sis kev cuam tshuam tuaj yeem ua rau SIRS.

systemic inflammatory kab mob syndrome
systemic inflammatory kab mob syndrome

Txoj kev ntawm qhov teeb meem

Vim tias cov kab mob inflammatory teb nyob rau hauv kev phais tshwm sim ntau zaus nyob rau hauv cov neeg mob uas raug kho tawm tsam keeb kwm ntawm kev qaug zog, kev mob, qhov tshwm sim ntawm kev mob hnyav yog txiav txim siab los ntawm cov kev mob tshwm sim ntawm lwm txoj kev kho mob siv nyob rau hauv ib rooj plaub tshwj xeeb.. Txawm hais tias qhov kev raug mob tshwm sim los ntawm kev ua haujlwm nyob rau qhov twg, lub sijhawm rov ua haujlwm thaum ntxovua rau muaj kev pheej hmoo ntawm kev puas tsuaj thib ob.

Raws li paub los ntawm pathological anatomy, qhov systemic inflammatory teb syndrome kuj yog vim qhov tseeb tias ib qho kev ua haujlwm provokes o hauv daim ntawv mob. Qhov hnyav ntawm cov tshuaj tiv thaiv zoo li no yog txiav txim siab los ntawm qhov hnyav ntawm qhov tshwm sim, ntau qhov kev pabcuam phenomena. Qhov tsis zoo ntawm keeb kwm yav dhau ntawm kev ua haujlwm, qhov nyuaj dua nws yuav ua rau VSV.

Yuav ua li cas thiab ua li cas?

Systemic inflammatory response syndrome yog ib yam mob uas qhia tau tias nws tus kheej tachypnea, kub taub hau, lub plawv dhia tsis zoo. Kev ntsuam xyuas qhia tias leukocytosis. Nyob rau hauv ntau txoj kev, cov lus teb ntawm lub cev yog vim lub peculiarity ntawm kev ua ntawm cytokines. Pro-inflammatory cellular qauv uas piav qhia SIRS thiab sepsis tsim lub npe hu ua thib ob nthwv dej ntawm cov neeg kho kom haum xeeb, vim tias cov kab mob hauv lub cev tsis zoo. Qhov no cuam tshuam nrog kev phom sij ntawm hypercytokinemia, ib qho mob uas ua rau muaj kev puas tsuaj rau cov ntaub so ntswg thiab cov kabmob ntawm tus kheej lub cev.

Qhov teeb meem ntawm kev txiav txim siab thiab kwv yees qhov tshwm sim ntawm qhov tshwm sim ntawm cov kab mob inflammatory teb rau lub cev, hauv ICD-10 coded R65, thaum tsis muaj ib txoj hauv kev tsim nyog rau kev ntsuam xyuas thawj lub xeev ntawm tus neeg mob. Muaj ntau ntau txoj kev xaiv thiab gradations uas tso cai rau koj los txiav txim seb tus neeg mob qhov kev noj qab haus huv phem npaum li cas, tab sis tsis muaj leej twg cuam tshuam txog kev pheej hmoo ntawm SIRS. Nws raug coj mus rau hauv tus account tias thawj 24 teev tom qab kev cuam tshuam, SIRS tshwm sim yam tsis tau poob, tab sis qhov kev siv ntawm tus mob sib txawv - qhov no yog txiav txim siab los ntawm cov txheej txheem nyuaj. Yog tias qhov tshwm sim hnyav, ntev,ua rau kom muaj qhov teeb meem, mob ntsws.

systemic inflammatory syndrome yog
systemic inflammatory syndrome yog

About cov ntsiab lus thiab kev xav

Systemic inflammatory response syndrome, coded li R65 nyob rau hauv ICD-10, tau txiav txim siab nyob rau hauv 1991 ntawm lub rooj sib tham coj ua ke cov kws txawj nyob rau hauv mob hnyav thiab pulmonology. Nws tau txiav txim siab kom lees paub SIRS yog qhov tseem ceeb, uas cuam tshuam txog cov txheej txheem inflammatory ntawm tus kab mob sib kis. Xws li cov tshuaj tiv thaiv kab mob cuam tshuam nrog kev faib tawm ntawm cytokines, thiab nws tsis tuaj yeem coj cov txheej txheem no los ntawm kev tswj hwm ntawm lub cev. Inflammatory mediators yog tsim nyob rau hauv lub hom phiaj tseem ceeb ntawm kev kis tus kab mob, los ntawm qhov chaw uas lawv tsiv mus nyob ib ncig ntawm cov ntaub so ntswg, yog li nkag mus rau hauv lub circulatory system. Cov txheej txheem pib nrog kev koom tes ntawm macrophages, activators. Lwm cov ntaub so ntswg ntawm lub cev, tej thaj chaw deb ntawm lub hom phiaj tseem ceeb, dhau los ua thaj chaw ntawm kev tsim cov tshuaj zoo sib xws.

Tus neeg sib kho mob feem ntau, raws li kev kho mob ntawm cov kab mob inflammatory teb, yog histamine. Cov teebmeem zoo sib xws muaj cov yam ntxwv uas ua rau cov platelets, nrog rau cov kev cuam tshuam nrog cov txheej txheem necrotic. Tej zaum qhov kev koom tes ntawm cov nplaum molecular qauv ntawm cov cell, qhov chaw ntawm cov khoom ntxiv, nitric oxides. SIRS tej zaum yuav yog vim muaj kev ua ntawm cov khoom lom ntawm oxygen transformation thiab lipid peroxidation.

Pathogenesis

Sau los ntawm R65 code hauv ICD-10, cov kab mob inflammatory teb tshwm sim tshwm sim thaum tus neeg tiv thaiv tsis tuaj yeem tswj thiab tua.active systemic tshaj tawm ntawm yam pib inflammatory txheej txheem. Muaj kev nce hauv cov ntsiab lus ntawm cov neeg nruab nrab hauv cov hlab ntsha, uas ua rau tsis ua haujlwm ntawm cov kua dej microcirculation. Lub capillary endothelium ua ntau permeable, cov tshuaj lom ntawm lub txaj nkag mus los ntawm cov kab nrib pleb ntawm cov ntaub so ntswg mus rau cov hlwb nyob ib puag ncig cov hlab ntsha. Nyob rau tib lub sijhawm, foci tshwm sim nyob deb ntawm qhov chaw thawj zaug, kev ua haujlwm tsis txaus ntawm kev ua haujlwm ntawm ntau yam kev tsim sab hauv tau pom. Raws li qhov tshwm sim ntawm cov txheej txheem no - DIC syndrome, tuag tes tuag taw ntawm kev tiv thaiv kab mob, kev ua haujlwm tsis txaus ntawm ntau lub cev.

Raws li pom los ntawm ntau cov kev tshawb fawb txog qhov tshwm sim ntawm cov kab mob inflammatory teb nyob rau hauv obstetrics, phais, oncology, cov lus teb zoo li no tshwm sim ob qho tib si thaum tus kab mob nkag mus rau hauv lub cev, thiab teb rau qee yam kev ntxhov siab. SIRS tuaj yeem tshwm sim los ntawm somatic pathology lossis ib tus neeg raug mob. Qee zaum, lub hauv paus ua rau muaj kev tsis haum rau cov tshuaj, ischemia ntawm qee qhov ntawm lub cev. Rau qee qhov, SIRS yog cov lus teb thoob ntiaj teb ntawm tib neeg lub cev rau cov txheej txheem tsis zoo tshwm sim hauv nws.

systemic inflammatory obstetric syndrome
systemic inflammatory obstetric syndrome

Subtleties ntawm qhov teeb meem

Kawm txog cov kab mob inflammatory teb nyob rau hauv obstetrics, phais, thiab lwm yam ceg ntawm cov tshuaj, cov kws tshawb fawb tau saib xyuas tshwj xeeb rau cov kev cai rau kev txiav txim siab xws li ib tug mob, nrog rau cov intricacies ntawm kev siv ntau yam terminologies. Tshwj xeeb, nws ua rau kev txiav txim siab los tham txogsepsis, yog hais tias tus kab mob tsom mus rau qhov ua rau o nyob rau hauv ib tug systemic daim ntawv. Tsis tas li ntawd, sepsis raug soj ntsuam yog tias kev ua haujlwm ntawm qee qhov ntawm lub cev raug cuam tshuam. Sepsis tuaj yeem kuaj tau tsuas yog nrog kev xaiv ntawm ob qho kev qhia: SIRS, kab mob ntawm lub cev.

Yog tias pom tshwm sim uas tso cai rau ib tus neeg xav tias tsis ua haujlwm ntawm lub cev thiab lub cev, uas yog, cov tshuaj tiv thaiv tau nthuav dav dua li qhov tseem ceeb, qhov sib txawv loj ntawm cov kab mob sepsis raug kuaj pom. Thaum xaiv ib qho kev kho mob, nws yog ib qho tseem ceeb kom nco ntsoov qhov muaj peev xwm ntawm transient bacteremia, uas tsis ua rau muaj kev nthuav dav ntawm cov txheej txheem sib kis. Yog tias qhov no tau dhau los ua qhov ua rau SIRS, lub cev tsis ua haujlwm, nws yog ib qho tsim nyog yuav tau xaiv cov kev kho mob uas tau qhia rau sepsis.

Qeb thiab qhov hnyav

Raws li cov txheej txheem kuaj mob rau cov kab mob inflammatory teb, nws yog ib txwm ua kom paub qhov txawv ntawm plaub hom mob. Cov cim tseem ceeb uas tso cai rau koj tham txog SIRS:

  • kub siab tshaj 38 degrees lossis kub qis dua 36 degrees;
  • lub plawv dhia ntau dua 90 tus neeg ntaus ib feeb;
  • ua pa ntau dua 20 ua ib feeb;
  • nrog lub tshuab ua pa RCO2 tsawg dua 32 units;
  • leukocytes hauv kev tshuaj ntsuam tau txhais tias yog 1210^9 units;
  • leucopia 410^9 units;
  • tshiab leukocyte cov ntaub ntawv ntau dua 10% ntawm tag nrho.

Yuav kuaj tau SIRS, tus neeg mob yuav tsum muaj ob lossis ntau dua ntawm cov cim no.

Hais txog kev xaiv

Yog tus neeg mob muaj ob lossis ntau qhov cim ntawm qhov tshwm sim saum toj nosystemic inflammatory teb syndrome, thiab cov kev tshawb fawb qhia tau hais tias lub hom phiaj ntawm kev kis kab mob, kev soj ntsuam ntawm cov ntshav kuaj muab ib lub tswv yim ntawm cov kab mob uas ua rau tus mob, sepsis yog kuaj.

systemic inflammatory teb syndrome
systemic inflammatory teb syndrome

Nyob rau hauv cov ntaub ntawv ntawm insufficiency loj hlob raws li ib tug ntau yam ntawm lub cev scenario, nyob rau hauv cov ntaub ntawv ntawm mob tsis ua hauj lwm nyob rau hauv tus neeg mob lub siab lub ntsws, lactic acidosis, oliguria, pathological heev txo cov ntshav siab nyob rau hauv cov hlab ntsha, ib tug mob sepsis yog kuaj tau.. Tus mob yog tswj los ntawm kev kho mob hnyav.

Septic shock yog kuaj pom yog tias sepsis tsim nyob rau hauv daim ntawv hnyav, ntshav siab qis tau pom nyob rau hauv qhov sib txawv ruaj khov, perfusion tsis ua haujlwm ruaj khov thiab tsis tuaj yeem tswj tau los ntawm cov txheej txheem classical. Hauv SIRS, hypotension yog suav tias yog ib qho mob uas lub siab tsawg dua 90 units lossis tsawg dua 40 units ntawm tus neeg mob, thaum tsis muaj lwm yam uas tuaj yeem ua rau txo qis hauv qhov ntsuas. Nws raug coj mus rau hauv tus account tias kev noj tshuaj ntawm qee yam tshuaj tuaj yeem ua ke los ntawm kev tshwm sim qhia txog kev ua haujlwm ntawm lub cev, teeb meem perfusion, thaum lub siab tswj kom txaus.

Nws puas tuaj yeem mob ntxiv?

Cov chav kawm hnyav tshaj plaws ntawm cov kab mob inflammatory teb tau pom yog tias tus neeg mob tau ua haujlwm tsis zoo ntawm ib khub lossis ntau lub cev uas tsim nyog los tswj kev muaj sia nyob. Tus mob no yog hu ua ntau yam kabmob tsis ua haujlwm syndrome. Qhov no ua tau yog tias SIRS hnyav heev, thaum noj tshuajthiab cov txheej txheem ntsuas tsis tso cai rau tswj thiab ua kom ruaj khov homeostasis, tshwj tsis yog cov txheej txheem thiab cov txheej txheem ntawm kev kho mob hnyav.

Kev Tsim Kho Tswv Yim

Tam sim no, lub tswv yim ob theem tau paub hauv cov tshuaj los piav txog kev txhim kho ntawm SIRS. Lub cytokine cascade ua lub hauv paus ntawm cov txheej txheem pathological. Nyob rau tib lub sijhawm, cytokines uas pib cov txheej txheem inflammatory yog qhib, thiab nrog lawv cov neeg kho kom haum xeeb uas inhibit qhov kev ua ntawm cov txheej txheem inflammatory. Muaj ntau txoj hauv kev, yuav ua li cas cov kab mob inflammatory teb yuav tshwm sim thiab txhim kho yog txiav txim siab los ntawm qhov sib npaug ntawm ob yam ntawm cov txheej txheem.

SIRS tab tom nce qib mus. Thawj hauv science yog hu ua induction. Qhov no yog lub sijhawm thaum lub sijhawm ua kom pom tseeb ntawm qhov mob hauv zos, vim muaj cov tshuaj tiv thaiv ib txwm muaj rau kev cuam tshuam ntawm qee qhov kev ua phem. Qhov thib ob theem yog ib tug cascade, nyob rau hauv uas muaj ntau inflammatory mediators yog generated nyob rau hauv lub cev uas yuav nkag mus rau hauv lub circulatory system. Nyob rau theem thib peb, qhov kev ua phem thib ob tshwm sim, qhia ntawm tus kheej lub hlwb. Qhov no piav qhia txog cov txheej txheem ntawm cov kab mob inflammatory teb, qhov tshwm sim ntxov ntawm kev ua haujlwm ntawm lub cev tsis txaus.

theem plaub yog immunological paralysis. Nyob rau theem ntawm txoj kev loj hlob no, muaj kev nyuaj siab heev ntawm kev tiv thaiv kab mob, kev ua haujlwm ntawm lub cev muaj kev cuam tshuam ntau heev. Qhov thib tsib thiab zaum kawg yog lub davhlau ya nyob twg.

inflammatory teb syndrome pathophysiology
inflammatory teb syndrome pathophysiology

Yuav pab tau dab tsi?

Yog koj xav tau kev pabThaum lub sij hawm lub sij hawm ntawm lub systemic inflammatory teb syndrome, qhov kev pom zoo ntawm kev kho mob yog los saib xyuas tus neeg mob tus mob, tsis tu ncua noj cov ntsiab lus ntawm kev ua hauj lwm ntawm lub cev tseem ceeb, thiab kuj siv tshuaj. Yog tias tsim nyog, tus neeg mob txuas nrog cov cuab yeej tshwj xeeb. Tsis ntev los no, cov tshuaj tsim tshwj xeeb rau kev kho mob ntawm SIRS hauv nws cov kev tshwm sim ntau yam zoo li kev cog lus tshwj xeeb.

Cov tshuaj zoo rau SIRS raws li diphosphopyridine nucleotide, kuj suav nrog inosine. Qee cov qauv ntawm kev tso tawm muaj digoxin, lisinopril. Cov tshuaj sib xyaw ua ke, xaiv los ntawm kev txiav txim siab ntawm tus kws kho mob tuaj koom, inhibit SIRS, tsis hais dab tsi ua rau cov txheej txheem pathological. Cov neeg tsim khoom paub tseeb tias cov txiaj ntsig tau hais tuaj yeem ua tiav hauv lub sijhawm luv tshaj plaws.

Kuv puas xav tau kev phais?

Kev phais ntxiv tuaj yeem raug sau rau SIRS. Nws qhov tsim nyog yog txiav txim siab los ntawm qhov mob hnyav, nws cov chav kawm thiab kev kwv yees kev loj hlob. Raws li txoj cai, nws muaj peev xwm ua tau ib qho kev cuam tshuam ntawm lub cev, thaum lub sij hawm qhov chaw ntawm suppuration yog drained.

inflammatory teb cov lus qhia kho mob
inflammatory teb cov lus qhia kho mob

Tshuaj nyob rau hauv nthuav dav

Kev txheeb xyuas cov khoom siv tshuaj ntawm diphosphopyridine nucleotide ua ke nrog inosine tau muab sijhawm rau cov kws kho mob tshiab. Xws li cov tshuaj, raws li kev xyaum qhia, muaj feem xyuam rau kev ua hauj lwm ntawm cardiologists thiab nephrologists, kws phais thiab pulmonologists. Kev npaj nrog cov tshuaj no yog siv los ntawm anesthesiologists, gynecologists, endocrinologists. Tam sim noCov tshuaj yog siv rau hauv kev phais mob ntawm lub plawv thiab cov hlab ntsha, yog tias tsim nyog, muab kev pab rau tus neeg mob hauv chav saib xyuas mob hnyav.

Qhov kev siv dav dav no cuam tshuam nrog cov tsos mob dav dav ntawm sepsis, qhov tshwm sim ntawm kev kub hnyiab, tshwm sim ntawm cov ntshav qab zib tshwm sim hauv cov neeg xiam oob khab, poob siab rau keeb kwm ntawm kev raug mob, SDS, cov txheej txheem necrotic hauv pancreas thiab ntau lwm yam mob hnyav tshwm sim. Cov tsos mob complex muaj nyob rau hauv SIRS, thiab zoo nres los ntawm diphosphopyridine nucleotide ua ke nrog inosine, muaj xws li qaug zog, mob, thiab pw tsaug zog. Cov tshuaj no txo cov mob ntawm tus neeg mob uas muaj mob taub hau thiab kiv taub hau, cov tsos mob ntawm encephalopathy tshwm sim, daim tawv nqaij tig daj ntseg los yog daj, lub atherosclerosis thiab zaus ntawm lub plawv contractions cuam tshuam, thiab ntshav tsis txaus.

Cov txheej txheem kuaj mob ntshav qab zib
Cov txheej txheem kuaj mob ntshav qab zib

Kev cuam tshuam ntawm qhov teeb meem

Raws li pom los ntawm kev tshawb fawb txheeb cais, SIRS tam sim no yog ib qho ntawm cov kev xaiv ntau tshaj plaws rau kev loj hlob ntawm hypoxia, muaj zog ua kom puas hlwb hauv cov ntaub so ntswg. Tsis tas li ntawd, xws li ib tug syndrome nrog ib tug high degree ntawm qhov tshwm sim tshwm sim tawm tsam keeb kwm yav dhau ntawm intoxication. Pathogenesis, etiology ntawm cov xwm txheej ua rau SIRS txawv heev.

Txawm li cas los xij, yeej muaj SIRS. Cov tshuaj tiv thaiv dhau los ua ib qho ntawm sepsis, ib qho mob pathological tshwm sim los ntawm kev raug mob lossis kub hnyiab. Nws tsis tuaj yeem zam tau yog tias tus neeg tau muaj TBI lossis phais. Raws li kev soj ntsuam tau pom, SIRSkuaj pom nyob rau hauv cov neeg mob uas muaj kab mob ntawm bronchi, ntsws, uremia, oncology, phais pathological mob. Nws yog tsis yooj yim sua kom tshem tawm SIRS yog hais tias ib tug inflammatory txheej txheem los yog necrotic tsim nyob rau hauv lub txiav txiav, plab kab noj hniav.

Raws li qhia los ntawm cov kev tshawb fawb tshwj xeeb, SIRS kuj tau pom nyob rau hauv ntau cov kab mob uas muaj txiaj ntsig zoo dua. Raws li txoj cai, nrog lawv, tus mob no tsis hem tus neeg mob lub neej, tab sis txo qis nws qhov zoo. Peb tab tom tham txog lub plawv nres, ischemia, kub siab, preeclampsia, kub hnyiab, osteoarthritis.

Pom zoo: