Glomerulonephritis hauv cov menyuam yaus yog ib qho mob ntawm cov kab mob sib kis uas cuam tshuam rau lub raum glomeruli, lossis nephrons, uas yog lub tsev tseem ceeb ntawm lub cev. Manifested los ntawm hematuria, proteinuria, o ntawm lub ntsej muag thiab teeb meem nrog zis. Tus kab mob tuaj yeem tshwm sim hauv daim ntawv mob hnyav lossis mob ntev. Xav txog dab tsi yog glomerulonephritis, cov tsos mob thiab kev kho mob hauv cov menyuam yaus.
Dab tsi yog glomerulonephritis hauv menyuam yaus?
Lub raum yog ib qho khoom ua ke uas muaj lub luag haujlwm tshem tawm cov khib nyiab, dej thiab electrolytes (potassium, sodium, calcium) los ntawm lub cev hauv cov zis. Lawv qhov mob hnyav lossis mob ntev ua rau muaj kev puas tsuaj ib ntus lossis mus tas li hauv kev ua haujlwm.
Qhov txuas tseem ceeb ntawm ob lub raum lub luag haujlwm rau kev ua haujlwm pom (tu) yog glomeruli (glomeruli ntawm ob lub raum). Lub ntsiab tseem ceeb ntawm cov glomeruli yog lawv daim nyias nyias, uas yog tsim los lim cov ntshav thiab tshem tawm cov khoom sib xyaw thiabdej hauv cov zis. Nyob rau hauv cov ntaub ntawv ntawm lub raum ua haujlwm ib txwm, lub lim membrane khaws tag nrho cov khoom xyaw tsim nyog hauv tib neeg cov ntshav, suav nrog cov protein, yog li cov protein ib txwm tsis raug soj ntsuam hauv kev kuaj zis.
Glomerulonephritis yog ib pawg kab mob uas ua raws li kev puas tsuaj rau glomerular filtration membrane, uas pib ua kom cov protein thiab cov qe ntshav liab mus rau hauv cov zis. Qhov no yuav yog vim muaj kab mob los yog kab mob. Tus kab mob kuj tseem muaj keeb kwm caj ces. Nws tuaj yeem tshwm sim hauv qhov mob hnyav, luv luv, feem ntau cuam tshuam nrog kev kis kab mob (piv txwv li, tom qab mob caj pas), lossis nyob rau hauv qhov mob, qee zaum ua rau lub raum puas tsuaj mus tas li.
Hom glomerulonephritis
Cov kab mob hauv qab no yog qhov txawv:
- hematuric - muaj hematuria thiab arterial hypertension;
- nephrotic - hydrothorax tshwm, hais tawm edema;
- hypertensive - ntshav siab;
- combined - sib txuas tag nrho cov tsos mob ntawm cov ntaub ntawv saum toj no;
- hidden (latent) - tsis muaj tsos mob.
Daim ntawv latent ntawm tus kab mob yog qhov txaus ntshai dua, vim tias nws cov tsos mob tuaj yeem kav ntev li 10-15 xyoo. Nws qhov kev kuaj pom yog ua tau los ntawm kev sib tsoo hauv kev soj ntsuam cov zis, lossis nrog kev txhim kho ntawm cov teeb meem. Muaj kev pom zoo nrog kev kho mob raws sijhawm. Hematuric glomerulonephritis hauv cov menyuam yaus, nrog rau hom kab mob nephrotic, muaj qhov tshwm sim tsis zoo. Nrog rau daim ntawv mob hnyav thiab kev kuaj mob ntxov thiab kev kho kom txaus, ua tiavrov qab los. Yog tias tsis muaj kev ntsuas kho mob li ntawm rau lub hlis lossis siv cov kev kho mob tsis raug, cov txheej txheem yuav mob ntev. Cov qauv kev kho mob ntawm tus mob glomerulonephritis nyob rau hauv cov menyuam yaus txawv ntawm cov kev kho mob siv nyob rau hauv daim ntawv ntawm tus kab mob. Nyob rau hauv tas li ntawd, txoj kev kho yuav ntev dua, complex thiab kim, thiab cov prognosis yuav tsis xis nyob.
Tus mob glomerulonephritis yog dab tsi thiab nws yog vim li cas?
Cov menyuam yaus feem ntau yuav raug mob glomerulonephritis dua li cov laus. Pathology tshwm sim ntau zaus hauv cov tub hluas dua li cov ntxhais. Qhov tshwm sim siab tshaj plaws tshwm sim thaum muaj hnub nyoog kawm ntawv (7-10 xyoo), cov menyuam yaus hnub nyoog qis dua 3 xyoos tsis tshua muaj mob. Mob glomerulonephritis suav txog li 10-15% ntawm txhua hom glomerulonephritis thiab tshwm sim hauv 2-5 tus neeg mob rau 100,000 tus menyuam hauv ib xyoos.
Tus mob glomerulonephritis feem ntau yog ua ntej los ntawm kev ua pa sab saud lossis kab mob ntawm daim tawv nqaij. Lub luag haujlwm tseem ceeb hauv kev tsim cov kab mob hnyav yog ua si los ntawm kev tiv thaiv kab mob (lub cev cov lus teb rau kev kis kab mob), uas ua rau cov glomeruli puas, uas ua rau pom cov protein thiab cov qe ntshav liab hauv cov zis.
Yuav ua li cas mob glomerulonephritis manifests nws tus kheej
Feem ntau, tus kab mob pib nrog cov tsos mob ntawm edema nyob ntawm lub ntsej muag (qhov muag o tom qab pw tsaug zog) lossis ib ncig ntawm pob taws ntawm ob txhais ceg, nrog rau hematuria. Cov zis tuaj yeem yog xim liab lossis xim av tsaus. Cov menyuam yaus feem ntau tsis muaj qhov kub thiab txias thaum lub sijhawm no. Cov kev hloov no tshwm sim 5-21 hnub tom qab mob caj pas thiab ua pa sab sauv.los yog 3-4 lub lis piam tom qab dermatitis. Edema tshwm sim hauv yuav luag txhua tus neeg mob. Nws tuaj yeem nyob mus txog ob lub lis piam tom qab pib tus kab mob thiab cuam tshuam nrog dej thiab sodium tuav hauv lub cev. Tus me nyuam yws yws ntawm qhov mob plab, ntuav, mob taub hau, apathy tshwm sim, qab los noj mov tsis zoo. Cov kev hloov no feem ntau nrog kev kub siab.
Nyob tsis tshua muaj neeg, nrog rau cov ntshav siab ntau, qhov hu ua hypertensive ntsoog nrog convulsions tuaj yeem tshwm sim. Qee zaum, muaj qhov txo qis hauv cov zis, mus txog qhov tshwm sim ntawm lub raum tsis ua haujlwm, suav nrog anuria. Yog tias cov xim ntawm cov zis hloov pauv, qhov o ntawm lub ntsej muag lossis pob taws tshwm sim, sab laj nrog kws kho mob tam sim ntawd txhawm rau kuaj xyuas thiab kho tus mob glomerulonephritis hauv cov menyuam yaus.
Tus kws kho mob ua li cas thiaj kuaj tau?
Lab tests:
Qhov kev kuaj thawj zaug yog kuaj zis, uas yuav tsum tau ua ib txwm ua thaum xav tias mob glomerulonephritis. Cov yam ntxwv sib txawv hauv txoj kev tshawb no:
- microscopic los ntshav (uas yog, muaj cov qe ntshav liab nyob rau hauv cov zis ntau npaum li cas tsis pom ntawm qhov muag liab qab, tab sis pom tau los ntawm kev tshuaj xyuas microscopic), uas yog cov tsos mob tas li ntawm tus kab mob;
- proteinuria - tus nqi ntawm cov protein poob hauv cov zis thaum nruab hnub, feem ntau tsis tshaj 3 g;
- muaj cov qe ntshav dawb (tsis tshua muaj).
kuaj ntshav qhia:
- txo qis hauv cov khoom ntxiv C3 thiab hemolyticntxiv kev ua si (CH50);
- nce hauv ASO titer (antistreptolysin O) siab dua 200 IU;
- mob hnyav anemia;
- nyob rau hauv ib nrab ntawm cov neeg mob, qhov nce hauv qhov concentration ntawm immunoglobulin IgG.
Thaum saib cov kev sib txawv saum toj no hauv kev tshawb fawb hauv cov menyuam yaus uas muaj glomerulonephritis, kev kho mob thiab kev kuaj mob tau ua raws li kev saib xyuas ntawm tus kws kho mob nephrologist.
Yog tias koj xav tias mob glomerulonephritis hauv tsev kho mob, koj yuav tsum ntsuas ntshav siab, thiab rov ua qhov kev soj ntsuam ntawm nws dhia 3-4 zaug hauv ib hnub. Ultrasound scanning ntawm ob lub raum feem ntau tsis qhia cov yam ntxwv hloov. Hauv feem ntau ntawm cov xwm txheej, tsis tas yuav tsum muaj lub raum biopsy. Kev kuaj ntshav biopsy tsuas yog ua nrog lub sijhawm ntev ntawm cov zis me me ntawm lub cev kom sib txawv ntawm lub raum tsis ua haujlwm lossis ua rau mob glomerulonephritis sai.
Kev kho mob glomerulonephritis hauv menyuam yaus
Kev kho mob ntawm tus kab mob hnyav yog cov tsos mob thiab feem ntau ua hauv tsev kho mob. Nws yog ib qho tsim nyog los muab kev thaj yeeb nyab xeeb thiab so rau tus neeg mob. Kev kho mob ntawm glomerulonephritis hauv cov menyuam yaus kuj muaj kev tshem tawm ntawm arterial hypertension thiab diuretic hypertension.
Tshuaj tua kab mob yog qhia rau kev txhim kho mob glomerulonephritis nrog pharyngitis, tonsillitis, daim tawv nqaij mob, tshwj xeeb tshaj yog nrog cov txiaj ntsig zoo ntawm cov kab mob hauv caj pas lossis nrog cov tshuaj tiv thaiv kab mob siab hauv cov ntshav.
Kev kho mob tom qab mob streptococcal glomerulonephritis hauv cov menyuam yaus yog ua nrog tshuaj tua kab mob los ntawm pab pawgpenicillins, cephalosporins rau 10 hnub.
Yog tias muaj proteinuria siab, tus menyuam tau txais 20% tshuaj ntawm tib neeg albumin. Thaum tus me nyuam tsis tso zis ntev thiab qhov o tuaj, cov kws kho mob yuav xav txog kev kho lub raum (dialysis). Tom qab tso tawm hauv tsev kho mob, yuav tsum tau kuaj zis ib ntus (ib zaug txhua ob lub lis piam). Nyob rau hauv cov ntaub ntawv ntawm kev soj ntsuam mus sij hawm ntev ntawm cov kev hloov nyob rau hauv cov zis (hematuria, proteinuria), nws yuav tsum tau hu rau ib tug pediatric nephrologist.
Nws puas tuaj yeem rov qab tau zoo?
Tus mob glomerulonephritis yog ib yam kab mob loj, tab sis nrog kev pom zoo. Feem ntau cov tsos mob yuav ploj mus tsis pub dhau ob peb lub lis piam lossis hli. Nrog rau kev kho mob zoo ntawm mob glomerulonephritis hauv cov menyuam yaus, kev rov qab los ntawm tus kab mob yog tsawg. Txawm li cas los xij, koj yuav tsum paub txog kev kuaj zis ib ntus (ib zaug hauv ib lub hlis twg) thiab ntsuas ntshav siab. Tsawg kawg yog ib xyoos tom qab mob glomerulonephritis, tus me nyuam yuav tsum nyob rau hauv kev saib xyuas ntawm tus kws kho mob nephrologist.
Dab tsi yog mob glomerulonephritis thiab nws yog vim li cas
Qhov ua rau muaj cov kab mob glomerulonephritis ntev yog ua txhaum ntawm tus menyuam lub cev tiv thaiv kab mob. Raws li qhov tshwm sim ntawm lub cev cov tshuaj tiv thaiv kab mob, cov tshuaj tiv thaiv yog tsim tawm tsam glomerular antigens thiab cov tshuaj tiv thaiv kab mob hauv cov hlab ntsha los yog ob lub raum thiab ua rau cov membrane puas. Cov kab mob glomerulonephritis ntev yuav yog thawj (tsuas yog ob lub raum) lossis lwm qhov chaw ntawm qhov txhab (xws li, kab mob siab, kab mob, mob qog noj ntshav). Thaum yauCov kab mob glomerulonephritis ntev heev. Hauv cov menyuam yaus, cov tsos mob, ua rau, kev kho mob ntawm tus kab mob yog ntau haiv neeg thiab nyob ntawm seb hom glomerular o. Cov neeg mob feem ntau muaj proteinuria, hematuria, thiab edema. Qee qhov xwm txheej, qhov rov tshwm sim ntawm tus kab mob tshwm sim, piv txwv li, tshwm sim los ntawm tus kab mob ua pa sab saud.
Kev kuaj mob ntawm qee yam ntawm glomerulonephritis tsuas yog nyob ntawm lub raum biopsy xwb. Qhov no tseem ceeb heev vim tias muaj ntau hom kab mob tuaj yeem tshwm sim nrog cov tsos mob zoo sib xws, thiab kev kho mob tshwj xeeb yog nyob ntawm nws daim ntawv.
Tus mob glomerulonephritis ntev li cas tshwm sim nws tus kheej?
Glomerulonephritis feem ntau tshwm sim los ntawm proteinuria thiab edema, qee zaum nrog hematuria. Qhov pib ntawm tus kab mob tuaj yeem yog qhov tsis txaus ntseeg yam tsis muaj cov tsos mob tshwm sim. Tus menyuam tuaj yeem qaug zog, yws yws ntawm qhov tsis qab los noj mov. Maj mam, o tuaj yeem tshwm sim ntawm lub ntsej muag ze ntawm lub qhov muag, tshwj xeeb tshaj yog tom qab pw tsaug zog, ntawm ob txhais ceg nyob ib ncig ntawm pob taws, los yog o pom thoob plaws hauv tus menyuam lub cev. Tus menyuam nce qhov hnyav sai, txawm tias tsis qab los noj mov. o tuaj yeem kuaj pom los ntawm nias ntawm tus menyuam ko taw ncig pob taws. Thaum nws o, "dimple" tseem nyob tom qab siab - me me nrog me ntsis o thiab tob nrog qhov o zoo heev.
Hauv cov menyuam yaus hnub nyoog 1 txog 12 xyoos, hom kab mob feem ntau yog hu ua idiopathic nephrotic syndrome. Nws tshwm sim nrog ntau zaus ntawm 2-7 kis ntawm 100,000 tus menyuam hauv ib xyoos. Hauv cov menyuam yaus, cov tub hluas muaj 2-3 zaug yuav kis tus kabmob ntau dua li cov ntxhais. Feem ntau cov xwm txheej tau sau npe ua ntej hnub nyoog rau rau xyoo. Ib qho tshwj xeeb ntawm idiopathic nephrotic syndrome yog nws rov tshwm sim. Yog tias edema tshwm sim (piv txwv li, nyuaj rau kev hnav khau, hnyav nce sai), nws yog ib qho tseem ceeb mus ntsib kws kho mob kom paub tseeb tias tus mob glomerulonephritis nyob rau hauv cov me nyuam, tus kws kho mob yuav tsum tau muab tshuaj kho raws li hom kab mob.
Diagnosis
Kev tshawb fawb txog kev tso zis - urinalysis. Yog tias pom muaj protein ntau hauv cov zis, nws yog ib qho tsim nyog yuav tsum rov ntsuas dua tom qab 1-2 hnub los ntsuas seb puas muaj protein ntau ntxiv. Raws li koj tus kws kho mob qhia, yuav tsum tau sau cov zis txhua hnub. Qhov no yog ua los ntawm kev sau txhua feem ntawm cov zis 24 teev hauv ib hnub thiab muab tso rau hauv ib lub thawv kom kwv yees tias tus menyuam poob protein ntau npaum li cas. Yog tias pom muaj protein ntau ntau dua 50 mg / kg / hnub, nephrotic proteinuria raug pom. Kev kuaj ntshav yuav tsum ntsuas qhov concentration ntawm albumin, tag nrho cov protein, urea, creatinine, calcium, cholesterol. Cov ntshav coagulation yuav tsum tau soj ntsuam raws li qhov pib ntawm nephrotic syndrome predisposing rau thrombosis, uas tuaj yeem ua rau embolism hauv cov hlab ntsha.
Kev kuaj mob raum - raum biopsy
Ib lub raum biopsy yuav tshem tawm ib feem me me ntawm lub raum cuam tshuam. Hauv cov menyuam yaus (los ntawm 6 txog 7 xyoos), cov txheej txheem yog ua raws li tshuaj loog hauv zos raws li kev taw qhia ultrasound. Tus me nyuam yuav tsum dhau ntawm lub plab khoob. Ua ntej tus txheej txheem, nws yog ib qho tsim nyog yuav tsum tau ua txoj kev tshawb fawb txog ntshav txhaws. Biopsy tsuas tuaj yeem ua taucov me nyuam txhaj tshuaj tiv thaiv kab mob siab B (tom qab tshuaj tiv thaiv kab mob titration). Yog tias cov tshuaj tiv thaiv kab mob tiv thaiv qis dua, cov niam txiv yuav tsum txhaj tshuaj tiv thaiv tus menyuam tiv thaiv kab mob siab B. Nyob rau hauv cov menyuam yaus (tsawg dua 6 xyoos), yuav tsum tau txhaj tshuaj loog kom tshem tawm cov ntaub so ntswg los ntawm lub raum.
Ua ntej kev kuaj ntshav biopsy, tus me nyuam niam txiv raug hais kom pom zoo rau qhov kev ntsuam xyuas. Zoo li txhua txoj kev cuam tshuam, ib feem me me ntawm lub raum biopsies yog lub nra hnyav nrog cov teeb meem, feem ntau los ntshav thiab hematoma tsim nyob ib ncig ntawm lub raum. Tom qab kuaj pom tus me nyuam, tus me nyuam yuav tsum pw ntawm lawv nraub qaum rau 12 teev tom ntej no kom txo tau qhov mob.
Nyob rau hauv cov menyuam yaus feem ntau, thawj qhov tshwm sim ntawm nephrotic syndrome tsis xav tau lub raum biopsy. Qhov no txhais tau hais tias nyob rau hauv lub tshuab kuaj kab mob, cov qauv ntawm lub raum tuaj yeem pom tseeb yam tsis muaj qhov txawv txav.
Kuj, muaj cov cim qhia rau kev kuaj ntshav thaum:
- lub hnub nyoog ntawm tus menyuam thaum lub sijhawm muaj mob (tsawg dua 1 xyoos lossis laus dua 12 xyoos);
- kho mob-resistant nephrotic syndrome;
Yuav tsum kuaj xyuas qhov hloov pauv parenchymal tom qab kev kho mob ntev thiab thaum lub raum ua haujlwm tsis zoo
Kev kho mob glomerulonephritis nyob rau hauv cov menyuam yaus
Kev kho mob feem ntau pib hauv tsev kho mob. Nyob rau hauv cov ntaub ntawv ntawm nephrotic syndrome nrog loj edema, glucocorticosteroids (methylprednisolone) yog muab intravenously. Qhov ncauj prednisone yog siv yog tias cov protein poob me me thiab tsis nrog los ntawm qhov mob hnyav.
DavTus qauv lees paub ntawm thawj kab kev kho mob rau nephrotic syndrome yog 6 lub hlis ntawm kev kho glucocorticoid hauv kev txo koob tshuaj. Cov kev tswj hwm no tau hloov kho nyob rau hauv rooj plaub ntawm steroid dependence los yog tsis kam. Raws li nyob rau hauv cov ntaub ntawv ntawm rov tshwm sim, steroid dependence, thiab kuj nyob rau hauv cov me nyuam uas muaj glomerulonephritis, nyob rau hauv kev kho mob, cov tshuaj tau hloov mus rau lwm tus neeg, xws li Cyclophosphamide - mus txog 3 lub hlis, Chlorambucil - noj mus txog rau 3 lub hlis, Cyclosporine-A yog siv rau xyoo. los yog mycophenolate mofetil - tsawg kawg yog ib xyoos.
Ntxiv rau cov kev kho mob tseem ceeb (glucocorticosteroids), kev kho cov tsos mob yog nqa tawm kom tshem tawm cov teeb meem tshwm sim los ntawm cov proteinuria hnyav. Nyob rau hauv cov ntaub ntawv ntawm kev poob ntawm cov protein ntau nrog kev txo qis hauv cov concentration ntawm albumin hauv cov ntshav, cov tshuaj infusions ntawm 20% kev daws teeb meem ntawm albumin yog siv nrog kev kho diuretic (furosemide). Kev kho diuretic yog muab rau cov neeg mob edema nrog ntshav calcium theem, txo cov roj cholesterol (statins), anticoagulant prophylaxis, thiab kev kho mob ntshav siab yog tias muaj. Nrog kev txo qis ntawm calcium, calcium thiab vitamin D3 raug qhia. Tom qab ploj ntawm cov tsos mob ntawm cov proteinuria, kev kho mob ntxiv tuaj yeem ua tom tsev.
Cov lus qhia kho mob rau kev kho mob glomerulonephritis hauv menyuam yaus:
Kev txo cov koob tshuaj lossis tso tseg tag nrho (tsis muaj kev pom zoo los ntawm kws kho mob ua ntej) tuaj yeem ua rau muaj kev phom sij heev. Qhov no tuaj yeem ua rau rov ua dua, rov kho dua tshiab, thiab kho cov hlab ntsha. Qhov no feem ntau siv rau prednisolone,cyclosporine A los yog mycophenolate mofetil
Txoj cai tseem ceeb rau kev kho cov menyuam yaus uas muaj glomerulonephritis xav tau kev kho mob mus ntev yog ua raws li tus kws kho mob cov lus pom zoo
Cov menyuam yaus yuav tsum tau txais kev saib xyuas tshwj xeeb nephrology nrog kev saib xyuas ib ntus hauv chav kho mob nephrology. Thaum kho tus mob glomerulonephritis hauv cov menyuam yaus hauv tsev, yuav tsum tau kuaj cov zis ib ntus (kev kuaj dav dav). Yog tias koj mob o tshiab, kuaj koj cov zis tam sim ntawd, ntsuas cov proteinuria, thiab tiv tauj koj tus kws kho mob lossis chaw kho mob menyuam yaus. Nws yuav tsum nco ntsoov tias txawm tias tus kab mob banal tuaj yeem ua rau muaj kev rov tshwm sim ntawm nephrotic syndrome (xws li cov hniav tsis kho nrog o), uas yog, qhov rov tshwm sim ntawm edema thiab txo cov zis. Tom qab ntawd koj yuav tsum txwv cov kua dej kom tsis txhob o.
Cov menyuam yaus yuav tsum zam txhua yam kev kis kab mob thaum kho nrog koob tshuaj ntau ntawm glucocorticoids thiab tshuaj tiv thaiv kab mob. Nyob rau hauv cov ntaub ntawv ntawm kev txhaj tshuaj, tsis txhob hnov qab siv cov kev npaj uas muaj cov kab mob nyob. Kev siv cov koob tshuaj ntau ntawm glucocorticoids thiab cov tshuaj tiv thaiv kab mob tuaj yeem txo qhov ua tau zoo ntawm cov tshuaj tiv thaiv, thiab kev txhaj tshuaj tiv thaiv nws tus kheej tuaj yeem ua rau rov ua haujlwm dua. Kev siv daim ntawv qhia hnub txhaj tshuaj yog qhov nyuaj thiab txhua lub sijhawm yuav tsum tau sab laj nrog kws kho mob nephrologist.
Feem ntau ntawm cov teeb meem uas tshwm sim thaum lub sij hawm nephrotic syndrome yog txuam nrog kev kho mob mus sij hawm ntev glucocorticoid (lub cev luv luv, rog, ntshav qab zib, cataracts, hloov pob txha ntom) lossis yog qhov tshwm sim ntawm kev poob ntawm cov protein ntau hauv cov zis. (hypercoagulability,hypocalcemia, hypercholesterolemia).
Kev zam txim thiab rov qab
Nyob rau hauv 90% ntawm cov menyuam yaus, kev tso tawm ntawm tus kabmob (tso zis tsis muaj protein ntau) tau pom nrog thawj tus mob nephrotic. 20% ntawm cov menyuam no tsis muaj kev rov qab los, 40% muaj qhov tsis tshua muaj tshwm sim, thiab 30% muaj tus kab mob ntau zaus (steroid dependence). 10% ntawm cov menyuam yaus raug kuaj pom tias muaj kev tiv thaiv steroid. Cov kev mob tshwm sim rau chav kawm ntawm nephrotic syndrome yog nyob ntawm cov lus teb rau kev kho mob. Kev tsis haum rau cov qauv kev kho mob thiab kev siv tshuaj rau cov menyuam yaus uas muaj glomerulonephritis yog ib qho kev pheej hmoo rau kev loj hlob ntawm lub raum tsis ua haujlwm. Hauv qhov xwm txheej hnyav, nws yog ib qho tseem ceeb kom cia siab tias nephrotic syndrome yuav nrog tus neeg mob mus tas li. Qee cov menyuam yaus (nyob ntawm seb hom kab mob) tuaj yeem tsim kab mob raum ntev thiab txog li 25% yuav tsim lub raum tsis ua haujlwm kawg uas yuav tsum tau lim ntshav lossis hloov lub raum.
YGlomerulonephritis yog ib yam kab mob txiav txim siab caj ces
Glomerulonephritis tuaj yeem yog kab mob hauv lub cev. Qee zaum nws mob hnyav thiab tshwm sim tam sim tom qab yug me nyuam. Cov menyuam yaus feem ntau yug ntxov ntxov, nrog lub plab loj thiab cov leeg tsis muaj zog. Raws li qhov tshwm sim ntawm kev poob loj heev ntawm cov protein nyob rau hauv cov zis, nce edema tshwm sim thiab kev pheej hmoo ntawm cov teeb meem thrombotic thiab kis kab mob. Yog tias tsis muaj protein ntau tswj tsis tau, ob lub raum yuav tsum tau muab tshem tawm thiab kev kho mob pib nrog kev lim ntshav (feem ntau yog peritoneal dialysis). Tom qab ncav cuag qhov hnyav ntawm 7-8 kg, hloov lub raum tuaj yeem ua tau. Hauv qee qhovCov teeb meem ntawm caj ces txiav txim siab nephrotic syndromes, chav kawm tsis yog qhov txaus ntshai. Cov tsos mob tuaj yeem tshwm sim thaum muaj hnub nyoog sib txawv thiab zoo ib yam li cov uas pom muaj nyob rau hauv lwm hom glomerulonephritis, piv txwv li edema, proteinuria, thiab lwm yam. Ib qho ntawm cov tsos mob ntawm caj ces nephrotic yog tsis kam mus rau kev siv tshuaj kho mob.
Tam sim no koj paub tias cov tsos mob thiab kev kho mob ntawm glomerulonephritis hauv cov menyuam yaus ua li cas, thiab qhov txiaj ntsig ntawm kev kho tsis raug rau tus neeg mob yuav ua li cas.
