Nyob ntiaj teb no, kev tshawb fawb tsis nyob twj ywm. Cov kab mob tau ua tib zoo kawm, thiab cov kws tshawb fawb tab tom nrhiav txoj hauv kev los tawm tsam lawv. Cov kws kho mob feem ntau raug txiav txim kom ua qhov kev ntsuam xyuas uas tsis meej rau cov neeg zoo tib yam, tab sis nws yog qhov tshwm sim uas tuaj yeem lees paub lossis tsis lees paub tus kws kho mob qhov kev ntshai. Yog li kev tsom xam rau LDH, thiab tshwj xeeb tshaj yog nce lactate dehydrogenase, hais ntau heev. Dab tsi yog nws, thiab dab tsi yog qhov tshwm sim, peb yuav tham ntxiv.
LDH yog dab tsi
Lactate dehydrogenase yog ib qho ntawm cov enzymes uas qhia tias muaj cov hlwb puas. Nws pom ob qho tib si hauv cov ntshav thiab hauv cov ntaub so ntswg sib txawv. Nyob rau hauv tus txheej txheem ntawm kev ua pa, lactic acid ntsev yog tsim nyob rau hauv lub hlwb. Lactate dehydrogenase txhawb nws txoj kev hloov mus rau pyruvic, uas koom nrog hauv cov txheej txheem oxidation siab. Nws pab txhawb kev tso tawm sai ntawm lub zog ntawm cov piam thaj, uas yog qhov tsim nyog rau cov leeg nqaij contraction, ntws ntawm cov txheej txheem biochemical. Qhov tshwm sim yog cov khoom uas yooj yim tshem tawm ntawm lub cev - carbon dioxide thiab dej. Yog tias cov pa oxygen tsis txaus, cov enzymes sib sau ua ke, pathologies tshwm sim uas ua rau cov cell lwj. Lawv yuav coj muslactate dehydrogenase nce siab. Qhov ntsuas no yog qhov nkag siab zoo rau kev puas tsuaj ntawm cov qauv cellular.
Lactate dehydrogenase, yog tias npaj kom txo qis, pom nyob rau hauv cov kabmob thiab cov ntaub so ntswg hauv qab no:
- Nyob raum.
- Lub plawv mob.
- pob txha pob txha.
- Pancreas.
- Spleen.
- Lub chaw kuaj tshuaj ntawm peb lub cev - lub siab.
- Luag.
- Nyob hauv ntshav.
LDH hom
Lub enzyme lactate dehydrogenase muaj ntau hom kev sib txawv ntawm ib leeg los ntawm isoenzymes, thiab lawv muaj nyob hauv cov ntaub so ntswg sib txawv. Nyob ntawm seb qhov concentration ntau dua ntawm isoenzyme hauv ib lub cev, muaj cov enzyme no:
- LDH-1 - feem ntau hauv lub plawv thiab cov qe ntshav.
- 2 - hauv leukocytes.
- 3 - hauv lub ntsws.
- LDH - 4 - feem ntau ntawm tag nrho cov hauv lub raum, placenta, pancreas.
- 5 - pom nyob rau hauv daim siab thiab cov leeg nqaij striated.
Ua tsaug rau qhov no, nws tuaj yeem txiav txim siab, vim yog isoenzyme qib ntawm LDH nce, thiab txiav txim siab tus kab mob.
Thaum qhov kev xeem no raug txiav txim
Muaj ntau yam xwm txheej uas yuav tsum tau tswj hwm qib ntawm LDH:
- Nyob rau hauv kab mob hepatobiliary system.
- After myocardial infarctions.
- Thaum kuaj pom cov qog ntau yam.
- Yog tias tsim nyog los txiav txim siab hom ntshav ntshav.
- Thaumkab mob nrog nce hemolysis.
- Nrog qhov mob hnyav hauv thaj tsam hauv siab.
- Yog tias muaj kev puas tsuaj rau lub siab lossis lub raum.
- Kom tshuaj xyuas cov ntaub so ntswg thiab cov leeg tom qab raug mob lossis kab mob.
Kev cuam tshuam ntawm cov txiaj ntsig ntawm kev tshuaj ntsuam
Yog tias tus kws kho mob xav tias koj tau nce lactate dehydrogenase, tsuas yog kev tshuaj ntsuam tuaj yeem lees paub lossis lees paub qhov no.
Kev kuaj ntshav rau LDH yog noj thaum sawv ntxov ntawm lub plab khoob. Ntshav yog muab los ntawm cov hlab ntsha. Ua ntej mus rau chav kho mob, tsis tas yuav tsum tau noj zaub mov tshwj xeeb. Nws tsuas yog tsim nyog kom paub tias muaj ntau yam uas tuaj yeem cuam tshuam qhov tshwm sim. Dab tsi tuaj yeem cuam tshuam qhov raug ntawm qhov kev tshuaj ntsuam xyuas:
- Kev noj cov vitamin C tuaj yeem txo cov ntshav LDH.
- Kev siv cov tshuaj electropulse nyob rau ua ntej ntawm qhov kev xeem.
- cov teeb meem tawv nqaij.
- ntshav cawv cov ntsiab lus.
- YThrombocytosis.
- Kev siv hemodialysis.
- Qee yam tshuaj xws li Aspirin, Mithramycin, tshuaj loog, tshuaj fluoride tuaj yeem nce qib enzyme.
- kev tawm dag zog ntau dhau.
Cov yam ntxwv no tuaj yeem cuam tshuam qhov tshwm sim, tab sis qhov no tsis txhais tau tias muaj cov txheej txheem pathological hauv lub cev.
Ua ntej koj paub cov ntsiab lus ntawm cov enzyme hauv koj cov ntshav, koj yuav tsum sab laj nrog koj tus kws kho mob, cov tshuaj twg yuav tsum tau txiav ua ntej mus kuaj.
Nws yog ib qho tseem ceeb heev rau kev thauj thiab khaws cov ntshav pub dawb, vim tsis ua raws li cov cai yuav ua rauhemolysis ntawm cov ntshav, thiab yog li ntawd, nce lactate dehydrogenase.
LDH cov qauv ntsuas rau cov menyuam yaus thiab cov neeg laus
Lactate dehydrogenase qib hloov pauv raws hnub nyoog. Tus neeg laus dua, lawv qis dua. Yog li, LDH concentration:
- Cov Me Nyuam Tshiab - txog 28.9 mkat / l.
- Txij 1 xyoos txog 3 xyoos - txog 14, 2 mkat/l.
- Rau cov tub hluas hnub nyoog 7 txog 12 xyoos - txog 12.7 mkat/l.
- Cov menyuam yaus hnub nyoog 7 xyoo txog 12 xyoos - txog 9.67 mkat/l.
- txiv neej - txog 11.4 mkat/l.
- Women - mus txog 7.27 mkat/l.
LDH qib yuav siab dua lossis qis dua li qub.
Ntau lactate dehydrogenase - ua rau
Ntau dua tau pom nyob rau hauv cov poj niam cev xeeb tub thiab ua haujlwm lub cev ntau dhau.
Yog tias lactate dehydrogenase nce siab vim qhov kev soj ntsuam. Cov laj thawj rau qhov no yog kev txhim kho ntawm cov xwm txheej hauv qab no:
- mob plawv mob plawv.
- kab mob siab viral.
- Cirrhosis ntawm daim siab.
- Oncology.
- Tus mob pancreatitis.
- Pathological kab mob ntawm lub raum.
- Anemia.
- Leukemia.
- Cov xwm txheej uas nthuav dav ntawm tes tshwm sim: poob siab, hypoxia hnyav, kub hnyiab ntawm thaj chaw loj.
- kev raug mob loj.
- Kab mob ntawm cov leeg nqaij.
Txawm li cas los xij, tsis yog qhov kev tshuaj ntsuam no tsuas pom pom muaj cov kab mob hauv lub cev. Kev tshawb nrhiav ntxiv yog xav tau. Los ntawm kev kawm txog cov haujlwm ntawm isoenzymes, tus kws tshaj lij yuav tuaj yeem txiav txim siab qhov chaw ntawm tus kabmob.
Meaning of indicatorsLDH isoenzymes Y
Yog tias peb saib ze dua ntawm qhov nce hauv lactate dehydrogenase ntawm qee yam, peb tuaj yeem txiav txim siab qhov foci ntawm qhov tshwm sim tshwm sim.
Ntau LDH-1 lossis LDH-1 / LDH-2 piv tau ua tau raws li cov xwm txheej hauv qab no:
- mob plawv nres.
- YHemolytic megaloblastic anemia.
- Acute raum necrosis.
- Nyob rau hauv lub xub ntiag ntawm qog ntawm txiv neej thiab poj niam qhov chaw mos.
Qhov nce hauv LDH-5 yog qhov raug rau:
- kab mob siab.
- Rake.
- Skeletal leeg raug mob.
nce hauv LDH-2 thiab LDH-3 feem ntau pom thaum:
- mob leukemia.
- Chronic granulocytosis.
nce LDH-3, tej zaum qee qhov LDH-4 thiab LDH-5 feem ntau yog tam sim no:
- Kidney disease.
- YPulmonary embolism.
- Lub plawv tsis ua hauj lwm nrog rau lub ntsws.
LDH-4 nce LDH-5 kuaj pom yog tias kuaj tau:
- Impaired ncig vim lub plawv tsis muaj zog.
- mob siab.
- mob nqaij leeg.
LDH hauv menyuam yaus
Thaum tham txog menyuam yaus, koj yuav tsum xav txog lub hnub nyoog ntawm tus menyuam. Hauv cov menyuam yaus, qib LDH siab dua. Tsis tas li ntawd, ua ntej koj mus ntsib kws kho mob, koj yuav tsum taug qab cov tshuaj uas tus menyuam noj thiab saib xyuas nws lub cev ua si. Yog tias lactate dehydrogenase nce siab hauv tus menyuam, qhov ua rau tuaj yeem tshwm sim los ntawm ib qho ntawm cov kab mob tau piav qhia saum toj no. Nws yuav tsum tau borne nyob rau hauv lub siab hais tias yog hais tias tus me nyuam yog tsis haum, qhov no kuj muaj feem xyuam rau qhov tshwm sim,tshwj xeeb tshaj yog nrog mob hnyav thaum yau los yog mob ntsws asthma bronchial. Kev raug mob thiab nqaij ntshiv tuaj yeem cuam tshuam qhov kev soj ntsuam, nrog rau qhov muaj ntshav tsis txaus hauv tus menyuam.
Yog tias thawj qhov tshwm sim siab dua li qub, koj yuav tsum rov sim dua kom paub tseeb tias nws yog. Yog tias, txawm li cas los xij, lactate dehydrogenase nce siab hauv tus menyuam, yog li kev kuaj xyuas tiav yog tsim nyog. Qhov ntsuas no ib leeg tsis muab txoj cai los kuaj xyuas zaum kawg thiab sau ntawv kho mob.
Kev kho kab mob thiab hloov LDH
Yog tias lactate dehydrogenase nce siab, kev kho tus kab mob tuaj yeem maj mam coj qhov ntsuas no rov qab mus rau qhov qub.
- Hauv lub raum mob hnyav, LDH nce ntxiv, nyob rau hauv cov kab mob ntev nws tseem zoo li qub. Nce tom qab hemodialysis.
- Nrog rau lub siab thiab kab mob siab ntev, LDH qhov tseem ceeb yog qhov qub, thaum lub sijhawm tus kab mob hnyav zuj zus, qhov txiaj ntsig nce ntxiv.
- Rau anemia, LDH yog siv rau kev kuaj mob sib txawv.
- Nrog lub plawv nres, LDH nce, thiab tom qab 10-14 hnub nws rov zoo li qub. Kev tswj hwm ntawm cov enzyme no tso cai rau tus kws kho mob los soj ntsuam cov kev kho mob.
Yog tias thaum pib ntawm tus kab mob lactate dehydrogenase nce ntxiv, tom qab ntawd nrog kev kho mob zoo ntawm cov ntshav ntshav, leukemia, qog nqaij hlav, LDH kev ua haujlwm txo qis.
Ntawm no yog qhov kev tshuaj ntsuam tsis yooj yim uas peb feem ntau tsis paub txog. Thiab nws, nws hloov tawm, tuaj yeem qhia ntau yam txog tus kws kho mob.
