Coombs 'test yog ib qho kev sim kuaj tshwj xeeb uas kuaj pom cov tshuaj tiv thaiv muaj nyob hauv cov ntshav plasma lossis ntawm cov qe ntshav liab. Cov txheej txheem no tso cai rau kev kuaj xyuas lub cev tiv thaiv kab mob hemolytic anemia, suav nrog hauv cov menyuam yug tshiab, nrog rau kev kuaj xyuas cov tshuaj tiv thaiv hemolytic. Kev kuaj Coombs nquag siv hauv cov tshuaj forensic thiab kev tshawb fawb caj ces los txiav txim siab erythrocyte antigens. Ua raws li tag nrho cov cai rau kev ua raws li qhov kev tshuaj ntsuam no tso cai rau koj kom tau txais txiaj ntsig zoo tshaj plaws.
Lub hom phiaj ntawm kev kuaj tshuaj antiglobulin
Direct Coombs kuaj tso cai rau koj los kuaj xyuas cov tshuaj tiv thaiv erythrocyte uas tau kho ntawm erythrocytes. Cov tshuaj tiv thaiv zoo hauv qhov kev tshawb fawb no qhia txog kev txhim kho autoimmune hemolytic anemia. Nws yuav tsum raug sau tseg tias qhov tshwm sim tsis zoo tsis suav nrog qhov muaj tus kab mob autoimmune, txij li cov tshuaj tiv thaiv feem ntau nyob hauv daim ntawv dawb, uas yog, lawv tsis muaj kev sib txuas nrog cov qe ntshav liab. Nyob rau hauv tas li ntawd, nws yog advisable mus ua ib tug indirect Coombs xeem, uas yuav tso cai rau koj mus txiav txim lub autonomous.tshuaj hauv ntshav.
Kev tshuaj ntsuam ua li cas?
З
Kev kuaj ntshav Venous los ntawm tus neeg mob tau ua thaum sawv ntxov ntawm lub plab khoob, txawm tias tsis muaj qhov tseem ceeb cuam tshuam rau qhov kawg ntawm qhov kev sim no tau pom. Nws raug tso cai khaws cov khoom noj ntawm qhov kub ntawm 2 txog 8 ° C tsis pub ntev tshaj xya hnub. Txhawm rau kom cov txiaj ntsig ntawm qhov kev sim no kom raug raws li qhov ua tau, tag nrho cov ntshav yuav tsum raug xa mus rau chav kuaj hauv thawj ob teev. Qhov zoo tshaj plaws, kev kuaj Coombs yuav tsum pom qhov tshwm sim tsis zoo, uas qhia tau tias tsis muaj kev hloov pauv ntawm hemolytic hauv lub cev.
Transcript of tag nrho
Coombs xeem yog ib txoj kev tshawb fawb siv sijhawm ntau uas yuav tsum tau ua tib zoo saib xyuas thiab ua haujlwm raug. Thaum siv qhov kev sim no, tej zaum yuav muaj qee qhov teeb meem uas cuam tshuam nrog kev txhais lus tsis raug ntawm qhov kawg tshwm sim vim qhov tsis muaj zog ntawm cov tshuaj tiv thaiv zoo. Nws yuav tsum tau muab sau tseg tias qhov tsis ntseeg ntawm qhov kev tshuaj ntsuam - uas yog, qhov zoo Coombs kuaj - tej zaum yuav tshwm sim los ntawm ineffective ntxuav ntawm erythrocytes, tiv nrog ib tug greasy nto, nrog rau neutralization ntawm antiglobulin reagents los ntawm cov khoom
serum. Lwm qhov tsis zoo ntawm txoj kev tshawb fawb no yog qhov tsis ruaj khov ntawm cov khoom siv, qhov chaw cia uas muaj qee yam nta.
Cov txiaj ntsig tsis zoo-tsis zoo yuav tshwm sim los ntawm kev co ntau dhau ntawm RBC raug ncua thaumresuspension. Cov txiaj ntsig tsis zoo kuj tseem tuaj yeem yog vim muaj cov tshuaj tiv thaiv kab mob ntxiv rau cov tshuaj tiv thaiv kab mob uas adsorb thaum lub sij hawm incubation ntawm qhov chaw kuaj erythrocytes, uas ua rau pom qhov tshwm sim zoo. Yog tias cov qauv kuaj tau raug ntxuav kom huv si thiab cov tshuaj tiv thaiv raug tswj, cov kev tsis txaus no tuaj yeem tshem tawm tau yooj yim, uas yuav ua rau kom tau txais txiaj ntsig zoo tshaj plaws Coombs xeem qhov tseem ceeb.
