Kev noj ntau dhau ntawm dipyrone: qhov tshwm sim. Analgin: cov lus qhia rau kev siv, mechanism ntawm kev txiav txim, muaj pes tsawg leeg, cov lus qhia

Cov txheej txheem:

Kev noj ntau dhau ntawm dipyrone: qhov tshwm sim. Analgin: cov lus qhia rau kev siv, mechanism ntawm kev txiav txim, muaj pes tsawg leeg, cov lus qhia
Kev noj ntau dhau ntawm dipyrone: qhov tshwm sim. Analgin: cov lus qhia rau kev siv, mechanism ntawm kev txiav txim, muaj pes tsawg leeg, cov lus qhia

Video: Kev noj ntau dhau ntawm dipyrone: qhov tshwm sim. Analgin: cov lus qhia rau kev siv, mechanism ntawm kev txiav txim, muaj pes tsawg leeg, cov lus qhia

Video: Kev noj ntau dhau ntawm dipyrone: qhov tshwm sim. Analgin: cov lus qhia rau kev siv, mechanism ntawm kev txiav txim, muaj pes tsawg leeg, cov lus qhia
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Anonim

Analgin yog kab tias muaj npe nrov tshaj plaws uas tsis yog-steroidal tshuaj tiv thaiv kab mob. Nws zoo tshem tawm qhov mob ntawm cov leeg nqaij thiab lub paj hlwb, thiab tseem ua rau qhov kub thiab txias.

Tab sis cov tshuaj no puas tuaj yeem tsim teeb meem? Puas muaj kev noj tshuaj ntau dhau ntawm analgin tshwm sim? Thiab dab tsi yog qhov txaus ntshai ntawm kev noj tshuaj ntau dhau? Cov lus nug no txaus siab rau ntau tus, yog li nws tsim nyog teb lawv tam sim no.

Overdose ntawm analgin: qhov tshwm sim
Overdose ntawm analgin: qhov tshwm sim

Kev sib xyaw thiab kev ua haujlwm

Kuv xav pib nrog qhov no. Cov muaj pes tsawg leeg ntawm analgin yog yooj yim, nws muaj tsuas yog ib tug active ingredient - metamizole sodium, uas yog ib tug haib analgesic thiab antipyretic teej tug mus rau pawg ntawm pyrazolones.

Kuj nyob rau hauv cov ntsiav tshuaj npaj muaj auxiliary, pharmacologically nruab nrab tshuaj - hmoov qab zib, qos starch, talc thiab calcium stearate. Cov tshuaj, tsim nyob rau hauv ampoules, tsuas muaj metamizole sodium.

Yuav ua li cas yog lub mechanism ntawm kev txiav txim ntawm analgin? Cov tshuaj no txo qis kev tsim ntawm bradykinins, dawb radicals, qee cov prostaglandins thiab endoperoxides. Nws kuj inhibits lipid peroxidation thiab muaj kev cuam tshuam rau kev ua haujlwm ntawm cyclooxygenase. Tsis tas li ntawd, cov cuab yeej nce qhov pib ntawm excitability thiab blocks mob impulses. Lawv tsuas tsis hla Burdakh thiab Gaulle pob.

Indications rau kev siv ntawm analgin
Indications rau kev siv ntawm analgin

Thaum twg tshuaj pab?

Cov lus qhia rau kev siv analgin kuj tsim nyog teev. Cov tshuaj no tuaj yeem pab tau yog tias ib tus neeg tab tom ntsib ib qho ntawm cov hauv qab no:

  • Toothache thiab mob taub hau.
  • biliary thiab lub raum colic.
  • Mob los ntawm kub hnyiab, raug mob.
  • Myalgia, neuralgia, menalgia.
  • Mob tom qab phais.
  • Fever.
  • Kub kub tsis teb rau lwm yam kev ntsuas.
  • mob hnyav lossis mob hnyav, uas lwm yam kev kho mob tsis tuaj yeem ua tsis tau.

Nws yog ib qho tseem ceeb uas yuav tsum nco ntsoov tias kev qhia txog cov tshuaj parenterally yog qhia tsuas yog tias nws ua tsis tau nws nkag mus (los ntawm lub qhov ncauj).

Kev sib xyaw ntawm analgin
Kev sib xyaw ntawm analgin

Ua rau overdose ntawm analgin

Thiab lawv yuav tsum tau ua tib zoo saib. Raws li txoj cai, tshuaj lom neeg muaj peev xwm ua tau rau cov laj thawj hauv qab no:

  • Kev tsim txom tshuaj rau qhov mob ntev los ntawm qee yam mob mus ntev.
  • Kev siv tshuaj txhaum cai ntawm lub raum thiab lub siab ua haujlwm.
  • Siv tshuaj nrogtshuaj teej tug mus rau pawg ntawm barbiturates. Cov no suav nrog Anaprilin, Codeine, thiab ntau lwm yam tshuaj tiv thaiv. Lawv txhim kho qhov kev txiav txim ntawm analgin. Yog li kev siv tshuaj, txawm tias nyob rau hauv cov koob tshuaj kho mob, yuav ua rau qaug cawv.

Yog li ntawd, ua ntej siv cov tshuaj tiv thaiv kab mob nrov no, koj yuav tsum sab laj nrog koj tus kws kho mob.

Cov lus qhia rau kev siv

Txhawm rau tiv thaiv kev lom nrog analgin, nws yuav tsum tau kawm cov lus qhia rau cov tshuaj. Txawm hais tias nws hais tias qhov ntau npaum li cas nyob ntawm qhov mob ua npaws thiab mob, qhov no tsis txhais hais tias koj tuaj yeem noj 5 ntsiav tshuaj ib zaug thiab ua siab ntev rau koj txoj kev noj qab haus huv.

Yog li ntawd, nws yog ib qho tseem ceeb kom nco ntsoov cov ntaub ntawv hais txog qhov pom zoo thiab ntau npaum li cas. Raws li cov lus qhia rau analgin, nws yog:

  • Rau cov menyuam yaus hnub nyoog 10 txog 14 xyoos hnyav ntawm 32 txog 53 kg - 1 ntsiav tshuaj ib zaug thiab 4 - siab tshaj.
  • Rau cov neeg laus thiab cov tub ntxhais hluas hnub nyoog qis dua 15 xyoos thiab hnyav dua 53 kg - 1-2 ntsiav tshuaj ib zaug thiab nce txog 8 qhov siab tshaj.

Tsis muaj teeb meem koj yuav tsum noj ob peb daim ib zaug rau qhov txiaj ntsig sai dua. Cov ntsiav tshuaj pib ua 30-60 feeb tom qab noj. Yog tias cov tshuaj tau muab tshuaj rau niam txiv, qhov mob yuav pib sai dua.

Los ntawm txoj kev, yog tias koj txiav txim siab txhaj tshuaj, koj yuav tsum ua tib zoo saib cov lus pom zoo hauv qab no: rau cov menyuam yaus - 500-2000 mg, rau cov neeg laus - 1000-4000 mg.

Symptoms

Cov tsos mob hauv qab no qhia tias kev noj tshuaj ntau dhau ntawm analgin:

  • Kev qaug zog.
  • kiv taub hau.
  • Ntaus thiab ntuav.
  • Nyob hauv taub hau.
  • Tinnitus.
  • Tachycardia.
  • Psychomotor agitation.
  • Ntxhais tawv nqaij.
  • Hypothermia.
Kev pab thawj zaug rau kev noj tshuaj ntau dhau ntawm analgin
Kev pab thawj zaug rau kev noj tshuaj ntau dhau ntawm analgin

Hauv qhov xwm txheej hnyav, qhov tshwm sim ntawm kev noj ntau dhau ntawm dipyrone yog convulsions uas npog cov leeg ua pa, nrog rau cov zis liab lossis liab liab. Kev xyaum paub txog cov xwm txheej ntawm cyanosis thiab tom qab immersion nyob rau hauv lub coma, mus txog 4-5 cov ntsiab lus ntawm Glasgow scale.

Kev siv tshuaj ntev ntev hauv ntau qhov ua rau inhibition ntawm cov txheej txheem hematopoiesis. Qhov no ua rau granulocytopenia (qhov txo qis hauv granulocytes hauv cov ntshav) thiab agranulocytosis (qis ntawm cov qe ntshav dawb).

Tseem muaj teeb meem nrog rau txoj hnyuv - gastritis, ulcers ntawm txoj hnyuv thiab plab, ua txhaum ntawm cov txheej txheem ntawm kev tsim cov hydrochloric acid. Qhov no tshwm sim los ntawm cov tsos mob hauv qab no:

  • Burp.
  • Tsis xis nyob hauv cheeb tsam epigastric.
  • Bloating.
  • x

  • Kev tshaib kev nqhis nrog mob.
  • plab hnyuv los ntshav.

Nws tseem yuav tsum tau muab sau tseg tias tshuaj lom analgin ua rau muaj kev fab tshuaj. Lawv tuaj yeem tshwm sim hauv ntau hom - khaus khaus, ua xua edema, lossis txawm tias anaphylactic shock.

Qhov tshwm sim ntawm overdose ntawm analgin
Qhov tshwm sim ntawm overdose ntawm analgin

Txhais tau

Thiab yuav tsum tau qhia txog lawv, txij li peb tab tom tham txog kev noj tshuaj ntau dhau ntawm analgin. Ua ntej tshaj plaws, nws yuav tsum tau muab sau tseg tias cov tshuaj noua rau mob hnyav rau cov hlab ntsha, lub siab, ob lub raum, circulatory system thiab ntsws (qee zaum).

Hauv cov ntshav, cov ntshav platelets thiab leukocytes txo qis heev. Raws li qhov tshwm sim, lub cev tiv thaiv kab mob tsis muaj zog, thiab lub cev tsis tuaj yeem tuav rov qab microscopic abodes. Vim li no, o ntawm mucous daim nyias nyias thiab cov ntaub so ntswg necrosis tshwm sim, ulcers pib tsim nyob rau hauv cov hnyuv thiab plab..

Cov mucous ntawm qhov ncauj kab noj hniav kuj raug cuam tshuam, uas ua rau tonsillitis, o ntawm cov pos hniav. Nyob rau hauv lub ntsws, bronchi, trachea, thiab txawm nyob rau hauv lub urinary ib ntsuj av, lesions kuj tsim.

Thaum mob hnyav, vim qhov txo qis hauv platelets, tuaj yeem los ntshav. Tsis tas li ntawd feem ntau tsim bronchitis, tracheitis thiab pharyngitis, tsis haum rau kev kho mob. Nyob rau hauv parallel, muaj ib tug txo nyob rau hauv tso zis. Yog tias koj dhau cov zis rau kev tshuaj xyuas, cov kab mob thiab cov protein ntau yuav pom hauv nws.

Tab sis, tej zaum, ib qho ntawm qhov tshwm sim loj tshaj plaws ntawm kev noj tshuaj ntau dhau ntawm analgin yog ua rau lub siab lom. Qhov no yog pov thawj los ntawm yellowing ntawm daim tawv nqaij, mucous daim nyias nyias, khaus thiab tsub zuj zuj ntawm bilirubin nyob rau hauv cov ntshav.

Kev pab ib zaug

Cov lus qhia rau kev siv cov tshuaj analgin, cov tsos mob ntawm cov tshuaj lom thiab cov txiaj ntsig tau piav qhia saum toj no. Tam sim no peb yuav tsum tham txog yuav ua li cas thaum muaj kev lom.

Ua ntej lub tsheb thauj neeg mob tuaj txog, uas yuav tsum xub hu ua ntej, koj yuav tsum tau ua plab hnyuv - haus li ib nrab ib liter dej thiab ua rau ntuav. Rov ua qhov kev txiav txim ntau zaus.

Yog ib tug neeg txoj kev nco qab tsis meej pem los yog tsis tag, qhov notxoj kev tsis pub. Hauv qhov no, koj yuav tsum tau tso tus neeg raug tsim txom ntawm nws sab thiab tos cov kws kho mob tuaj txog.

Tom qab analgin lom, kev kho mob yog qhia
Tom qab analgin lom, kev kho mob yog qhia

Kev kho mob

Nws yog ua tiav hauv qhov chaw nyob ruaj khov. Kev kho mob suav nrog cov txheej txheem hauv qab no:

  • YForced diuresis. Tus neeg mob tau txhaj rau hauv cov ntshav nrog 4-5 litres ntawm cov ntshav hloov pauv, vim tias qhov ntim ntawm cov ntshav nce ntxiv. Lub raum pib nquag tshem cov tshuaj lom hauv lub cev.
  • Ua kom tshem tawm cov co toxins los ntawm cov quav stimulation. Ib tug neeg tau muab tshuaj laxative los yog tshuaj enteric yog txhaj rau hauv lub plab kom yaug cov hnyuv.
  • Kho nrog adsorbents. Siv activated charcoal los yog sodium hypochlorite.
  • Hemodialysis. Tus neeg mob cov ntshav nyob rau hauv cov tshuaj lom hnyav yog lim los ntawm ib tug semi-permeable membrane.

Yog tias noj tshuaj ntau dhau, tej zaum yuav xav tau resuscitation. Lawv tau ua thaum tsis nco qab, convulsive syndrome, urinary thiab circulatory disorders thiab psychosomatic ntshawv siab.

Yog tus neeg noj 5-8 gram ntawm cov tshuaj, thiab nws tsis tau txais kev pab raws sijhawm, nws yuav tuag.

Pom zoo: