Puas yog tso cai ua ke cawv thiab "Betaserc"? Cia peb sim ua kom tiav. Betaserc yog ib qho tshuaj kho mob. Nws muaj ib daim ntawv ntau npaum - ntsiav tshuaj. Txhua tus neeg uas tau sau ntawv "Betaserk" yuav tsum tau txais cov ntaub ntawv ntxiv txog cov tshuaj no. Ua ntej, nws tsis paub meej tias nws puas tuaj yeem ua ke cov tshuaj nrog cawv thiab seb puas yuav muaj qhov tshwm sim loj. Qhov thib ob, nws yog ib qho tseem ceeb kom paub meej txog cov yam ntxwv ntawm kev siv "Betaserk", qhov tshwm sim tshwm sim. Tag nrho cov ntaub ntawv no tso cai rau koj noj tshuaj kom raug yam tsis muaj kev phom sij rau koj lub cev.
Rau qhov sib xyaw ntawm Betaserc thiab cawv
Yuav luag thaum noj tshuaj, tib neeg xav tias nws tuaj yeem ua ke nrog cawv. Ib qho xwm txheej tshwm sim yog tias ib ntsiav tshuaj ntawm cov tshuaj tau noj, thiabHais lus nyob rau hauv ib teev, ib tog yuav pib ntawm cov phooj ywg hauv tsev, thiab cov dej qab zib uas muaj cawv yuav nyob ntawm lub rooj. Yuav ua li cas: tsis kam lossis haus me ntsis? Kuv puas tuaj yeem noj Betaserc nrog cawv?
Tshwj xeeb, cov lus qhia tsis muaj dab tsi hais txog qhov tsis sib xws ntawm cov tshuaj nrog ethyl cawv. Qhov no tsis tau txhais hais tias koj tuaj yeem haus cov dej haus uas muaj cawv. Nws tsuas yog tias cov chaw tsim khoom ntawm cov tshuaj tsis tau tshwj xeeb los tshawb fawb txog cov ncauj lus no. Yog, thiab lawv tsis muaj kev nkag siab ntau. Los ntawm thiab loj, nws yog undesirable los muab tag nrho cov tshuaj nrog cawv, thiab Betaserc yog tsis muaj kev zam. Cov tshuaj muaj txiaj ntsig zoo rau kev rov qab los, rov ua haujlwm ntawm qee yam ntawm lub cev. Ethyl cawv muaj qhov sib txawv. Nws ua rau lub hlwb, lub plawv, siab, thiab ua rau lub plab mucosa.
Qhov tshwm sim ntawm kev noj tshuaj thiab cawv
Nws yooj yim twv seb qhov txiaj ntsig yuav tshwm sim los ntawm kev siv "Betaserc" ib txhij thiab cov dej qab zib uas muaj cawv. Cawv tuaj yeem ua rau mob taub hau, kiv taub hau. Tus neeg qaug cawv poob kev taw qhia hauv lub sijhawm thiab qhov chaw, tsim kev hais lus tsis zoo, taug kev tsis sib xws, staggers.
Thiab tam sim no cia peb saib xyuas cov tshuaj ua haujlwm ntawm cov tshuaj "Betaserc". Cov tshuaj txhim kho microcirculation. Nws raug nquahu kom coj nws mus rau cov neeg uas raug mob kiv taub hau, yws ntawm tinnitus, mob taub hau. Yog tias ib tus neeg muaj cov tsos mob zoo li no haus cawv, nws tsuas yog ua rau nws txoj kev noj qab haus huv tsis zoo. Cov tshuaj vim muaj ethyl cawv hauv lub cev tsis yogtuaj yeem ua tau zoo. Qee tus neeg hauv kev tshuaj xyuas tau lees paub qhov no, hais txog kev mob taub hau, tinnitus thiab ntau dua.
Cov khoom lag luam dav dav
Yog li, cov lus teb rau cov lus nug nquag nug txog kev siv ib txhij ntawm "Betaserk" thiab cawv tau muab. Tam sim no cia peb mus ncaj qha rau kev txiav txim siab ntawm cov tshuaj. Cia peb pib nrog qhov tseeb tias Betaserc yog cov tshuaj paub thoob plaws ntiaj teb. Nws tau muaj nyob rau yuav luag 50 xyoo. Thaum lub sij hawm tag nrho cov sij hawm no, cov tshuaj tau thiab tseem yog ib tug ncaj ncees pab rau neurologists thiab cov neeg mob.
Betaserc yog thawj zaug sau npe hauv Tebchaws Europe hauv xyoo 1970. Nyob rau tib lub sijhawm, cov kws tshaj lij tau txiav txim siab kom muaj kev nyab xeeb thiab tseem siv tau zoo rau tib neeg. Cov kev tshawb fawb ntxiv ntawm cov tshuaj tau pom tias Betaserk tsis cuam tshuam rau kev ua haujlwm ntawm lub hlwb, tsis muaj cov nyhuv sedative, thiab tsis ua rau qaug zog. Tsis tas li ntawd, cov tshuaj tsis cuam tshuam rau cov ntshav siab, uas tseem ceeb heev rau cov neeg mob ntshav siab.
Kev sib sau thiab tso tawm daim ntawv
"Betaserc" yog tsim los ntawm betahistine dihydrochloride. Cov tshuaj no yog lub active ingredient nyob rau hauv cov tshuaj. Betahistine dihydrochloride yog cov tshuaj histamine analogue. Nws yog thawj synthesized nyob rau hauv 1941. Txawm li cas los xij, cov tshuaj no tsis tau tam sim ntawd nyiam cov kws kho mob tshwj xeeb. Tsuas yog nyob rau hauv thaum ntxov 60s ntawm lub xyoo pua xeem, kev tshawb fawb ntawm betahistine dihydrochloride pib, thiab ib tug me ntsis tom qab, nyob rau hauv lub hauv paus ntawm no histamine analogue, cov tshuaj nyob rau hauv nqe lus nug pib tsim.
Betaserc kuj muaj cov khoom ntxiv:
- Ymicrocrystalline cellulose;
- mannitol (E421);
- talc;
- colloidal silicon dioxide;
- Ycitric acid monohydrate.
Cov tshuaj yog tsim, raws li tau hais los saum toj no, nyob rau hauv daim ntawv ntawm cov ntsiav tshuaj. Lawv yog cov puag ncig, biconvex, dawb los yog yuav luag dawb. Cov ntsiav tshuaj tau muab tso rau hauv cov hlwv thiab hauv cov pob ntawv cardboard nrog rau cov lus qhia siv. Pob ntawv nrog ntau tus naj npawb ntawm cov ntsiav tshuaj yog muag - 20, 30 thiab 60 daim. Nws tseem tsim nyog ua tib zoo saib xyuas qhov tseeb tias cov ntsiav tshuaj muaj nyob rau hauv ntau npaum li cas - 8, 16 thiab 24 mg txhua.
Vim li cas Betaserk tau sau
Cov kws tshaj lij tab tom sau cov tshuaj tshawb fawb rau cov neeg mob kuaj mob Meniere's syndrome. Qhov no yog ib yam kab mob tsawg tsawg. Raws li kev txheeb cais, nws tau kuaj pom hauv 20-200 tus neeg ntawm 100 txhiab tus neeg. Hauv cov tshuaj, Meniere's syndrome tau nkag siab tias yog kab mob uas tsis yog-purulent ntawm pob ntseg. Nrog rau kev mob, qhov ntim ntawm cov kua labyrinth nce, qhov siab ntawm lub labyrinth nce. Hauv cov neeg mob, qhov no ua rau muaj kev cuam tshuam ntawm kev lag ntseg, tinnitus, kiv taub hau, thiab tsis txaus ntseeg. Ib qho ntawm qhov ua tau ntawm kev txhim kho ntawm Meniere's syndrome muaj xws li teeb meem nrog cov hlab ntsha, qhov tshwm sim ntawm kev raug mob ntawm pob ntseg, taub hau.
Nyob rau hauv cov lus qhia txuas nrog "Betaserk", lwm qhov qhia tau hais tias - kev kho mob ntawm vestibular vertigo (vertigo).
Yuav ua li cas rau cov khoom siv hauv lub cev
Betahistine hauvgastrointestinal ib ntsuj av yog sai heev thiab yuav luag tag absorbed. Tsis tas li ntawd, cov khoom no yog metabolized. Thaum lub sijhawm txheej txheem no, kev tsim cov metabolite ntawm 2-pyridylacetic acid tshwm sim (tsis muaj cov tshuaj pharmacological).
Ib teev tom qab noj "Betaserc" hauv cov neeg mob hauv cov ntshav plasma, qib 2-pyridylacetic acid nce mus rau qhov siab tshaj plaws. Ib nrab-lub neej yog kwv yees li 3.5 teev. Raws li cov kws tshaj lij, 2-pyridylacetic acid tau tawm hauv lub cev nrog cov zis.
Cov txheej txheem tib yam, tsis muaj kev hloov pauv loj, tshwm sim thaum Betaserc thiab cawv nkag mus rau hauv lub cev.
Lub luag haujlwm ntawm kev ua ntawm cov tshuaj nquag
Cov nyhuv ntawm betahistine tseem tsis tau nkag siab. Cov ntaub ntawv muaj qhia tau hais tias cov tshuaj no khi rau H 1receptors embedded nyob rau hauv lub neuroreceptor hlwb ntawm lub pob ntseg. Betahistine muaj cov nyhuv stimulating hauv zos. Yog li ntawd, kev tso tawm ntawm cov neurotransmitters (histamine) mus rau hauv lub synapse los ntawm cov hlab ntsha xaus ntawm lub receptor hlwb ntawm lub pob ntseg puab nce. Nyob rau hauv lem, neurotransmitters ua rau precapillary sphincters. Qhov tshwm sim ntawm qhov kev cuam tshuam no yog vasodilation ntawm cov hlab ntsha ntawm pob ntseg, nce hauv lawv cov permeability, thiab normalization ntawm intralabyrinthine siab.
Betahistine kuj ua rau cov receptors ntawm lub vestibular nuclei, uas nyob rau hauv lub medulla oblongata. Raws li kev cuam tshuam ntawm cov tshuaj nquag Betaserk, qib ntawm serotonin hauv medulla oblongata nce. Tsis tas li ntawd, kev ua haujlwm ntawm vestibular nuclei txo qis, lawv excitability txo. Thaum kawgIb tug neeg tau tshem ntawm cov tsos mob tsis zoo li kiv taub hau.
Research results
Ua ntej xav txog cov lus qhia rau kev siv "Betaserk", nqi, analogues thiab kev tshuaj xyuas ntawm cov kws kho mob tshwj xeeb txog cov tshuaj no, cia peb ua tib zoo saib xyuas qhov tseeb tias ntau qhov kev sim tau ua yav dhau los. Lawv lub hom phiaj yog los ua pov thawj qhov ua tau zoo ntawm cov tshuaj thiab nws cov superiority tshaj lwm yam tshuaj. Piv txwv li, ib txoj kev tshawb fawb muaj xws li cinnarizine. "Betaserc" thiab cinnarizine tau muab rau cov neeg yws ntawm kiv taub hau. Tom qab ib hlis ntawm kev kho mob, cov kws kho mob tshwj xeeb tau sau thawj qhov txiaj ntsig tseem ceeb - cov neeg mob tsis muaj kiv taub hau. Qhov no tau ua pov thawj tias Betaserc thiab cinnarizine yog cov tshuaj zoo.
Txawm li cas los xij, qhov kev sim ua tsis tiav. Nws kuj tau npaj los ntsuas qhov kev ua haujlwm vestibular hauv 2 pawg ntawm cov neeg mob - cov neeg uas tau noj Betaserc thiab cov neeg uas noj cinnarizine. Cov txiaj ntsig hauv txhua pab pawg sib txawv. Tawm tsam keeb kwm yav dhau los ntawm kev siv "Betaserk", muaj qhov nyiam ntawm vestibular muaj nuj nqi rau symmetrical hyporeflexia. Qhov no yog qhov lav tias cov neeg mob yuav tsis raug tsim txom los ntawm kev mob kiv taub hau. Kev siv cinnarizine tsis tau txhim kho vestibular muaj nuj nqi. Tsuas yog cov tsos mob tau kaw. Tom qab nres cinnarizine, tib neeg muaj kiv taub hau dua tom qab ib ntus.
Contraindications rau kev siv
Raws li kws kho mob tshuaj xyuas, "Betaserc" tsis pom zoo siv thaum muaj kev kub siab rau ib qho twg.tshuaj los ntawm cov muaj pes tsawg leeg ntawm cov tshuaj los yog mus rau ntau yam. Lwm cov tshuaj tsis raug sau tseg rau pheochromocytoma. Nws yog ib qho benign, hormonally active qog uas feem ntau tsim los ntawm chromaffin hlwb ntawm adrenal medulla.
Tsis muaj kev tshawb fawb los txiav txim siab qhov ua tau zoo thiab kev nyab xeeb ntawm Betaserc hauv cov neeg mob xws li menyuam yaus, cev xeeb tub thiab lactating poj niam. Vim li no, cov tshuaj tsis raug sau tseg txog thaum muaj hnub nyoog 18 xyoo. Cov poj niam cev xeeb tub tuaj yeem siv cov tshuaj tsuas yog thaum muaj qhov xav tau pom tseeb. Nyob rau hauv txoj hauj lwm, nws tau pom zoo kom tsis txhob muab cawv thiab Betaserk. Cov txiaj ntsig tsis zoo, vim nws paub tias ethyl cawv ua rau tus menyuam hauv plab, ua rau muaj kev cuam tshuam hauv nws txoj kev loj hlob. Tsis tas li ntawd, betahistine tuaj yeem cuam tshuam rau tus menyuam hauv plab. Rau cov poj niam cev xeeb tub, cov tshuaj tau muab tshuaj tom qab ntsuas qhov muaj feem cuam tshuam rau tus menyuam mos.
Txoj kev tswj hwm thiab noj ntau npaum li cas
Noj "Betaserk" nrog zaub mov. Qhov koob tshuaj txhua hnub rau cov neeg laus yog 48 mg. Qee zaum, nws yuav tsawg dua. Cov koob tshuaj raug xaiv los ntawm tus kws kho mob uas tuaj koom rau txhua kis tshwj xeeb. Thaum muab tshuaj rau cov neeg laus, nws tsis raug kho. Tsis tas li ntawd, tsis tas yuav hloov koob tshuaj rau cov neeg mob siab lossis lub raum tsis txaus.
Yuav faib cov koob tshuaj li cas txhua hnub? Ua ntej tshaj plaws, koj yuav tsum tau them sai sai rau qhov ntau npaum ntawm cov ntsiav tshuaj. "Betaserk" 24 mg yog qaug dej qaug cawv 2 zaug hauv ib hnub, 1 ntsiav tshuaj. Hauv cov xwm txheej hnyav, cov kws kho mob nce thawj koob tshuaj ntawm 24 txog 48 mg. Tab sis qhov kev txiav txim yog uatsuas yog tus kws tshaj lij! Hauv cov koob tshuaj me me, Betaserc tau muab tshuaj rau kev kho mob ntawm lub cev tsis muaj zog (8 lossis 16 mg 2 zaug hauv ib hnub).
Nws tso cai rau cov ntsiav tshuaj ua 2 halves ua ntej noj, tab sis qhov no yuav tsum tau ua tsuas yog kom cov tshuaj tau nqos tau yooj yim dua. Nws tsis tuaj yeem faib cov ntsiav tshuaj txhawm rau txhawm rau noj ib nrab tom qab. Qhov khoom yog tias nyob rau hauv daim ntawv no ntau npaum, thaum lub sij hawm tsim khoom, cov khoom xyaw nquag tsis tuaj yeem muab faib sib npaug.
Raws li cov lus teb los ntawm cov neeg mob, thaum noj tshuaj, kev txhim kho pib pom tom qab ob peb lub lis piam. Yuav tsum tau kho ob peb lub hlis kom tau txais txiaj ntsig zoo.
Qee pawg neeg mob yuav tsum tau ceev faj thaum siv Betaserc. Cov no suav nrog cov neeg mob plab thiab / lossis duodenal ulcers, bronchial hawb pob.
Cov kev mob tshwm sim thiab cov tsos mob ntawm kev noj tshuaj ntau dhau
Cov neeg mob noj Betaserc tej zaum yuav ua rau xeev siab, dyspepsia. Cov tsos mob no suav hais tias yog ib txwm muaj. Tseem muaj cov ntaub ntawv ntxiv hauv cov ntaub ntawv kho mob hais txog qhov tshwm sim tsis zoo, txawm li cas los xij, qhov zaus ntawm lawv qhov tshwm sim niaj hnub no tsis tuaj yeem txiav txim siab, vim tias tsis muaj cov ntaub ntawv txaus rau kev tshuaj xyuas. Cov npe ntawm cov "kev mob tshwm sim" suav nrog cov tshuaj tiv thaiv tsis haum (pob liab, khaus khaus, urticaria, angioedema, anaphylactic cov tshuaj tiv thaiv), ntuav, tsam plab.
Lwm cov tsos mob tau pom nyob rau hauv kev noj tshuaj ntau dhau. Nws tshwm sim vim kev txhob txwm tshaj tawm ntawm cov koob tshuaj ntau. Cov kws kho mob tshwj xeeb tau ntsib cov tsos mob uas tshwm sim vimkoob tshuaj mus txog 640 mg. Cov neeg mob tau pw tsaug zog, xeev siab, thiab mob plab. Ntau cov tsos mob hnyav dua tau pom nrog cov koob tshuaj ntau dua ua ke nrog overdose los ntawm lwm cov tshuaj. Hauv kev xyaum, muaj cov mob convulsions, cardiopulmonary teeb meem.
Cov tsos mob tsis zoo tau pom thaum haus cawv thiab Betaserc ua ke. Ua rau lawv ethyl cawv. Cov neeg mob hnyav dua, lawv lub taub hau mob, thiab lwm yam. Nws tsis paub txog cov tsos mob tshwj xeeb uas tshwm sim los ntawm kev sib cuam tshuam ntawm Betaserc nrog cawv.
Nqe thiab analogues
Tus nqi ntawm "Betaserk" nyob ntawm tus naj npawb ntawm cov ntsiav tshuaj thiab ntau npaum li cas:
- pob nrog 30 ntsiav tshuaj ntawm 8 mg tus nqi nruab nrab ntawm 420 rubles;
- ib pob ntawm 30 ntsiav tshuaj ntawm 16 mg nqi txog 600 rubles;
- ib pob ntawm 20 ntsiav tshuaj ntawm 24 mg tuaj yeem yuav tau rau 530 rubles;
- pob nrog 60 ntsiav tshuaj ntawm 24 mg nqi kwv yees li 1200 rubles.
Ua tiav analogues ntawm "Betaserk" yog "Betaver", "Betahistine". Tag nrho cov tshuaj no yog tsim los ntawm tib yam active tshuaj. Vim li no, cov lus qhia rau kev siv yog tib yam. Qhov sib txawv ntawm cov tshuaj yog nyob rau hauv tus nqi. Piv txwv li, Betahistine, tsim los ntawm Ozon LLC, raug nqi txog 50 rubles rau ib pob ntawm 8 mg ntsiav tshuaj. Cov tshuaj tib yam, tab sis tsim los ntawm lwm lub chaw tsim khoom (LLC Pranapharm), tus nqi kwv yees li 70 rubles rau ib pob ntawm 30 ntsiav tshuaj ntawm 24 mg txhua.
Kev sib tham nrog lwm yam tshuaj
txhawm rau kawm txog kev cuam tshuam ntawm "Betaserk" nrog lwm tustshuaj, kev sim tshwj xeeb ntawm cov tsiaj thiab tib neeg tsis tau ua tiav. Tsuas yog cov kev tshawb fawb hauv vitro tau ua tiav. Hauv ib qho ntawm cov txiaj ntsig, inhibition ntawm cov metabolism ntawm Betahistine dihydrochloride los ntawm cov tshuaj uas inhibit monoamine oxidase (MAO) tau tshwm sim. Qhov kev tshawb pom no ua rau muaj kev pom zoo tias yuav tsum tau ceev faj thaum sau tshuaj Betaserc thiab MAO inhibitors.
Tseem muaj qhov kev xav txog kev xav txog kev cuam tshuam ntawm Betaserc ntawm kev ua haujlwm ntawm cov tshuaj uas yog blockers ntawm H1-histamine receptors. Qhov tshaj plaws yog tias Betahistine yog suav tias yog ib feem agonist ntawm H 1-histamine receptors, uas yog, nws nce cov lus teb ntawm receptors.
Yog li, peb tau tshuaj xyuas cov lus qhia rau kev siv "Betaserk", nqi, analogues. Kev tshuaj xyuas txog cov tshuaj no zoo heev. Txhua tus kws kho mob neurologist paub nws. Cov kws tshaj lij hais tias "Betaserk" zoo tshem tawm cov teeb meem ntawm lub vestibular thiab cochlear apparatus, txo qhov kev siv thiab zaus ntawm kiv taub hau, txo qis tinnitus, thiab txhim kho kev hnov lus tsis zoo. Ua tsaug rau cov tshuaj no, tau txais txiaj ntsig zoo hauv kev kho mob me me lossis tsis muaj kev phiv.
