Nyob rau hauv tsab xov xwm, peb yuav txiav txim siab cov lus qhia rau kev siv, nqi, tshuaj xyuas thiab analogues rau cov tshuaj "Reserpine".
Nws yog ib qho tshuaj sympatholytic complex uas muaj antihypertensive, antipsychotic thiab sedative teebmeem. Cov tshuaj nquag ntawm cov tshuaj no yog ib qho ntawm cov alkaloids ntawm cov nroj tsuag tsis tshua muaj xws li nab rauwolfia.
YPharmacokinetics
Cov tshuaj "Reserpine" yog ib qho tshuaj antispasmodic uas feem ntau cuam tshuam rau lub paj hlwb, qhov txo qis uas tso cai rau koj los ua kom cov parasympathetic. Nws muaj cov txiaj ntsig them nyiaj.
Cov tshuaj no tuaj yeem ua rau cov ntshav siab tsis tu ncua. Qhov no yog qhia los ntawm cov lus qhia rau kev siv. Ntawm qhov siab npaum li cas nws tso cai rau sau "Reserpine" yog qhov txaus siab rau ntau tus. Nws muaj txiaj ntsig zoo.
Cov tshuaj tiv thaiv kev puas siab puas ntsws yog ua raws li kev txo qis ntawm qee yam neurotransmitters hauv cov neurons, cov no suav nrog serotonin thiab dopamine. ATCov tshuaj muaj xws li cov tshuaj nquag - reserpine, hydrochlorothiazide, dihydralazine sulfate.
"Reserpine" ua cov tshuaj kho mob hauv qab no rau tib neeg lub cev:
- kev nyuaj siab plawv;
- txo tag nrho peripheral vascular resistance;
- deepens thiab txhim kho lub cev pw tsaug zog;
- slows down metabolism hauv cov neeg mob ntshav siab thiab coronary atherosclerosis;
- ntxiv dag zog rau kev cuam tshuam ntawm cov tshuaj xws li tshuaj tsaug zog thiab tshuaj kho mob;
- stabilizes metabolism ntawm cov rog thiab cov protein;
- ua pa tsis zoo, nws dhau los ua tsawg dua thiab tob dua;
- menyuam kawm ntawv constricts, kub poob;
- ua kom cov tshuaj hydrochloric acid los ntawm lub plab;
- plab hnyuv peristalsis nce;
- ntshav rau lub raum txhim kho;
- lub raum glomerular pom nce.
Dab tsi ntxiv phau ntawv qhia rau Reserpine qhia rau peb?
Cov tshuaj kuj muaj txiaj ntsig zoo, txij li thawj cov txiaj ntsig tau pom tom qab ob peb hnub ntawm kev siv, qhov siab tshaj plaws tau ua tiav tom qab 2-6 lub lis piam yog tias noj tsis tu ncua.
Lub sijhawm kom tshem tawm cov tshuaj tawm hauv lub cev kom tiav yog kwv yees li 4-6 lub lis piam.
Dab tsi yog qhov qhia rau Reserpine raws li cov lus qhia rau kev siv?
Kev qhia
"Reserpine" yog siv rau cov kab mob hauv qab no:
- mob hlwb ntawm vascular keeb kwm;
- mob ntshav siab, thaum muaj ntshav siab nce ntxiv;
- psychosis uas tshwm sim nrog ntshav siab;
- neuroses;
- mob ntshav siab;
- Ythyrotoxicosis;
- manic arousal hauv cycloid psychosis;
- psychomotor agitation hauv cov neeg mob schizophrenia.
Muaj peev xwm contraindications
Raws li cov lus qhia rau kev siv, "Reserpine" yuav tsis siv los ntawm txhua tus neeg mob uas xav tau nws, yog li koj yuav tsum tsis txhob siv thaum:
- peptic rwj ntawm duodenum thiab plab;
- kev nyuaj siab;
- bronchial hawb pob;
- mob hnyav ntawm lub plawv thiab cov hlab ntsha;
- bradycardia;
- nephrosclerosis;
- Parkinson's disease;
- cerebrovascular atherosclerosis;
- tshuaj kho nrog hluav taws xob impulses;
- hypersensitivity rau cov khoom ntawm cov tshuaj no;
- tsis ua pa;
- kab mob gallstone;
- pheochromocytoma;
- angle-kaw glaucoma;
- mob plawv tsis ua hauj lwm;
- pub mis niam thiab cev xeeb tub.
Side tsos mob
Tus nqi thiab tshuaj xyuas rau "Reserpine" yuav nthuav tawm hauv qab no.
Cov lus qhia rau kev siv qhia tias thaum siv tshuaj, cov tsos mob tsis xav tau kuj tshwm sim:
- digestive system: cov neeg mobNco ntsoov qhov mob hauv thaj tsam epigastric, cov tsos mob ntawm dyspepsia, qhov kev xav ntawm qhov ncauj qhuav, muaj zog poob qab los noj mov, los ntshav los ntawm txoj hnyuv thiab plab tsis tshua pom;
- nervous system: mob taub hau, pw tsaug zog cuam tshuam, tus neeg mob ntxhov siab, nkees nkees, txo libido, hyporeflexia;
- cov hlab ntsha thiab lub plawv: muaj arrhythmia, bradycardia thiab mob hauv qhov chaw tom qab lub sternum;
- urinary system: teb rau cov tshuaj Reserpine nrog ntsev thiab dej metabolism, tshwm sim hauv dryness thiab peripheral edema ntawm mucous daim nyias nyias, ntxiv rau, dysuria thiab anuria yuav tshwm sim;
- epidermal integument: urticaria, pruritus, exacerbation ntawm herpetic kab mob;
- Tam sim muaj mob siab ua haujlwm thiab tib neeg qhov hnyav nce.
Cov lus qhia rau kev siv "Reserpine"
Cov tshuaj tau noj tom qab noj mov thiab ntxuav nrog dej lossis cov kua dej hauv qhov ntim txaus. Raws li cov lus qhia, cov tshuaj tau muab rau kev kho mob ntawm thawj theem ntawm kev kub siab ntawm qhov ntau npaum ntawm 0.1 mg ob zaug ib hnub. Lub sijhawm ntawm nws siv yog kwv yees li xya hnub. Thaum tsis muaj kev kho mob thaum lub sijhawm no, nws raug nquahu kom nce koob tshuaj rau 0.5 mg, kuj muab faib ua ob koob.
Yog tias tus neeg mob tau ua tiav thiab cov ntshav siab tau mus txog qhov xav tau, cov koob tshuaj maj mam txo mus rau 0.1 mg. Tshuaj kho mobcoj tom qab ntawd rau kev kho mob.
Kev kho mob tag nrho yuav kav li ob mus rau plaub lub hlis.
Tsis tas li, cov tshuaj tuaj yeem raug sau rau kev kho mob nyuaj rau lwm yam kev qhia (tachycardia, thyrotoxicosis, lig preeclampsia) thiab siv nrog rau lwm yam tshuaj. Nyob rau hauv tas li ntawd, nws raug muab nruj me ntsis rau tus kheej.
Ntau tshaj
Raws li cov lus qhia rau kev siv rau cov ntsiav tshuaj Reserpine, thaum lawv siv nrog ntau npaum li cas, cov tsos mob xws li:
- sudden ntshav siab;
- mob plab;
- bradycardia;
- npau suav phem;
- parkinsonism;
- coma;
- ntua;
- hypothermia;
- tremor;
- mob siab.
Kev kho rau cov tsos mob zoo li no yog cov tsos mob, nws muaj nyob rau hauv kev qhia txog cov tshuaj intravenous. Hauv cov xwm txheej tshwj xeeb, kev txhaj tshuaj ntawm cov tshuaj amines yog xav tau.
Kev cuam tshuam tshuaj yeeb tshuaj
Cov lus qhia rau kev siv rau "Reserpine" kuj tau tshaj tawm tias nrog kev siv cov tshuaj sib npaug thiab lwm yam tshuaj, tus kws tshaj lij saib xyuas ib txwm xav tau, vim tias cov tshuaj no tuaj yeem cuam tshuam nrog ntau yam tshuaj, ua rau tsis muaj zog lossis txhim kho lawv cov txiaj ntsig kho. Cia peb piav qhia txog qhov kev sib cuam tshuam no kom ntxaws ntxiv.
- Foxglove cov kev kho mob ua rau muaj kev pheej hmoo ntawm bradycardia.
- Sib koom nrog ethanol,barbiturates, tricyclic antidepressants, inhalation anesthesia tshuaj txhim kho lawv cov nyhuv.
- "Reserpine" tuaj yeem txo cov txiaj ntsig ntawm cov tshuaj tiv thaiv kab mob thiab cov tshuaj anticholinergics, nrog rau txo cov nyhuv analgesic ntawm morphine.
- "Reserpine" pab txhawb rau qhov ntev ntawm cov tshuaj adrenomimetic ncaj qha.
- Thaum muab tshuaj rau qhov muag, qhov nce ntshav siab tau sau tseg.
- Thaum siv tricyclic antidepressants, cov nyhuv hypotensive ntawm "Reserpine" txo qis.
- Cov tshuaj "Fenfluramine" txhim kho cov nyhuv hypotensive ntawm cov tshuaj, thiab "Methyldopa" txhim kho lub xeev kev nyuaj siab.
Tus nqi
Tus nqi ntawm cov tshuaj yog los ntawm 380-420 rubles. Nws nyob ntawm cov khw muag tshuaj thiab cheeb tsam.
Analogues
Reserpine muaj xws li cov analogues xws li Christoserpin, Eskaserp, Rausedil, Raupazil, Alserin, Raused Serfin, Tenserpin, Questsin, Rausedan, "Serpin", "Roxinoid", "Serpiloid", "Sedaraupin", "Tenserpin", " Serpat".
Reviews
Cov tshuaj Reserpine tau sau cov kev tshuaj xyuas sib xyaw los ntawm tib neeg: qee tus neeg mob ntseeg tias nws muaj txiaj ntsig zoo, lwm tus nco ntsoov tias muaj ntau cov tsos mob tshwm sim tsis zoo tshwm sim.
Qee cov neeg mob ntshav siab, noj "Reserpine" es tsis txhob siv lawv li ib txwm, pom tias nws qhov kev ua tau zoo rov qab los zoo li qub, lub paj hlwb tau pom tsawg dua. Ntxiv mus, cov tshuajtau noj thawj zaug hauv qhov tsawg kawg nkaus, thiab tom qab ntawd nws tau nce ntxiv raws li cov txheej txheem tsim los ntawm tus kws kho mob. Kev hloov pauv zoo tau pom tom qab ob lub hlis.
Lwm tus nco ntsoov tias Reserpine pab ua kom ntshav siab, tab sis tom qab ob hnub mob taub hau ntev pib tshwm, uas ploj lawm tsuas yog nyob rau lub lim tiam thib tsib ntawm kev kho mob nrog cov tshuaj no.
Peb tau tshuaj xyuas cov lus qhia siv rau Reserpine, nqe, tshuaj xyuas thiab analogues.