Ntshav yog ib yam mob uas tuaj yeem ua rau tib neeg lub neej. Txhawm rau tshem tawm lawv, kev npaj hemostatic tau tsim. Cov npe ntawm cov tshuaj no suav nrog Dicinon. Qhov no yog ib qho tshuaj noj thiab yuav tsum tsis txhob siv ntawm koj tus kheej. Wb paub txog cov lus qhia thiab kev phiv ntawm Dicinon.
Cov ntawv noj tshuaj thiab muaj pes tsawg leeg
Hauv khw muag tshuaj, Dicinon muaj nyob rau hauv 2 daim ntawv:
- yog tshuaj txhaj rau cov leeg thiab leeg;
- hauv daim ntawv ntsiav tshuaj rau kev siv sab hauv.
Ob daim ntawv noj tshuaj yog raws li etamsylate. Qhov no yog cov khoom xyaw nquag hauv Dicinone, uas muaj cov nyhuv hemostatic. Nyob rau hauv tib neeg lub cev, etamsylate ua rau ib txwm capillary permeability, muaj ib tug stimulating nyhuv ntawm tsim platelets, pab nres los ntshav, txo los ntshav.
Tsis tas li, cov khoom xyaw ntawm "Dicinon" muaj cov khoom siv pabcuam. Cov tshuaj suav nrog sodium disulfite, sodium bicarbonate, dej rau kev txhaj tshuaj. Cov excipients nyob rau hauv cov ntsiav tshuaj yog pob kws starch, lactose, anhydrous citric acid, povidone thiab magnesium stearate.
Ua ntej siv cov tshuaj, nws yuav tsum tau coj mus rau hauv tus account nws cov muaj pes tsawg leeg, vim hais tias cov kev phiv ntawm Dicinon tshwm sim vim nws cov khoom. Tus neeg mob uas paub txog qhov muaj qhov tsis haum rau ib qho ntawm cov tshuaj saum toj no yuav tsum qhia rau tus kws kho mob.
Pharmacodynamics thiab pharmacokinetics
Etamsylate, uas yog cov khoom xyaw nquag hauv Dicinone, tsis tsuas yog cuam tshuam rau cov hlab ntsha thiab cov platelet tsim. Nws txo cov synthesis ntawm prostaglandins. Los ntawm txoj kev, vim lawv, platelet disaggregation tshwm sim hauv lub cev, lumen ntawm cov hlab ntsha thiab capillary permeability nce.
Cov tshuaj nquag ntawm cov tshuaj yuav luag tsis cuam tshuam rau cov ntshav peripheral, nws lipoproteins thiab cov proteins. Nws tsuas tuaj yeem txo qhov erythrocyte sedimentation tus nqi. Tsis tas li ntawd, etamsylate tsis ua rau vasoconstriction.
Pharmacokinetics nyob ntawm daim ntawv ntau npaum. Thaum cov tshuaj tau muab tso rau hauv cov hlab ntsha, cov nyhuv hemostatic ntawm cov tshuaj pib tshwm sim tom qab li 5 feeb. Cov nyhuv siab tshaj plaws tshwm sim 1-2 teev tom qab kev qhia txog kev daws teeb meem thiab kav li 4 mus rau 6 teev. Tom qab ntawd cov nyhuv maj mam tsis muaj zog thaum nruab hnub. Thaum cov tshuaj txhaj rau hauv cov leeg, cov nyhuv hemostatic pib hauv 30-60 feeb. Tom qab noj cov ntsiav tshuaj ntau npaum li cas, nws yuav siv sijhawm rau cov tshuaj kom yaj hauv plab, nkag muslos ntawm cov mucous daim nyias nyias mus rau hauv cov hlab ntsha thiab kis mus thoob plaws lub cev.
Cov tshuaj nquag "Dicinon" yog me ntsis metabolized hauv lub cev. Ib tug loj feem ntawm cov tshuaj (kwv yees li 80% ntawm cov tshuaj siv) yog excreted unchanged los ntawm ob lub raum. Thiab ntawm no cov lus nug tshwm sim: Puas yog Dicinon provoke cov kev mob tshwm sim hauv cov neeg uas muaj lub siab tsis zoo thiab lub raum ua haujlwm? Nws tsis tuaj yeem muab cov lus teb tsis tseeb ntawm no, vim tsis muaj cov txiaj ntsig ntawm cov kev tshawb fawb cuam tshuam.
Indications thiab contraindications
Qee qhov qhia tau muaj rau cov tshuaj thiab cov ntsiav tshuaj:
- kev ua haujlwm (cov ntsiav tshuaj siv ua ntej thiab tom qab lawv);
- hematuria - muaj ntshav hauv cov zis (deviation los ntawm tus qauv);
- metrorrhagia - qhov tsos ntawm uterine los ntshav tsis cuam tshuam nrog kev coj khaub ncaws;
- menorrhagia hauv cov poj niam uas siv cov tshuaj tiv thaiv kab mob hauv lub tsev menyuam, thawj menorrhagia yog kev ua txhaum ntawm kev coj khaub ncaws, tshwm sim los ntawm kev los ntshav ntau thiab ntev;
- cov pos hniav;
- nosebleeds.
Cov tshuaj kuj tuaj yeem muab tshuaj rau ntuav ntshav, cov quav dub ib nrab, uas hauv cov tshuaj hu ua melena. Cov lus qhia ntxiv rau kev qhia txog kev daws teeb meem yog intracranial hemorrhages uas tshwm sim hauv cov menyuam yug tshiab thiab cov menyuam mos ntxov ntxov, mob ntshav qab zib microangiopathy.
Txhawm rau kom tsis txhob ntsib cov kev mob tshwm sim ntawm Dicinon, koj yuav tsum siv cov tshuaj tsis yog tsuas yog muaj cov lus qhia, tab sis kuj yog qhov tsis muaj contraindications. General contraindications rau cov ntsiav tshuaj thiab tshuaj- mob porphyria, hemoblastosis hauv cov menyuam yaus, thrombosis, thromboembolism, hypersensitivity rau cov khoom. Tsis tas li ntawd, cov tshuaj yuav tsum tsis txhob siv rau bronchial hawb pob (nrog rau kev paub tseeb rhiab heev rau sodium sulfite). Ntxiv contraindications rau cov ntsiav tshuaj - lactose intolerance, tsis muaj lactase, malabsorption ntawm qabzib / galactose.
koob tshuaj neeg laus
Rau cov tshuaj, qhov zoo tshaj plaws txhua hnub koob tshuaj yog teem nyob rau hauv 10-20 mg rau 1 kg ntawm lub cev qhov hnyav. Cov tshuaj no feem ntau muab faib ua 3-4 koob. Rau qee qhov xwm txheej, cov koob tshuaj tshwj xeeb tau tsim. Piv txwv li, 1 teev ua ntej kev phais rau kev tiv thaiv, cov kws kho mob txhaj tshuaj 250-500 mg (1-2 ampoules) rau lawv cov neeg mob hauv cov hlab ntsha lossis intramuscularly. Thaum lub sij hawm kev phais, cov koob tshuaj yog rov ua dua. Nws txoj kev tswj hwm yog intravenously. Tom qab kev phais, cov neeg mob tau muab 250-500 mg ntawm cov tshuaj dua txhua 4-6 teev. Tsis txhob siv cov tshuaj tom qab qhov ploj ntawm qhov kev pheej hmoo los ntshav.
Lwm txoj kev thov ntawm cov tshuaj tau tsim los rau kev kuaj mob ntawm "diabetic microangiopathy". Nyob rau hauv lub xub ntiag ntawm xws li ib tug kab mob, Dicinon yog muab tshuaj retrobulbar los yog subconjunctival. Cov koob tshuaj yog ib nrab ntawm ampoule.
Daim ntawv sau tshuaj ntau npaum li cas:
- 1 teev ua ntej kev phais - 1 lossis 2 ntsiav tshuaj;
- tom qab phais - 1 lossis 2 ntsiav tshuaj txhua 4-6 teev;
- kom tsis txhob los ntshav - 2 ntsiav tshuaj txhua 8-12 teev nrog dej lossis zaub mov.
Siv thaum yau
Dicinon tov thiab ntsiav tshuaj tuaj yeem siv thaum yau yog qhia. Cov koob tshuaj pom zoo yog 50% txo tus neeg laus koob. Nws yog ib qho tseem ceeb uas yuav tsum nco ntsoov tias cov ntsiav tshuaj yog contraindicated rau cov menyuam yaus hnub nyoog qis dua 3 xyoos. Txij thaum muaj hnub nyoog 12 xyoos, cov tub ntxhais hluas uas hnyav dua 40 kg tuaj yeem muab tshuaj rau tib koob li cov neeg laus.
Txoj kev daws yog tso cai rau xaiv cov menyuam yug tshiab. Tshwj xeeb rau cov neeg mob pawg no, cov koob tshuaj pom zoo yog 10 mg rau 1 kg ntawm lub cev hnyav. Kev kho mob pib hauv thawj 2 teev tom qab yug me nyuam. Tom qab ntawd kev tswj hwm ntawm cov tshuaj yog rov ua dua txhua 6 teev. Duration ntawm kev kho mob - 4 hnub.
Siv rau kev coj khaub ncaws tsis xwm yeem
Nws twb tau sau tseg saum toj no tias cov tshuaj hemostatic siv tau rau menorrhagia. Rau cov poj niam uas muaj teeb meem no, Dicinon muaj txiaj ntsig zoo. Nws shortens lub sij hawm ntawm kev coj khaub ncaws, i.e. normalizes poj niam muaj nuj nqi. Tsis tas li, cov tshuaj tshem tawm metrorrhagia - los ntshav uas tuaj yeem ua yuam kev rau kev coj khaub ncaws, tab sis qhov tseeb lawv tsis yog.
Hauv kev kho mob metro- thiab menorrhagia, txhua daim ntawv ntau npaum ntawm Dicinon tuaj yeem siv. Cov tshuaj yog muab intravenously los yog intramuscularly. Ib koob tshuaj yog 250 mg. Nws raug tswj hwm txhua 6-8 teev. Lub sijhawm kho yog 5-10 hnub. Kev kho mob nrog cov ntsiav tshuaj yog ua rau tib lub sijhawm. Lawv yuav tsum tau haus 2 daim peb zaug ib hnub twg kom normalize lub cev ntas. "Dicinon" cov kev phiv cuam tshuam nrog kev coj khaub ncaws tsis yogua rau thaum siv kom raug.
Dab tsi yog qhov tseem ceeb rau cov poj niam cev xeeb tub thiab lactating kom paub
Tsis muaj tus kws tshaj lij yuav qhia koj tias qhov tshwm sim, cov teebmeem "Dicinon" thaum cev xeeb tub tuaj yeem ua rau. Tsis muaj cov ntaub ntawv kho mob lees paub qhov kev nyab xeeb ntawm cov tshuaj. Tab sis nws yuav tsum tau borne nyob rau hauv lub siab hais tias ntau yam los ntshav yog ib tug tshwm sim ntawm txaus ntshai teeb meem thiab tej yam kev mob. Lawv xav tau kev kho mob xwm txheej ceev. Vim li no, Dicinon tuaj yeem raug sau tseg. Cov chaw tsim khoom tso cai rau siv tus neeg sawv cev hemostatic nyob rau hauv rooj plaub uas cov txiaj ntsig xav tau tshaj qhov kev pheej hmoo.
Tsis tas li ntawd tsis muaj kev tshawb fawb txog kev nkag mus ntawm cov tshuaj nquag mus rau hauv cov kua mis. Nrog rau cov poj niam cev xeeb tub uas muaj cov lus qhia rau kev siv Dicinon, qhov teeb meem ntawm kev txwv tsis pub pub niam mis rau lub sijhawm kho yuav tsum tau daws.
Side effects
Kev siv cov tshuaj nyob rau hauv daim ntawv ntawm kev daws tsis tas yuav ua rau muaj txiaj ntsig zoo. Feem ntau vim "Dicinon" cov kev mob tshwm sim hauv cov menyuam yaus thiab cov neeg laus. Cov npe ntawm cov teebmeem uas tsis xav tau tshaj plaws suav nrog:
- hnyav hauv thaj tsam epigastric;
- nausea;
- pob khaus;
- mob taub hau;
- kev nyuaj siab.
Tsis tshua muaj tshwm sim yog cov kev mob tshwm sim los ntawm Dicinon, xws li dej ntws tawm ntawm daim tawv nqaij ntawm lub ntsej muag, kiv taub hau, thrombocytopenia, neutropenia, agranulocytosis, arthralgia, kub taub hau, paresthesia ntawm qis extremities, kev tsis haum tshuaj. Kev saib xyuas tshwj xeeb yuav tsum tau them rau qhov kawgtsis xav tau. Kev tsis haum tshuaj tuaj yeem ua rau tsis yog tsuas yog cov tshuaj nquag ntawm cov tshuaj, tab sis kuj tseem muaj cov khoom siv pabcuam. Piv txwv li, sodium sulfite tuaj yeem ua rau xeev siab, raws plab, mob hawb pob, anaphylactic shock, tshwm sim los ntawm kev khaus khaus, ua tsis taus pa, hypoxia, convulsions. Nrog kev phiv, Dcinon raug tso tseg.
Muaj lwm qhov tsis txaus ntseeg. Nrog parenteral kev tswj hwm ntawm cov tshuaj, ntshav siab tuaj yeem txo qis. Qhov no yuav tsum tau coj mus rau hauv tus account thaum kho cov neeg mob los ntawm hypotension.
Kev tshuaj xyuas txog Dicinone, kev phiv tshuaj
Cov kws tshaj lij hais lus zoo txog Dicinone. Raws li lawv, cov tshuaj muaj ntau yam zoo. Ua ntej, nws muaj nyob rau hauv 2 daim ntawv ntau npaum. Qee zaum, nws yog qhov tseeb dua los siv cov tshuaj, thiab lwm tus - ntsiav tshuaj. Qhov thib ob, Dicinon muaj nyob rau hauv txhua lub tsev muag tshuaj thiab pheej yig. Thirdly, nws zoo tiv nrog ntau hom los ntshav. Cov kws kho mob kuj ceeb toom tias cov tshuaj no tsuas yog siv raws li tus kws kho mob tshwj xeeb.
Cov neeg mob kuj feem ntau qhuas cov tshuaj. Hauv lawv cov kev txheeb xyuas, lawv tham txog kev kho kom zoo. Qee tus, nrog kev pab los ntawm Dicinon, rov ua lub cev tsis muaj zog, lwm tus nres qhov ntswg, lwm tus zoo li tsis muaj teeb meem hauv lub sijhawm tom qab phais.
Cov kev xav tsis zoo ntawm tib neegraug tsim, raws li txoj cai, vim hais tias cov tshuaj tsis haum rau lawv. Cov neeg mob hauv kev tshuaj xyuas cov kev mob tshwm sim ntawm Dicinon yws, piv txwv li, ntawm qhov tshwm sim ntawm pob liab liab, mob plab. Tsis muaj leej twg hais txog qhov tsis zoo ntawm kev noj qab haus huv, vim tias thaum tsis siv tshuaj, tag nrho cov kev mob tshwm sim sai sai.
