"Bacteriophage Klebsiell": cov lus qhia thiab tshuaj xyuas

Cov txheej txheem:

"Bacteriophage Klebsiell": cov lus qhia thiab tshuaj xyuas
"Bacteriophage Klebsiell": cov lus qhia thiab tshuaj xyuas

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Hnub no qhov tseeb yog tias qhov kis ntawm cov kab mob sib kis tau ruaj khov thoob plaws hauv lub xyoo, tsis yog lub caij ntuj no txias tshwj xeeb thiab ntub tawm lub caij nyoog. Tam sim no qhov muaj peev xwm kis tau tus kab mob txaus ntshai rau cov neeg muaj kev tiv thaiv tsis muaj zog tseem nyob thoob plaws plaub lub caij, tsis hais huab cua.

Kab mob, uas ua rau muaj mob hnyav, feem ntau xav tau kev kho mob tshwj xeeb. Qhov no txhais tau hais tias nws tsis muaj txiaj ntsig los siv cov tshuaj dav dav los tawm tsam lawv. Rau kev kho mob kom zoo, yuav tsum tau siv cov neeg ua haujlwm tshwj xeeb, uas nws qhov kev ua feem ntau yog qhia rau cov neeg ua haujlwm ntawm ib tus kab mob sib kis.

Yog li, rau ib pawg ntawm cov kab mob Klebsiella, cov tshuaj "Bacteriophage Klebsiella" tau siv zoo. Kev tshuaj xyuas cov tshuaj tau lees paub qhov tshwj xeeb ntawm cov tshuaj no los tawm tsam ntau yam kab mob txaus ntshai.

tshuaj npe hu li cas? Yuav siv nws li cas thiab rau cov xwm txheej twg nws siv tau? Qhov no yuav yog hais txoghais lus hauv kab lus no.

Cov kab mob bacteriophage Klebsiella
Cov kab mob bacteriophage Klebsiella

Composition

"Klebsiella bacteriophage", qhov tseeb, yog ib qho tshuaj tiv thaiv kab mob tshwj xeeb uas cuam tshuam rau qee pawg kab mob - Klebsiella, uas ua rau muaj ntau yam kab mob loj thiab tuaj yeem ua rau muaj kev hem thawj rau tib neeg lub neej. Txawm hais tias nrog kev kho tsis raug, txoj hauv kev ntawm kev rov qab zoo yam tsis muaj teeb meem tsawg.

Cov khoom xyaw tseem ceeb ntawm cov tshuaj "Bacteriophage Klebsiella" yog purified phagolysate filtrate.

Ib daim foos

Cov tshuaj nyob rau hauv nqe lus nug yog muaj nyob rau hauv cov kua: nyob rau hauv daim ntawv ntawm ib tug ua hauj lwm tov uas yuav siv tau ob qho tib si rau cov tshuaj pleev ib ce, thiab raws li ib tug tov rau txhaj tshuaj, thiab raws li ib tug tshuaj qhov ncauj (yuav siv cov tshuaj kom raug. thiab nyob rau hauv dab tsi npaum li cas qhov no yuav tsum tau ua yuav tau piav nyob rau hauv tag nrho cov tsim nyog nthuav dav tom qab nyob rau hauv tsab xov xwm).

"Bacteriophage Klebsiella", raws li txoj cai, yog tsim nyob rau hauv ampoules nrog ib tug ntim ntawm tsib los yog kaum milliliters. Thiab cov ntim tshuaj muaj tsib lossis kaum ampoules txhua. Muaj lwm daim ntawv tso tawm - lub raj mis loj (lawv ntim feem ntau yog nees nkaum milliliters thiab tsim nyog rau kev kho mob mus sij hawm ntev). Ib pob muaj plaub lub raj mis ntawm cov tshuaj "Bacteriophage Klebsiella Purified".

bacteriophage klebsiell tshuaj xyuas
bacteriophage klebsiell tshuaj xyuas

Cov lus qhia rau kev siv

Nws yog ib qho tseem ceeb uas yuav tsum siv cov cuab yeej tag nrhoraws li cov lus qhia ua ke. Kev siv tshuaj "Bacteriophage" tawm tsam Klebsiella, raws li cov kws tshaj lij, zoo heev pab kom tshem tau cov kab mob kis los ntawm cov kab mob no. Tab sis nyob rau hauv kev sib raug zoo rau lwm yam kab mob, cov tshuaj nyob rau hauv nqe lus nug tsis muaj ib tug analogous nyhuv.

Yog li, "Klebsiella oxytoca. Bacteriophage" yuav pab tau zoo hauv kev sib ntaus tawm tsam ntau yam kab mob purulent-inflammatory cuam tshuam rau pob ntseg (otitis media), caj pas (pharyngitis), thiab qhov ntswg (sinusitis). Txoj kev kho no tseem yuav siv tau rau cov kab mob purulent-inflammatory uas nyob hauv lwm qhov ntawm lub cev thiab cov kab mob hauv nruab nrog cev. Peb tab tom tham txog cov kab mob kis kab mob, cystitis thiab lwm yam teeb meem nrog cov keeb kwm zoo sib xws. Hauv kev tawm tsam mob ntsws, "Bacteriophage of Klebsiella pneumonia" yuav ua tau zoo. Cov lus qhia kuj pom zoo kom siv cov tshuaj hauv nqe lus nug rau kev kho mob rhinoscleroma, ozena, thiab kab mob enteral.

Cov kev npaj no kuj tseem siv tau zoo txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau kis kab mob ntawm cov pab pawg no hauv ib chav rau txhua lub hom phiaj (suav nrog tsev kho mob).

Kev qhia bacteriophage Klebsiella pneumonia
Kev qhia bacteriophage Klebsiella pneumonia

Mechanism of action

Nws yog cov kab mob kab mob uas muaj zog tshaj plaws ntawm cov kab mob phem uas lawv tus kheej yog cov khoom tseem ceeb ntawm cov tshuaj hauv nqe lus nug. Lawv mechanism ntawm kev uamuaj nyob rau hauv cov nram no: tus kab mob no ntes ib tug xov tooj ntawm ib tug txawv teb chaws kab mob, uas nws muaj peev xwm cuam tshuam, thiab nyob rau hauv ib tug luv luv lub sij hawm ntawm nws tus kheej los ua ib feem ntawm lub cell genome, yog li cuam tshuam cov txheej txheem metabolic tshwm sim nyob rau hauv nws, thiab provoking txoj kev loj hlob. ntawm lub zog tshaib plab. Raws li qhov tshwm sim, cov kab mob txaus ntshai tuag, thaum kev loj hlob thiab kev tsim tawm ntawm cov kab mob kis tau nce ntxiv.

Nws yog ib qho tseem ceeb uas yuav tsum nco ntsoov tias cov tshuaj no tsuas yog siv tau rau cov kab mob Klebsiella nkaus xwb thiab tsis muaj txiaj ntsig rau lwm yam kab mob.

Qhov txiaj ntsig tseem ceeb kuj yog qhov tseeb tias thaum kho nrog cov tshuaj hauv nqe lus nug, kev txhim kho ntawm dysbacteriosis tsis tuaj yeem ua tsis tau, thiab qhov no ua rau kev ua haujlwm ntawm lub plab zom mov.

Cov tshuaj tiv thaiv kab mob siab hauv lub cev tsuas yog ntev npaum li qhov xav tau los tawm tsam tus kabmob. Thaum tag nrho cov kab mob phem raug rhuav tshem, tus naj npawb ntawm phages raug txo qis, thiab lub cev tiv thaiv kab mob tau tshem tawm ntawm nws tus kheej.

Kev qhia bacteriophage Klebsiella polyvalent
Kev qhia bacteriophage Klebsiella polyvalent

Yuav siv li cas

Txoj hauv kev tseem ceeb ntawm phage kom tsawg yog qhov ncauj. Txawm hais tias cov kws kho mob feem ntau sau cov tshuaj yuav tsum tau coj mus rau hauv lub cev los yog siv hauv zos ntawm qhov chaw kis kab mob. Tus txheej txheem ntawm kev nkag mus yog muab los ntawm tus kws kho mob tshwj xeeb, nyob ntawm tus kheej tus yam ntxwv ntawm cov kab mob ntawm ib tus neeg mob.

Cov tshuaj yuav tsum tau noj peb zaug hauv ib hnub, thaum tswj kev so40-60 feeb ntawm cov tshuaj thiab zaub mov.

Cov koob tshuaj ua haujlwm yog nyob ntawm lub hnub nyoog ntawm tus neeg mob. Piv txwv li, tus me nyuam mos (txog li rau lub hlis) yuav tsum tsis txhob tau txais ntau tshaj tsib milliliters ntawm "Bacteriophage" yog tias noj qhov ncauj thiab tsis pub ntau tshaj kaum milliliters - rectally.

Cov koob tshuaj ntau tshaj rau tus menyuam hnub nyoog qis dua ib xyoos yuav tsum tsis pub tshaj kaum tsib milliliters, thiab rau cov menyuam yaus hnub nyoog qis dua peb xyoos - nees nkaum milliliters ntawm cov tshuaj.

Cov neeg mob hnub nyoog qis dua yim xyoo tuaj yeem noj txog peb caug milliliters ntawm cov tshuaj ua haujlwm. Rau txhua tus, qhov siab tshaj plaws yog plaub caug milliliters.

Qee yam kab mob, xws li mob ntsws, yuav tsum tau siv cov tshuaj hauv nqe lus nug hauv daim ntawv ntawm aerosol, uas yuav muab cov txiaj ntsig zoo tshaj plaws ntawm kev kho mob.

Kev noj tshuaj, raws li txoj cai, yuav tsum tsis pub dhau ob lub lis piam. Txawm li cas los xij, lub sijhawm yuav tsum tau teem sijhawm los ntawm tus kws kho mob ib leeg, vim tias lawv raug cuam tshuam los ntawm qhov mob hnyav thiab qhov chaw ntawm qhov mob ntawm tus neeg mob lub cev.

Kev tiv thaiv kab mob nrog kev pab ntawm phages yog ua los ntawm kev noj tshuaj ib hnub ib zaug xwb.

bacteriophage Klebsiella polyvalent tshuaj xyuas
bacteriophage Klebsiella polyvalent tshuaj xyuas

YContraindications

Raws li cov kws tshaj lij, cov tshuaj no tuaj yeem siv nyab xeeb los ntawm leej twg, tsis hais nws keeb kwm, vim tias tsis muaj ib qho contraindication rau kev siv tshuaj hauv nqe lus nug tau pom. Txawm li cas los xij, nws yog ib qho tseem ceeb uas yuav tsum ua tib zoo saib xyuas cov koob tshuaj pom zoo los ntawm tus kws kho mob thiab cov lus qhia. Qhov no yuav ua rau koj noj qab nyob zoo.

Side effects

"Klebsiella bacteriophage" cov kws tshaj lij hu nws muaj kev nyab xeeb tag nrho rau txhua tus neeg mob uas tuaj yeem kho nrog tus neeg sawv cev nug. Tsis muaj cov kev tshawb fawb hauv chaw soj nstuam tau qhia tias muaj kev phom sij lossis tsis zoo rau cov neeg mob kho nrog tshuaj.

Daim ntawv thov nta

Zoo li txhua yam tshuaj, "Bacteriophage" muaj qee yam uas yuav tsum tau xav txog thaum siv nws:

  • Piv txwv li, nws yog ib qho tseem ceeb rau kev kuaj xyuas tshwj xeeb ua ntej pib ntawm chav kawm, uas yuav tsum paub meej tias qhov rhiab heev ntawm cov kab mob mus rau phages, kev siv uas tau npaj tseg.
  • Kev kho tshuaj tua kab mob tsis yog qhov cuam tshuam rau kev kho ntxiv nrog "Bacteriophage". Qhov no yuav tsis txo qhov kev ua tau zoo ntawm cov tshuaj hauv nqe lus nug.
  • Nws yog ib qho tseem ceeb kom ntseeg tau tias cov tshuaj yuav khoom yog qhov tseeb, tsis muaj sediment. Yog tias cov tshuaj hauv ampoule lossis vial tsis ua raws li cov cai no, nws tsis pom zoo kom siv nws. Cov tshuaj zoo li no twb tau poob nws cov txiaj ntsig zoo thiab tseem tuaj yeem ua rau muaj kev phom sij rau tus neeg mob.
  • Qee lub sij hawm "Bacteriophage" yog siv los kho qhov qub ntawm daim tawv nqaij lossis cov mucous membrane, uas tau cuam tshuam thaum siv qee yam tshuaj (xws li tshuaj tua kab mob). Nyob rau hauv rooj plaub no, ua ntej siv, ntxuav cov tawv nqaij los yogmucosa, uas yuav tsum tau kho nrog dej huv ntau npaum li sai tau. Yog tias qhov no tsis ua tiav, ces cov tshuaj tua kab mob yuav rhuav tshem cov phages uas tsim cov tshuaj, uas theem nws cov txiaj ntsig.

Raws li cov kws tshawb fawb, cov tshuaj hauv nqe lus nug tsis muaj kev cuam tshuam rau kev muaj peev xwm tsav tsheb kom nyab xeeb, tsis ua rau kev xav qeeb, tsis cuam tshuam kev mloog thiab tsis ua rau muaj kev ntxhov siab. Cov poj niam hauv txoj haujlwm thiab cov niam laus kuj tuaj yeem siv cov tshuaj, tab sis tsuas yog nyob rau hauv kev saib xyuas nruj ntawm tus kws kho mob paub txog.

Klebsiella oxytoca bacteriophage
Klebsiella oxytoca bacteriophage

Kev sib tham nrog lwm yam tshuaj

Ib qho txiaj ntsig tseem ceeb ntawm "Klebsiella bacteriophage polyvalent" kev tshuaj xyuas yog lub peev xwm los siv cov tshuaj zoo tiag tiag hauv nqe lus nug ib txhij nrog kev kho mob nrog lwm cov tshuaj. Cov no suav nrog, piv txwv li, tshuaj tua kab mob lossis tshuaj tiv thaiv kab mob.

Storage condition

"Bacteriophage Klebsiella" cov lus qhia pom zoo kom khaws cia hauv qee qhov xwm txheej uas yuav tsis cuam tshuam rau nws cov khoom siv tshuaj. Qhov no txhais tau hais tias qhov kub ntawm qhov chaw khaws tshuaj yuav tsum nyob ntawm ob mus rau yim degrees Celsius. Nws yog tsis yooj yim sua kom overheat lossis khov cov khoom, qhov no ua rau nws cov khoom tsis muaj zog.

Cov tshuaj muaj lub neej txee tsuas yog kaum ob lub hlis txij li hnub tau tsim. Yog tias lub sijhawm muaj npe tshaj, ces cov tshuaj yuav tsis ua haujlwm.ntawm lub cev kom zoo thiab nws cov txiaj ntsig yuav dhau los ua qhov tsis txaus ntseeg.

txheej txheem muag

Nws yog ib qho tseem ceeb uas yuav tsum nco ntsoov tias hauv ntau thaj chaw kev kho mob ntawm Klebsiella nrog cov kab mob bacteriophages tuaj yeem ua tau tsuas yog tom qab kev teem caij ntawm koj tus kws kho mob thiab tau txais nws cov lus pom zoo, suav nrog txhua tus yam ntxwv ntawm koj tus kab mob. Yog li ntawd, yuav tsum tau muaj cov kws kho mob tshwj xeeb kom yuav "Klebsiella bacteriophage polyvalent". Cov lus qhia tsis pom zoo siv cov tshuaj yam tsis tau sab laj nrog kws kho mob.

Kev kho mob ntawm Klebsiella nrog bacteriophages
Kev kho mob ntawm Klebsiella nrog bacteriophages

Reviews

Qhov txiaj ntsig tseem ceeb ntawm cov tshuaj tau piav qhia, cov kws tshaj lij xav txog qhov pib sai sai ntawm qhov pom tshwm sim, tsis muaj kev phiv thiab muaj peev xwm siv tshuaj hauv zos "Bacteriophage Klebsiella". Kev tshuaj xyuas txog nws los ntawm cov neeg mob lees paub tsis yog nws cov txiaj ntsig, tab sis tseem muaj kev nyab xeeb rau cov neeg uas txiav txim siab siv nws hauv lawv txoj kev kho mob.

Txhua tus paub tias muaj teeb meem kev noj qab haus huv niaj hnub no nyob ntawm tus neeg mob lub hnub nyoog me me. Txhua tus muaj cai tau txais kev kho mob zoo tshaj plaws. Qhov no yog qhov yuav dhau los ua lub hauv paus ntawm kev noj qab haus huv lub cev yav tom ntej. Tsis txhob txuag koj tus kheej txoj kev noj qab haus huv thiab kev noj qab haus huv ntawm koj cov neeg koj hlub. Thaum xaiv cov khoom zoo tshaj plaws, yuav "Bacteriophage".

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