Tsim los ntawm kev puas tsuaj ntawm hemoglobin thiab lwm yam proteins hauv cov ntshav thiab muaj nyob rau hauv cov ntshav, cov kua tsib xim, uas muaj xim daj-xim av, yog bilirubin. Nws cov qauv hauv cov ntshav tsis zoo ib yam: hauv cov menyuam yaus hnub nyoog qis dua ib hlis thiab cov neeg laus, qhov concentration ntawm cov xim no yog 8.5-20.5 µmol / l, hauv cov menyuam mos - txog li 205 µmol / l thiab ntau dua.
Yog li nce bilirubin hauv cov menyuam yug tshiab yog qhov nkag siab heev. Tus menyuam tsis tuaj yeem ua pa ntawm nws tus kheej thaum nyob hauv plab. Oxygen nkag mus rau hauv nws cov ntaub so ntswg nrog kev pab los ntawm cov qe ntshav liab, uas muaj fetal hemoglobin. Nws dhau los ua qhov tsis tsim nyog tom qab tus menyuam yug los, raws li qhov tshwm sim ntawm qhov tawg. Yog li ntawd, muaj kev nce bilirubin hauv cov menyuam mos. Nws yog dawb, nyob rau hauv lwm yam lus, indirect pigment, uas yog insoluble. Lub raum tsis tuaj yeem tshem tawm nws, yog li nws nkag mus rau hauv cov ntshav kom txog thaum cov enzymes hauv lub cev loj tuaj. Thaum qhov no tshwm sim, indirect bilirubin hloov mus rau direct bilirubin thiab tawm.
siab bilirubin hauv cov menyuam yug tshiab ua rau daj ntseg. Nyob rau hauv feem ntau cov me nyuam mos, nws yog physiological, manifests nws tus kheej li ntawm 3-4 hnub tom qab yug me nyuam, thiab nws thiaj li ploj mus yam tsis muaj ib tug kab, tsis ua rau muaj kev puas tsuaj rau lub cev. Jaundice feem ntau tshwm sim nyob rau hauv cov neeg mob uas muaj intrauterine hypoxia ntawm fetus, ntshav qab zib hauv leej niam. Qhov nce siab bilirubin hauv cov menyuam mos tuaj yeem ua rau muaj kev loj hlob ntawm cov kab mob jaundice. Cov laj thawj rau nws cov tsos mob suav nrog kev puas tsuaj ntawm cov qe ntshav liab, kev txiav txim siab caj ces, kev tsis sib haum xeeb ntawm leej niam thiab tus menyuam raws li Rh yam lossis hom ntshav, lub siab puas tsuaj ntawm cov kab mob sib kis, plab hnyuv, plab hnyuv, hormonal ntshawv siab, kev cai lij choj kab mob siab, thiab lwm yam.. Tshawb nrhiav seb qhov tshwm sim ntawm qhov tshwm sim ntawm pathology, tuaj yeem tsuas yog tus kws kho mob tshwj xeeb, raws li cov txiaj ntsig ntawm kev kuaj ntshav thiab lwm yam kev tshawb fawb.
Bilirubin encephalopathy
Yog tias muaj bilirubin ntau ntxiv hauv cov menyuam mos, muaj kev phom sij ntawm nws qhov nkag mus rau hauv lub paj hlwb thiab ua rau muaj tshuaj lom rau nws. Xws li ib tug txaus ntshai mob rau lub paj hlwb thiab lub paj hlwb hu ua bilirubin, los yog nuclear, encephalopathy. Nws cov tsos mob yog tshwm sim nyob rau hauv ib tug txo nyob rau hauv lub nqus reflex nyob rau hauv tus me nyuam mos, txo cov ntshav siab, tsaug zog heev, thiab convulsions. Thaum muaj hnub nyoog rau lub hlis, tus me nyuam yuav muaj kev hnov lus tsis zoo, tuag tes tuag taw, kev puas hlwb.
nce bilirubin: kev kho mob
Yog tias koj tus menyuam muaj mob jaundice, kev kho mob phototherapy yog qhov kev kho mob zoo tshaj plaws. Nrog kev pab los ntawm lub teeb raug, dawb bilirubin hloov mus rau hauv tsis muaj tshuaj lom, uas yog ces tawm hauv cov zis thiab quav hauv 12 teev. Txawm li cas los xij, phototherapy tuaj yeem ua rau muaj kev phiv xws li cov quav xoob thiab tawv nqaij tawv. Tom qab nres phototherapy, lawv ploj. Tsis tas li ntawd, kom tshem tawm cov kab mob jaundice sai dua, nws raug nquahu kom pub niam mis ntau zaus. Vim yog colostrum, thawj cov quav (meconium) tau tawm ntawm lub cev nrog bilirubin. Nyob rau hauv cov ntaub ntawv ntawm pathological jaundice, ntxiv rau kev siv cov kev kho mob saum toj no, txoj kev kho yuav tsum tau ua los ntawm kev tshem tawm qhov ua rau tus kab mob.
