"Bergolac": analogues, indications rau siv, muaj pes tsawg leeg, phiv

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"Bergolac": analogues, indications rau siv, muaj pes tsawg leeg, phiv
"Bergolac": analogues, indications rau siv, muaj pes tsawg leeg, phiv

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Tshuaj "Bergolac" yog ib qho inhibitor ntawm prolactin ntau lawm, uas kuj yog ib tug dopamine receptor agonist. Daim ntawv ntau npaum ntawm cov tshuaj no yog ntsiav tshuaj: dawb, biconvex oblong, nrog rau kev pheej hmoo. Lawv tau ntim rau hauv 8 lossis 2 daim. nyob rau hauv lub raj mis polymer - 1 pc. hauv thawv.

Dab tsi yog qhov muaj pes tsawg leeg ntawm Bergolak? 1 ntsiav tshuaj muaj cov khoom xyaw nquag - cabergoline, nrog rau qee cov khoom ntxiv: anhydrous lactose (lactopress), leucine, magnesium stearate.

cabergoline los yog bergolac uas zoo dua
cabergoline los yog bergolac uas zoo dua

tshuaj muaj txiaj ntsig

Cabergoline yog ib qho ergoline derivative, dopamine receptor agonist uas inhibits prolactin secretion. Cov tshuaj no muab stimulation ntawm dopamine D2 receptors nyob rau hauv lub lactotropic hlwb ntawm pituitary caj pas.

Raws li cov lus qhia rau kev siv, "Bergolac" nyob rau hauv ntau npaum muaj ib tug dopaminergic nyhuv ntawm lub hauv paus hom, txo cov ntsiab lus ntawm prolactin nyob rau hauv cov ntshav, restores fertility thiab kev coj khaub ncaws. Hauv cov poj niam, vim qhov txo qistheem ntawm prolactin yog rov qab los ntawm kev tsim tawm ntawm gonadotropins, thiab nyob rau hauv nruab nrab ntawm kev coj khaub ncaws, luteinizing hormone yog tsim, nrog kev pab los ntawm cov anovulatory cycles ploj, cov tshuaj estrogen hauv cov ntshav nce, qhov hnyav ntawm hyperandrogenic (pob txuv., hirsutism) thiab hypoestrogenic (osteoporosis, kua dej tuav, hnyav nce) cov tsos mob txo.

Hauv cov txiv neej, cabergoline txo cov yam tshwm sim los ntawm hyperprolactinemia: impotence (raws li kev txo qis ntawm prolactin, qhov concentration ntawm testosterone nce), txo libido, gynecomastia, lactorrhea. Muaj qhov rov qab txhim kho ntawm pituitary adenomas thiab cov tsos mob tshwm sim los ntawm lawv (mob taub hau, ua haujlwm tsis zoo thiab pom kev pom).

Cov tshuaj no pab txo qis cov ntsiab lus ntawm prolactin hauv cov neeg uas muaj pseudoprolactinoma lossis prolactinoma. Qhov concentration ntawm prolactin txo qis dua 3 teev tom qab noj, tshuav 14-21 hnub. Cov tshuaj muab qhov txo qis hauv qib ntawm prolactin ntawm 2-4 lub lis piam ntawm kev kho mob.

bergolak nqi
bergolak nqi

Cov lus qhia rau kev siv

"Bergolac" yog tshuaj rau cov kab mob hauv qab no:

  • kev tawm tsam lossis kev tiv thaiv tom qab lactation;
  • kho cov mob cuam tshuam nrog hyperprolactinemia, suav nrog amenorrhea, anovulation, galactorrhea, oligomenorrhea;
  • syndrome "lub eeb Turkish khoob", uas yog ua ke nrog hyperprolactinemia;
  • prolactin-secreting pituitary adenomas (micro- thiab macroprolactinomas), idiopathic hyperprolactinemia.

npe ntawm contraindications

Cov tshuaj yog contraindicated nyob rau hauv xws li mob:

  • under 16;
  • galactose intolerance;
  • glucose-galactose malabsorption;
  • lactase deficiency;
  • siab rhiab heev rau ergot alkaloids;
  • tsis nkag siab rau cabergoline thiab lwm yam tshuaj hauv kev tsim.

Qhov no yuav tsum tau txiav txim siab ua ntej teem sijhawm.

Bergolac cov lus qhia rau kev siv
Bergolac cov lus qhia rau kev siv

Kev txais tos zoo

Raws li cov lus qhia rau kev siv, "Bergolac" tau sau tseg nrog kev ceev faj rau cov kab mob ntawm cov hlab plawv, cov hlab ntshav siab thaum cev xeeb tub (xws li preeclampsia), kev tswj hwm ib txhij ntawm cov tshuaj tiv thaiv hypertensive (tseem ceeb ntawm orthostatic hypotension), nrog rau qhov tsis txaus. daim siab, plab hnyuv los ntshav, peptic ulcers, cov ntaub ntawv loj ntawm kev txawj ntse thiab kev puas siab puas ntsws, nyob rau hauv lub xub ntiag ntawm fibrotic hloov nyob rau hauv lub ua pa system thiab lub plawv (pleurisy, valvulopathy los yog pleural fibrosis).

Thaum pib xeeb tub?

Tom qab noj cov tshuaj, kev xeeb tub tuaj yeem pib tom qab ib hlis. Yog hais tias tus neeg mob cev xeeb tub thaum lub sij hawm kho, yuav tsum tau txiav txim siab rau kev txiav txim siab ntawm kev txiav cov tshuaj, suav nrog cov txiaj ntsig thiab kev pheej hmoo.

Cov khoom no tsis qhia rau cov poj niam uas xav pub niam mis, yog li ntawd, yog tias tsim nyog kho cabergoline, kev pub mis yuav tsum nres.

bergolac lossis dostinex uas zoo dua
bergolac lossis dostinex uas zoo dua

Kev qhia

Pills yog siv rau qhov ncauj. Pom zoo noj ntau npaum:

  1. Txhawm rau tiv thaiv kev lactation tom qab yug menyuam: thawj hnub tom qab yug menyuam - 1 mg ib zaug.
  2. Kev pub mis niam: 0.25mg ob zaug ib hnub 12 teev sib nrug. Duration ntawm kev nkag - 2 hnub. Vim lub peev xwm rau orthostatic hypotension, ib koob tshuaj yuav tsum tsis pub tshaj 0.25 mg.
  3. Kev kho mob ntawm cov mob uas cuam tshuam nrog hyperprolactinemia: thawj koob tshuaj - 0.5 mg ib lub lis piam, ib zaug lossis muab faib ua 2 koob tshuaj nrog lub sijhawm 3 hnub.

Cov teebmeem ntawm Bergolac

Tshuaj yuav ua rau cov kev mob tshwm sim no:

  1. CNS: tsaug zog ntau dhau, mob taub hau, kiv taub hau, qaug zog, syncope, asthenia, paresthesia, kev nyuaj siab.
  2. Lub plawv, hlab ntsha: ntws tawm, valvulopathy, palpitations, vasospasm, orthostatic hypotension, txo cov ntshav siab.
  3. Kev zom zaub mov: mob plab, cem quav, dyspepsia, gastritis, daim siab ua haujlwm tsis zoo.
  4. Kev tsis haum tshuaj: hypersensitivity.
  5. Lwm yam: nqaij cramps, epistaxis, mastodynia, alopecia, transient hemianopia, edema, teeb meem ua pa, pleural fibrosis.
bergolac los yog agalates
bergolac los yog agalates

Tus nqi

Tus nqi ntawm "Bergolak" yog kwv yees li 860 rubles. Nws nyob ntawm thaj av thiab chaw muag tshuaj.

Analogues ntawm cov tshuaj no

Lub ntsiab analogues ntawm Bergolak yog:

  • Agalates.
  • "Cabergoline".
  • Dostinex.

Nws yog ib qho tseem ceeb kom nkag siab tias tsuas yog tus kws kho mob yuav tsum xaiv tus hloov.

Agalates

Qhov no yog cov tshuaj Israeli tsim, dopamine receptor agonist raws li cabergoline, hluavtaws ergot alkaloid. Cov tshuaj inhibits zus tau tej cov prolactin. Lub hauv paus ntsiab lus ntawm kev ua haujlwm ntawm lub ntsiab tseem ceeb suav nrog kev txhawb nqa ntawm dopamine receptors hauv hypothalamus. Ntawm cov koob tshuaj ntau dua li qhov yuav tsum tau ua kom txo qis prolactin ntau lawm, cov tshuaj ua rau lub hauv paus ntawm dopaminergic nyhuv vim yog kev txhawb nqa ntawm dopamine D2 receptors.

Cov nyhuv ntawm cov tshuaj yog nyob ntawm koob tshuaj. Kev txo qis hauv cov ntsiab lus prolactin feem ntau pom tom qab 3 teev thiab txuas ntxiv mus rau 2-3 lub lis piam, thiab yog li ntawd, txhawm rau txhawm rau lactation, ib koob tshuaj ntawm cov tshuaj no feem ntau yog txaus. Thaum kho hyperprolactinemia, qib ntawm prolactin hauv cov ntshav stabilizes tom qab 2-4 lub lis piam. Qib ib txwm ntawm prolactin tuaj yeem nyob hauv lub cev rau ob peb lub hlis.

bergolac muaj pes tsawg leeg
bergolac muaj pes tsawg leeg

Nws tuaj yeem nyuaj rau kev txiav txim siab yam xav tau - "Agalates" lossis "Bergolak". Lub ntsiab tseem ceeb ntawm thawj zaug muaj cov yam ntxwv zoo heev thiab tsis cuam tshuam rau basal zus tau tej cov cortisol thiab lwm yam tshuaj hormones pituitary. Qhov tsuas yog pharmacodynamic tshwm sim uas tsis yog vim kev kho mob yog suav tias yog qhov txo qis hauv cov ntshav siab. Qhov zoo tshaj plaws hypotensive nyhuv yog feem ntau pom 6 teev tom qab noj. Qhov ntsuas ntawm qhov txo qis thiab qhov tshwm sim ntawm hypotensiveCov teebmeem nyob ntawm qhov ntau npaum ntawm cov tshuaj.

Cov lus qhia rau kev sau tshuaj thiab cov npe ntawm cov contraindications rau cov tshuaj no zoo ib yam li cov lus qhia hauv cov lus qhia rau kev siv tshuaj "Bergolac".

Tus nqi ntawm cov tshuaj no analogue yog hais txog 1150 rubles.

Cabergoline

Dab tsi ntxiv yog suav nrog hauv cov npe analogues ntawm "Bergolak"? Cov tshuaj "Cabergoline" (Lavxias teb sab tshuaj) yog tsim nyob rau hauv lub hauv paus ntawm lub active tshuaj ntawm tib lub npe. Nws yog ib qho ergoline derivative, dopamine receptor agonist uas inhibits prolactin secretion. Cov tshuaj no muab stimulation ntawm dopamine D2 receptors nyob rau hauv lub lactotropic hlwb ntawm lub caj pas pituitary. Ib qho analogue ntawm "Bergolac" "Cabergoline" nyob rau hauv ntau npaum muaj ib tug dopaminergic nyhuv ntawm lub hauv paus hom, txo cov ntsiab lus ntawm prolactin nyob rau hauv cov ntshav, restores lub voj voog ntawm kev coj khaub ncaws thiab fertility.

Hauv cov poj niam, vim qhov txo qis hauv qib ntawm prolactin, lub pulsating zus tau tej cov gonadotropins rov qab thiab nyob rau hauv nruab nrab ntawm lub cev ntas, luteinizing hormone yog tsim, nrog kev pab los ntawm cov anovulatory cycles ploj, cov tshuaj estrogen. Cov ntsiab lus hauv cov ntshav nce, qhov hnyav ntawm hyperandrogenic (pob txuv, hirsutism) thiab hypoestrogenic (osteoporosis, kua dej tuav, qhov hnyav nce) cov tsos mob.

Hauv cov txiv neej, cabergoline txo cov yam tshwm sim los ntawm hyperprolactinemia: impotence (raws li kev txo qis ntawm prolactin, qhov concentration ntawm testosterone nce), txo libido, gynecomastia, lactorrhea. Kev txhim kho rov qab ntawm pituitary adenomas thiab cov tsos mob tshwm sim los ntawm lawv tau sau tseg.(mob taub hau, teb thiab qhov muag pom kev cuam tshuam).

Kev noj cov tshuaj analogue ntawm "Bergolac" yuav pab txo qis cov ntsiab lus ntawm prolactin hauv cov neeg mob pseudoprolactinoma lossis prolactinoma. Qhov concentration ntawm prolactin txo qis dua 3 teev tom qab noj, tshuav 14-21 hnub. Cov tshuaj muab qhov txo qis hauv qib ntawm prolactin ntawm 2-4 lub lis piam ntawm kev kho mob.

Dab tsi zoo dua - "Cabergoline" lossis "Bergolac", tus kws kho mob yuav qhia rau koj. Tus nqi ntawm thawj qhov sib txawv ntawm 680-770 rubles ib pob.

Dostinex

Tshuaj "Dostinex" yog Italian analogue ntawm "Bergolak". Dopamine receptor agonist raws li cabergoline, hluavtaws ergot alkaloid. Cov tshuaj inhibits zus tau tej cov prolactin. Lub hauv paus ntsiab lus ntawm kev ua haujlwm ntawm lub ntsiab tseem ceeb suav nrog kev txhawb nqa ntawm dopamine receptors hauv hypothalamus. Ntawm cov koob tshuaj ntau dua li qhov yuav tsum tau ua kom txo qis prolactin ntau lawm, cov tshuaj ua rau lub hauv paus ntawm dopaminergic nyhuv vim yog kev txhawb nqa ntawm dopamine D2 receptors.

Bergolac analogues npe
Bergolac analogues npe

Cov nyhuv ntawm cov tshuaj yog nyob ntawm koob tshuaj. Kev txo qis hauv cov ntsiab lus prolactin feem ntau pom tom qab 3 teev thiab txuas ntxiv mus rau 2-3 lub lis piam, thiab yog li ntawd, txhawm rau txhawm rau lactation, ib koob tshuaj ntawm cov tshuaj no feem ntau yog txaus. Thaum kho hyperprolactinemia, qib ntawm prolactin hauv cov ntshav stabilizes tom qab 2-4 lub lis piam. Qib ib txwm ntawm prolactin tuaj yeem nyob hauv lub cev rau ob peb lub hlis.

Ntau tus kuj xav paub qhov zoo dua "Bergolak" lossisDostinex. Cov tshuaj no zoo ib yam li ntau yam.

Lub ntsiab lus tseem ceeb ntawm Dostinex analogue muaj cov khoom siv zoo heev thiab tsis cuam tshuam rau basal secretion ntawm cortisol thiab lwm yam tshuaj hormones pituitary. Qhov tsuas yog pharmacodynamic tshwm sim uas tsis yog vim kev kho mob yog suav tias yog qhov txo qis hauv cov ntshav siab. Cov nyhuv hypotensive loj tshaj plaws yog pom, raws li txoj cai, 6 teev tom qab kev tswj hwm. Qib ntawm kev txo qis thiab qhov zaus ntawm qhov tshwm sim ntawm cov nyhuv hypotensive nyob ntawm qhov ntau npaum ntawm cov tshuaj.

Qhov analogue ntawm "Bergolak" tus nqi hauv cov khw muag tshuaj yog kwv yees li 660 rubles.

Alaktin

Nov yog ib qho tshuaj uas txwv tsis pub lactation. Nws yog ib qho hluavtaws ergot alkaloid thiab muaj qhov ntev thiab hais tawm ntawm cov tshuaj prolactin-txo cov nyhuv. Cov khoom xyaw nquag: cabergoline (0.5 mg).

"Alactin" yog siv qhov ncauj thaum noj mov.

Cov koob tshuaj rau kev tiv thaiv tom qab lactation yog 1 mg ib zaug hauv thawj hnub tom qab yug menyuam.

Txhawm rau txo cov lactation uas twb muaj lawm, 0.25 mg txhua 12 teev rau ob hnub (1 mg tag nrho) raug pom zoo.

Tus qauv ntau npaum li cas hauv kev kho mob hyperprolactinemic yog 0.5 mg ib zaug / lub lis piam lossis 0.25 mg ob zaug hauv ib lub lis piam. Yog tias tsim nyog, cov koob tshuaj tuaj yeem maj mam nce ntxiv (nyob rau hauv kev saib xyuas ntawm tus kws kho mob) - los ntawm 0.5 mg / lis piam ntawm txhua hli kom txog thaum tau txais cov txiaj ntsig kho mob. Tus qauv tshuaj noj yog 1mg ib lub lis piam thiab tuaj yeem nyob ntawm 0.25mg txog 2mg ib lub lis piam.

Max koob - 3mg/day.

Reviews

Cov neeg mob uas tawm ntawm qhov kev tshuaj xyuas ntau ntawm cov tshuaj "Bergolac" thiab nws cov analogues yog cov poj niam uas tau muab cov tshuaj no rau cov kab mob hormonal ntawm qhov chaw mos thiab txhawm rau kom tsis txhob lactation. Tus so yog cov neeg tau txais kev kho mob rau lwm yam kab mob uas tshwm sim los ntawm hyperprolactinemia.

Kev tshuaj xyuas feem ntau yog qhov zoo. Cov neeg mob nco ntsoov tias cov tshuaj ntawm pawg kws tshuaj no muaj txiaj ntsig zoo, tso cai rau koj kom ua tiav qhov kev xav tau ntawm kev kho mob sai sai. Qhov tsuas yog qhov tsis zoo ntawm cov tshuaj no yog cov kev mob tshwm sim loj heev, ntawm cov neeg mob uas tsis txaus siab feem ntau tau pom - mob hnyav dyspepsia, kiv taub hau, tshee, tsis pom kev pom, quav quav, tawm tsam vegetovascular dystonia, ntshav siab, asthenic. syndrome, tsis qab los noj mov, cramps ntawm ceg thiab lwm yam.

Pom zoo: