Ntau yam kab mob thiab kab mob hauv lub cev ua tsis tau yog tias tsis siv tshuaj tua kab mob. Ib pawg ntawm cov tshuaj no tua cov kab mob phem thiab cov kab mob. Ib qho ntawm cov tshuaj tua kab mob uas paub zoo yog "Gentamycin sulfate". Nws suav hais tias yog tshuaj tua kab mob uas muaj ntau yam kev siv thiab siv los kho tib neeg thiab tsiaj.
Daim ntawv thiab muaj pes tsawg leeg ntawm cov tshuaj
Tshuaj nyob rau hauv daim ntawv ntawm 4% tshuaj rau kev txhaj tshuaj thiab qhov muag tee. Cov khoom tseem ceeb hauv cov tshuaj muaj pes tsawg leeg yog gentamicin sulfate ntawm koob tshuaj 4 mg ib milliliter. Nws belongs rau pawg aminoglycosides thiab suav hais tias yog ib qho tshuaj tua kab mob dav dav.
Cov tshuaj muaj cov tshuaj tiv thaiv kab mob thiab cov kab mob bactericidal. Nws muaj kev ua haujlwm siab tiv thaiv anaerobic gram-negative kab mob thiab gram-positive cocci. Tom qab txhaj tshuaj intramuscular, cov tshuaj sai sai absorbed. Cov nyhuv siab tshaj plaws yog ua tiav hauv ib teev tom qab txhaj tshuaj. Yuav luag tsis khi rau cov ntshav protein kiag li. Cov tshuaj tua kab mob yog muab faib rau hauv cov kua dej extracellular thoob plaws hauv lub cev thiab lub cev. Cov tshuaj tsis yog metabolized thiab feem ntautshem tawm los ntawm ob lub raum, me ntsis - nrog cov kua tsib. Cov tshuaj "Gentamicin sulfate" muaj cov cuab yeej ntawm kev hla lub placental barrier. Daim ntawv thov, kev mob tshwm sim - tag nrho cov no yuav tsum tau kawm ua ntej kev npaj kho mob.
Kev qhia
Cov tshuaj tau sau tseg rau cov kab mob sib kis thiab mob hauv lub cev, uas yog tshwm sim los ntawm cov tshuaj tua kab mob-sensitive microorganisms. Rau kev tswj xyuas parenteral:
- cystitis;
- mob cholecystitis;
- purulent lesions ntawm daim tawv nqaij;
- kub hnyiab ntawm ntau qib;
- Ypyelonephritis;
- cystitis;
- kab mob ntawm pob qij txha thiab pob txha ntawm ib qho xwm txheej kis;
- sepsis;
- peritonitis;
- pneumonia.
Kev siv sab nraud:
- furunculosis;
- folliculitis;
- seborrheic dermatitis;
- mob kub hnyiab;
- qhov txhab ntawm ntau yam etiologies;
- sycosis.
Tau thov cov ntsiab lus:
- blepharitis;
- blepharoconjunctivitis;
- dacryocystitis;
- conjuntivit;
- -Keratitis.
Nrog rau cov kab mob zoo li no, "Gentamicin sulfate" yog siv. Cov lus qhia rau kev siv yog nyob nruab nrab ntawm lub tsev muag tshuaj pob nrog cov tshuaj.
Contraindications:
- hypersensitivity rau tshuaj tua kab mob;
- mob hnyav ntawm lub raum thiab lub siab;
- cuam tshuam hauv kev ua haujlwm ntawm lub suab paj nruag;
- bearing;
- pub mis niam.
Tseem tsis muaj tshuaj tua kab mob"Gentamicin sulfate" nyob rau hauv ampoules rau uremia.
KOJ
Cov tshuaj tau muab tshuaj ib leeg rau txhua tus neeg mob. Qhov ntau npaum yog nyob ntawm qhov hnyav ntawm cov txheej txheem thiab hypersensitivity rau tus neeg sawv cev. Nyob rau hauv ib lub sij hawm, los ntawm 1 mus rau 1.7 mg ib kg ntawm qhov hnyav yog muab. Cov tshuaj yog txhaj rau hauv cov hlab ntsha lossis intramuscularly. Cov tshuaj yog siv ob mus rau plaub zaug ib hnub twg. Qhov ntau npaum li cas ib hnub yuav tsis ntau tshaj 5 mg. Lub sijhawm kho yog 1.5 lub lis piam.
Cov menyuam yaus tom qab ob xyoos tau txais cov tshuaj ntau zaus hauv ib hnub hauv qhov nyiaj ntawm 1 mg rau ib kg ntawm lub cev hnyav. Rau cov menyuam yaus hnub nyoog qis dua ib hlis, qhov koob tshuaj txhua hnub tsis tuaj yeem ntau dua 2-5 mg ib kg ntawm lub cev hnyav. Cov tshuaj tua kab mob yog siv ntau zaus hauv ib hnub.
Rau kev siv tshuaj pleev ib ce, tshuaj pleev qhov muag yog instilled 1 poob txhua ob teev. Rau kev siv sab nraud, cov tshuaj tau sau tseg txog peb zaug hauv ib hnub. Rau cov neeg uas muaj lub raum tsis ua haujlwm, nyob ntawm daim duab kho mob, cov tshuaj "Gentamicin sulfate" raug kho. Qhov muag tee yog instilled ncaj qha mus rau hauv lub hnab ntawm lub conjunctiva ntawm tus kab mob qhov muag.
Sib tham nrog lwm yam cuab yeej
Nws tsis pom zoo kom noj cov tshuaj hauv qab no ua ke:
- Vancomycin;
- YCephalosporin;
- "Ethacrynic acid";
- "Indomethacin";
- tshuaj loog;
- tshuaj tua kab mob;
- pab diuretics.
Ua ntej kev npaj kho mob, nws yuav tsum ua tib zoo kawm txog kev sib cuam tshuam ntawm lwm cov tshuaj thiab cov tshuaj tua kab mob "Gentamycin sulfate".
Kev tsis saib xyuas cov lus pom zoo tuaj yeem ua rau muaj kev cuam tshuam hauv qab no:
- nausea;
- ntua;
- nce hauv cov ntshav bilirubin;
- ntshav qab zib;
- thrombocytopenia;
- leukemia;
- migraine;
- kiv taub hau;
- Yproteinuria;
- mob ntawm lub vestibular apparatus.
Tseem tuaj yeem ua rau muaj kev tsis haum "Gentamycin sulfate". Kev poob qis thiab kev daws teeb meem hauv qhov tsis tshua muaj tuaj yeem ua rau Quincke's edema lossis anaphylactic shock, uas yog fraught nrog cov teeb meem loj. Thaum siv tshuaj tua kab mob, nws yuav tsum tau saib xyuas cov haujlwm ntawm lub raum, hnov lus thiab vestibular apparatus.
"Gentamicin sulfate" - tshuaj tua kab mob rau tsiaj
Tsiaj txhu tuaj yeem ua rau kis kab mob. Txhawm rau kho tus tsiaj muaj mob, siv tshuaj tua kab mob tshwj xeeb. Cov tshuaj no suav nrog "Gentamycin sulfate". Nws belongs rau cov pab pawg ntawm aminoglycosides thiab yog sib xyaw ntawm C1, C2 thiab C1a gentamicins. Cov tshuaj muaj xws li gentamicin ntawm ib koob ntawm 40 thiab 50 mg hauv ib milliliter ntawm kev daws. Cov khoom yog khaws cia ntawm qhov kub tsis tshaj 25 degrees, hauv qhov chaw qhuav thiab siv tsis tau rau cov menyuam yaus. Ob xyoos - lub txee lub neej ntawm cov tshuaj "Gentamycin sulfate". Cov lus qhia rau kev siv rau cov tsiaj yuav qhia meej txog cov lus qhia thiab ntau npaum li cas ntawm cov tshuaj.
Action
Cov tshuaj muaj ntau qhov cuam tshuam thiab muaj zog tiv thaiv kab mob gram-positive thiab gram-negative microorganisms. Tom qab kev qhia txog cov tshuaj, nws nyob rau hauv ib lub sij hawm luv luvnkag mus rau hauv txhua lub cev thiab lub cev. Tom qab ib teev, nws cov haujlwm siab tshaj plaws tau pom thiab txuas ntxiv rau 8 teev. Nws raug tshem tawm feem ntau hauv cov zis thiab hauv qhov me me hauv cov quav ntawm tus tsiaj.
Cov tshuaj yog muab rau kev kho mob ntawm lub plab, plab hnyuv, peritonitis, meningitis, pyelonephritis thiab lwm yam kab mob hauv cov tsiaj. Cov tshuaj yog muab ob zaug ib hnub twg nrog lub sij hawm ntawm 10 teev. Ib qho tshuaj kho qhov ncauj "Gentamicin sulfate" rau cov tsiaj kuj raug sau tseg.
KOJ
Rau kev kho cov nees, cov tshuaj tua kab mob yog muab tshuaj intramuscularly ntawm koob tshuaj 2.5 mg ib kilogram ntawm lub cev qhov hnyav. Lub sijhawm kho yog los ntawm 3 mus rau 5 hnub. Hauv cov nyuj, qhov koob tshuaj yog muab rau ntawm tus nqi ntawm 3 mg ib kilogram ntawm lub cev hnyav rau 5 hnub. Tsis tas li ntawd, cov tshuaj tuaj yeem noj ntawm qhov ncauj ntawm qhov ntau npaum li 8 mg ib kilogram ntawm lub cev qhov hnyav.
npua cov tshuaj yog txhaj tshuaj intramuscularly ntawm tus nqi ntawm 4 mg rau 1 kg ntawm qhov hnyav. Lub sijhawm kho yuav tsum tsis pub tshaj peb hnub. Qhov ncauj, cov tshuaj yog siv ntawm ib koob ntawm 4 mg ib kilogram ntawm lub cev qhov hnyav rau 5 hnub. Cov dev thiab miv tau txhaj tshuaj intramuscularly nrog 2.5 mg ntawm kev daws ib kilogram ntawm lub cev hnyav. Kev kho mob yuav siv sijhawm txog xya hnub.
Thaum siv qhov ncauj, cov tshuaj tsis nqus hauv plab, tab sis tsuas yog tom qab 12 teev hauv cov hnyuv. Tsuas yog tus kws kho tsiaj tuaj yeem muab tshuaj tua kab mob "Gentamycin sulfate" intramuscularly. Cov lus qhia rau tsiaj piav qhia yuav ua li cas muab tshuaj.
Cov lus qhia tshwj xeeb
Nws yog txwv tsis pub siv tshuaj tua kab mob nrog rau lwm pab pawgnephrotic agents, tshwj xeeb tshaj yog nrog rau lub raum pathology thiab tsis hnov lus. Tsiaj tua tsiaj raug tso cai tsuas yog peb lub lis piam tom qab qhov kawg ntawm cov tshuaj. Cov cuab yeej tsis cuam tshuam rau cov kab mob yooj yim tshaj plaws, cov kab mob thiab cov kab mob anaerobic. Tsuas yog ib tus kws kho tsiaj xwb thiaj li tuaj yeem suav cov koob tshuaj "Gentamycin sulfate 4%" thiab kho tus tsiaj.
Tshuaj "Gentamicin"
Cov tshuaj muaj nyob rau hauv pab pawg ntawm cov tshuaj tua kab mob aminoglycoside, uas tau siv dav los kho ntau yam kab mob. Cov cuab yeej muaj cov teebmeem hauv qab no rau lub cev:
- bactericidal;
- anti-inflammatory;
- muaj kev ua haujlwm siab tiv thaiv kab mob gram-positive thiab gram-negative.
Cov tshuaj muaj nyob rau hauv daim ntawv ntawm kev daws. Tom qab txhaj tshuaj intramuscular, cov tshuaj yog sai absorbed rau hauv cov ntaub so ntswg ntawm tag nrho lub cev. Qhov loj tshaj bioavailability yog pom tom qab ib nrab teev. Ib nrab ntawm cov nyiaj tau tso tawm hauv cov zis tom qab 3 teev. Nkag mus los ntawm cov placenta, yog li nws tsis pom zoo kom sau cov tshuaj "Gentamicin" thiab nws cov analogue "Gentamicin sulfate" thaum cev xeeb tub. Cov lus qhia rau kev siv cov khoom no muaj cov ntaub ntawv tseem ceeb thiab cov lus piav qhia ntawm cov tshuaj tua kab mob.
Indications thiab contraindications
Kev kho cov kab mob sib kis thiab mob, uas yog tshwm sim los ntawm cov kab mob nkag mus rau cov khoom xyaw nquag, tuaj yeem ua tiav siv "Gentamicin". Cov tshuaj yog siv rau parenteral, sab nraud thiab hauv zos siv.
Contraindications:
- hypersensitivity rau pawg aminoglycoside;
- bearing;
- lactation;
- mob raum tsis ua haujlwm;
Ua ntej pib txoj kev kho mob, koj yuav tsum ua tib zoo kawm tag nrho cov contraindications rau kev siv tshuaj tua kab mob "Gentamicin" thiab "Gentamicin sulfate".
KOJ
Cov tshuaj tau sau rau ntawm tus kheej, koob tshuaj nyob ntawm qhov hnyav ntawm tus kab mob. Rau intramuscular thiab intravenous tswj, tus neeg sawv cev yog xam nyob rau hauv ib koob ntawm 1 mus rau 1.7 mg ib kilogram ntawm lub cev qhov hnyav ib zaug. Cov tshuaj yog muab ob los yog peb zaug ib hnub twg. Qhov siab tshaj plaws txhua hnub pub rau tus neeg laus yuav tsum tsis txhob ntau tshaj 5 mg / kg, thiab rau cov me nyuam - 3 mg ib kilogram ntawm lub cev hnyav. Cov tshuaj yog muab rau 7 hnub. Qhov muag tee yog siv peb zaug ib hnub twg thiab ib tee yog instilled ncaj qha rau hauv lub qhov muag cuam tshuam. Cov tshuaj tua kab mob yog siv rau sab nraud plaub zaug hauv ib hnub. Nyob rau hauv lub raum pathology hnyav, cov tshuaj tau sau tseg raws li daim duab kho mob, thiab cov tshuaj tuaj yeem hloov kho. Rau cov menyuam yaus, qhov nyiaj pub dawb txhua hnub nyob ntawm lub hnub nyoog thiab qhov xwm txheej ntawm lub cev.
Kev Sib Tham Tshuaj
Gentamicin tsis pom zoo ua ke nrog cov tshuaj hauv qab no:
- Vancomycin;
- YCephalosporin;
- "Ethacrynic acid";
- "Indomethacin";
- tshuaj tua kab mob;
- tshuaj loog;
- diuretics.
Cov tshuaj "Gentamicin" thiab cov tshuaj "Gentamicin sulfate 4%" muaj tib yam muaj pes tsawg leeg thiab cov lus qhia rau kev siv. Ob leegCov khoom lag luam muaj cov kab mob ntau ntxiv thiab tiv thaiv kab mob.
Tshuaj "Gentamicin-Ferein"
Cov tshuaj belongs rau pawg aminoglycosides thiab tau dav siv los kho ntau lub cev thiab lub cev. Nws tau nce kev ua haujlwm tawm tsam gram-positive thiab gram-negative anaerobic kab mob. Nws muaj cov nyhuv bactericidal. Tom qab intramuscular thiab intravenous tswj, cov tshuaj tua kab mob yog absorbed rau hauv tag nrho cov nruab nrog cev thiab cov ntaub so ntswg ntawm lub cev.
40 feeb tom qab txhaj tshuaj, cov tshuaj ncav cuag nws qhov kev ua haujlwm siab tshaj plaws, uas kav ntev li 12 teev. Cov tshuaj tsis metabolized thiab tawm hauv cov zis. Muaj peev xwm hla lub placental barrier.
Indications thiab contraindications
Cov tshuaj no yog siv rau kev siv parenteral, hauv zos thiab sab nraud siv los kho cov kab mob sib kis.
Contraindications:
- xeeb tub;
- pub mis niam;
- pathology ntawm lub raum thiab siab;
- kev nyuaj siab;
- Acoustic neuritis.
Cov tshuaj "Gentamicin-Ferein"
Rau cov neeg laus, cov tshuaj yog muab rau hauv ib qho ntawm tsis pub ntau tshaj 5 mg ib kilogram ntawm lub cev hnyav ib hnub twg. Hauv ib koob, koob tshuaj yog los ntawm 1 txog 1.7 mg rau 1 kg ntawm tus neeg mob qhov hnyav. Cov kev kho mob nyob ntawm qhov hnyav ntawm cov txheej txheem thiab nyob ntawm 7 mus rau 10 hnub. Cov tshuaj yog muab ob lossis peb zaug hauv ib hnub
Rau cov menyuam yaus, qhov ntau npaum li cas yog 3 mg ib kilogram ntawm lub cev hnyav rauib qho kev taw qhia. Cov tshuaj yog txhaj ob zaug ib hnub twg. Hauv cov neeg mob lub raum tsis txaus, qhov ntau npaum li cas ntawm cov tshuaj tua kab mob tau hloov kho tas li thiab nyob ntawm cov kev qhia hauv chaw kho mob.
Qhov muag te yog siv txhua 4 teev thiab muab tso rau hauv qhov muag cuam tshuam ib tee ib zaug. Sab nraud, txoj kev kho yog muab peb lossis plaub zaug hauv ib hnub.
Cov kev phiv tshwm sim:
- nausea;
- ntua;
- nce bilirubin;
- ntshav qab zib;
- leucopia;
- drowsy;
- migraine;
- mob ntawm lub vestibular apparatus;
- daws;
- tshuaj tsis haum, mus txog rau angioedema.
Gentamicin sulfate 4% cov tshuaj yuav muaj cov kev mob tshwm sim zoo sib xws thaum kho cov kab mob sib kis hauv lub cev.
Tshuaj xyuas cov tshuaj raws li gentamicin sulfate
Tshuaj tsis yog cov tshuaj tua kab mob tiam tshiab, tab sis lawv zoo heev thiab tam sim no siv los kho cov kab mob microbial. Yog li ntawd, muaj ntau yam khoom lag luam hauv khw muag tshuaj uas muaj gentamicin. Cov no tsis yog tsuas yog cov kev daws teeb meem rau kev txhaj tshuaj, tab sis kuj cream, tshuaj pleev, qhov muag tee. Cov tshuaj cuam tshuam rau cov ntaub ntawv genetic embedded nyob rau hauv lub hlwb ntawm cov kab mob. Cov khoom xyaw nquag yog absorbed rau hauv cov ntaub so ntswg ntawm lub cev nyob rau hauv ib tug luv luv lub sij hawm thiab pib nws antibacterial nyhuv.
Feem ntau, cov tshuaj tau txais txiaj ntsig zoo, tab sis tuaj yeem ua rau muaj kev fab tshuaj. Tsis tas li ntawd, cov tshuaj tua kab mob tuaj yeem noj thaum yug los. Muaj ib lub tswv yim tshwj xeeb rau qhov no.koob tshuaj. Cov tshuaj tua kab mob no tau siv dav hauv cov tshuaj kho tsiaj. Nws pab tsiaj kom tshem tau cov kab mob thiab normalize lub plab thiab hnyuv.
Qee zaum cov tshuaj "Gentamicin" tuaj yeem ua rau tsis hnov lus, thiab qhov no yog nws qhov tsis zoo. Los ntawm kev kawm tag nrho cov kev tshuaj xyuas, tshwj xeeb tshaj yog cov kws kho mob, koj tuaj yeem nkag siab tias cov tshuaj tua kab mob muaj zog npaum li cas. Nws muaj kev ua haujlwm siab tiv thaiv Gram-positive thiab Gram-negative anaerobic kab mob. Tsis tas li ntawd nyob rau hauv lub complex yog muab rau kev kho mob ntawm pneumonia thiab meningitis. Nws yog ib qho tsim nyog yuav tsum ua tib zoo saib xyuas qhov ntau npaum ntawm cov tshuaj kom tsis txhob muaj kev phiv. Raws li ntau tus kws tshaj lij, cov tshuaj "Gentamycin sulfate" yog tshuaj lom. Nws qhov kev siv tas li tuaj yeem cuam tshuam rau kev ua haujlwm ntawm txhua lub cev. Cov tshuaj tua kab mob yuav tsum tsis txhob siv yam tsis muaj kev qhia los ntawm tus kws tshaj lij.
