Prolactin (Lactogenic hormone, lactotropic hormone, mammotropic hormone) yog ib qho ntawm cov tshuaj hormones ntawm lub caj pas pituitary. Estrogens thiab dopamine cuam tshuam ncaj qha rau nws cov khoom tsim tawm.
Nws lub ntsiab lus rau ib tug poj niam, ib txoj kev los yog lwm qhov, yog txuas nrog kev ua me nyuam, muaj peev xwm xeeb tub thiab yug me nyuam. Nws yog ib qho tseem ceeb heev uas yuav tsum paub tias cov tshuaj no yog lub luag haujlwm rau, tus qauv ntawm prolactin, los saib xyuas nws cov ntsuas hauv cov ntshav txhawm rau txheeb xyuas cov kab mob hauv lub sijhawm.
YProlactin muaj nuj nqi
Yog li prolactin lub luag haujlwm yog dab tsi? Feem ntau ntawm cov haujlwm ntawm cov tshuaj no muaj feem xyuam rau kev yug me nyuam:
- zoo li tus yam ntxwv ntawm kev sib deev theem nrab hauv cov ntxhais;
- nyob rau hauv lub quarter kawg ntawm cev xeeb tub yog koom nrog hauv kev loj hlob ntawm cov qog mammary thiab nce hauv cov ducts hauv lawv;
- pib tsim cov colostrum tom qab yug menyuam, uas hloov mus rau hauv cov mis nyuj, sau cov qog mammary ntawm kev pub mis;
- thaum lactation thaiv qhov pib ntawm ovulation thiab tom qab conception;
- qib siab ntawm prolactin, qhov mob qis dua ntawm cov poj niam hauvlub sijhawm yug me nyuam, vim hais tias prolactin muaj cov nyhuv analgesic;
- tswj kev coj khaub ncaws;
- hauv cov txiv neej, prolactin koom nrog hauv kev tsim thiab loj hlob ntawm spermatozoa, yog lub luag haujlwm rau kev sib deev noj qab haus huv;
- koom nrog hauv lub cev tiv thaiv kab mob.
Raws li koj tuaj yeem pom los ntawm kev ua haujlwm, kev tsim khoom thiab qhov tsim nyog ntawm cov ntsiab lus ntawm cov tshuaj hormones hauv cov ntshav yog qhov tseem ceeb tsis yog rau kev noj qab haus huv tag nrho, tab sis kuj rau kev yug menyuam thiab pub mis rau menyuam.
Muaj 3 hom ua rau nce prolactin:
- Physiological.
- Pharmacological - cov no yog qhov tshwm sim ntawm kev noj tshuaj.
- Pathological yog kev ua txhaum hauv endocrine system ntawm lub cev.
Lub cev nce hauv cov ntshav prolactin
Nce prolactin tseem tsis tau muaj kab mob. Cov yam ntxwv ntawm lub cev zoo li qub tuaj yeem cuam tshuam nws qhov kev hloov pauv ntau. Raws li kev cuam tshuam ntawm lwm cov tshuaj hormones - estrogen - prolactin nce thaum cev xeeb tub, thiab nrog rau txhua lub peb hlis ntuj nws qib nce. Qhov nce hauv estrogen ncaj qha cuam tshuam qhov nce hauv prolactin. Rau tus poj niam cev xeeb tub, qhov no yog qhov tsim nyog txhawm rau txhawm rau pub tus menyuam tom qab. Thaum cev xeeb tub, txawm tias qhov tseeb tias prolactin nce, cov txheej txheem lactation tseem tsis tuaj yeem pib, vim tias cov ntshav tseem muaj ntau ntawm progesterone, qhov txo qis yuav pib tom qab cov placenta tso tawm thaum lub sijhawm yug menyuam. Nws yog ib txwm ua rau cov qib prolactin siab thaum pub niam mis thiab.
Kuj nce qhov pituitary hormonepom thaum cev xeeb tub, tawm dag zog, sib deev, thaum muaj kev ntxhov siab thiab mob, tshaib plab.
Nyob nruab hnub muaj qhov sib txawv ntawm cov ntsiab lus ntawm prolactin hauv cov ntshav, piv txwv li, tom qab sawv ntxov nws siab dua tom qab 3 teev sawv ntxov.
Pathological thiab pharmacological ua rau thiab qhov tshwm sim ntawm nce prolactin hauv cov poj niam
- qog nqaij hlav hauv qog pituitary.
- kab mob siab thiab cirrhosis ntawm daim siab.
- kab mob autoimmune.
- polycystic zes qe menyuam
- rau lub raum thiab lub siab tsis ua haujlwm.
- YHypothyroidism.
- Acromegaly.
- Anorexia.
- YUterine fibroids.
- Kev quav cawv thiab quav yeeb tshuaj.
EndometriosisEndometriosis
Muaj cov tshuaj uas tuaj yeem nce qib prolactin ua ib qho kev phiv. Cov no yog cov tshuaj tiv thaiv kab mob uas muaj feem ntau ntawm estrogen, antiemetics, antipsychotics, Reserpine, Verapamil.
Ib qho ntawm qhov tshwm sim tsis zoo ntawm kev nce qib prolactin yog kev xeeb tub. Kev ua txhaum ntawm kev coj khaub ncaws, tsis xwm yeem ovulation lossis nws tsis tuaj yeem ua rau lub cev tsis muaj peev xwm. Qhov no tshwm sim nyob rau hauv ib feem peb ntawm cov poj niam uas ua tsis tau tiav kev sim xeeb tub.
Qhov tshwm sim ntawm hyperprolactinemia tuaj yeem sib txawv. Cov kab mob qee zaum cuam tshuam rau kev ua haujlwm ntawm lub hauv nruab nrab paj hlwb. Nws tuaj yeem ua rau muaj kev nyuaj siab loj, insomnia. Kev sib deev ncaj ncees qee zaum hnov qhov kev ntshaw ntawm kev sib deev.
Cov neeg mob uas yuav tsum tau kuaj ntshav rau prolactin
Thaum twg thiaj pub cov tshuaj prolactin? Yog vim li cas rau kev txheeb xyuas yuav muaj raws li hauv qab no:
- Poj niam thiab txiv neej tsis muaj menyuam. Primary los yog Secondary.
- kev coj khaub ncaws tsis xwm yeem, amenorrhea - tsis muaj kev coj khaub ncaws ntau tshaj rau lub hlis.
- Uterine los ntshav.
- tso tawm los ntawm cov qog mammary - galactorrhea, feem ntau ua ke nrog mastopathy.
- kab mob thyroid.
- Irreducibly rog.
- Kev loj hlob ntawm lub ntsej muag plaub hau.
- mob taub hau, lub siab hloov pauv, kev nyuaj siab.
- Kev tsis muaj roj hauv qhov chaw mos.
- mob khaub thuas hnyav.
- Cov tsos mob ntawm pob txha pob txha vim leaching ntawm calcium los ntawm cov ntshav.
- Txiv neej erectile kawg.
- Lub mis loj hauv cov txiv neej.
Table of Prolactin cov cai
Nws tus nqi yog cuam tshuam los ntawm kev xeeb tub, hnub ntawm kev coj khaub ncaws (qhov ze rau ntawm ovulation, qhov siab dua cov tshuaj hormones). Dab tsi yuav tsum yog tus qauv ntawm prolactin hauv cov ntshav? Nyob rau lub sijhawm sib txawv ntawm tus poj niam lub neej nws tus kheej. Sab nraud stimuli, kev ua kom lub cev ntau dhau, kev xav muaj zog, noj zaub mov thiab qee yam tshuaj kuj cuam tshuam rau cov tshuaj hormones. Kev tsim khoom siab tshaj plaws tshwm sim txij li 1 teev sawv ntxov txog 5 teev sawv ntxov.
Lub rooj qhia cov qauv ntawm prolactin los ntawm hnub nyoog thiab lub sijhawm sib txawv ntawm tus poj niam lub neej.
| Lub sijhawm | Norm, ng/ml |
| cev xeeb tub (los ntawm 8 lub lis piam) thiab lactation | 35-385 |
| Cov poj niam muaj menyuam hnub nyoog | 4-22, 8 |
| Cov poj niam thiab cov poj niam tom qab menopause | 19-20 |
Qhov tseem ceeb ntawm Prolactin rau txiv neej
Hauv cov txiv neej, nce prolactin cuam tshuam qhov txo qis hauv testosterone synthesis, uas txo qis zog, libido thiab ua rau muaj menyuam tsis taus. Cov qog mis tuaj yeem loj hlob thiab txawm tias cov mis nyuj tuaj yeem tso tawm. Tus qauv ntawm prolactin hauv cov txiv neej yog 3-15 ng / ml.
Dab tsi yog qhov txo qis hauv prolactin qhia
Qib ntawm cov tshuaj lactotropic tej zaum yuav qis dua li qub. Qhov no tshwm sim nrog cov kab mob xws li Sheehan's syndrome, tshwm sim los ntawm pituitary insufficiency. Yog hais tias ib tug poj niam overstay nws cev xeeb tub, ces prolactin kuj yuav txo nyob rau hauv nws cov ntshav.
Yuav ua li cas thiaj kuaj tau prolactin
Ntshav rau kev tshuaj xyuas yog muab los ntawm cov hlab ntsha, 2-3 teev tom qab pw tsaug zog, tsis hais hnub ntawm lub voj voog (qhov tshwm sim yuav muab piv rau hnub ntawm lub voj voog).
Kev npaj kev ntsuas yog txwv tsis pub sib deev, kev tawm dag zog lub cev, raug tshav kub lossis txias 3 hnub ua ntej xa khoom. Txwv tsis pub noj kas fes, khoom qab zib, tshem tawm overeating. da dej kub tsis tau, mus da dej.
Thaum twg prolactin rov qab noj? Raws li tau piav saum toj no, cov ntsiab lus ntau ntawm cov tshuaj hormones yuav txawv nyob ntawm ntau yam sab nraud thiab sab hauv. Yog tias, tom qab kuaj kuaj, kuaj pom qhov nce hauv cov qauv ntawm prolactin hauv cov ntshav, nws yuav tsum tau noj dua rau tsawg kawg 3 lub sijhawm coj khaub ncaws ntxiv.
Tsis tas li ntawd, tom qab tus kws kho mob decrypts cov ntaub ntawv txheeb xyuas, nws yuav tsim nyog kom paub meejKev kuaj mob ntawm cov thyroid caj pas, ultrasound ntawm lub plab zom mov, cov qog mammary, kev txiav txim siab ntawm cov ntshav qab zib. Yog tias tus neeg mob muaj qhov tsis pom kev, lawv raug xa mus rau tus kws kho mob ophthalmologist.
Nrog rau qib tseem ceeb ntawm prolactin, suav lossis sib nqus resonance imaging yog raug sau tseg los kuaj lossis tshem tawm cov qog. Me me pituitary adenoma pom nyob rau hauv 15% ntawm cov pejxeem thiab tsis cuam tshuam kev noj qab haus huv.
Kev kho mob ntawm hyperprolactinemia
Kev kho tus kheej yuav tsum tsis txhob ua, koob tshuaj raug xaiv los ntawm tus kws kho mob endocrinologist. Txoj kev tseem ceeb ntawm kev kho mob yog tshuaj. Feem ntau cov txheej txheem no ntev heev, nws yuav tsis tuaj yeem txo qis qib ntawm cov tshuaj hormones sai sai, lub sijhawm kwv yees sib txawv mus txog rau lub hlis. Yog tias lub hom phiaj ntawm kev kho mob yog cev xeeb tub, kev kho yuav txuas ntxiv mus txog ib xyoos.
Kev kho mob tsom rau:
- txo cov tshuaj hormones kom zoo;
- restoration ntawm kev coj khaub ncaws thiab ovulation;
- normalize fertility;
- tumor txo.
Cov tshuaj tseem ceeb suav nrog 3 tiam:
- "Bromocriptine", "Parodel" (derivatives ntawm ergot alkaloids).
- Norprolac (Quinagolide).
- Dostinex (Cabergoline).
Cov tshuaj no yog cov pab pawg ntawm dopamine receptor agonists (dopaminenomimetics), lawv muaj cov kev xaiv sib txawv ntawm prolactin receptors, thiab yog li sib txawv nyob rau lub sijhawm ua haujlwm thiab ua haujlwm ntev. Lawv cov koob tshuaj raug xaiv ib tus zuj zus los ntawm tus kws kho mob, pib kho nrog tsawg npaum li cas. Ib zaugib hlis twg, nyob rau hauv kev tswj hwm ntawm kev kuaj ntshav, koob tshuaj maj mam nce ntxiv, coj qib ntawm prolactin mus rau qhov qub.
Feem ntau, thaum noj Bromocriptine, cov kev mob tshwm sim xws li xeev siab (nws yog qhov zoo dua tsis txhob noj nws ntawm lub plab khoob), tsaug zog, ntshav siab, kiv taub hau. Tab sis txij li thaum nws cov tshuaj lom neeg tau kawm ntau dua, thaum muab tshuaj thaum cev xeeb tub, nws yuav yog cov tshuaj xaiv. Kev mob tshwm sim ntawm Dostinex thiab Norprolac tsis tshua muaj suab. Tawm tsam keeb kwm yav dhau los ntawm kev kho mob, cov keeb kwm hormonal normalizes, lub peev xwm xeeb tub tau rov qab los, qhov loj ntawm cov qog txo qis, thiab cov tsos mob ntawm prolactin siab tau raug tshem tawm.
Yog tias kev kho tshuaj tsis txo cov neoplasm, txawm tias qhov koob tshuaj ntau tshaj plaws thiab hloov cov tshuaj tsis pab, tus neeg mob yuav raug sau ntau txoj hauv kev - phais lossis hluav taws xob.
Kev cuam tshuam phais mob tshwm sim nrog qhov txaus ntshai thiab raug mob tsawg, txij li cov qog raug tshem tawm los ntawm cov sinuses nrog rau qhov endoscope. Nws yog qhia rau qhov tsis muaj txiaj ntsig lossis tsis txaus ntawm cov tshuaj, qhov muag tsis pom kev loj hlob, kev loj hlob ntawm neoplasm hauv tus poj niam cev xeeb tub.
cov lus qhia ntxiv
Ntxiv rau kev kho mob nrog tshuaj, koj tuaj yeem soothing tshuaj ntsuab, xws li mint, txiv qaub balm, valerian, hop cones. Nws yog ib qho tseem ceeb uas yuav tsum saib xyuas kev pw tsaug zog thiab so kom txaus, sim noj kom raug, poob phaus, ua si kis las, tshem tawm cov cwj pwm phem. Txhob noj tshuaj uas ua rau muaj kev nce hauv prolactin.
Cov zaub mov uas yuav pab coj homon rov qab los sai dua yuav tsum muaj cov protein ntau,vitamin B6, folic acid, tyrosine thiab folate. Noj ntau cov legumes, zaub ntsuab, zaub tshiab thiab txiv hmab txiv ntoo, qhob cij, cov nqaij ntshiv, cov ntses noj qab haus huv thiab cov nqaij nruab deg, kuj qe, noob, noob flax, txiv ntseej.
Nws yog ib qho tseem ceeb tsis yog tsuas yog suav nrog cov khoom noj muaj txiaj ntsig hauv kev noj zaub mov xwb, tab sis kuj yuav tsum tsis suav nrog cov khoom noj uas ua rau cov prolactin nce ntxiv, qhov no tsis yog cov qhob cij tag nrho nrog cov poov xab, khoom qab zib, hnyuv ntxwm, cov khoom noj haus.
cev xeeb tub thiab prolactin
Qhov piav qhia ua rau thiab qhov tshwm sim ntawm kev nce prolactin hauv cov poj niam ua rau nws tsis muaj peev xwm xeeb tub. Tom qab ntau qhov kev sim ua tsis tiav, qhov laj thawj feem ntau yog nyob rau hauv qhov tsis sib haum hormonal. Yog li ntawd, ib tug poj niam tau paub txog qhov kev kuaj mob xws li hyperprolactinemia. Yog lawm, txo qis cov tshuaj hormones tsis yooj yim, tab sis tom qab normalization, ob kab txaij ntev ntev yuav tshwm sim ntawm qhov kev sim.
Tom qab pib cev xeeb tub, kev kho mob cuam tshuam thiab qib ntawm prolactin tsis raug ntsuas lawm, qhov ntsuas yuav siab npaum li cas. Cov tshuaj no kuj tseem xav tau los ntawm tus menyuam hauv plab rau kev loj hlob ntawm lub ntsws.
Thaum lub sijhawm pub niam mis, cov tshuaj no tseem nce siab, tsis yog rau tsis muaj dab tsi uas nws lub npe los ntawm Latin lactis - mis nyuj, uas prolactin yog lub luag haujlwm. Los ntawm txoj kev, nws yog vim nws tias qee cov menyuam yug los nrog cov qog mammary o, txij li cov tshuaj hormone nkag mus rau hauv lub cev hauv lub cev, txhua yam yuav rov qab los sai sai.
Ntawm qhov kawg ntawm kab lus
Kab lus no qhia tau hais tias prolactin muaj nuj nqis rau pebkab mob. Kev thov kom raws sij hawm mus rau gynecologist thiab endocrinologist, ua raws li lawv cov lus pom zoo yuav pab kom lub cev xeeb tub ntev, rov qab noj qab haus huv thiab lub neej zoo.
