Tus neeg sawv cev hu ua "Tranexamic acid" yog ib qho tshuaj tua kab mob antifibrinolytic uas muaj cov tshuaj tiv thaiv kab mob thiab tiv thaiv kev ua xua, nrog rau cov nyhuv hemostatic ntawm cov ntshav, uas cuam tshuam nrog kev nce hauv fibrinolysis. Lub hauv paus ntawm cov tshuaj no yog inhibition ntawm plasminogen activator thiab plasmin, inhibiting tsim ntawm active peptides thiab kinins, uas yog ncaj qha koom nyob rau hauv inflammatory thiab tsis haum tshuaj. Tsis tas li ntawd, tus neeg sawv cev xws li "Tranexamic acid" ua rau lub sijhawm thrombin ntev. Raws li cov yam ntxwv ntawm cov tshuaj pharmacokinetics ntawm cov tshuaj antifibrinolytic no, tom qab kev tswj hwm qhov ncauj, kwv yees li 30-50% ntawm nws thawj koob tshuaj yog absorbed, nrog rau qhov siab tshaj plaws plasma concentrations.tau sau tseg ib puas mus rau ib puas yim caum feeb tom qab siv. Cov nyhuv antifibrinolytic nyob rau hauv cov ntaub so ntswg tshwm sim rau kaum tsib mus rau kaum xya teev, thiab nyob rau hauv plasma rau xya mus rau yim teev tom qab siv cov tshuaj "Tranexamic acid". Tus nqi ntawm cov khoom no yog hais txog 1,300 rubles, thiab koj tuaj yeem yuav nws hauv yuav luag txhua lub tsev muag tshuaj.
Cov tshuaj antifibrinolytic muaj nyob rau hauv daim ntawv ntawm cov ntsiav tshuaj ntawm ob puas thiab tsib caug los yog tsib puas milligrams, nyob rau hauv daim ntawv ntawm cov tshuaj rau kev txhaj tshuaj, thiab kuj nyob rau hauv daim ntawv ntawm cov tshuaj npaj rau kev tswj qhov ncauj. Tag nrho cov tshuaj no zoo heev rau kev kho mob thiab tiv thaiv los ntshav, provoked los ntawm kev nce hauv tag nrho cov fibrinolysis. Piv txwv li, ib qho tshuaj hu ua "Tranexamic acid" feem ntau yog muab rau cov qog nqaij hlav qog nqaij hlav ntawm prostate lossis pancreas, leukemia, kev phais mob ntawm lub hauv siab hauv nruab nrog cev, thiab kab mob siab. Phau ntawv kev sib cais ntawm cov placenta thiab postpartum hemorrhage kuj muaj nyob rau hauv daim ntawv teev cov lus qhia rau kev teem caij. Tsis tas li ntawd, cov tshuaj "Tranexamic acid" yuav tsum tau siv rau hematuria, angioedema, allergic dermatitis, eczema, tshuaj lom thiab tshuaj ua pob liab vog, urticaria. Tsis tas li ntawd, cov tshuaj no tau nquag muab tshuaj rau pharyngitis, laryngitis, tonsillitis, stomatitis, qhov ntswg, uterine thiab gastric los ntshav, tshem tawm cov hniav hauv cov neeg mob uas muaj hemorrhagic diathesis. Nws kuj pab tau ntau heev, xws li"Tranexamic acid", nrog rau kev coj khaub ncaws, tus cwj pwm los ntawm kev tso tawm ntau.
Raws li cov yam ntxwv ntawm kev siv thiab ntau npaum li cas ntawm cov tshuaj, nyob rau hauv txhua rooj plaub lawv tau teem ib tus zuj zus, raws li ib qho kev kho mob. Txawm li cas los xij, raws li txoj cai, tsis pub ntau tshaj 1-1.5 grams raug tso cai noj ib zaug. Nyob rau hauv cov ntaub ntawv no, zaus ntawm kev siv yog los ntawm ob mus rau plaub zaug ib hnub twg, thiab lub sij hawm ntawm kev kho mob yog los ntawm peb mus rau kaum tsib hnub. Ib koob txhaj tshuaj yog 10–15 mg/kg.
Lub ntsiab contraindications rau kev siv cov tshuaj no yog cov mob xws li subarachnoid hemorrhage, thromboembolic syndrome, lub raum tsis ua hauj lwm, impaired xim xaav thiab tob vein thrombosis. Tsis tas li ntawd, koj yuav tsum tsis txhob siv cov tshuaj no nyob rau hauv cov ntaub ntawv ntawm tus kheej rhiab heev los yog cev xeeb tub. Cov kev mob tshwm sim cuam tshuam nrog kev noj cov tshuaj antifibrinolytic no suav nrog kiv taub hau, tsaug zog, hypotension, tachycardia, tsis muaj zog, thiab mob hauv siab.
