Cov tshuaj muaj cov nyhuv uas tshwm sim los ntawm kev ua kom nrawm ntawm cov txheej txheem metabolic tshwm sim hauv cov kab mob neurosensory thiab hauv myocardium. Ua ntej pib txoj kev kho, koj yuav tsum paub seb cov tshuaj "Trimetazidin-Biokom MV" yog dab tsi. Cov lus qhia rau kev siv, muaj pes tsawg leeg ntawm cov tshuaj - cov ntaub ntawv tseem ceeb uas koj yuav tsum tau nyeem.
daim ntawv tso tshuaj, nws cov khoom
Cov tshuaj yog los hloov cov khoom tso tawm, muaj nyob rau hauv daim ntawv ntawm cov ntsiav tshuaj coated, yog tsim los ntawm trimetazidine dihydrochloride. Lub hlwv muaj 10 ntsiav tshuaj, hauv ib pob lawv tuaj yeem yog los ntawm 1 txog 6. Ib ntsiav tshuaj muaj 35 mg ntawm cov khoom tseem ceeb. Formulated nrog magnesium stearate, povidone, aerosil, hypromellose thiab calcium hydrogen phosphate dihydrate.
Titanium dioxide, macrogol yog cov khoom ntawm cov ntsiav tshuaj plhaub"Trimetazidin-Biocom MV". Cov lus qhia rau kev siv qhia tias ntxiv rau cov tshuaj no, lub plhaub muaj hypromellose thiab liab hlau oxide.
Pharmacological action
Antihypoxic tus neeg saib xyuas tso cai rau koj rov qab cov metabolism hauv ib txwm rau cov hlwb uas qhov kev hloov pauv tsis zoo tau tshwm sim vim kev loj hlob ntawm cov kab mob pathological (ischemia, hypoxia). Cov ntsiav tshuaj tshem tawm qhov txo qis ntawm ATP hauv cov hlwb, txhim kho cov xwm txheej ntawm ion membrane raws, transmembrane txav ntawm sodium thiab potassium ions. Nws tuaj yeem tswj hwm cellular homeostasis thaum lub sijhawm kho nrog kev siv tshuaj "Trimetazidine-Biocom MV". Cov lus qhia rau kev siv qhia tias cov tshuaj txo tus nqi ntawm cov txheej txheem oxidative ntawm fatty acids tshwm sim, vim hais tias cov piam thaj ntau oxidation yog nqa tawm, thiab kev tiv thaiv myocardial los ntawm ischemia. Qhov kev txiav txim ntawm cov tshuaj yog raws li kev hloov cov txheej txheem oxidative los ntawm fatty acids mus rau qabzib.
Cov tshuaj, txhawb cov txheej txheem ntawm cov txheej txheem metabolic, muaj txiaj ntsig zoo rau cov kab mob neurosensory thiab lub plawv, txo qhov hnyav ntawm kev cuam tshuam hauv cov ionic transmembrane ntws thaum lub sij hawm kev loj hlob ntawm ischemia. Los ntawm kev ua haujlwm ntawm cov ntaub so ntswg ntawm lub plawv, cov tshuaj pab txo qis cov ntsuas xws li kev tsiv teb tsaws, infiltration ntawm polynuclear neutrophils. Hais txog qhov kev txiav txim ntawm cov tshuaj "Trimetazidin-Biocom MV", cov lus qhia rau kev siv muaj xws li cov ntaub ntawv uas muaj kev cuam tshuam zoo rau myocardium, puas.vim ischemia. Cov tshuaj no yeej tsis cuam tshuam rau hemodynamics.
YPharmacokinetics
Kev nqus tau tshwm sim yuav luag tag thiab sai. Kev sib txuas lus nrog plasma proteins yog qhov tsis tseem ceeb (16%), bioavailability Performance index yog 90%. Txij li lub sijhawm cov ntsiav tshuaj raug coj mus rau lub sijhawm thaum theem ntawm cov tshuaj nquag hauv lub cev ua siab tshaj, nws yuav siv sijhawm li ob teev. Nws paub tias cov tshuaj tau yooj yim dhau los ntawm cov kab mob histohematic. Kev tshem tawm ib nrab-lub neej yog kwv yees li tsib teev. Cov tshuaj raug tshem tawm ntawm lub cev los ntawm lub raum, feem ntau nws tsis hloov nws daim ntawv.
Kev qhia
"Trimetazidine-Biokom MV" (cov ntsiav tshuaj) cov lus qhia tso cai rau koj los siv rau kev kho mob mus ntev ntawm cov kab mob plawv. Nws lub hom phiaj yog qhia hauv cov xwm txheej hauv qab no:
- qhov xav tau kev tiv thaiv kev tiv thaiv thaum muaj mob angina;
- kiv taub hau txuam nrog vascular lesions;
- cochleo-vestibular disorders ntawm ib qho ischemic xwm (kev puas tsuaj ntawm lub cev hnov lus);
- chorioretinal vascular pathologies nrog ischemia.
Kev tiv thaiv ntawm angina pectoris tuaj yeem ua tau siv ib qho tshuaj lossis los ntawm kev siv cov kev kho mob nyuaj.
YContraindications
Hais txog cov xwm txheej thaum noj tshuaj "Trimetazidine-Biocom MV" yog qhov tsis xav tau, cov lus qhia rau kev siv,Kev tshuaj xyuas muaj cov ntaub ntawv qhia qhov ua tsis tau zoo ntawm kev kho mob nrog cov tshuaj hauv cov xwm txheej zoo li no:
- rhiab heev rau cov khoom tseem ceeb thiab lwm cov khoom xyaw ntawm cov khoom;
- pub mis niam;
- bearing period.
Vim tias kev nyab xeeb ntawm cov tshuaj hauv cov menyuam yaus (hnub nyoog qis dua 18 xyoo) thiab kev kho mob nrog nws txoj kev siv tsis tau tsim, cov tshuaj no tsis tau sau rau cov neeg mob li no.
Cov tshuaj yog contraindicated nyob rau hauv lub siab mob hnyav thiab lub raum tsis ua hauj lwm, nyob rau hauv uas xws li ib tug qhia raws li creatinine clearance yog ho txo (yog 15 ml / min los yog tsawg dua). Tsis tsuas yog indications thiab contraindications txiav txim qhov muaj peev xwm ntawm kev kho mob nrog Trimetazidine-Biocom MV. Tus nqi kuj tseem ua lub luag haujlwm tshwj xeeb thaum xaiv cov tshuaj rau kev kho mob. Peb mam li tham me ntsis tom qab.
Tshuaj kho mob
Qhov loj ntawm ib koob tshuaj yog txiav txim los ntawm tus kws kho mob (feem ntau tsis tsawg dua 40 mg, tab sis tsis ntau tshaj 60). 2-3 koob tshuaj yuav tsum tau nyob rau ib hnub. Lub sijhawm ntawm kev kho mob yog teem rau nyias nyias.
Side effects
Ua ntej koj pib txoj kev kho, koj yuav tsum paub koj tus kheej nrog qhov tshwm sim tsis zoo ntawm lub cev vim yog kev noj tshuaj Trimetazidine-Biocom MB ntsiav tshuaj. Cov lus qhia rau kev siv cov tshuaj uas yog raws li kev kho mob, cov kev mob tshwm sim muaj xws li kev ua xua, tshwm sim raws li khaus, thiab pob khaus ntawm daim tawv nqaij, thiab lwm yam.cov tshuaj tiv thaiv uas tsis zoo rau lub cev. Hauv kev kho mob, qee zaus, qee cov neeg mob muaj xeev siab, ntuav, thiab gastralgia.
Kev noj tshuaj ntau dhau tsis tau tshaj tawm thiab tsis zoo li yuav tshwm sim. Lub ntsej muag hyperemia thiab hypotension tuaj yeem tshwm sim los ntawm kev siv ntau tshaj qhov pom zoo.
Cov lus qhia tshwj xeeb
Kev kho mob tsis cuam tshuam nrog lub peev xwm tsav lossis koom nrog cov haujlwm uas xav tau cov lus teb sai ntawm lub cev thiab lub hlwb.
Cov tshuaj tsis haum rau kev kho mob angina tawm tsam thiab tsuas yog yuav tsum tau siv prophylactically los ntawm cov neeg mob uas raug mob angina.
Thaum kev kho mob rau cov neeg mob uas muaj kab mob plawv, muaj qhov txo qis hauv kev xav tau nitrates txhua hnub.
Tus nqi ntawm cov tshuaj, analogues, tshuaj xyuas
Yuav tsum tau kawm ua ntej pib kho nrog "Trimetazidine" cov lus qhia rau kev siv. Tus nqi kuj yog cov ntaub ntawv tseem ceeb thiab raug coj mus rau hauv tus account thaum xaiv cov tshuaj rau kev kho mob (tiv thaiv) ntawm teeb meem plawv (IHD). Tus nqi kwv yees ntawm cov tshuaj yog 100-165 rubles. rau 30 ntsiav tshuaj thiab 189-208 rubles. rau 60 ntsiav tshuaj.
Raws li kev sib piv, koj tuaj yeem siv "Preductal", "Antisten" lossis "Trimet". Tej zaum kev kho mob nrog tshuaj "Medarum", "Rimecor". Tus kws kho mob tuaj yeem hloov cov tshuaj los ntawm kev sau tshuaj Precard, Angiosil, Trimitard MV. Muaj peev xwm kho nrog Triducard,"Predizin", "Trimectal" lossis "Metagard". Kev txiav txim los ntawm kev tshuaj xyuas, qhov nrov tshaj plaws analogue yog Preductal, cov tshuaj no zoo, tab sis nws raug nqi ntau dua Trimetazidine. Cov lus qhia rau kev siv, tus nqi qhia tau hais tias nws muaj txiaj ntsig zoo rau kev kho mob nrog tshuaj, tshuaj xyuas kom paub meej tias cov kev kho mob zoo li no.
Hauv kev tshuaj xyuas cov tshuaj, nws tau tshaj tawm tias cov tshuaj tshem tawm qhov mob hauv lub plawv zoo, nws ua haujlwm zoo kawg nkaus. Raws li qhov tshwm sim ntawm kev noj tshuaj, raws li cov neeg mob thiab cov kws kho mob, cov kev hloov pauv zoo tau sau tseg, piv txwv li, lub cev ntawm cov neeg uas tau txais kev kho mob pom tau tias lub cev ua haujlwm zoo dua. Ntau tus neeg hais tias tom qab ob peb hnub ntawm kev kho mob, lawv ua tsis taus pa ploj, tachycardia ploj, thiab ntshav siab rov qab los. Feem ntau, kev txhim kho tau sau tseg rau hnub plaub ntawm kev kho mob, uas yog raws li kev siv Trimetazidine-Biokom MV. Cov lus qhia rau kev siv, tus nqi qhia tau hais tias cov tshuaj tsis yog tsuas yog pheej yig xwb, tab sis kuj muaj txiaj ntsig zoo, ntxiv rau, nws muaj qhov tsawg kawg nkaus ntawm qhov tshwm sim tsis zoo uas feem ntau tsis tsim. Cov tsos mob tshwm sim tau pom muaj tsawg zaus.
Yog li, peb tau muab cov ntaub ntawv qhia ntxaws txog cov tshuaj "Trimetazidine-Biokom MV". Analogues, nqe, lus qhia, tshuaj xyuas cov tshuaj tam sim no paub rau koj. Cov tshuaj yuav tsum tau muab los ntawm tus kws kho mob tshwj xeeb thiab siv nyob rau hauv ntau npaum li cas los ntawm nws. Qhov yuav tsum tau hloov cov tshuaj kuj yog txiav txim los ntawm tus kws kho mob raws li ntau yam. Ua rawsntawm tag nrho cov lus pom zoo tso cai rau koj los kho qhov zoo tshaj plaws yam tsis muaj kev phom sij rau kev noj qab haus huv.
