"Propranolol" yog ib hom tshuaj uas muaj nyob rau hauv pab pawg ntawm cov blockers xaiv. Cov tshuaj muaj antianginal ua, antiarrhythmic thiab hypotensive. Cov tshuaj yog muab rau kev kho mob ntawm cov hlab ntsha, thyrotoxicosis, kub siab. Cov tshuaj muaj txiaj ntsig zoo rau neurocirculatory dystonia, migraine. Nws yog siv nyob rau hauv kev siv ntawm kev kho mob rau lub plawv tsis ua hauj lwm, angina pectoris. Cov tshuaj pab lub cev hauv myocardial infarction. Lawv kho nrog arrhythmia thiab hypertrophic cardiomyopathy. Thaum "Propranolol" tsis haum rau tus neeg mob, cov tshuaj analogues raug txiav txim siab los ntawm tus kws kho mob tshwj xeeb, cov tshuaj tau sau tseg uas zoo rau tus neeg mob.
Ib daim foos
Koj tuaj yeem yuav ob hom tshuaj - tshuaj "Propranolol" thiab tshuaj "Propranolol Nycomed". Cov no yog tib cov tshuaj uas tsim los ntawm cov tuam txhab sib txawv hauv cov ntsiav tshuaj.
Cov khoom xyaw tshuaj
Cov tshuaj yog tsim los ntawm cov tshuaj nquag propranolol. Cov koob tshuaj ntawm cov khoom tseem ceeb tuaj yeem sib txawv - 10,40, 80, 160 mg ib ntsiav tshuaj.
Cov khoom xyaw hauv kev tsim cov ntsiav tshuaj sib txawv thiab nyob ntawm cov chaw tsim khoom. Kom paub meej tias cov tshuaj muaj dab tsi, koj yuav tsum nyeem cov lus qhia ua ntej siv.
Kev kho mob ntawm cov tshuaj
Qhia lub peev xwm los thaiv beta-adrenergic receptors txhais tau tias "Propranolol" cov lus qhia rau kev siv. Analogues muaj cov nyhuv zoo sib xws rau lub cev. Cov ntsiav tshuaj cuam tshuam rau vascular phab ntsa receptors beta 1 thiab 2. Ib qho inhibitory nyhuv ntawm cov receptors no ua rau so ntawm cov phab ntsa ntawm cov hlab ntsha, uas tshem tawm ntau yam teeb meem - ntshav siab, nce siab xav tau oxygen, cov khoom noj tsis zoo thiab cov pa oxygen rau. cov ntaub so ntswg thiab lub cev.
Cov nyhuv antiarrhythmic ntawm cov tshuaj pab txhawb rau qhov zoo ntawm cov kev hloov pauv hauv lub cev, xws li normalization ntawm automatism ntawm lub qhov txhab, qhov txo qis hauv cov conductivity ntawm atrioventricular node, tshem tawm ntawm kev nce excitability ntawm cov hlwb uas ua rau myocardium. Ua tsaug rau Propranolol, lub plawv ua haujlwm ib txwm rov qab los, tsis muaj qhov cuam tshuam rau sab nraud stimuli uas tuaj yeem cuam tshuam tsis zoo rau nws cov atherosclerosis.
"Propranolol", analogues pab txhawb kev txhim kho ntawm cov nyhuv antianginal, uas tau tshwm sim los ntawm kev txhim kho ntawm cov leeg hauv lub plawv, txo qis ntawm cov pa oxygen tsim nyog rau nws txoj haujlwm. Qhov no txhais tau hais tias lub plawv xav tau cov pa oxygen tsawg dua rau kev cog lus, thiab qhov zaus ntawm cov contractions no heev.poob.
Hypotensive kev txiav txim yog ua raws li kev nce lumen ntawm cov hlab ntsha thiab so lawv cov phab ntsa. Kev siv ib koob tshuaj ntawm cov ntsiav tshuaj ua rau txo qis hauv cov ntshav siab, cov nyhuv tau ntev li 20 teev, txog ib hnub. Cov nyhuv hypotensive tsis tu ncua tau sau tseg tom qab ob lub lis piam ntawm kev siv cov ntsiav tshuaj. Cov tshuaj tsis haum rau kev kho mob ntawm cov xwm txheej nrog lub siab nce siab, nws tau qhia rau kev kho mob mus ntev rau kev kub siab.
Kev siv tshuaj ntev ntev ua rau kev txhim kho ntawm cov nyhuv cardioprotective. Lawv qhia txog qhov txo qis ntawm qhov yuav tshwm sim ntawm myocardial infarction tom qab kev kho mob nrog Propranolol tshuaj xyuas, cov lus qhia. Txoj kev pheej hmoo ntawm kev tuag tam sim no kuj txo qis. Nws paub tias cov tshuaj muaj txiaj ntsig zoo rau kev nce siab hauv lub cev.
YPharmacokinetics
Tom qab noj, qhov tseem ceeb ntawm cov tshuaj yog absorbed (kwv yees li 90%), thaum lub bioavailability Performance index tsis tseem ceeb. Kev sib txuas lus nrog cov proteins sib raug rau 93%. Los ntawm lub cev, cov tshuaj raug tshem tawm nrog cov zis, uas nkag mus rau hauv metabolites. Tsis muaj ntau tshaj li ib feem pua ntawm cov tshuaj muaj ib daim ntawv hloov tsis tau.
Kev qhia
"Propranolol", analogues ntawm cov lus qhia tso cai rau koj los sau npe rau kev kho mob ntawm qee yam mob thiab kab mob. Lawv raug kho nrog portal thiab arterial hypertension, myocardial dystrophy, thyrotoxicosis. Cov tshuaj pab kom txo tau qhov mob nrog rau qhov nqaim lumen ntawm aorta,qhov tseem ceeb tremor, panic tawm tsam, yuav siv tau raws li ib tug prophylactic rau migraine. Cov ntsiav tshuaj tsim nyog rau kev kho mob nrog neurocircular dystonia, myocardial infarction, extrasystole. Cov tshuaj yog muab rau cov neeg mob uas muaj mitral valve prolapse. Indications muaj xws li supraventricular tachycardia thiab sinus. Lub hom phiaj ntawm cov tshuaj yog tsim los ntawm kev tshem tawm cov tsos mob, angina pectoris, akathisia tshwm sim los ntawm kev siv cov neuroleptics. Cov tshuaj yog muab rau cov neeg mob uas muaj pheochromocytoma rau txoj kev kho mob. Cov tshuaj no yog siv los ua kom tsis muaj zog ntawm kev ua haujlwm, tom qab pib lub cev tsis muaj zog kom tshem tawm nws cov tsos mob tsis zoo.
YContraindications
Muaj qee qhov contraindications rau Propranolol. Analogues tuaj yeem xaiv tau yog tias cov tshuaj no tsis haum. Contraindications suav nrog:
- tsis nkag siab ntawm cov khoom ntawm cov khoom;
- kev poob siab cardiogenic;
- bradycardia, uas tus naj npawb ntawm lub plawv dhia ib feeb yog 55 bpm;
- metabolic acidosis;
- mob plawv lossis mob plawv tsis ua hauj lwm;
- Yvasomotor rhinitis;
- sinoatrial blockade, atrioventricular (2nd, 3rd degree);
- Prinzmetal's angina;
- ntshav siab;
- Kev siv cov tshuaj insulin;
- syndrome nrog rau qhov tsis muaj zog ntawm qhov sinus node;
- muaj ib lub sijhawm uas muaj kev nrawm nrawm;
- teeb meem ncig ncig(theem ntawm decompensation);
- cov kab mob qhia yav dhau los uas cuam tshuam rau txoj hlab pa, hawb pob, muaj bronchospasm.
Tseem muaj cov xwm txheej uas yuav tsum tau ceev faj. Hauv cov xwm txheej hauv qab no, koj tuaj yeem xaiv es tsis txhob siv tshuaj "Propranolol" analogues, cov ntsiab lus:
- myasthenia gravis;
- mob ntshav qab zib mellitus (theem ntawm decompensation, subcompensation);
- poob ntawm lub plawv cov leeg (decompensated), siab, raum;
- pastic colitis;
- xeev kev nyuaj siab;
- atrioventricular thaiv (thawj degree);
- psoriasis;
- nce thyroid ua haujlwm;
- chronic bronchitis;
- ntshav qab zib tsawg;
- emphysema;
- laus;
- cev xeeb tub, pub niam mis.
Tshuaj kho mob
Cov neeg mob ntshav siab yuav tsum noj tshuaj ob zaug ib hnub twg ntawm koob tshuaj 40 mg ib zaug. Nws qhov kev nce ntxiv yog ua tau hauv 14-28 hnub. Yog tias tsim nyog, koj tuaj yeem haus cov ntsiav tshuaj txhua hnub ntawm qhov koob tshuaj ntawm 80 txog 160 mg. Qhov zaus ntawm kev txais nyiaj yog tib yam.
Nrog tachyarrhythmia, cov neeg mob laus haus peb lossis plaub zaug ib hnub ntawm 10 mus rau 30 mg rau txhua koob tshuaj Propranolol. Analogues tuaj yeem siv yog tias cov tshuaj no tsis haum. Cov neeg mob me me uas muaj teeb meem tib yam tau muab tshuaj rau ib qho ntawm 0.2 mus rau 0.4 mg ib kilogram ntawm qhov hnyav. Ntau zausdaim ntawv thov kev kho mob - kuj peb mus rau plaub zaug ib hnub twg.
Rau lub hom phiaj tiv thaiv, cov neeg mob uas tau kuaj mob angina pectoris raug tshuaj plaub zaug ntawm cov tshuaj no txhua hnub. Ib koob tshuaj yog 20 mg. Nws qhov kev nce ntxiv yog ua tau rau xya hnub. 40 mg ntawm cov tshuaj yog noj nrog tib zaus, 80 mg - tsawg zaus (ob zaug).
Tom qab myocardial infarction, yuav tsum tau tiv thaiv. Nws tuaj yeem ua tiav nrog Propranolol. Qhov loj ntawm ib koob tshuaj yog 40 mg, cov tshuaj yuav tsum tau noj peb zaug ib hnub twg. Ua kom cov koob tshuaj ntau tshaj 80 mg.
Rau migraine, nws yog ib qho tsim nyog yuav tsum tau tiv thaiv kev siv tshuaj 40 mg ob zaug ib hnub. Yuav tsum tau nce koob tshuaj rau 80 mg, tej zaum yuav muaj ob lossis peb yam tshuaj ib hnub, thiab hauv cov menyuam peb lossis plaub. Kev suav cov koob tshuaj rau cov neeg mob me yog ua raws li qhov hnyav, rau txhua kilogram - los ntawm 1.5 txog 2 mg.
Thyrotoxicosis yog ib yam kab mob uas tau muab tshuaj los ntawm 10 mg, tab sis tsis pub ntau tshaj 40 yuav tsum tau noj peb lossis plaub zaug hauv ib hnub.
Yog tias nws tau npaj los ua pheochromocytoma therapy, cov tshuaj tau ua ke nrog alpha-blockers.
Side effects
Koj yuav tsum tau ua tib zoo saib xyuas qhov kev txiav txim siab ntawm cov tshuaj "Propranolol" cov lus qhia rau kev siv. Analogues, tshuaj xyuas kuj tsis tshua muaj cov ntaub ntawv tseem ceeb uas cuam tshuam rau kev xaiv cov tshuaj rau kev kho mob. Txhawm rau txo qhov kev pheej hmoo ntawm kev tsim cov tshuaj tiv thaiv tsis zoo ntawm lub cev, nws yog qhov yuav tsum tau ua tib zoo saib xyuasnyeem cov lus qhia, nws yuav muaj txiaj ntsig los nyeem cov kev tshuaj xyuas.
Cov tshuaj, yog tias siv tsis raug, tuaj yeem ua mob rau cov hlab plawv, ua rau muaj kev cuam tshuam hauv nruab nrab paj hlwb, kab mob endocrine. Cov tsos mob tsis zoo los ntawm lub plab zom mov yog ua tau, qhov xwm txheej ntawm cov mucous daim nyias nyias thiab daim tawv nqaij yuav cuam tshuam. Ntawm cov kev mob tshwm sim uas tau teev tseg hauv cov lus qhia yog teeb meem nrog kev ua pa. Lwm yam kev mob tshwm sim kuj tshwm sim.
Analogues, nqe
Ua ntej yuav cov tshuaj "Propranolol", analogues, tus nqi feem ntau tau kawm los ntawm cov neeg mob. Koj tuaj yeem yuav tshuaj rau 16-75 rubles. Tus nqi yog txiav txim los ntawm tus naj npawb ntawm cov ntsiav tshuaj hauv pob. Koj tuaj yeem hloov cov tshuaj nrog Propranobene, Obzidan lossis Anaprilin tshuaj. Koj tuaj yeem kho nrog Inderal LA, Inderal.
Thaum koj paub txog cov tshuaj "Propranolol" cov lus qhia rau kev siv, nqe, analogues muab cov ntaub ntawv tseem ceeb uas tso cai rau koj txiav txim siab qhov tseeb tshaj plaws thaum xaiv cov tshuaj thiab txoj kev kho mob.
Reviews
Kev tshuaj xyuas feem ntau yog qhov zoo. Lawv tshaj tawm tias kev kho tshuaj feem ntau siv tau zoo. Tsis tas li ntawd, ntau tus txaus siab rau tus nqi qis ntawm cov tshuaj. "Propranolol" tswj kom tswj cov ntshav siab nyob rau theem ib txwm, sai sai tshem tawm ntawm palpitations. Cov tshuaj txo cov kev tshwm sim ntawm cov kab mob plawv, relieves ib tug neeg los ntawm excitement. Cov tib neeg feem ntau tawm kev tshuaj xyuas tsis zoo vim muaj kev phiv loj heev uas tuaj yeem tshwm sim thaum kho. Qee zaumqaug zog heev, teeb meem pw tsaug zog, npau suav phem tshwm sim.
