Nadroparin Calcium tsim nyob rau hauv daim ntawv twg? Daim ntawv tso tawm ntawm cov tshuaj no tau nthuav tawm hauv kab lus no. Nws kuj muaj cov ntaub ntawv hais txog cov yam ntxwv ntawm cov tshuaj hais, nws cov lus qhia thiab cov kev mob tshwm sim.
Form, composition
"Nadroparin Calcium" - cov tshuaj npaj rau kev txhaj tshuaj hauv qab daim tawv nqaij. Cov tshuaj nyob rau hauv nqe lus nug yog ib tug ntshiab, lub teeb daj los yog tsis muaj xim, me ntsis opalescent tshuaj kua. Nws active tivthaiv yog cov khoom ntawm tib lub npe - calcium nadroparin. Tsis tas li ntawd, muaj pes tsawg leeg ntawm cov tshuaj no suav nrog cov khoom xyaw ntxiv hauv qab no: dej rau kev txhaj tshuaj, calcium hydroxide tov lossis hydrochloric acid (diluted).
Nadroparin Calcium yog muag hauv cov koob txhaj tshuaj ib zaug, uas tau ntim rau hauv cov hlwv thiab pob ntawv.
Drug properties
"Nadroparin Calcium" yog cov tshuaj tiv thaiv kab mob thiab tshuaj tiv thaiv kab mob. Raws li cov lus qhia, cov tshuaj no yog ib qho hnyav molecular heparin, uas tau tsim los ntawm tus qauv heparin los ntawm depolymerization. Nws muaj affinity siab rau cov ntshav protein antithrombin 3 thiab suppresses yam Xa zoo.
Nws tsis tuaj yeem hais tias tusCov tshuaj hloov cov rheological tsis nyob rau hauv cov ntshav, uas yog, txo nws viscosity, tsub kom lub permeability ntawm daim nyias nyias ntawm granulocyte hlwb thiab platelets, thiab kuj tiv thaiv kev loj hlob ntawm xws li ib tug pathological txheej txheem raws li vascular occlusion.
Piv rau unfractionated heparin, cov tshuaj no muaj qhov tsis muaj zog ntawm platelet kev ua, thawj hemostasis thiab aggregation.
Kinetics ntawm cov khoom
Lub peev xwm kinetic ntawm Nadroparin Calcium yog dab tsi? Tom qab kev tswj hwm subcutaneous, qhov zoo tshaj plaws anti-Xa kev ua ntawm tus neeg sawv cev no tau pom tom qab 5 teev. Ntxiv mus, nws ib nrab-lub neej yog 2 teev. Cov tshuaj no yog metabolized hauv daim siab los ntawm depolymerization thiab desulfation.
xov tshuaj
Cov hlab ntsha tuaj yeem tshwm sim rau ntau yam. Txhawm rau tiv thaiv kev txhim kho ntawm cov txheej txheem pathological thiab txaus ntshai heev, ntau tus kws kho mob tau sau cov tshuaj Fraxiparin rau lawv cov neeg mob, cov khoom tseem ceeb ntawm calcium nadroparin. Yog li, cov cuab yeej hais tau qhia rau kev siv:
- hauv kev kho mob thromboembolism;
- rau kev tiv thaiv ntawm cov teeb meem thromboembolic (piv txwv li, thaum lub sij hawm orthopedic thiab phais, hauv cov neeg uas muaj kev pheej hmoo ntawm thrombosis, nrog rau cov mob (mob) lub plawv los yog ua tsis taus pa);
- hauv kev kho mob myocardial infarction thiab tsis ruaj khov angina;
- rau kev tiv thaivntshav khov
txwv tsis pub teem caij
Clogging ntawm cov hlab ntsha yog qhov tshwm sim txaus ntshai heev. Txawm li cas los xij, txawm tias muaj tus mob no, cov tshuaj "Fraksiparin" tsis yog ib txwm muab rau cov neeg mob. Raws li cov kws tshaj lij, cov tshuaj no muaj cov hauv qab no contraindications:
- intracranial hemorrhage;
- thrombocytopenia thaum siv nadroparin;
- kab mob ntawm cov kabmob hauv nruab nrog cev uas nyiam los ntshav;
- cov tsos mob lossis kev pheej hmoo siab los ntshav cuam tshuam nrog kev ua tsis taus hemostasis;
- kev cuam tshuam kev phais thiab kev raug mob ntawm lub hlwb, qaum qaum, thiab lub cev tsis pom kev;
- mob septic endocarditis;
- hnub nyoog yau;
- mob raum tsis ua haujlwm;
- siab rhiab heev rau nadroparin.
siv ceev faj
Nrog ceev faj, Fraxiparine tsuas yog raug tshuaj rau hauv cov xwm txheej cuam tshuam nrog kev pheej hmoo los ntshav, suav nrog:
- raum tsis ua haujlwm;
- mob ntshav siab ntshav siab;
- nyob rau lub sijhawm tom qab;
- siab tsis ua hauj lwm;
- hauv cov neeg hnyav dua 40 kg;
- peptic ulcers;
- mob ntshav qab zib hauv retina lossis choroid;
- ua ke nrog tshuaj uas ua rau muaj kev pheej hmoo los ntshav.
Tshuaj "Nadroparin Calcium": cov lus qhia rau kev siv
Raws li cov lus qhia, tus neeg sawv cev nug yuav tsumtxhaj tshuaj subcutaneously rau hauv lub plab (hloov mus rau sab laug thiab sab xis). Hauv qhov no, tus neeg mob yuav tsum nyob rau hauv lub supine txoj hauj lwm. Nws tseem tso cai rau txhaj rau hauv tus ncej puab.
Cov koob tshuaj no tsuas yog xaiv los ntawm tus kws kho mob xwb, nyob ntawm qhov muaj qhia tau. Piv txwv li, txhawm rau tiv thaiv thromboembolism hauv kev phais mob, ib koob tshuaj Fraxiparine sib npaug rau 0.3 ml yog siv. Hauv qhov no, cov tshuaj tau muab 4 teev ua ntej qhov kev npaj ua haujlwm, thiab tom qab ntawd - ib zaug ib hnub.
Lub sijhawm ntawm kev kho mob nrog cov tshuaj no kuj nyob ntawm tus kab mob uas twb muaj lawm (feem ntau yog 6 hnub).
Side Effects
Kev siv cov tshuaj hauv nqe lus nug tuaj yeem ua rau muaj qhov tsis zoo, tshwj xeeb:
- ntshav ntawm ntau qhov chaw;
- nce hauv siab enzymes;
- thrombocytopenia thiab eosinophilia;
- hypersensitivity tshua;
- cov tshuaj tiv thaiv hauv zos xws li qhov pom ntawm subcutaneous hematoma ntawm qhov chaw txhaj tshuaj, tsim cov pob tawv tawv uas ploj tom qab ob peb hnub, necrosis ntawm daim tawv nqaij hauv qhov chaw txhaj tshuaj;
- hyperkalemia thiab priapism.
Reviews
Cov hlab ntsha tuaj yeem tshwm sim rau leej twg. Yog li ntawd, cov neeg uas muaj ntshav khiav tsis zoo feem ntau tau muab tshuaj Fraxiparin los yog hu ua Nadroparin Calcium. Cov neeg mob hais tias qhov kev kho no ua tau zoo nrog nws txoj haujlwm ncaj qha. Txawm li cas los xij, nws yuav tsum raug sau tseg tias cov tshuaj no feem ntau ua rau muaj kev cuam tshuam tsis zoo. Hauv qhov noCov kws tshaj lij pom zoo kom hloov nws nrog tshuaj muaj kev nyab xeeb dua.
