Arterial hypertension yog qhov mob ntawm cov neeg niaj hnub hauv ntiaj teb. Ntau yam tsis zoo sab nraud, ecology tsis zoo, kev ntxhov siab tas li, tsis zoo thiab khoom noj khoom haus tsis tu ncua tsim cov xwm txheej ua ntej rau kev txhim kho cov kab mob plawv thiab qhov tshwm sim ntawm tus kab mob no.
Lub tsev muag tshuaj niaj hnub nrhiav los tsim cov tshuaj uas, yog tias lawv tsis kho tus neeg mob ntshav siab, ces tsawg kawg ua kom ntshav siab tswj tau, yog li txo qis kev pheej hmoo ntawm kev tsim myocardial infarctions thiab strokes.
Tam sim no, cov tshuaj tiv thaiv kab mob siab xws li Hartil, analogues ntawm cov tshuaj no, uas tau tsim ntau heev, yog cov neeg siv khoom xav tau ntau.
Khartil
Lub chaw tsim tshuaj "Hartil" yog lub tuam txhab Hungarian EGIS Pharmaceuticals PLC. Cov neeg siv khoom tau nthuav tawm peb hom tshuaj no: Hartil, Hartil D thiab Hartil Amlo.
Cov khoom xyaw tseem ceeb ntawm "Hartil" yog cov tshuaj ramipril. Cov lus qhia tseem ceeb rau kev siv cov tshuaj no yog muaj nyob rau hauv ib tus neeg ntawm cov kab mob xws li arterial hypertension, ntshav qab zib nephropathy, diffuse raum kab mob ntawm qhov xwm txheej. Tsis tas li ntawd, "Hartil" cov lus qhia rau kev siv (feem ntau cov analogues kuj tseem yuav ua rau muaj txiaj ntsig zoo) pom zoo kom siv los txo qis qhov tshwm sim ntawm kev txhim kho myocardial infarction, "coronary death", strokes rau cov neeg uas muaj kab mob plawv (mob plawv ischemic). Nws kuj tseem siv tau los sau "Hartil" rau cov neeg uas raug kev txom nyem los ntawm kev mob plawv tsis txaus nyob rau hauv nws lub sijhawm ntev thiab txhim kho tom qab tus neeg mob tau raug mob myocardial infarction (yuav tsum tau siv ua ntej siv "Hartil" - ruaj khov hemodynamic tsis tau).
Cov tshuaj "Khartil D" (analogues rau cov teebmeem muaj) muaj ob yam khoom xyaw - ramipril thiab hydrochlorothiazide. Thawj cov tshuaj txo cov ntshav siab, yog li txo cov load ntawm lub plawv. Cov tshuaj thib ob yog cov tshuaj diuretic uas txhawb nqa cov txheej txheem ntawm kev tshem tawm cov ntsev thiab dej los ntawm lub raum, thiab, zoo li ramipril, txo cov ntshav siab. Yog li, Hartil D tau muab tshuaj rau kev kho mob ntshav siab nyob rau hauv cov xwm txheej uas kev kho mob nyuaj nrog ACE inhibitors thiab diuretics tau qhia.
Cov tshuaj tiv thaiv kab mob siab "Hartil Amlo" (analogues hauv cov ntsiab lus thiab cov nyhuv yog tsim los ntawm lub tsev muag tshuaj niaj hnub) muaj ob yam tseem ceeb - ramipril thiab amlodipine. Kev teem caij ntawm cov tshuaj no yog siv rau kev kho mob ntawm arterial hypertension nyob rau hauv cov neeg mob nyob rau hauv uas lub parallel tswj ntawm ramipril thiab amlodipine muaj cov txiaj ntsig zoo ntawm tus kheej thiab ua ke.
Ramipril-C3
Cov tshuaj "Ramipril-C3" yog ib qho analogue ntawm "Khartil" ntawm Lavxias teb sab ntau lawm. Ua nyob rau hauv Moscow los ntawm lub tuam txhab "Northern Star". Lub ntsiab active ingredient yog ramipril. Cov excipients yog magnesium stearate thiab lactose monohydrate.
Cov tshuaj yog muab rau cov neeg uas muaj kev kuaj mob xws li arterial hypertension, plawv tsis ua hauj lwm (hloov daim ntawv thiab tsim tom qab mob myocardial infarction).
Hauv cov kab mob zoo li no, qhov yuav tsum tau ua ua ntej rau kev teem caij ntawm "Ramiplila-C3" yog qhov ruaj khov hemodynamic tsis. Tsis tas li qhov qhia txog kev noj cov tshuaj analogue ntawm Hartil ntsiav tshuaj yog qhov muaj ntshav qab zib thiab tsis yog ntshav qab zib nephropathy hauv tus neeg mob. Nrog rau qhov kev xav tau zoo, "Ramipril-C3" tau muab rau cov tib neeg tom qab kev phais mob rau transluminal coronary angioplasty thiab coronary artery bypass grafting (yog tias tus neeg mob qhov chaw kho mob ruaj khov).
Raws li contraindications rau noj cov tshuaj no yog ib tug neeg hypersensitivity rau lub ntsiab los yog auxiliary Cheebtsam ntawm cov tshuaj, ib tug keeb kwm ntawm cov ntaub ntawv hais txog yav tas los pauv angioedema, provoked los ntawm ACE inhibitor tshuaj. Ramipril-C3 yog contraindicated nyob rau hauv cov neeg mob uas tsis tau mus txog18 xyoo, vim tsis muaj ntaub ntawv hais txog nws txoj kev nyab xeeb thiab kev ua tau zoo.
Dilarel
Cov tshuaj tiv thaiv kab mob siab "Dilaprel" tau nthuav tawm hauv khw muag tshuaj raws li Lavxias analogue ntawm "Khartil". Lub ntsiab active ingredient yog ramipril. Cov pab cuam yog calcium stearate thiab colloidal silicon dioxide.
Cov lus qhia rau kev siv cov tshuaj no: cov neeg mob uas muaj kab mob xws li kub siab tseem ceeb, mob plawv tsis ua hauj lwm (ua ke nrog lwm cov tshuaj, tshwj xeeb tshaj yog diuretics).
Kev coj ua ntawm kev sau tshuaj rau nephropathy (mob ntshav qab zib, tsis muaj ntshav qab zib), suav nrog thaum ua ke nrog proteinuria, ntshav siab. Kev tshuaj xyuas kom tau txais "Dilaprel" thiab nyob rau hauv rooj plaub uas ob peb hnub (2-9 hnub) tom qab mob myocardial infarction ua rau lub plawv tsis ua haujlwm.
Cov tshuaj muab cov txiaj ntsig zoo rau cov neeg mob uas nws qhov kev noj qab haus huv yog tus cwj pwm los ntawm kev pheej hmoo siab plawv (kev loj hlob sai ntawm myocardial infarction, mob stroke).
Yog vim li cas tsis sau cov tshuaj no ("Hartil" yog tus yam ntxwv los ntawm yuav luag tib yam contraindications) suav tias yog keeb kwm ntawm angioedema, hemodynamically tseem ceeb stenosis ntawm lub raum cov hlab ntsha, stenosis ntawm aortic los yog mitral li qub, arterial hypotension. (tsis tshua muaj ntshav siab), lub raum tsis txaus thiab xav tau hemodialysis, Dilaprel tsis raug tso cai los ntawm cov neeg mob nroginsufficiency ntawm lub plawv ua hauj lwm nyob rau hauv ib tug ntev daim ntawv nyob rau hauv lub theem ntawm decompensation thiab nyob rau hauv lub xub ntiag ntawm nephropathy. Nyob rau theem mob ntawm lub plawv nres, cov tshuaj tsis raug tshuaj rau qhov tsis ruaj khov angina pectoris, cor pulmonale, thiab rau qhov mob ventricular arrhythmias.
Vazolong
Cov tshuaj analogue no ("Hartil" muaj tib lub ntsiab tseem ceeb - ramipril) muaj cov lus qhia hauv qab no rau kev siv: kub siab (arterial, refractory, malignant, vasorenal), nephropathy (mob ntshav qab zib thiab kev loj hlob ntawm keeb kwm ntawm lub raum tsis zoo. kab mob).
Muaj cov nyhuv cardioprotective thiab txo cov platelet aggregation. Cov tshuaj tsub kom qhov rhiab heev ntawm cov ntaub so ntswg rau insulin. Cov nyhuv hypotensive yog hnov ib thiab ib nrab teev tom qab noj cov tshuaj, qhov siab tshaj plaws tau ua tiav tom qab 5-9 teev, lub sij hawm raug mus txog 24 teev.
Los ntawm lub ntsiab contraindications rau kev siv cov tshuaj no, ib tug muaj peev xwm paub qhov txawv hypersensitivity rau lub Cheebtsam (lub ntsiab thiab pab) ntawm cov tshuaj los yog rau lwm yam ACE inhibitors, muaj nyob rau hauv lub anamnesis ntawm cov ntaub ntawv hais txog yav tas los pauv angioedema, provoked los ntawm kev kho mob nrog ACE inhibitors.
Thaum cev xeeb tub, nws yog contraindicated los noj cov tshuaj no, nrog rau Hartil. Cov lus qhia rau kev siv, tshuaj xyuas (analogues ntawm "Khartil", uas muaj ramipril, tsis tuaj yeem muab tshuaj rau cov poj niam cev xeeb tub), cov neeg ua haujlwm noj qab haus huv tau pom zoo kom paub tseeb tias tsis muaj cev xeeb tub ua ntej pib kho. Yog tias tus neeg mob cev xeeb tub thaum kho, cov tshuaj nrog ramipril yuav tsum tau txiav tam sim ntawd thiab lwm txoj kev kho yuav tsum raug xaiv.
Amprilan
Amprilan, ib qho ACE inhibitor, kuj yog ib qho analogue ntawm Hartil, ob qho tib si nyob rau hauv muaj pes tsawg leeg thiab hais txog nws cov nyhuv. Lub ntsiab active ingredient ntawm cov tshuaj yog ramipril. Cov khoom pabcuam yog sodium bicarbonate, lactose monohydrate, croscarmellose sodium, starch.
Cov lus qhia rau kev teem sijhawm ntawm cov tshuaj no feem ntau yuav luag zoo ib yam li yav dhau los tau piav qhia "Vazolong", "Dilaprelu", Ramipril-C3 ": kub siab, mob plawv tsis ua haujlwm, nephropathy, txo qis hauv kev pheej hmoo ntawm kev mob plawv. pathology
Daim ntawv teev cov contraindications rau kev siv cov tshuaj no yog qhov dav heev. "Amprilan" tsis tau muab tshuaj rau cov neeg mob uas muaj cov kab mob loj xws li ob lub raum hlab ntsha stenosis nyob rau hauv daim ntawv tseem ceeb hemodynamically thiab stenosis ntawm cov hlab ntsha ntawm ib lub raum, lub raum tsis txaus, mob tom qab hloov lub raum thiab hemodialysis. Cov tshuaj yuav tsum tsis txhob siv rau cov neeg mob uas muaj teeb meem hauv plawv: aortic thiab / lossis mitral stenosis, mob plawv tsis ua hauj lwm (theem decompensation), obstructive cardiomyopathy thiab arterial hypertension.
Nws tsis tsim nyog rau cov poj niam noj tshuaj thaum lub sijhawm xeeb tub thiab pub niam mis. Contraindication yog hnub nyoog qis dua 18 xyooxyoo.
Ramicardia
Analogues ntawm cov tshuaj "Hartil" yog tam sim no nruj heev saturated lub khw muag tshuaj. Lwm lub npe nrov analogue yog Ramicardia. Indications thiab contraindications rau cov tshuaj yuav luag tib yam li cov yav tas los suav hais tias "Amprilan".
Ua ntej pib kho cov tshuaj no, cov kws tshaj lij pom zoo kom kuaj xyuas lub raum mob, vim tias nyob ntawm lub xeev ntawm cov kabmob no, xaiv ib tus neeg txhaj tshuaj rau kev kho mob (lossis cov tshuaj raug tso tseg tag nrho). Nyob rau hauv tus txheej txheem ntawm kev kho mob nrog cov tshuaj no, uas yuav luag zoo tib yam rau cov tshuaj Hartil, cov lus qhia rau kev siv (analogues, yuav luag tag nrho cov, yuav ua rau mob loj heev rau lub raum) pom zoo saib xyuas cov kev mob ntawm cov zis, electrolyte muaj pes tsawg leeg ntawm cov ntshav., tus nqi ntawm lub raum enzymes thiab daim duab ntawm cov ntshav peripheral.
Cov neeg mob uas muaj cov kua dej tsis txaus, sodium, ua ntej pib noj "Ramicardia", nws yog ib qho tsim nyog yuav tsum tshem tawm tag nrho cov dej thiab electrolyte txawv txav. Thaum kho nrog cov tshuaj no, nws tsis tuaj yeem ua tiav hemodialysis siv polyacrylonitrile daim nyias nyias, vim. muaj kev pheej hmoo ntawm kev tsim cov tshuaj tiv thaiv anaphylactic.
Ramigamma
Analogues ntawm "Khartil" yog dav siv nyob rau hauv Russia. Lwm cov tshuaj no hu ua "Ramigamma". Lub ntsiab active ingredient yog ramipril. Indications thiab contraindications yog zoo ib yam li cov piav saum toj no. Kev kho mob nrog cov tshuaj no yuav tsum nyob rau hauv kev saib xyuas ntawm tus kws kho mob.
Tom qab thawj koob tshuaj "Ramigamma" tau noj, lossis cov tshuaj diuretic tau txais los ntawm tus neeg mob tau nce ntxiv, ntshav siab yuav tsum tau ntsuas ntau li ntau tau hauv 8 teev tom ntej. Qhov no yog qhov tsim nyog txhawm rau txhawm rau tiv thaiv kev txhim kho ntawm cov tshuaj tiv thaiv tsis muaj zog thiab nrawm nrawm (poob ntshav siab). Cov neeg mob uas muaj kab mob loj ntawm lub raum thiab cov hlab plawv yuav tsum tau ua tib zoo saib xyuas.
Nyob rau hauv cov txheej txheem ntawm kev kho mob, nws yog ib qho tsim nyog los tswj cov qib ntawm leukocytes kom tsis txhob nco lub sijhawm ntawm kev loj hlob ntawm leukopenia.
"Hartil", analogues ntawm cov tshuaj no (xws li "Remigamma") yuav tsum tsis txhob muab rau cov neeg mob uas tam sim no tau txais kev kho mob desensitizing (kom txo tau qhov tshwm sim tsis haum rau kab tom). Kev siv ACE inhibitors thiab sensitizers tuaj yeem ua rau muaj kev phom sij rau lub neej tsis zoo ntawm lub cev (ua pa tsis ua haujlwm, poob ntshav siab, ntuav, thiab lwm yam)
Cardipril
Txawm tias ib qho tshuaj zoo-paub - ib qho analogue ntawm "Hartil" - "Kardipril". Cov khoom xyaw nquag yog ramipril. Cov lus qhia tseem ceeb rau kev siv cov tshuaj no yog kub siab, mob plawv tsis ua hauj lwm (raws li ib feem ntawm txoj kev kho mob), nephropathy (nrog rau nws cov theem pib), mob plawv tsis txaus tom qab myocardial infarction.
Contraindications rau kev siv "Cardipril" yog qhov dav heev. Cov tshuaj yuav tsum tsis txhob muab rauLub xub ntiag ntawm lub raum thiab lub siab tsis txaus, nrog rau cov kab mob lupus erythematosus, stenosis ntawm lub raum cov hlab ntsha, nrog hyperkalemia thiab hyponatremia, nrog kev tsim txom ntawm pob txha hematopoiesis. Tsis txhob muab tshuaj thaum cev xeeb tub, lactation thiab cov neeg mob hnub nyoog qis dua 18 xyoo.
Nrog rau kev noj ntau dhau ntawm Cardipril, mob ntshav siab heev (tej ntshav siab), lub raum tsis ua haujlwm, muaj qhov txawv txav ntawm electrolyte loj, thiab kev poob siab yuav tshwm sim. Txhawm rau tshem tawm qhov tshwm sim, nws yog ib qho tsim nyog yuav tsum ua raws li kev soj ntsuam tas li thiab kev txhawb nqa tom ntej ntawm lub luag haujlwm tseem ceeb ntawm lub cev. Nrog kev poob qis hauv siab, koj tuaj yeem nkag mus rau qhov ntim ntxiv ntawm sodium thiab kua dej. Hemodialysis yuav tsis muaj txiaj ntsig zoo.
Tritatse
Dab tsi ntxiv muaj qhov analogue ntawm "Khartil"? Lwm cov tshuaj uas paub dav thiab siv los ntawm cov neeg mob yog Tritace. Cov tshuaj yog tsim nyob rau hauv lub teb chaws Yelemees thiab Fabkis. Lub ntsiab active ingredient yog ramipril. Cov lus qhia rau kev siv, nrog rau contraindications, yog kwv yees li zoo ib yam li tag nrho cov yav tas los piav ACE inhibitor tshuaj. Kev kho mob nrog Tritace feem ntau yuav siv sijhawm ntev heev, lub sijhawm uas tau txiav txim siab hauv txhua kis los ntawm tus kws kho mob.
Ua ntej koj pib kho nrog cov tshuaj no, koj yuav tsum xyuas kom meej tias tsis muaj cov mob xws li hyponatremia thiab hypovolemia. Yog tias tus neeg mob tau noj cov tshuaj diuretic yav dhau los, lawv yuav tsum tau txiav tawm lossis tsawg kawg txo lawv cov tshuaj 2-3 hnub ua ntej pib kho Tritace.
Tom qab noj thawj koob lossis nce qhov ntim ntawm cov tshuaj diuretics, cov neeg ua haujlwm kho mob yuav tsum xyuas kom tus neeg mob tau ua tib zoo saib xyuas yam tsawg 8 teev. Qhov no yog qhov tsim nyog txhawm rau txhawm rau ntsuas qhov tsim nyog yog tias muaj ntshav siab sai dhau.
Yog tias tus neeg mob muaj lub plawv tsis ua haujlwm lossis mob ntshav siab, nws raug tso cai pib kho nrog Tritace nkaus xwb hauv tsev kho mob.
Lub sijhawm tag nrho ntawm kev kho mob nrog cov tshuaj no, nws yog ib qho tsim nyog los saib xyuas lub raum ua haujlwm, qib ntawm electrolyte concentration, hematological tsis (qib hemoglobin, platelet suav, leukocyte, erythrocyte suav, leukocyte formula).
Cov tswv yim ntawm ACE inhibitors
Ib yam li cov tshuaj loj, uas tuaj yeem raug ntaus nqi rau Hartil thiab nws cov analogues zoo tshaj plaws, kev tshuaj xyuas los ntawm kws kho plawv, tus kws kho mob ntawm lwm yam tshwj xeeb lossis tus neeg mob tuaj yeem tawm ob qho kev qhia zoo thiab tsis zoo.
Feem ntau cov neeg mob qhia Hartil nws tus kheej thiab feem ntau ntawm nws cov analogues ua cov tshuaj ua haujlwm sai, siv tau txawm tias ntshav siab heev. Lub sijhawm ntawm kev raug tshuaj ntawm pab pawg no kuj nce mus txog 24 teev. Txawm hais tias tus nqi ntawm cov tshuaj no hloov pauv ntau, tsis yog txhua yam tshuaj muaj nyob rau ntau tus neeg siv khoom.
Txawm li cas los xij, muaj kev xav tsis zoo txog cov tshuaj"Hartil". Analogues, kev tshuaj xyuas tus neeg mob kuj qee zaum pom los ntawm qhov tsis zoo. Yog vim li cas yog tias tag nrho cov tshuaj no tuaj yeem ua rau muaj kev loj hlob ntawm tag nrho cov kev mob tshwm sim, qee qhov mob hnyav heev. Ntawm qhov teeb meem no, cov kws kho mob tau koom nrog lawv cov neeg mob. Txawm hais tias feem coob ntawm cov kws kho mob ntseeg tias cov tshuaj no tau cawm ntau pua tus neeg thiab tib neeg xav tau lawv tiag tiag. Qhov tseem ceeb tshaj plaws yog tsis txhob sau koj tus kheej cov tshuaj ntawm qib no ntawm koj tus kheej thiab ua raws li cov lus pom zoo ntawm koj tus kws kho mob.
