Cov kua txiv plab tshwm sim los ntawm kev ua haujlwm ntawm lub plab hnyuv. Nws yog cov kua uas tsis muaj xim, tsis muaj ntxhiab tsw nrog me me ntawm cov hnoos qeev. Ib qho kev sib txawv ntawm qhov kev cai no, xws li kev hloov xim thiab qhov ntom ntom, qhia tau hais tias muaj teeb meem nrog lub plab zom mov. Cov muaj pes tsawg leeg ntawm gastric kua txiv yog complex, vim nws yog tsim los ntawm ntau lub hlwb ntawm lub plab mucosa. Nws lub ntsiab tivthaiv yog hydrochloric acid, uas, nyob rau hauv lem, muaj ib tug concentrated muaj pes tsawg leeg.
Cov kua txiv plab
Ntxiv nrog rau hydrochloric acid, kua txiv plab muaj cov khoom nram qab no
- Bicarbonates (lawv neutralize cov teebmeem ntawm hydrochloric acid ntawm phab ntsa ntawm lub plab).
- Pepsinogen, uas hloov mus rau hauv pepsin (tom kawg yog koom nrog hauv kev tawg ntawm cov protein). Pepsin tau muab faib ua lwm tsev neeg ntawm cov enzymes, txhua tus muaj nws tus kheej ua haujlwm.
- Mucus (nws kuj tiv thaiv mucosa los ntawmkev puas tsuaj).
- Castle Factor (ib qho enzyme uas pab nqus B12).
Txawm li cas los xij, lub ntsiab lus tseem ceeb ntawm cov kua txiv hmab txiv ntoo yog tseem hydrochloric acid. Nws yuav tham.
hydrochloric acid yog dab tsi?
Nws yog tsim los ntawm niam txiv cov qog ntawm lub plab, nyob ntawm lub cev thiab hauv qab ntawm lub cev. Nyob rau hauv qhov tseeb, lub mucous daim nyias nyias muab faib ua ob peb cheeb tsam: ib tug tsim hydrochloric acid, lwm yam tso tawm bicarbonates uas neutralize nws. Nws yog ib qho tseem ceeb uas cov txiv neej muaj ntau zaus niam txiv lub hlwb ntau dua li poj niam.
Cov ntsiab lus ntawm lwm cov kua qaub hauv plab yog qhov tsis txaus ntseeg. Yog li, yog tias lactic acid pom nyob rau hauv nws, qhov no qhia tau hais tias hydrochloric acid yog tsim nyob rau hauv me me (pH qis ntawm lub plab) los yog tsis ua kiag li. Cov tom kawg yuav qhia tau tias qhov ua tsis tiav loj li oncology.
Y Hydrochloric acid nyob rau hauv lub plab muaj ib tug nruj concentration theem - nws yog 0.3-0.5% (los yog 160 mmol / l). Nws muaj pes tsawg leeg yog li concentrated yog hais tias tsis muaj cov tshuaj tiv thaiv nyob rau hauv lub gastric kua txiv thiab mucous daim nyias nyias, nws yuav hlawv tawm nws lub plab. Tias yog vim li cas nrog kev tsim cov hnoos qeev los ntawm lub plab tsis txaus, ib tus neeg mob gastritis lossis duodenal rwj. Acid muaj nyob rau hauv lub plab tas li, tab sis nyob rau hauv cov lus teb rau kev noj zaub mov, nws cov nyiaj nce. Basal secretion ntawm hydrochloric acid (uas yog, sawv ntxov) yog 5-7 mmol / teev.
Lub plab noj qab haus huv tsim tau txog 2.5 litres ntawm hydrochloric acid ib hnub!
Kev zais ciahydrochloric acid muaj 3 theem.
- Reaction rau saj thiab tsw ntawm zaub mov. Nws yog launched thiab kis los ntawm lub hauv nruab nrab lub paj hlwb mus rau lub plab zom mov los ntawm cov hlab ntsha.
- Tom qab zaub mov nkag mus rau hauv lub cev, ib theem tseem ceeb pib pib. Gastrin ua rau niam txiv lub hlwb, txhawb kev tsim cov hydrochloric acid.
- theem kawg pib tom qab chyme (twb zom zaub mov) nkag mus rau hauv duodenum. Vim tias qhov nce hauv hydrochloric acid, lub plab tsim somatostatin, nws cov blocker.
Yuav ua li cas ntawm hydrochloric acid hauv plab?
Ua ntej tshaj plaws, nws txhim kho kev zom zaub mov, rhuav tshem cov kab mob feem ntau nkag mus rau hauv plab nrog zaub mov, uas ua rau qeeb lossis cuam tshuam rau cov txheej txheem putrefactive.
Lub luag haujlwm ntawm hydrochloric acid hauv plab yog dab tsi? Hauv qab no yog ib daim ntawv teev qhia txog qhov teeb meem no.
- Protein denaturation (qhov no yog kev puas tsuaj ntawm lawv cov qauv molecular) thiab lawv o.
- Ua kom pepsinogen, uas hloov mus ua pepsin, yog ib qho tseem ceeb tshaj plaws enzymes uas zom cov proteins.
- Tsim ib puag ncig acidic uas ua rau kev zom zaub mov yooj yim dua.
- Kev khiav tawm ntawm cov zaub mov ntawm lub plab mus rau duodenum qhov kev zom zaub mov txuas ntxiv.
- Kev tiv thaiv kab mob - ntau cov kab mob tsis tuaj yeem nyob hauv ib puag ncig kev ua phem.
- Kev tawm dag zog ntawm kev tso kua txiv pancreatic.
Kev saib xyuas tshwj xeeb tsim nyog rau lub luag haujlwm ntawm hydrochloric acid hauv kev tawg ntawm cov protein. Qhov tseem ceeb ntawm cov proteins hauv lub cev yog qhov loj heev. Lo lus nug no rau ntau tustau kawm los ntawm cov kws tshawb fawb tau ntau xyoo lawm. Nws tau raug tsim los hais tias hydrochloric acid nyob rau hauv lub plab nkoos zus tau tej cov pepsin, tsim ib tug haum ib puag ncig rau nws cov dej num, txhawb ib feem denaturation thiab o ntawm cov proteins. Hauv duodenum, hydrochloric acid txhawb kev tsim cov secretin, txhim kho cov hlau nqus thiab muaj cov kab mob bactericidal.
YProteins thiab gastric acidity
Lub luag haujlwm ntawm hydrochloric acid hauv kev zom cov protein tseem tsis tau meej. Txawm li cas los xij, nws tau raug tsim los hais tias nyob rau hauv cov kab mob inflammatory ntawm lub plab, nws cov secretion yog cuam tshuam thiab, vim li ntawd, kev zom cov proteins.
Qhov tseem ceeb ntawm cov protein hauv peb lub cev tsis tuaj yeem kwv yees ntau dhau. Cov pab pawg no tau muab faib ua ntau pawg, txhua tus tau koom nrog nws txoj kev lag luam. Yog li, cov tshuaj hormones tswj cov txheej txheem ntawm lub neej (kev loj hlob thiab kev yug me nyuam), enzymes proteins muab cov txheej txheem tshuaj (ua pa, plab zom mov, metabolism), hemoglobin saturates hlwb nrog oxygen.
Denaturation ntawm cov proteins (qhov no ua rau cov txheej txheem ntawm lawv cov kev sib cais tom qab) tso cai rau lub cev siv lawv cov khoom mus rau qhov siab tshaj plaws. Txhua protein yog tsim los ntawm cov amino acids. Feem ntau ntawm lawv yog synthesized los ntawm peb lub cev, tab sis muaj ib pab pawg neeg ntawm qhov tseem ceeb amino acids uas nkag mus rau lub cev tsuas yog los ntawm sab nraud.
Npaj acidity
Qhov tseem ceeb xws li pH ntawm lub plab ncaj qha nyob ntawm hydrochloric acid. Thiab yog hais tias muaj kev sib txawv ntawm cov qauv, gastritis, dyspeptic mob thiab lwm yam tsis kaj siab tshwm sim. Acidity hauvplab tuaj yeem qis, ib txwm thiab siab.
Txawm hais tias "muaj koob npe" ntawm pH siab, feem ntau cov neeg muaj acidity qis los yog ib txwm muaj. Cov tom kawg yog los ntawm 0.8 mus rau 1.5.
Npaj plab acid
Txo acidity tshwm sim nrog kev ntxhov siab tas li thiab kab mob inflammatory. Qhov no tshwm sim vim qhov excitation ntawm lub paj hlwb sympathetic, uas ncaj qha cuam tshuam rau kev tsim cov kua txiv gastric. Kev txo qis hauv acidity ua rau muaj kev puas tsuaj hauv kev zom zaub mov thiab mob plab. Cov zaub mov tseem nyob hauv kab noj hniav, pib rot, txhim kho kev tsim cov kab mob pathogenic. Tus neeg raug kev txom nyem los ntawm flatulence thiab xeev siab. Cov tom kawg yog cov lus teb rau lub plab spasm. Ntxiv mus, cov txheej txheem ntawm kev nqus ntawm tag nrho cov as-ham muaj nyob rau hauv peb cov zaub mov yog nquag cuam tshuam, uas ua rau muaj kev cuam tshuam ntawm tag nrho lub cev. Los ntawm txoj kev, nws yog nyob rau hauv lub hauv paus ntawm ib tug natural txo nyob rau hauv pH tom qab 40 xyoo uas ib tug neeg pib muaj hnub nyoog sai heev. Qhov ntawd yog, hydrochloric acid nyob rau hauv lub plab yeej cuam tshuam kev noj qab haus huv ntawm tag nrho cov kab mob.
Lub plab, xav tsis thoob los ntawm kev loj hlob ntawm cov kab mob, pib ua haujlwm tiv thaiv, ua rau mob. Nws raug kho nrog tshuaj uas ntxiv inhibit qhov tsim ntawm hydrochloric acid - thiab lub voj voog kaw. Ib tug neeg raug yuam mus ntsib kws kho mob tas li.
Txawm tias kub siab, uas peb tau xav tias yog qhov tshwm sim ntawm kev nce ntxiv hauv cov kua txiv hmab txiv ntoo, suav tias tsuas yog cov khoom ntawm acetic fermentation.
BNyob rau hauv lub plab mob, lactic acid pib ua kom nquag plias. Vim qhov tsis muaj peev xwm ntawm lub plab los tsim cov hnoos qeev txaus, nws ua rau cov phab ntsa ntawm lub cev puas. Nyob rau hauv tas li ntawd, qhov kev kuaj mob yog gastroduodenitis.
Parasites thiab qis plab acid
Cov kab mob tsis tuaj yeem nyob hauv lub plab noj qab haus huv (txawm li cas los xij, qhov no tsis suav nrog lawv qhov chaw nyob hauv lwm lub cev thiab lub cev ntawm lub cev), vim tias hydrochloric acid tau hlawv lawv. Tab sis sai li sai tau thaum nws txo qis, cov kab mob parasites pib vam meej, ua rau cov tsos mob tsis zoo. Kev nqus cov as-ham tseem cuam tshuam ntau dua, muaj kev pheej hmoo ntawm kev ua xua rau zaub mov (yog tias cov cab "tsis nyiam" cov zaub mov uas lawv noj).
Npaj plab acid
Txawm hais tias muaj kev xav ntawm ntau tus kws kho mob gastroenterologist, hyperacidity tsawg dua li cov acidity tsawg. Qhov txaus ntshai yog tias nrog ntev hypersecretion ntawm gastric kua txiv, ulcers ntawm txoj hlab pas thiab plab tshwm. Tus neeg mob muaj kev txhawj xeeb txog kev kub siab thiab mob. Qhov no yog qhov twg proton twj tso kua mis inhibitors, Omez thiab nws cov analogues, yuav pab tau. Cov tsos mob tau zoo nrog kev pab ntawm antacids - Gaviscon, Phosphalugel, thiab lwm yam.
txhawm rau kuaj xyuas cov acidity siab, yuav tsum tau kuaj ntsuas, vim tias raws li cov tsos mob nws yooj yim rau kev tsis meej pem nrog qis qis.
Kev txiav txim siab ntawm plab acidity
Hydrochloric acid hauv plab (uas yog, nws qib) yog txiav txim los ntawm ntau txoj hauv kev.
- Kev soj ntsuam. Nws yog ua tiav siv lub raj tshwj xeeb uas cov ntsiab lus ntawm lub plab nqus.
- Intragastric pH-metry. Sensors ntsuas acidity ncaj qha hauv plab.
Txoj kev thib ob yog suav tias yog cov ntaub ntawv tshaj plaws.
plab acidity yog ib yam uas kws kho mob feem ntau saib tsis taus, tab sis nws yog qhov tseem ceeb heev hauv kev kuaj mob thiab kho tus kab mob GI.
