Nyob hauv peb lub cev muaj ib lub cev uas muaj peev xwm rov qab los - nws yog lub siab. Raws li kev cuam tshuam ntawm ntau yam tsis zoo, cov qog no muaj kev ntxhov siab loj heev, thiab nws cov hlwb tuag los yog rov qab mus rau hauv cov ntaub so ntswg adipose. Nyob rau hauv kev kho mob ntawm daim siab, ib tug xov tooj ntawm cov tshuaj yog siv, ib tug ntawm cov uas yog Exhol. Cov lus qhia rau kev siv cov tshuaj no, indications, contraindications, nta ntawm kev kho mob thiab lwm yam ntaub ntawv muaj txiaj ntsig tau nthuav tawm hauv kab lus no.
Form and composition
Cov tshuaj no muaj nyob rau hauv daim ntawv ntawm cov tshuaj ntsiav, txhua tus muaj cov tshuaj nquag - ursodeoxycholic acid hauv qhov nyiaj ntawm 250 mg, nrog rau cov khoom siv pabcuam: silicon dioxide, magnesium stearate, calcium hydrogen phosphate dehydrate, povidone., lactose monohydrate thiab lwm yam.
tshuaj ua haujlwm li cas?
Cov yam ntxwv ntawm cov tshuaj siv tshuaj "Exhol" cov lus qhia rau kev siv piav qhia hauv qab no: nws yog cov tshuaj hepatoprotective nrog cov nyhuv choleretic.
Cov tshuaj nquag muaj cov nyhuv hauv qab no:
- txo cov synthesis ntawm cov roj cholesterol hauv lub siab, txo nws txoj kev nqus hauv cov hnyuv thiab cov ntsiab lus hauv cov kua tsib;
- nce qhov zoo ntawm cov roj cholesterol dissolution nyob rau hauv cov kua tsib excretion system, stimulating tsim ntawm no zais cia thiab txo nws lithogenicity;
- stimulates bile acid ntau ntau;
- ua kom zais zais ntawm plab hnyuv thiab pancreatic secretions;
- nce lipolytic enzyme kev ua haujlwm;
- muaj cov nyhuv hypoglycemic;
- stimulates ib nrab lossis ua tiav resorption ntawm cov cholesterol-hom pob zeb;
- txo qis saturation ntawm cov kua tsib nrog cov roj cholesterol, txav los ntawm pob zeb;
- muaj cov khoom ntawm immunomodulator, tswj cov lus teb hauv lub siab;
- txo cov kev qhia ntawm antigens concentrated ntawm daim nyias nyias ntawm hepatocytes;
- tswj tus naj npawb ntawm T-lymphocytes, interleukins-2;
- txo cov naj npawb ntawm elsinophils.
Pharmacokinetics ntawm cov tshuaj yog dab tsi?
Cov tshuaj "Exhol", cov lus qhia rau kev siv uas tau piav qhia hauv tsab xov xwm no, yog tus cwj pwm los ntawm kev nqus dej hauv cov hnyuv loj thiab muaj peev xwm hla cov placenta. Qhov ntsuas qhov siab tshaj plaws ntawm cov tshuaj hauv cov ntshav tau mus txog tom qab 1-3 teev thiab sib npaug li 5.5 mmol / l. Ursodeoxycholic acid yog protein ntau khi thiab metabolized nyob rau hauv daim siab hlwb mus rau hauv taurine thiab glycine conjugates, uas yog excreted rau hauv cov kua tsib. Cov khoom lag luam metabolic tau tawm nrog cov quav los ntawm 50-70%. Ib qho me me ntawm cov khoom tsis hloov pauv nkag mus rau hauv txoj hnyuv, qhov twgyog hloov los ntawm cov kab mob mus rau lithocholic acid, uas yog sulfated nyob rau hauv daim siab thiab tag nrho tawm ntawm lub cev los ntawm cov hnyuv.
Tshuaj qhia rau leej twg?
Cov lus qhia ncaj qha rau kev noj tshuaj "Exhol", cov lus qhia rau kev siv hu rau cov xwm txheej hauv qab no:
- thawj kab mob siab biliary cirrhosis uas tsis muaj cov cim qhia ntawm decompensation;
- qhov xav tau kom yaj cov pob zeb me me thiab nruab nrab cov roj cholesterol, raug rau kev ua haujlwm ntawm lub zais zis;
- gastritis (biliary reflux);
- mob siab mob siab;
- kab mob siab hauv cawv;
- primary sclerosing cholangitis;
- cystic fibrosis ntawm daim siab;
- tsis-alcoholic steatohepatitis;
- biliary dyskinesia.
Nrog cov kev qhia no, Exhol capsules thiab ntsiav tshuaj feem ntau tau muab los ntawm kws kho mob thiab ua kom pom kev ua haujlwm siab.
YContraindications
Cov tshuaj muaj ursodeoxycholic acid yog contraindicated nyob rau hauv cov kab mob hauv qab no:
- presence of hypersensitivity to drug Cheebtsam;
- tsis ua haujlwm li qub thiab lub zais zis empyema;
- muaj pob zeb uas muaj feem ntau ntawm calcium, kuaj pom los ntawm X-ray;
- fistula hauv plab hnyuv;
- kab mob siab ntev;
- kab mob plab hnyuv;
- cholecystitis lossis cholangitis nyob rau theem mob;
- decompensated cirrhosis ntawm daim siab;
- kab mob ntawm lub gallbladder, nws cov ducts thiab txoj hnyuv;
- xeeb tubthiab lactation;
- Cov menyuam yaus hnub nyoog qis dua 3;
- raum thiab siab tsis ua hauj lwm;
- obturation ntawm bile excretion pathways.
Nyob rau hauv lub xub ntiag ntawm cov contraindications, nws tsis pom zoo kom sau Exhol rau cov neeg mob. Cov lus qhia qhia tau hais tias qhov kev kho no tsis pom qhov tsis zoo rau tus menyuam hauv plab thaum kawm txog tsiaj, txawm li cas los xij, tsis muaj kev tshawb fawb txaus rau cov poj niam cev xeeb tub.
Cov lus qhia tshwj xeeb
Hauv txoj kev tshwj xeeb qhia qee qhov nuances ntawm kev siv "Exhol" txhais tau tias siv. Cov kws kho mob cov lus hais txog cov tshuaj no yog qhov zoo, tab sis lawv nyiam cov poj niam ntawm lub hnub nyoog yug me nyuam rau qhov tseeb tias kev tiv thaiv ntxiv yuav tsum tau saib xyuas thaum kho nrog cov khoom siv tshuaj no. Ntxiv nrog rau cov tshuaj tiv thaiv hormonal, qhov ua tau zoo ntawm kev txo qis, kev tiv thaiv kev tiv thaiv kev xeeb tub yuav tsum tau siv. Nws tsis pom zoo kom xav txog kev kho mob nrog Exhol rau cov poj niam cev xeeb tub. Cov lus qhia qhia tau hais tias nyob rau hauv qhov xwm txheej no qhov kev pheej hmoo rau leej niam yuav tsum siab dua qhov kev pheej hmoo rau tus menyuam hauv plab. lactation yuav tsum nres yog hais tias cov tshuaj no yog noj los ntawm tus poj niam pub niam mis.
Yog tias tus menyuam muaj hnub nyoog 3 xyoos, yog tias tsim nyog, cov tshuaj "Exhol" tuaj yeem muab rau nws. Cov lus qhia siv rau cov menyuam yaus hu kom ceev faj thaum kho cov menyuam yaus hnub nyoog qis dua 4 xyoos, vim lawv yuav muaj teeb meem nqos cov tshuaj ntsiav.
Yuav siv tshuaj li cas?
Cov lus qhia zoo tshaj plaws rau kev kho mob nrog Exhol -cov lus qhia rau kev siv. Daim duab ntawm lub cuab yeej no yuav pab koj tiv thaiv koj tus kheej los ntawm kev yuav khoom cuav.
Cov tshuaj noj hauv qhov ncauj, nyiam dua thaum yav tsaus ntuj. Nws tsis pom zoo kom zom cov tshuaj ntsiav, nws yog qhov zoo dua los haus dej me me. Yog tias tus neeg mob hnyav dua 34 kg, ces nws yog qhov zoo dua los xaiv qhov kev ncua nrog tib yam tshuaj.
Qhov koob tshuaj yog nyob ntawm lub hnub nyoog thiab lub hom phiaj ntawm kev kho.
Rau lub hom phiaj ntawm kev faib cov pob zeb hauv lub gallbladder thiab ducts, Exhol tau noj ib hnub ntawm 10 mg / kg rau 6-12 lub hlis thiab ob peb lub hlis tom qab ua tiav cov txiaj ntsig kev tiv thaiv.
Yog tus neeg mob kho mob reflux gastritis, ces nws tau muab tshuaj ib ntsiav tshuaj ib hnub ib zaug rau ib ncig ntawm ob lub lis piam mus rau rau lub hlis, thiab yog hais tias tsim nyog - mus txog 24 lub hlis.
Kev kho mob ntawm biliary cirrhosis yog ua raws li cov txheej txheem: ib hnub - 10-15 mg / kg nrog lub sijhawm ntawm kev txiav txim siab ntawm tus kws kho mob.
Rau lwm yam kab mob suav nrog hauv cov npe qhia rau kev lees paub, qhov ntau npaum ntawm cov tshuaj thiab lub sijhawm ntawm nws cov kev tswj hwm yog teem los ntawm tus kws kho mob ntawm tus kheej.
Tsis tas li, txoj hauv kev tshwj xeeb yuav tsum tau teem caij rau cov menyuam yaus thiab cov tub ntxhais hluas nrog cov tshuaj "Exhol". Cov lus qhia rau kev siv rau cov menyuam yaus hnub nyoog qis dua 3 xyoos qhia tias yuav tsum tau txhaj tshuaj ntawm 10-20 mg / kg ntawm lub cev hnyav ib hnub. Qhov tseeb rationing ntawm cov tshuaj thiab lub sij hawm ntawm kev kho mob yog teem los ntawm tus kws kho mob tus kheej.
Puas muaj kev phiv thiab noj ntau dhau nrog kev kho mob?
Thaum noj tshuaj "Exhol" yuavCov kev phiv xws li:
- mob nraub qaum;
- digestive ntshawv siab;
- nce kev ua haujlwm ntawm daim siab transaminases;
- ua xua;
- Calcium saturation ntawm gallstones;
- recurrence of psoriasis;
- allopecia.
Yog tias cov teebmeem no tshwm sim, koj yuav tsum tsis txhob noj Exhol. Cov lus qhia rau kev siv, cov muaj pes tsawg leeg ntawm uas yog luv luv nthuav tawm nyob rau hauv tsab xov xwm no, qhia tau hais tias tsis muaj ib tug neeg ntawm overdose ntawm cov tshuaj no.
Txawm li cas los xij, yog tias tus neeg mob muaj cov tsos mob ntawm kev qaug cawv, kev kho mob yuav tsum tau ua.
Kev sib xyaw nrog lwm cov tshuaj
Kev sib koom ua ke nrog aluminium-muaj anthacyanins thiab ion-pauv resins txo qhov nqus tau zoo ntawm Exhol. Cov tshuaj lipid-txo qis, neomcin, estrogens lossis progestins ua kom cov cholesterol saturation thiab txo cov pob zeb tawg.
Txoj kev tau txais nyiaj
Thawj daim ntawv uas koj yuav tsum tau nyeem ua ntej noj tshuaj "Exhol" - cov lus qhia rau kev siv. Daim ntawv tso tawm ntawm cov tshuaj no nyob rau hauv daim ntawv ntawm cov tshuaj ntsiav yog qhov zoo tshaj plaws nyob rau hauv kev sib raug zoo nrog tag nrho cov cholesterol pob zeb, uas nws loj tsis pub dhau 15-20 hli. Nyob rau tib lub sijhawm, lub gallbladder yuav tsum tau ntim nrog cov formations tsis ntau tshaj li ib nrab, thiab cov ducts tau khaws 100% ntawm lawv txoj haujlwm kom tshem tawm cov kua tsib.
Nyob rau hauv cov txheej txheem ntawm kev kho mob tsom rau kev tshem tawm cov roj cholesterol, nws yuav tsum tau uatswj kev ua haujlwm ntawm daim siab enzymes: transaminases, alkaline phosphatase, GGT thiab bilirubin. Cholecystography yuav tsum tau ua ib zaug txhua 4 lub lis piam txhua 3 lub hlis ntawm kev kho. Txhua rau lub hlis, tus neeg mob yuav tsum tau kuaj xyuas lub siab kom ntsuas qhov kev kho mob zoo.
Thaum lub pob zeb tawg tiav lawm, kev siv "Exhol" yuav tsum txuas ntxiv rau peb lub hlis ntxiv txhawm rau txhawm rau txhawm rau rhuav tshem cov pob zeb tsis pom thiab tiv thaiv kev tsim cov tshiab.
Yog hais tias txawm tias ib feem ntawm cov pob zeb tawg tsis pom nyob rau thawj rau lub hlis lossis ib xyoos ntawm kev kho mob, qhov no txhais tau hais tias nws tsis pom zoo kom kho txuas ntxiv vim nws tsis muaj txiaj ntsig.
Analogues thiab synonyms
Yog tus neeg mob rau ib qho laj thawj vim li cas tsis tuaj yeem muab "Exhol", ces nws tuaj yeem hloov los ntawm ib qho ntawm cov ntsiab lus:
- capsules "Ursodeoxycholic acid";
- YUrsoliv capsules;
- Ursosan capsules;
- Ursodex film-coated tablets;
- Ursorom Rompharm capsules;
- Urdox capsules;
- ncua kev siv sab hauv "Ursofalk";
- Ursofalk capsules;
- Ursolit capsules;
- Livodex film-coated ntsiav tshuaj;
- Grinterol capsules
Yog hais tias tus neeg mob muaj ib tus neeg intolerance rau ursodeoxycholic acid, los yog nws tau qhia nws ineffectiveness nyob rau hauv kev kho mob, ces cov tshuaj no yuav tsum tau hloov nrog ib tug analogue, uas yog lub Cholenzym ntsiav tshuaj daim ntawv. Cov tshuaj no yog cov tshuaj sib xyaw ua kelos ntawm cov kua tsib qhuav, powdery dihydrated pancreas thiab mucous cov ntaub so ntswg ntawm txoj hnyuv me ntawm nyuj. Raws li qhov kev txiav txim, "Holenzim" yog hais txog cov tshuaj choleretic.
Cov tshuaj no yog contraindicated nyob rau hauv hypersensitivity, mob thiab exacerbated mob pancreatitis. Raws li kev tawm tsam los ntawm kev noj cov tshuaj no, kev tsis haum tshuaj yuav tshwm sim nyob rau hauv daim ntawv ntawm lacrimation, yaug thiab daim tawv nqaij pob.
Tus nqi thiab tshuaj xyuas tus neeg mob
Cov tshuaj no yog tsim los ntawm lub tuam txhab kws tshuaj hauv tebchaws CJSC "Kanofarma ntau lawm", uas nyob hauv cheeb tsam Moscow. Tus nqi ntawm ib pob Exhola nyob rau nruab nrab hauv Russia yog 125 rubles. Ntau tus neeg mob nco txog qhov ua tau zoo ntawm cov tshuaj no, qhov yooj yim ntawm kev noj nws thiab tus nqi pheej yig. Cov neeg muaj kab mob ntawm daim siab thiab kab mob biliary nco ntsoov tias cov txiaj ntsig zoo tau ua tiav thaum kho nrog Exhol. Nrog rau kev ua tau zoo, cov neeg mob nco txog qhov ua tau zoo ntawm qhov kev kho no.
Nws tsim nyog sau cia tias cov lus piav qhia ntawm cov khoom siv tshuaj no tsis tiav. Yog xav paub ntxiv txog cov tshuaj "Exhol", koj yuav tsum nyeem kom meej cov lus qhia muab nrog cov tshuaj. Tsuas yog tus kws kho mob tuaj koom nrog rau kev teem caij ntawm qhov kev kho no. Kev noj tshuaj rau tus kheej tuaj yeem ua rau muaj kev phom sij rau koj txoj kev noj qab haus huv.
