"Chondroitin sulfate" yog qhov tseem ceeb ntawm cov khoom siv tshuaj lom neeg ntawm cov pob txha mos. Nrog rau cov kab mob pathological lossis raug mob, kev sib koom tes pib tawg. Lub zog ntuj tsis txaus los ua kom rov tsim dua tshiab, thiab yog li ntawd xav tau ib qho khoom siv dag zog los ntawm cov tshuaj tshwj xeeb, chondroprotectors.
Thaum tus neeg mob tau kawm nrog cov tshuaj no, lub hnab sib koom ua ke thiab pob txha pob txha pob txha tau maj mam rov qab los, cov kua dej tso rau hauv qhov sib koom ua ke nce, cov khoom sib txuas ntawm cov ntaub so ntswg yog nrawm, kev loj hlob ntawm arthrosis txo, Cov tsos mob xws li kev txwv tsis pub txav mus los, mob, sib koom ua ke raug tshem tawm.
Txoj kev teeb meem thiab nws cov ntsiab lus
"Chondroitin sulfate" muaj ntau hom kev tso tawm:
- lyophilizate rau kev tsim cov tshuaj rau kev txhaj tshuaj intramuscular: ib qho ntxeem tau dawb loj, compressed hauv daim ntawv ntawm cov ntsiav tshuaj (hmoov hauv ib lub ntim ntawm 100 mg hauv ampoules tsis muaj xim, tsib ampoules hauv ib lub xovtooj ntawm tes.hlwv, ib los yog ob lub hlwv hlwv hauv ib lub thawv; nyob rau hauv ib lub thawv ntawm tsib los yog kaum ampoules);
- kev daws rau kev txhaj tshuaj intramuscular: cov kua ntshiab lossis daj daj nrog cov paj tsw qab ntxiag uas yog cov yam ntxwv ntawm benzyl cawv (ib lossis ob milliliters ntawm cov tshuaj hauv cov iav tsis muaj xim, tsib ampoules hauv pob blister strip, ib lub thawv muaj ib los yog ob pob ntawm Chondroitin Sulfate txhaj tshuaj).
Ib lub vial ntawm lyophilisate muaj 100 mg ntawm cov khoom xyaw nquag. Ib milliliter ntawm cov tshuaj muaj 100 mg ntawm chondroitin sodium sulfate, uas yog, active ingredient, raws li zoo raws li excipients: dej rau txhaj, roj av cawv.
Pharmacodynamic Specification
"Chondroitin sulfate" ua cov khoom tseem ceeb ntawm proteoglycans, uas ua ke nrog collagen fibers tsim cov pob txha mos matrix nrog cov khoom nram qab no:
- Nws muaj txiaj ntsig ntawm hom chondroprotective.
- Inhibits cov haujlwm ntawm cov enzymes uas ua rau degradation ntawm pob txha pob txha.
- Txhim kho cov txheej txheem metabolic hauv cov pob txha subchondral thiab pob txha mos.
- Txhawb kev tsim cov proteoglycans los ntawm chondrocytes.
- cuam tshuam rau kev sib pauv ntawm calcium thiab phosphorus hauv cov pob txha mos, txhawb nws txoj kev tsim dua tshiab thiab koom nrog hauv kev tsim cov khoom tseem ceeb ntawm pob txha mos thiab pob txha. Cov tshuaj no yog anti-inflammatory thiab analgesicCov nyhuv, txo cov kev tso tawm ntawm cov kab mob sib kis mus rau hauv cov kua synovial, txo qhov mob tshwm sim los ntawm synoviocytes thiab macrophages ntawm lub synovial membrane, inhibiting secretion ntawm prostaglandin E2 thiab leukotriene B4..
- Kev siv "Chondroitin sulfate" ua rau nws muaj peev xwm tiv thaiv kev tawg ntawm cov ntaub so ntswg, ua kom rov qab kho cov pob txha pob txha pob txha, normalizes cov kua dej hauv cov pob qij txha, yog li txhim kho lawv txoj kev mus los thiab tso cai kom txo tau qhov mob hnyav. thiab txo qhov mob, nrog rau txo qhov xav tau ntawm cov tshuaj tiv thaiv uas tsis yog-steroidal npaj. Yog tias kev hloov pauv degenerative tshwm sim hauv cov pob txha mos, ces cov tshuaj ua raws li kev hloov kho. Tus neeg mob hnov cov nyhuv ntawm cov tshuaj no ob mus rau peb lub lis piam tom qab nws siv, qhov kev siv ntawm kev sib koom ua ke txo qis, cov tsos mob ntawm reactive synovitis raug tshem tawm, thiab muaj kev nce hauv ntau qhov kev tawm suab hauv cov pob qij txha. Thaum txoj kev kho tas lawm, cov txiaj ntsig ntawm nws kav li ntawm peb lub hlis mus rau rau lub hlis.
Qhov no lees paub cov lus qhia siv rau "Chondroitin sulfate".
YPharmacokinetics
Cov tshuaj no tau zoo nqus tau thaum txhaj tshuaj intramuscular, tom qab ib teev qhov siab tshaj plaws tau mus txog, txo qis dua li plaub caug yim teev. Cov tshuaj accumulates tsuas yog nyob rau hauv cov ntaub so ntswg cartilaginous articular, nkag mus rau hauv lub synovial membrane. "Chondroitin sulfate" muaj nyob rau hauv lub synovialUa kua kaum tsib feeb tom qab txhaj tshuaj, tom qab uas nws nkag mus rau hauv pob txha mos ntawm cov leeg, qhov siab tshaj plaws concentration yog mus txog tom qab ob hnub.
Thaum twg siv tshuaj?
Lyophilisate yog siv rau osteoarthritis ntawm tus txha nqaj qaum thiab peripheral pob qij txha. Nyob rau hauv daim ntawv ntawm kev daws, nws yog siv rau degenerative-dystrophic pathologies ntawm tus txha nqaj qaum thiab pob qij txha: intervertebral osteoarthritis thiab osteochondrosis; osteoarthritis ntawm pob qij txha nyob rau hauv periphery. Cov tshuaj no yog siv los ua kom cov callus thaum lub sij hawm tawg.
YContraindications
Raws li cov lus qhia rau "Chondroitin sulfate", cov contraindications yog:
- thrombophlebitis, los ntshav nyiam thiab los ntshav ncaj qha;
- tus neeg mob lub sijhawm cev xeeb tub thiab lactation;
- rhiab heev rau ib lossis lwm qhov ntawm cov khoom siv tshuaj.
Ib qho ntxiv contraindication rau kev siv cov tshuaj nyob rau hauv daim ntawv ntawm kev daws yog tus me nyuam lub hnub nyoog ntawm tus neeg mob.
Yuav siv cov khoom li cas thiab qhov xav tau npaum li cas
Chondroitin sulfate yog muab tshuaj intramuscularly. Txhawm rau npaj cov tshuaj raws li lyophilisate, nws yog ib qho tsim nyog yuav tsum yaj tus neeg sawv cev uas muaj nyob rau hauv ampoule hauv ib milliliter dej rau kev txhaj tshuaj ua ntej txhaj tshuaj. Xav tau ntau npaum li cas: txhua hnub, ib milliliter. Tom qab txhaj tshuaj thib plaub, yog tias ua tau zoo, koj tuaj yeem nce qhov ntau npaum li ob milliliters.
Lub sijhawm kho - los ntawm 25 mus rau 30 txhaj tshuaj. Rau lub hlis tom qab koj tuaj yeem ua tauua cov kev kawm tshiab. Lawv lub sijhawm yuav tsum tau txiav txim los ntawm tus kws kho mob. Txhawm rau kom ua tiav cov txiaj ntsig ruaj khov, tsawg kawg 25 cov tshuaj txhaj tshuaj yuav tsum tau ua, qhov no, kev khaws cia ntev ntev ntawm cov txiaj ntsig zoo yog pom. Rov ua cov chav kawm yog siv los tiv thaiv cov exacerbations tshiab. Txhawm rau tsim cov callus, cov tshuaj yuav tsum tau siv txhua hnub rau 3-4 lub lis piam.
Kev mob tshwm sim thiab ua tau ntau dhau
Raws li cov lus qhia rau kev siv qhia, Chondroitin sulfate muaj kev phiv:
- hemorrhages ntawm qhov chaw txhaj tshuaj;
- ua xua tshwm sim.
Yog tias cov tsos mob tsis zoo tshwm sim, nws raug nquahu kom txiav cov tshuaj.
Tam sim no tsis muaj ntawv tshaj tawm txog kev noj tshuaj ntau dhau hauv cov neeg mob.
cov lus qhia tshwj xeeb, analogues
Raws li cov lus qhia, cov tshuaj tsis muaj kev cuam tshuam rau kev mloog zoo, nrog rau cov yam ntxwv nrawm ntawm cov tshuaj tiv thaiv psychomotor, thiab yog li ntawd tus neeg muaj peev xwm tsav tsheb thiab lwm yam txheej txheem nyuaj thaum kho tsis tau. pauv.
Tsis muaj ntaub ntawv qhia txog kev ua tau zoo thiab kev nyab xeeb ntawm cov tshuaj thaum cev xeeb tub thiab pub niam mis. Nws yog qhov zoo dua kom tsis txhob kho nrog cov tshuaj no thaum lub sijhawm ntawd. Yog tias muaj qhov xav tau ceev, nws yuav tsum cuam tshuam kev pub niam mis thaum lub sijhawm kho.
Tseem tsis tau muaj ntaub ntawv qhia txog kev siv tshuaj rau cov neeg mob hluas. Qhov no kuj tau lees paub los ntawm kev tshuaj xyuas thiab cov lus qhia rau "Chondroitin sulfate".
Raws li cov analogues yog: "Artra", "Artradol", "Artogistan", "Artravir", "Artrafik", "Mukosat", "Drastop", "Chondroitin", "Chondrolon", "Chondroitin-AKOS", "Chondroguard", "Chondroxide".
Artra
Ib tug stimulator ntawm regeneration nyob rau hauv cov ntaub so ntswg cartilaginous.
Glucosamine thiab sodium chondroitin sulfate koom nrog hauv biosynthesis ntawm cov ntaub so ntswg sib txuas, tiv thaiv pob txha mos, txhawb kev tsim dua tshiab. Cov tshuaj muaj cov tshuaj tiv thaiv kab mob nruab nrab.
Chondrolone
Cov tshuaj tiv thaiv pob txha mos. Lub synthesis ntawm proteoglycans yog stimulated, enzymatic kev ua si uas ua rau kev puas tsuaj ntawm pob txha mos yog inhibited, cov metabolism hauv pob txha mos yog txhim kho, vim li ntawd, lub hauv paus ntawm cov pob txha thiab pob txha mos yog tsim.
Cov tshuaj txo qhov mob thiab mob. Qhov saum npoo ntawm pob txha mos tau rov qab los, kev tso tawm ntawm cov kua dej synovial raug tswj, qhov mob yuav tsis tshua pom, thiab qhov ntau ntawm kev txav ntawm cov pob qij txha nce.
Tshuaj xyuas txog "Chondroitin sulfate"
Kev tshuaj xyuas feem ntau yog qhov zoo. Cov kev zam yog cov xwm txheej uas cov neeg mob raug yuam kom thim tawm ntawm cov tshuaj vim muaj kev cuam tshuam tsis zoo.
