Tshuaj "Rozuvastatin" cov lus qhia rau kev siv cov yam ntxwv ua cov tshuaj txo qis lipid los ntawm pawg statins. Qhov kev txiav txim ntawm tus neeg sawv cev xaiv no yog raws li kev sib tw inhibition ntawm HMG-CoA reductase. Raws li qhov tshwm sim ntawm kev siv tshuaj "Rozuvastatin" (cov lus qhia rau kev siv paub meej tias qhov no), catabolism ntawm LDL nce ntau zaus, qhov ntsuas ntawm lub siab LDL receptors nce, thiab VLDL txo qis. Raws li cov tshuaj pharmacokinetic ntawm no lipid-txo cov tshuaj, cov txiaj ntsig kho tau zoo los ntawm kev noj nws tau pom xya hnub tom qab pib txoj kev kho, ncav cuag nws qhov txiaj ntsig siab tshaj plaws tom qab plaub lub lis piam.
Cov chaw tsim khoom pom zoo kom noj cov ntsiav tshuaj Rosuvastatin rau cov neeg uas muaj kev sib xyaw ntawm hypercholesterolemia (hom IIb) lossishypercholesterolemia IIa (xws li heterozygous) ua ib qho ntxiv rau kev noj haus.
Tib lub sijhawm, cov tshuaj lipid-txo qis no yog qhov ua tau zoo tshaj plaws thaum lwm txoj kev kho mob (lub cev ua haujlwm, poob phaus) tsis ua rau kev ua tiav ntawm kev kho kom raug. Tsis tas li ntawd, cov lus qhia rau kev siv qhia txog kev siv cov tshuaj rosuvastatin uas yog cov tshuaj pabcuam thaum kho homozygous familial hypercholesterolemia.
Nws yog txwv tsis pub sau cov tshuaj no yog tias tus neeg mob muaj kab mob siab, myopathy, lossis mob hnyav hauv lub raum. Thaum cev xeeb tub, koj yuav tsum tsis txhob noj cov tshuaj lipid-txo tus neeg sawv cev Rosuvastatin. Cov tshuaj no kuj yog contraindicated thaum lub sij hawm lactation. Tsis tas li ntawd, nws tsis pom zoo kom noj cov ntsiav tshuaj ib txhij nrog cyclosporine lossis thaum muaj qhov tsis haum rau lawv cov khoom. Cov neeg uas tsis muaj hnub nyoog kaum yim yuav tsum tsis txhob raug sau npe rau tus neeg sawv cev xaiv Rosuvastatin. Cov lus qhia rau kev siv tsis qhia tias noj nws thaum haus cawv, tsim lub raum tsis ua haujlwm lossis kab mob siab.
Cov tshuaj txo lipid no yuav tsum tau siv nrog kev ceev faj zoo rau cov neeg uas muaj electrolyte, endocrine lossis metabolic ntshawv siab, hypothyroidism lossis arterial hypotension. Nrog sepsis,Kev tswj tsis tau mob vwm, proteinuria, kev raug mob hnyav thiab kev phais mob, nws tseem tsim nyog tsis kam noj Rosuvastatin. Tsis tas li ntawd, cov kab mob ntawm cov leeg thiab cov hnub nyoog tshaj rau caum-tsib yog cov txheeb ze contraindications.
Hauv kev xaus, nws yuav tsum tau hais txog qhov tshwm sim tsis zoo, qhov tshwm sim tuaj yeem tshwm sim los ntawm kev noj Rosuvastatin. Piv txwv li, ntau tus neeg mob yws ntawm qhov mob plab, cem quav, kiv taub hau thiab xeev siab. Tsis tas li ntawd, muaj kev pheej hmoo me me ntawm kev tsim myopathy, proteinuria, asthenic syndrome thiab myalgia.
