Amylase - nws yog dab tsi thiab nws ua haujlwm li cas hauv lub cev? Lub sij hawm no yog to taub raws li tag nrho cov pab pawg neeg ntawm enzymes, uas yog koom nyob rau hauv lub npe dav dav - "amylase". Muaj peb hom tshuaj no: alpha, beta thiab gamma. Rau tib neeg lub cev, alpha-amylase yog qhov tseem ceeb tshwj xeeb. Peb yuav tham txog nws tam sim no.
Nws yog synthesized nyob qhov twg?
Amylase - yog dab tsi? Lub npe ntawm cov enzyme no los ntawm Greek lo lus "amylon", uas txhais tau tias "starch" hauv Lavxias. Hauv tib neeg lub cev, amylase muaj nyob rau hauv ntau cov ntaub so ntswg thiab kabmob. Nws yog ib qho enzyme (hydrolase) uas zom cov carbohydrates nyuaj. Qhov concentration ntawm cov enzyme no yog siab heev nyob rau hauv lub txiav. Nws yog synthesized los ntawm acinar hlwb ntawm lub cev thiab yog secreted los ntawm lub pancreatic ducts mus rau hauv lub digestive ib ntsuj av, ntau precisely rau hauv duodenum. Ntxiv nrog rau pancreas, cov qog ua kua qaub kuj muaj peev xwm ua kom cov amylase. Ib qho enzyme uas muaj nyob rau hauv qaub ncaug pib lub hydrolysis ntawm starch thaum zaub mov tseemyog nyob rau hauv lub qhov ncauj kab noj hniav. Yog li, cov txheej txheem ntawm kev zom zaub mov pib sai li sai tau thaum cov zaub mov nkag mus rau hauv lub qhov ncauj.
Amylase qib ntsuas
Amylase - yog dab tsi? Yuav ua li cas txiav txim siab nws qib hauv tib neeg lub cev? Qhov tseeb yog tias pancreas, qhov twg cov enzyme no tsim tawm, tau muab cov ntshav zoo heev. Feem ntau, ib feem ntawm cov enzyme (nws qhov tsawg kawg nkaus) nkag mus rau hauv cov hlab ntsha. Tsis tas li ntawd, qhov hydrolase no, dhau los ntawm ob lub raum, raug tso tawm nrog rau cov zis.
ntshav alpha amylase - yog dab tsi? Peb mam li tham txog qhov no kom ntxaws ntxiv hauv qab no.
Thaum twg qhov kev xeem teem sijhawm?
Pab ntsuas qhov mob ntawm lub cev kuaj ntshav. Amylase - nws yog dab tsi, nyob rau hauv dab tsi kab mob nws nce nyob rau hauv cov ntshav? Qib ntawm alpha-amylase hauv cov ntshav ntshav tuaj yeem nce ntau zaus nrog cov kab mob hauv qab no:
- mob hnyav lossis mob pancreatitis thaum lub sijhawm exacerbation.
- Pancreonecrosis focal.
- Oncology ntawm pancreas.
- Cholelithiasis (nyob rau hauv lub xub ntiag ntawm ib tug neeg pob zeb nyob rau hauv lub ductal system).
- Acute appendicitis.
- raum tsis ua haujlwm.
- plab los ntshav.
- plab hnyuv.
- AIDS.
- Viral kab mob siab.
- Mumps.
- Sarcoidosis.
- Typhoid.
- Nyob rau hauv plab kab noj hniav (saum toj).
Alpha-amylase qib qis lossis tsis pom nyob rau hauv txhua kistag nrho necrosis ntawm tus txiav, nrog oncology ntawm lub cev ntawm theem 4, vim hais tias cov qog nqaij hlav yog hloov los ntawm qog, nrog rau cystic fibrosis (congenital pathology). Thaum lub sij hawm kev phais, thaum ib feem tseem ceeb ntawm lub caj pas raug tshem tawm, qib ntawm amylase kuj tuaj yeem txo qis.
Nyob rau hauv cov xwm txheej twg amylase nce hauv cov ntshav?
Ntshav amylase - nws yog dab tsi thiab qhov ntsuas no hloov pauv li cas hauv cov kab mob pancreatic? Hauv kev mob pancreatitis, nws nce nrawm dua li ntawm 4-6 teev tom qab pib qhov kev tawm tsam thiab tseem nyob rau theem siab txog li tsib hnub. Kev nce hauv kev ua haujlwm enzymatic ntawm amylase hauv cov ntshav plasma feem ntau tsis nyob ntawm qhov hnyav ntawm tus kab mob. Ntau zaus qhov opposite. Nrog rau kev puas tsuaj ntawm cov txiav, qhov tseem ceeb ntawm kev nce ntxiv ntawm pancreatic alpha-amylase tsis pom. Thiab qhov nce hauv nws qib yuav qhia tau tias muaj kev tso tawm ntau ntxiv ntawm amylase rau hauv kev ncig.
Thaum twg nws tuaj yeem ua kom nws cov concentration hauv cov ntshav? Qhov no feem ntau tuaj yeem pom nyob rau hauv cov xwm txheej hauv qab no:
- Hypersecretion ntawm pancreatic kua txiv.
- Kev ua txhaum tag nrho ntawm kev tawm ntawm pancreatic secretions los ntawm pancreatic ducts rau hauv duodenum.
- Kab mob pancreas nws tus kheej lossis cov kab mob nyob ze nws. Qhov kub ntawm cov kab mob hauv nruab nrog cev nce thiab cov ntshav ntws hauv lawv nce, yog li muaj kev tso tawm ntau ntxiv ntawm cov enzyme rau hauv cov ntshav.
- Kev mob rau tus txiav.
- Kev noj haus tsis tu ncua thiab haus cawv.
YUrine diastasis
Thaum glomerular pom tshwm sim, amylase raug tso tawm, ib nrab ntawm nws yog reabsorbed los ntawm tubules. Qhov seem ib nrab yog tawm hauv cov zis. Kev nce hauv cov zis diastase tau pom nyob rau hauv tib yam mob raws li kev nce hauv nws cov concentration hauv cov ntshav. Nws yuav tsum raug sau tseg tias kev ua haujlwm ntawm amylase hauv cov zis yog kwv yees li 10 npaug siab dua li nws cov haujlwm hauv cov ntshav.
Amylase - nws yog dab tsi thiab dab tsi yog cov qauv kev lees paub rau qhov ntsuas no hauv cov ntshav thiab zis? Qhov no yuav tham ntxiv.
Alpha-amylase - yog dab tsi? Qhov tseem ceeb ntawm cov ntshav thiab zis
Thaum nyeem cov txiaj ntsig ntawm kev tshuaj ntsuam rau amylase, koj yuav tsum tau ua tib zoo saib xyuas cov units uas nws tau qhia. Nws yog kev cai siv "u / l" - units ntawm amylase ib liter ntawm cov ntshav thiab "mkkatal / l" - microkatal hauv ib liter. Nws yuav tsum tau qhia meej ntawm no tias "katal" yog ib chav ntsuas rau kev ntsuas kev ua haujlwm ntawm lub catalyst.
Tsis tas li ntawd, nyob rau hauv ntau lub chaw soj nstuam, cov txheej txheem thiab cov tshuaj reagents rau kev txiav txim siab amylase yuav txawv me ntsis, yog li koj yuav tsum tau xyuam xim rau cov qauv ntawm qhov ntsuas no, uas ib txwm qhia ib sab ntawm qhov kev tshawb fawb. Thawj tus lej yog tus nqi qis kawg nkaus, qhov thib ob yog qhov siab tshaj plaws.
Cov qauv ntawm cov ntshav alpha-amylase thiab zis diastase muaj nyob hauv cov lus hauv qab no:
| Npe ntawm kev tshuaj ntsuam | Norm in mkkatal/l | Norm in U/L |
| blood alpha amylase | 15-30 | 17-100 |
| YUrine diastasis | 25-100 | mus txog 1000 |
Nyob rau hauv rooj plaub uas muaj qhov ua tau zoo me ntsis (los ntawm ob peb units) thiab ib tus neeg zoo, qhov no tsis yog pathology. Koj yuav tsum txhawj xeeb thaum nce qhov txiaj ntsig ntawm amylase ob peb zaug. Kev tawm tsam ntawm tus mob pancreatitis tuaj yeem ua rau cov zis diastase thiab ntshav amylase ntau dua 100 zaug. Feem ntau cov kev tawm tsam no nrog xeev siab, ntuav thiab mob hnyav. Tus mob no yuav tsum tau mus pw hauv tsev kho mob tam sim.
Yuav ua li cas kuaj ntshav thiab zis amylase?
ntshav rau qhov kev tshuaj ntsuam no yog muab los ntawm cov hlab ntsha. Feem ntau nws yog noj thaum sawv ntxov ntawm lub plab khoob, tab sis yog tias koj yuav tsum txiav txim siab theem ntawm amylase sai sai, piv txwv li, thaum muaj kev mob hnyav ntawm tus mob pancreatitis, qhov no tuaj yeem ua tau txhua lub sijhawm. Xws li kev tshuaj ntsuam tuaj yeem ua los ntawm ib qho chaw kuaj biochemical. Raws li txoj cai, cov txheej txheem enzymatic rau kev kuaj mob amylase kev ua haujlwm yog siv hauv cov chaw sim niaj hnub no. Qhov no yog ib txoj hauv kev tshwj xeeb thiab meej. Kev tshuaj xyuas sai txaus.
Nws tseem zoo dua los kuaj zis rau diastasis thaum sawv ntxov. Ib feem nruab nrab ntawm cov zis yog coj mus rau qhov chaw kuaj mob tam sim ntawd. Kev tshawb fawb ntawm qhov ntsuas no yog qhov tseem ceeb hauv kev kuaj mob ntau yam.
