Ntau yam tshuaj tau tshwm sim vim yog cov tshuaj sib xyaw ua ke hauv tib neeg lub cev. Chenodeoxycholic acid, uas zoo tua cov pob zeb, yog ib yam khoom zoo li no. Kev npaj uas muaj cov kua qaub no tau siv ntev los kho thiab tiv thaiv kab mob cuam tshuam rau lub gallbladder.
Kev piav qhia thiab cov khoom ntawm cov khoom
Chenodeoxycholic acid muaj peev xwm ua kom cov pob zeb tawg. Qhov no yog ib qho ntawm cov kua tsib tseem ceeb tshaj plaws rau lub cev, tsim nyob rau hauv daim siab hlwb. Ib zaug nyob rau hauv lub gallbladder, nws ua tshwj xeeb ntawm cov pob zeb cholesterol, dissolving lawv, tiv thaiv daim siab thiab tag nrho lub cev los ntawm kab mob gallstone. Ntxiv nrog rau cov pob zeb yaj, cov kua qaub no txo cov roj cholesterol synthesized hauv daim siab. Nws tshwm sim los ntawm cov kua tsibNws ua rau nws tsis txaus, yog li tsim cov pob zeb roj cholesterol tshiab tsawg.
Tshuaj
Kev npaj nrog chenodeoxycholic acid nyob rau hauv muaj pes tsawg leeg:
- Chenofalk. Tshuaj los ntawm kws kho mob Falk Pharma GmbH, ua nyob rau hauv lub teb chaws Yelemees.
- Henochol. Lub tuam txhab tshuaj ICN GALENIKA. Lub teb chaws ntawm keeb kwm - Serbia.
- Henosan. Tshuaj ua los ntawm PRO. MED. CS Praha a.s. hauv Czech koom pheej.
Npaj cov khoom tsim nyog tuaj txawv teb chaws yog cov khoom siv tshuaj zoo thiab siv tau zoo.
Daim ntawv thov
Tshuaj yog tshuaj rau tus mob cholelithiasis nrog cov pob zeb roj cholesterol txog li 20 millimeters inch. Hauv qhov no, lub gallbladder yuav tsum ua nws txoj haujlwm, uas yog, sib sau, mloog zoo thiab tso tawm cov kua tsib thaum nkag mus rau hauv cov zaub mov hauv lub plab. Cov pob zeb roj (cholesterol) yog cov zais zis ntau tshaj plaws, vim tias cov roj cholesterol ua lub hauv paus ntawm tag nrho cov pob zeb tsim hauv lub cev. Kev siv cov tshuaj saum toj no yog lwm txoj hauv kev zoo rau kev phais mob ntawm tus kab mob gallstone.
Cov lus qhia rau chenodeoxycholic acid
Txoj kev siv tshuaj:
- "Henofalk" yog siv txhua hnub, ib hnub ua ntej yuav mus pw. Qhov koob tshuaj yog 15 mg rau ib kg ntawm lub cev hnyav. Capsules tsis tau zom thiab ntxuav nrog dej raws li qhov xav tau. Qhov siab tshaj plaws koob tshuaj yog 1.5 grams tauj ib hnub. Kev kho mob ntev - los ntawm peb lub hlis mus rau 3 xyoos. Kev kho mob yuav tsum nyob rau hauv kev tswj hwm ultrasound, txij li qhov tsis muaj qhov txo qis hauv txoj kab uas hla ntawm lub pob zeb tom qab rau lub hlis yog lub hauv paus rau kev tso tseg cov tshuaj.
- "Khenochol" yog siv nyob rau hauv ib hnub koob tshuaj ntawm 15-18 mg ib kilogram ntawm tus neeg mob qhov hnyav. Cov chaw tsim khoom pom zoo kom faib cov tshuaj rau hauv peb koob tshuaj thiab noj ib ntsiav tshuaj thaum sawv ntxov thiab yav tav su, thiab 2 ntsiav tshuaj thaum yav tsaus ntuj. Qhov siab tshaj plaws uas tuaj yeem noj ib hnub yog 1.5 grams. Lub sijhawm kho yog nyob ntawm qhov loj ntawm lub pob zeb, tab sis kev kho yuav tsum tsis pub tsawg dua 6 lub hlis, thiab nyob rau hauv rooj plaub uas cov pob zeb ncav cuag 15-20 hli, koj yuav tsum noj cov tshuaj mus txog ob xyoos. Tom qab ntsuas lub cheeb ntawm lub pob zeb nrog kev pab los ntawm ib tug ultrasound diagnostic apparatus, tom qab 6 lub hlis, qhov expediency ntawm ntxiv noj Henohol yog soj ntsuam. Nyob rau hauv cov ntaub ntawv ntawm kev ua tiav ntawm cov pob zeb roj cholesterol hauv cov neeg mob ua rau muaj pob zeb ntau ntxiv vim cov yam ntxwv ntawm cov metabolism, nws raug nquahu kom noj cov tshuaj rau lwm lub hlis, ib ntsiav tshuaj ib hnub, rov ua cov chav kawm txhua hli txhua 90 hnub.
- "Henosan" yog siv rau kev tswj qhov ncauj, suav cov koob tshuaj txhua hnub ntawm 15 mg ib kilogram ntawm lub cev hnyav. Qhov nruab nrab, 3-6 capsules tau txais (tsis pub ntau tshaj 1.5 grams tauj ib hnub), uas tau noj ib zaug thaum yav tsaus ntuj. Capsules yuav tsum tau nqos tag nrho nrog cov dej txaus. Kev kho mob yuav tsum tau txuas ntxiv rau 6 lub hlis mus rau ib xyoos. Qhov kev ua tau zoo ntawm cov pob zeb tawg yog ntsuas tom qab rau lub hlis siv ultrasound. Rau cov hom phiaj tiv thaiv, rov ua cov chav kawm raug pom zoohauv ob peb lub hlis.
Nws yuav tsum tau kho nrog tshuaj nruj me ntsis raws li cov lus qhia rau kev siv chenodeoxycholic acid.
YContraindications
Contraindications rau noj tshuaj chenodeoxycholic acid yog:
- Pob zeb loj dua 20 mm.
- Pob zeb nrog lub zog calcium uas muaj zog.
- Ib lub gallbladder puv pob zeb thiab tsis ua tiav nws txoj haujlwm.
- mob cholecystitis.
- mob siab lossis mob siab ntev ntawm txhua yam.
- mob o ntawm cov kua tsib.
- Decompensation thiab end-stage cirrhosis.
- Kev mob lub siab tsis ua haujlwm.
- raum tsis ua haujlwm.
- duct blockage by pob zeb.
- Peptic ulcer ntawm lub plab, duodenum thaum exacerbation.
- Malabsorption syndrome.
- Y Ulcerative colitis, enteritis.
- Kev cev xeeb tub.
- Npaj Ntsuag.
- Intolerance rau cov khoom tseem ceeb lossis cov khoom pabcuam.
Chenodeoxycholic acid tso tawm daim ntawv
Lawv tsim tshuaj raws li hauv qab no:
- "Henofalk" yog tsim nyob rau hauv capsules nrog ib koob ntawm 250 mg ntawm cov khoom xyaw nquag. Cov ntaub ntawv ntawm 25, ntim rau hauv ib lub thawv ntawm ob lossis plaub lub hlwv.
- "Chenochol" yog tsim nyob rau hauv capsules, cov ntsiab lus ntawm chenodeoxycholic acid nyob rau hauv uas yog 250mg. Cov tshuaj ntsiav raug kaw hauv hlwv ntawm yim. Lub thawv muaj xya lub hlwv.
- "Henosan" muaj nyob rau hauv cov tshuaj ntsiav uas muaj chenodeoxycholic acid 250 mg, hlwv ntawm kaum capsules hauv ib lub thawv ntawm tsib.
Side effects
Chenodesoxycholic acid kev npaj yog feem ntau zam tau zoo. Ntawm cov kev mob tshwm sim, kev tsis haum tshuaj me me tuaj yeem ua tau, tshwm sim hauv daim ntawv ntawm pob khaus ntawm daim tawv nqaij lossis khaus khaus. Hauv cov neeg mob noj cov tshuaj ntau npaum li cas rau lub sijhawm ntev, nws muaj peev xwm ua tau ntau tshaj li cov qauv ntawm cov kab mob siab transaminases hauv kev kuaj ntshav biochemical, uas qhia tau hais tias muaj kev cuam tshuam rau cov tshuaj lom ntawm daim siab hlwb, qhov twg metabolic kev hloov pauv ntawm cov tshuaj nquag tshwm sim..
Qhov tseem ceeb nce hauv ALAT thiab ASAT yuav tsum tau hloov kho ntau npaum li cas. Paroxysmal mob nyob rau hauv txoj cai hypochondrium (biliary colic) yuav tshwm sim thaum lub pob zeb yaj los ntawm cov tshuaj. Yog tias qhov mob yog luv luv, ces cov tshuaj txuas ntxiv yam tsis muaj kev hloov pauv. Cov tsos mob ntawm plab hnyuv hauv daim ntawv ntawm raws plab tshwm nyob rau hauv cov koob tshuaj ntau thiab intensive dissolution ntawm pob zeb, uas yog nrog los ntawm ib tug nce nyob rau hauv cov ntsiab lus ntawm cov rog nyob rau hauv cov quav.
