Dab tsi yog tshuaj "Mydocalm"? Qhov kev kho no pab tau li cas? Peb yuav nthuav qhia cov lus qhia thiab cov yam ntxwv ntawm cov tshuaj hauv nqe lus nug hauv qab no. Koj tseem yuav kawm paub kho cov tshuaj no li cas, nws raug nqi npaum li cas thiab nws muaj pes tsawg leeg.
daim ntawv kho mob, ntim, piav qhia, muaj pes tsawg leeg
Mydocalm tuaj rau cov khw muag tshuaj li cas (cov tshuaj no pab tau dab tsi, peb yuav qhia hauv qab no)? Cov cuab yeej no muaj nyob rau hauv cov ntsiav tshuaj, nrog rau hauv cov tshuaj npaj rau kev tswj xyuas parenteral.
Round thiab dawb Mydocalm ntsiav tshuaj, tus nqi ntawm cov lus qhia hauv qab no, suav nrog tolperisone hydrochloride. Raws li cov khoom xyaw ntxiv, cov ntsiab lus ntawm cov tshuaj muaj xws li: anhydrous colloidal silicone, citric acid monohydrate, pob kws starch, stearin, hydroxypropyl methylcellulose 2910, talc, macrogol 6000, microcrystalline cellulose, dye, lactose monohydrate thiab titanium dioxide.
Cov cuab yeej no yog tsim los ntawm cov hlwv, uas tau muab tso rau hauv cov thawv ntawv.
Cov tshuaj pob tshab "Mydocalm" hauv ampoules kuj muaj tolperisone hydrochloride thiab lidocaine. Tsuas yogTsis tas li ntawd, cov tshuaj no muaj cov khoom xyaw hauv qab no: talc, citric acid monohydrate, lactose monohydrate, anhydrous colloidal silicone, macrogol 6000, microcrystalline cellulose, stearin, titanium dioxide, pob kws starch, dub hlau oxide, hydroxypropyl methylcellulose 2910, liab hlau oxide thiab daj. hlau oxide.
Cov tshuaj "Mydocalm" hauv ampoules muaj nyob rau hauv cov thawv yas, uas tau muab tso rau hauv cov thawv ntawv.
Basic nta
Mydocalm yog dab tsi? Dab tsi pab tau cov tshuaj no? Raws li cov lus qhia, cov tshuaj nyob rau hauv nqe lus nug belongs rau cov leeg nqaij relaxants ntawm cov aminoketone pawg, uas muaj ib tug central nyhuv.
Cov txiaj ntsig ntawm cov tshuaj no muaj feem xyuam nrog kev tswj hwm ntawm ib feem ntawm (caudal) reticular tsim. Kev siv cov tshuaj no ua rau muaj kev cuam tshuam ntawm kev nce reflex excitability ntawm tus txha caj qaum. Nws kuj cuam tshuam cov hlab ntsha xaus (peripheral).
Txoj kev tshuaj
Cov tshuaj "Mydocalm" (qhov sib xyaw ntawm cov tshuaj no nrog rau lwm tus yog txais tau, tab sis nyob rau hauv cov xwm txheej tshwj xeeb) yog N-anticholinergic. Nws cov tshuaj nquag muaj qhov ua kom ruaj khov ntawm daim nyias nyias hauv cov fibers thawj (afferent), nrog rau lub cev muaj zog neurons. Cov nyhuv ntawm cov tshuaj no yog vim nws lub peev xwm los cuam tshuam rau kev ua haujlwm reflex ntawm tus txha caj qaum synapses.
Nws tseem yuav tsum tau muab sau tseg tias cov tshuaj no ua rau qeeb qeeb ntawm kev tawm ntawm cov neeg nyob nruab nrab. Qhov no tshwm sim vim inhibition ntawm cov txheej txheem ntawm calcium nkag mus rau hauvsynaptic lug pom nyob rau hauv paj hlwb.
Kev cuam tshuam ntawm tus neeg sawv cev no ntawm txoj hauv kev reticulospinal tshwj xeeb tshaj tawm thaum cov txheej txheem excitation qeeb. Ib yam li ntawd, cov nyhuv tshuaj loog hauv zos tau tshwm sim (vim cov ntsiab lus ntawm lidocaine hauv nws).
Drug kinetics
Tus neeg sawv cev hauv nqe lus nug yog nqus tau zoo los ntawm txoj hnyuv. Nws cov concentration (qhov siab tshaj plaws) hauv cov ntshav yog mus txog 65 feeb tom qab noj. Metabolism ntawm cov tshuaj tshwm sim nyob rau hauv lub raum thiab lub siab. Tolperisone derivatives raug tso tawm hauv cov zis.
Kev rov ua dua ntawm "Mydocalm" tsis cuam tshuam rau kev ua haujlwm ntawm lub raum thiab lub siab, nrog rau cov txheej txheem ntawm hematopoiesis.
Cov tshuaj no txo cov kev sim ua kom tawv nqaij thiab hypertonicity ntawm cov leeg nqaij. Cov khoom siv tshuaj ntawm cov tshuaj no nquag siv los txo cov leeg nqaij rigidity thiab pathological hypertonicity, uas cuam tshuam nrog cov kab mob extrapyramidal.
Nws tseem yuav tsum tau muab sau tseg tias cov tshuaj no txhawb kev ua haujlwm ntawm tib neeg (nws txav). Tsis tas li ntawd, nws tsis cuam tshuam rau cerebral cortex nyob rau hauv ib txoj kev, tag nrho tswj cov theem ntawm wakefulness ntawm tus neeg mob.
Raws li cov lus qhia, kev kho mob nrog "Mydocalm" ua rau muaj kev cuam tshuam me ntsis antispasmodic thiab adrenoblocking. Qhov no txhim kho cov ntaub so ntswg perfusion.
Nyob rau hauv cov txheej txheem ntawm kev tshawb fawb soj ntsuam mus ntev, cov tshuaj no tsis muaj kev cuam tshuam rau hematopoiesis thiab lub raum ua haujlwm.
Cov tshuaj "Mydocalm": los ntawm dab tsipab?
Cov cuab yeej no tau qhia rau siv hauv cov xwm txheej hauv qab no:
- Nyob rau hauv kev xyaum menyuam yaus rau kev kho mob ntawm Little's disease (uas yog, spastic paralysis). Tsis tas li ntawd, cov tshuaj no yog siv rau encephalopathy ntawm lwm lub hauv paus chiv keeb nrog cov tsos mob ntawm cov leeg nqaij dystonia.
- Nyob rau hauv cov xwm txheej uas tau nrog los ntawm pathological hypertonicity ntawm cov nqaij ntshiv striated, tsim los ntawm pathologies ntawm (neurological) organic keeb kwm (piv txwv li, nrog ntau yam sclerosis, encephalomyelitis, myelopathy, residual cuam tshuam ntawm mob cerebral ncig, kab mob. ntawm pyramidal tract).
- Nyob rau hauv cov xwm txheej uas tshwm sim los ntawm kev puas tsuaj rau cov hlab ntsha innervation (piv txwv li, nrog acrocyanosis, intermittent angioedema).
- Nrog cov leeg nqaij hypertonicity, cov leeg nqaij contracture uas nrog cov kab mob ntawm lub cev ntawm kev txav mus los (piv txwv li, spondylosis, arthrosis ntawm lub luj tshib, lub hauv caug thiab lub duav pob qij txha, spondylarthrosis, lumbar thiab cervical syndromes).
- Thaum muaj mob tom qab thrombotic ntawm cov ntshav ntws thiab lymphodynamics.
- Raws li kev kho mob tom qab kev kho mob hauv orthopedic thiab kev raug mob.
- Nrog trophic ulcers uas tsim nyob rau hauv qis extremities, angiopathy (xws li diabetogenic), angiosclerosis obliterans thiab thromboangiitis, nrog rau cov kab mob autoimmune (nrog Raynaud's kab mob thiab kab mob scleroderma).
txwv tsis pub siv
Thaum twg nws ua tsis tausau tshuaj thiab txhaj tshuaj "Mydocalm"? Kev siv cov tshuaj no yog contraindicated nyob rau hauv:
- myasthenia gravis;
- hypersensitivity rau tolperisone thiab paub ua xua rau lidocaine;
- mus txog peb lub hlis ntawm hnub nyoog (hauv ntsiav tshuaj daim ntawv mus txog ib xyoos).
Yuav siv li cas
Txoj kev siv cov tshuaj no yog tsim los ntawm tus kws kho mob nyob ntawm seb tus kab mob, nrog rau kev ua siab ntev ntawm cov tshuaj.
Rau cov neeg laus, cov tshuaj tau muab rau hauv tus nqi ntawm 150-450 mg (ib hnub ib zaug) hauv peb koob tshuaj. Qhov pib noj ntawm cov tshuaj no yog 50 mg peb zaug ib hnub twg. Nrog kev ua haujlwm tsis txaus, nws nce ntxiv.
Rau kev txhaj tshuaj intramuscular, cov tshuaj yog siv hauv qhov ntau ntawm 200 mg ib hnub twg (hauv ob txoj kev txhaj tshuaj), thiab tso tshuaj - 100 mg (ib zaug ib hnub). Hauv qhov thib ob, yuav tsum tau txhaj tshuaj qeeb heev.
Rau cov menyuam yaus hnub nyoog qis dua peb lub hlis (txog 6 xyoos), cov koob tshuaj ntawm cov lus nug raug suav nrog raws li cov qauv hauv qab no: 5-10 mg ib kg ntawm qhov hnyav (peb zaug hauv ib hnub). Rau tus menyuam hnub nyoog 7-14 xyoos, nws raug nquahu kom siv cov ntsiav tshuaj hauv ib hnub ntawm 2-4 mg ib kg ntawm lub cev (peb zaug hauv ib hnub).
qhov ncauj noj ntawm "Mydocalm" yuav tsum tau ua ke nrog kev noj zaub mov.
Side actions
Kev noj tshuaj nrog tus neeg mob siab tuaj yeem ua rau cov leeg tsis muaj zog, cov tsos mob dyspeptic (xeev siab, tsis xis nyob thiab ntuav), nrog rau mob taub hau.
Nrog cov tshuaj txhaj tshuaj sai sai, txo qis hauvAD.
Nrog ib tus neeg intolerance rau cov tshuaj, kev ua xua tshwm sim. Raws li txoj cai, thaum cov tshuaj txo qis, cov kev mob tshwm sim ploj sai heev.
Drug interaction
Tsis muaj kev sib cuam tshuam paub los txwv kev siv tshuaj hauv nqe lus nug. Txawm li cas los xij, nws yuav tsum tau muab sau tseg tias tolperisone muaj kev cuam tshuam rau hauv nruab nrab lub paj hlwb. Tib lub sijhawm, cov tshuaj tsis ua rau qaug zog, yog li nws tuaj yeem ua ke nrog hypnotics thiab sedatives, nrog rau cov tshuaj uas muaj ethanol.
Thaum noj ib txhij, "Mydocalm" txhim kho cov nyhuv ntawm niflumic acid. Yog tias tsim nyog los ua ke cov neeg sawv cev zoo li no, nws yuav tsim nyog los txo cov koob tshuaj tom kawg.
Peripheral leeg relaxants, tshuaj rau cov tshuaj loog dav dav thiab cov tshuaj psychotropic, nrog rau "Clonidine" ua kom cov txiaj ntsig ntawm tolperisone.
Nqi thiab tshuaj xyuas
Mydocalm nqi npaum li cas? Tus nqi ntawm cov cuab yeej no yog hais txog 185 rubles.
Cov tshuaj xyuas cov neeg mob hais tias cov tshuaj hauv nqe lus nug zoo heev, tshwj xeeb tshaj yog cov kab mob ntawm cov pob qij txha. Tsis tas li ntawd, qhov kev kho mob no pab tau zoo nrog cov ntshav tsis zoo hauv lub hlwb, suav nrog cov uas tau tshwm sim tom qab raug mob lub hlwb.
Ntawm cov kev tshuaj xyuas tsis zoo yog cov uas hais tias cov tshuaj "Mydocalm" tsis yog panacea. Feem ntau, cov tshuaj no yog siv los ua kev kho mob.
