Ciprofloxacin yog lub ntsiab lus tseem ceeb ntawm cov tshuaj kho mob "Ciprobai", uas yog tus cwj pwm los ntawm qib siab ntawm cov kab mob tua kab mob.
Tus neeg saib xyuas tshuaj muaj zog tiv thaiv ntau yam kab mob gram-negative thiab gram-positive pathogens. Cov cuab yeej bactericidal ntawm cov khoom nquag yog vim cov txheej txheem ntawm kev tua cov kab mob topoisomerases ntawm hom II (topoisomerase IV thiab topoisomerase II), tsis muaj cov txheej txheem ntawm replication, transcription, kho thiab recombination ntawm cov kab mob DNA yog tsis yooj yim sua.
Cov lus qhia rau kev siv
Raws li cov lus qhia rau kev siv Ciprobay thiab lwm yam tshuaj ciprofloxacin, lawv raug sau rau kev kho mob ntawm cov kab mob tsis yooj yim thiab tsis yooj yim uas yog provoked los ntawm cov kab mob uas nkag siab rau cov txiaj ntsig ntawm ciprofloxacin thiab cuam tshuam rau cov zis, qhov muag, ob lub raum, pob qij txha, qhov chaw mos, cov pob txha, plab kab noj hniav (hauvnrog rau peritonitis, kab mob kab mob ntawm lub biliary ib ntsuj av los yog digestive ib ntsuj av), cov ntaub so ntswg mos, daim tawv nqaij. Tsis tas li, cov tshuaj siv los kho cov kab mob ua pa - lawv raug pom zoo rau mob ntsws los ntawm Haemophilus spp., Enterobacter spp., Staphylococcus spp., Legionella spp., Branhamella spp., Klebsiella spp., Escherichia coli, Proteus spp., Pseudomonas spp. Sinusitis, otitis media, gonorrhea, sepsis, kab mob hauv cov neeg uas tsis muaj zog tiv thaiv kab mob, xaiv decontamination ntawm txoj hnyuv, anthrax nyob rau hauv cov ntaub ntawv pulmonary yog kho nrog Tsiprobay thiab nws cov analogues.
Contraindications rau kev sau ntawv
Raws li qhia los ntawm cov lus qhia rau kev siv "Tsiprobay", kiag li contraindications yog:
- siv ua ke ib txhij nrog tizanidine (txuas nrog kev nce hauv plasma concentration ntawm cov ntshav tom kawg hauv cov ntshav thiab qhov tshwm sim ntawm cov tshuaj tiv thaiv tseem ceeb, piv txwv li, tsaug zog, hypotension);
- hnub nyoog qis dua 18 xyoo, tshwj tsis yog kho qee yam teeb meem ntawm CF hauv lub ntsws thiab tiv thaiv kab mob anthrax;
- cev xeeb tub, lactation txheej txheem;
- tus neeg tsis kam lees;
- Hypersensitivity rau fluoroquinolones.
txheeb ze contraindications tuaj yeem txiav txim siab:
- pathologies ntawm lub hauv nruab nrab lub paj hlwb (kev qaug dab peg, txo qib ntawm convulsive npaj los yog hnyav anamnesis);
- txwv cov ntshav ntws hauv cov hlab ntsha hauv hlwb, mob stroke lossis lub hlwb puas tsuaj;
- mob siab thiab raumua tsis tiav;
- kev puas siab puas ntsws: psychosis, kev nyuaj siab;
- laus laus.
Txoj cai rau noj thiab noj cov lus qhia
Tsiprobay thiab analogues ntawm cov tshuaj raws li ciprofloxacin tau noj hauv qhov ncauj, ntawm lub plab khoob, nrog dej, tsis hais zaub mov. Nws yog qhov tsis tsim nyog los haus cov ntsiav tshuaj nrog mis nyuj lossis kua dej uas muaj calcium. Yog tias nws tsis tuaj yeem noj cov tshuaj no sab hauv, nws raug sau rau hauv daim ntawv ntawm infusion daws. Tom qab normalization ntawm tus neeg mob tus mob, lawv raug xa mus rau kev noj tshuaj.
Cov tshuaj infusion yog muab tso rau hauv cov hlab ntsha loj, lub sijhawm ntawm cov tshuaj yog tsawg kawg 1 teev. Cov tshuaj tuaj yeem muab coj los ua ke nrog lwm cov kev daws teeb meem. Cov tshuaj noj hauv qab no tau pom zoo rau cov neeg laus:
- kab mob ntawm cov kab mob ua pa - 500 mg ntawm Ciprobay 2 zaug hauv ib hnub;
- cov kab mob urinary nyuaj - 250 lossis 500 mg 2 zaug;
- mob zais zis - ib zaug 250 mg;
- extragenital gonorrhea - 130 mg 2 zaug;
- tsis muaj kab mob gonorrhea - ib koob tshuaj 250mg;
- mob plab - 2 zaug hauv ib hnub, 500 mg;
- lwm cov kab mob sib kis - 500 mg 2 zaug;
- anthrax - 2 zaug ib hnub, 500 mg;
- kis kab mob uas ua rau muaj kev phom sij rau lub neej (septicemia, peritonitis, streptococcal pneumonia, kab mob ntawm pob qij txha thiab pob txha) - 2 zaug hauv ib hnub, 750 mg.
Tus nqi tshuaj
Tus nqi ntawm Ciprobay yuav txawv nyob ntawmCov khw muag tshuaj muag nws thiab qhov ntau npaum li cas ntawm cov tshuaj thiab thaj tsam ntawm 240 txog 420 rubles ib pob. Tus nqi sib txawv raws cheeb tsam.
Tsiprobay analogues
Cov qauv analogues ntawm cov tshuaj yog:
- "Aphenoxin";
- YBetaciprol;
- "Basijen";
- "Vero-Ciprofloxacin";
- "Ificipro";
- "Zindolin";
- Quintor;
- Liprokhin;
- Quipro;
- YMicroflox;
- Oftocypro;
- "Nirtsip";
- YCyflox;
- YCyloxane;
- "Tseprova";
- Ciprinol;
- Cyprobid;
- Ciprodox;
- Ciprobrin;
- Ciprolaker;
- YCiproxil;
- "Tsiprolet";
- YCiprolon.
Cia saib qee yam tshuaj kom ntxaws.
Zindolin
A broad-spectrum antimicrobial tshuaj, fluoroquinolone derivative. Cov tshuaj muaj peev xwm txo tau cov kab mob DNA gyrase (topoisomerases II thiab IV, uas yog lub luag haujlwm rau supercoiling ntawm chromosome DNA nyob ib ncig ntawm RNA nucleus, uas tsim nyog rau kev nyeem cov ntaub ntawv), cuam tshuam DNA ntau lawm, kev faib thiab kev loj hlob ntawm cov kab mob. Tsis tas li ntawd, cov tshuaj ua rau muaj kev hloov pauv morphological tseem ceeb (xws li daim nyias nyias thiab cov phab ntsa ntawm tes) thiab kev tuag sai ntawm cov kab mob ntawm tes.
Nws muaj cov kab mob bactericidal ntawm cov kab mob gram-tsis zoo thaum so thiab faib (vim tias nws muaj cov lus hais tsis yog ntawm DNA gyrase xwb, tab sis kuj txhawb nqa phab ntsa lysis.hlwb), rau hauv gram-zoo microbes - tsuas yog thaum faib.
Tsawg toxicity yog vim tsis muaj DNA gyrase hauv cov hlwb ntawm lub cev. Thaum kho nrog ciprofloxacin, tsis muaj qhov sib xyaw ua ke rau lwm cov tshuaj tua kab mob uas tsis koom nrog hauv qeb ntawm gyrase inhibitors, uas ua rau nws zoo tshaj plaws tiv thaiv cov kab mob uas tiv taus aminoglycosides, cephalosporins, penicillins, tetracyclines thiab lwm yam tshuaj.
Dab tsi lwm yam Tsiprobay analogues paub?
Ificipro
Cov tshuaj no yog ib qho piv txwv zoo ntawm cov tshuaj, thiab yog raws li tib lub ntsiab lus - nws yog ciprofloxacin.
Cov tshuaj no muaj txiaj ntsig zoo rau yuav luag txhua hom kab mob aerobic, indole-negative thiab indole-positive microorganisms: Proteus spp., Enterobacter spp., Morganella morganii, Hafnia spp., Providencia stuartii, Salmonella spp., Citrobacter spp., Vibrio cholerae, Yersinia enterocolitica, Vibrio parahaemolyticus, Moraxella catarrhalis, Neisseria meningitidis, Neisseria gonorrhoeae, Providencia spp., Haemophilus influenzae, Pseudomonas aeruginosa. etc.
Tshuaj yog muab rau yuav luag txhua yam kab mob sib kis, suav nrog cov ntaub ntawv hnyav. Lawv cov npe suav nrog cov kab mob ntawm cov kab mob ua pa, teeb meem gynecological, kab mob ntawm cov zis, musculoskeletal thiab cov cuab yeej sib koom, cov kab mob purulent, peritonitis,sepsis.
Analogues ntawm "Tsiprobaya" yuav tsum raug xaiv los ntawm kws kho mob.
Lyproquin
Cov tshuaj ua haujlwm ntawm cov tshuaj no yog tshuaj tua kab mob, lub ntsiab tseem ceeb yog ciprofloxacin. Txhawb nqa DNA gyrase, cuam tshuam kev lom neeg synthesis ntawm DNA, kev faib thiab kev loj hlob ntawm cov kab mob. Ua rau microbes thaum dormancy thiab loj hlob. Nws absorbed sai sai los ntawm lub plab hnyuv ib ntsuj av nyob rau hauv cov hnyuv thiab duodenum. Nkag mus rau hauv cov ntaub so ntswg, cov hlwb thiab cov kua dej, tsim kom muaj siab nyob rau hauv ob lub raum, lub siab cov qauv, lub gallbladder ducts, ntsws, sinus thiab bronchial mucosa, qhov chaw mos, zis, phagocytic hlwb, bile, hnoos qeev, pom nyob rau hauv lub prostate, cerebrospinal qaub qaub, kua dej., cov ntaub so ntswg rog, tawv nqaij, pob txha, cov leeg nqaij fibers, dhau los ntawm cov placenta. Muab tso rau hauv daim siab, tawm los ntawm lub raum nrog zis.
Reviews
Muaj ntau qhov kev tshuaj xyuas zoo txog cov tshuaj "Ciprobai" thiab nws cov analogues raws li cov tshuaj ciprofloxacin, vim nws cov txiaj ntsig zoo thaum kho cov kab mob sib kis thiab teeb meem.
Cov neeg mob tau tshaj tawm tias lawv tau siv cov tshuaj no rau qhov mob hnyav ntawm cov kab mob ua pa, cov zis, cov plab hnyuv siab raum, kev tsim tawm, cov pob qij txha.
Cov tshuaj, raws li cov neeg mob, tau zam ib txwm, tsis ua rau muaj kev cuam tshuam loj ntawm tus mob, nrog rau cov tsos mob ntawm dyspepsia. Tus mob ntawm cov neeg mob tsis normalizes tam sim ntawd, kwv yees li ntawm tsib los yog xya hnub ntawm kev kho mob rau cov kab mob loj, thiab nyob rau hauv lub thib peb los yog plaub - rau tej yam kev mob ntawm nruab nrab.nyuaj.
Cov me nyuam tsis tau sau cov tshuaj no, txawm li cas los xij, muaj cov ntaub ntawv hauv kev tshuaj xyuas tias cov tshuaj tau siv rau cov kab mob ua rau lub neej nyob rau hauv cov menyuam yaus tom qab 10 xyoo. Hauv qhov no, cov koob tshuaj tau suav los ntawm cov kws tshaj lij raws li lub cev hnyav ntawm tus menyuam thiab cov yam ntxwv ntawm tus kabmob.
Cov kws tshaj lij tsis pom zoo siv cov tshuaj hauv nqe lus nug ntawm koj tus kheej, nws yog qhov zoo tshaj kom tau txais tus kws kho mob pom zoo.
