Nws tsis muaj qhov zais cia tias ntshav qab zib yog qhov ua phem rau lub neej niaj hnub no. Tus kab mob no cuam tshuam rau txiv neej thiab poj niam, hluas thiab laus, cov hluas thiab cov menyuam yaus. Feem ntau, cov kws kho mob tau sau cov ntsiav tshuaj Galvus, cov lus qhia rau kev siv uas yuav tau tham hauv kab lus no.
tshuaj no yog dab tsi? Hauv qhov xwm txheej twg yog nws lub sijhawm teem sijhawm? Yuav tsum coj li cas? Puas muaj tej contraindications rau nws siv? Tag nrho cov no tuaj yeem kawm tau los ntawm kev ua tib zoo kawm cov lus pom zoo ntawm cov kws tshaj lij thiab cov neeg mob, nrog rau lawv cov kev tshuaj xyuas txog Galvus. Cov lus qhia rau kev siv, analogues ntawm cov cuab yeej thiab lwm yam ntaub ntawv hais txog nws muaj nyob rau hauv tsab xov xwm no.
Thawj ntawm tag nrho, kev sau ntawv
Yog, qhov no yog ib qho tseem ceeb tshaj plaws uas tib neeg tau saib xyuas thaum yuav tshuaj. Raws li cov lus qhia rau cov tshuaj "Galvus", nws active ingredient yog vildagliptin. Txhua ntsiav tshuaj ntawm cov tshuaj muaj tsib caug milligrams ntawm cov tshuaj no.
Lwm cov khoom xyaw yog microcrystalline cellulose (ze li 96 milligrams), lactose anhydrous (li 48 milligrams), sodium carboxymethyl starch (plaub milligrams), thiab magnesium stearate (2.5 milligrams).
Raws li tsim los ntawm cov chaw tsim khoom
Raws li tau hais los saum no, cov tshuaj tau nthuav tawm hauv cov ntsiav tshuaj. Qhov ntau npaum ntawm cov tshuaj yog ib txwm zoo ib yam - tsib caug milligrams ntawm cov tshuaj nquag. Qhov no tau teev nyob rau hauv cov lus qhia siv rau Galvus. Kev tshuaj xyuas ntawm ntau tus neeg mob npau taws rau qhov tseeb tias nws yooj yim heev. Tsis tas yuav saib ze ntawm lub pob nrog cov tshuaj, vim kev ntshai ntawm kev yuav khoom noj tsawg dua lossis ntau dua li qhov tsim nyog. Nws txaus los yuav tshuaj thiab coj raws li tus kws kho mob pom zoo.
Hauv qhov xwm txheej twg tuaj yeem pom zoo "Galvus 50"? Cov lus qhia rau kev siv cov tshuaj no muab cov lus teb tag rau lo lus nug no.
Spectrum of use of tshuaj
Raws li cov lus qhia, Galvus ntsiav tshuaj tau muab rau cov neeg mob uas muaj ntshav qab zib hom 2. Cov tshuaj no pab txhawb kev ua haujlwm ntawm lub txiav. Ua tsaug rau vildagliptin, lub peev xwm ua haujlwm ntawm tag nrho cov kab mob txhim kho.
Raws li cov kws tshaj lij thiab cov neeg mob lawv tus kheej, "Galvus" yog qhov siv tau tsuas yog siv rau kev kho mob ntshav qab zib hom 2, tshwj xeeb tshaj yog tias kev kho mob nrog kev noj zaub mov tshwj xeeb thiab pom zoo kev kawm lub cev.
Nyob rau hauv qhov no, cov nyhuv ntawm cov tshuaj yuav ntev thiab pheej.
Qee zaum, qhov tshwm sim ntawm kev noj cov tshuaj yuav tsis tshwm sim. Yuav ua li cas thiaj ua tau li ntawd? Nyob rau hauv cov xwm txheej zoo li no, raws li cov lus qhia rau kev siv thiabKev tshuaj xyuas ntawm cov neeg mob ntshav qab zib, "Galvus" tau muab tshuaj ua ke nrog lwm cov tshuaj raws li insulin lossis lwm yam tshuaj uas txhawb kev ua haujlwm ntawm txiav txiav.
Ua ntej peb yuav mus txuas ntxiv kev sib tham ntawm cov lus piav qhia ntawm kev kho mob, cia peb saib luv luv ntawm tus kab mob, uas yog qhov qhia tseem ceeb rau kev siv cov ntsiav tshuaj.
mob ntshav qab zib hom II. Qhov no yog dab tsi?
Qhov no yog hom mob ntshav qab zib mellitus ntau tshaj plaws, uas tshwm sim los ntawm kev tiv thaiv ntawm lub cev hlwb thiab cov ntaub so ntswg rau cov tshuaj insulin uas tsim los ntawm cov txiav. Qhov no txhais li cas hauv kev xyaum?
Insulin yog tsim los ntawm lub cev hauv qhov ntau txaus, tab sis cov hlwb ntawm lub cev rau qee yam laj thawj tsis nkag mus rau hauv kev sib raug zoo nrog nws. Feem ntau, kev rog rog, ntshav siab, kev ua neej nyob tsis muaj zog, kev ua neej tsis zoo, kev ua neej tsis txaus ntseeg (kev tsim txom cov khoom qab zib, pastries, dej qab zib thiab cov khoom zoo sib xws tiv thaiv keeb kwm ntawm kev noj zaub mov tsawg, txiv hmab txiv ntoo thiab zaub.
Tus kab mob endocrine loj no tshwm sim li cas? Nws yog ib qho tseem ceeb heev kom paub qhov no txhawm rau txheeb xyuas tus kab mob hauv lub sijhawm thiab pib kho raws sijhawm nrog Galvus lossis lwm yam tshuaj uas kws kho mob endocrinologist tau sau tseg.
Ua ntej tshaj, hom 2 mob ntshav qab zib tshwm sim nws tus kheej hauv qhov nqhis dej tas li thiab qhov ncauj qhuav, tso zis ntau zaus, cov leeg tsis muaj zog, khaus tawv nqaij, kho tsis zoo ntawm khawb thiab qhov txhab.
Tshuaj ntsuam tus kab mob nrog kev pab los ntawm kev kuaj ntshav rau cov piam thaj, qabzib, thiab lwm yam.
YogHauv cov xwm txheej tshwj xeeb, cov tshuaj hauv qhov ncauj puas tuaj yeem pom zoo los ntawm cov kws tshaj lij?
Thaum twg tshuaj tau tshuaj
Raws li cov lus qhia, cov tshuaj "Galvus" yog cov kws kho mob tau sau tseg rau kev kho mob ntawm hom 2 mob ntshav qab zib mellitus ntawm cov theem hauv qab no ntawm kev kho:
- pib. Ntawd yog, tsuas yog cov tshuaj siv ua ke nrog kev noj zaub mov kom zoo thiab kev ua si lub cev tsis zoo.
- Monotherapy. Kev noj vildagliptin thaum metformin yog contraindicated, txawm tias kev noj haus thiab kev tawm dag zog tsis muaj txiaj ntsig zoo rau tus neeg mob lub cev
- Ob tug (los yog ua ke) kho. "Galvus" tau muab tshuaj ua ke nrog lwm cov tshuaj tshwj xeeb (ntau dua, ib qho ntawm lawv): metformin, insulin, sulfonylurea derivatives thiab lwm yam.
- Triple Therapy. Thaum muab vildagliptin ua ke nrog metformin thiab insulin lossis metformin thiab sulfonylurea.
Cov tshuaj ua haujlwm li cas thaum nws nkag mus rau tib neeg lub cev? Cia peb kawm.
Pharmacokinetic nta ntawm cov tshuaj
Vildagliptin, ib zaug noj, yog nqus tau sai. Nrog rau bioavailability ntawm 85%, nws nkag mus rau hauv cov ntshav hauv ob teev tom qab noj. Qhov no yog pov thawj los ntawm cov lus qhia rau "Galvus". Kev tshuaj xyuas ntawm cov kws kho mob endocrinologist thiab lwm tus kws tshaj lij qhia tau hais tias qhov tshwj xeeb ntawm cov khoom xyaw nquag ntawm cov tshuaj no ua rau nws muaj txiaj ntsig sai rau tib neeg lub cev thiab nws txoj kev rov qab sai.
Vildagliptin nkag mus rau kev sib raug zooNrog cov ntshav plasma proteins thiab erythrocytes, tom qab ntawd nws tawm los ntawm ob lub raum (kwv yees li 85%) thiab cov hnyuv (15%).
Puas muaj contraindications rau cov tshuaj? Tau kawg, thiab qhov no yuav tau tham ntxiv.
Thaum tsis sau tshuaj
Raws li cov kws kho mob pom zoo thiab cov lus pom zoo ntawm cov neeg mob, "Galvus" yuav tsum tsis txhob noj yog tias ib tus neeg raug kuaj mob ntshav qab zib hom 1, yog tias muaj keeb kwm mob plawv tsis ua haujlwm ntawm qib plaub, xws li zoo li nyob rau hauv cov kab mob xws li lactic acidosis, metabolic acidosis, intolerance lactose, myocardial infarction, pathological tej yam kev mob ntawm lub ua pa system, ua xua, mob siab kab mob. Tsis tas li contraindications kiag li yog cev xeeb tub, lactation thiab lub hnub nyoog ntawm cov neeg mob mus txog kaum yim xyoo.
Ntxiv mus, thaum txiav txim siab seb yuav noj vildagliptin lossis tsis, ib tus yuav tsum tsis txhob hnov qab txog tus neeg intolerance rau cov khoom ntawm cov ntsiav tshuaj, uas yog, kev tsis haum tshuaj rau cov tshuaj nquag ntawm nws tus kheej thiab rau cov khoom siv ntawm cov tshuaj..
Ua tib zoo, uas yog, nyob rau hauv kev saib xyuas zoo thiab kev tswj hwm ntawm tus kws tshaj lij, muab tshuaj rau cov neeg mob uas mob pancreatitis, plawv tsis ua haujlwm lossis ntau yam kab mob ntev ntawm daim siab thiab ob lub raum.
Yuav ua li cas thiaj yuav tau noj tshuaj kom paub tias nws muaj txiaj ntsig?
lus pom zoo rau kev siv cov khoom
Cov tshuaj noj nrog lossis tsis muaj zaub mov. Ntxuav cov tshuaj nrog dej me me.
Kev kho tshuaj,Cov piam thaj hauv cov ntshav yuav tsum tau saib xyuas tsis tu ncua nrog glycemic kuaj strips.
Cov tshuaj noj ntau tshaj plaws txhua hnub yog ib puas milligrams ntawm vildagliptin.
Yuav ua li cas thiab ntau npaum li cas
Ua ntej tshaj plaws, nws yuav tsum tau hais tias lub sijhawm ntawm kev tswj hwm thiab kev siv tshuaj yog muab los ntawm tus kws kho mob, suav nrog lub tsev kho mob ntawm tus kab mob, cov kab mob sib kis thiab tus neeg mob txoj kev noj qab haus huv. Thiab tseem, cov lus qhia rau kev siv rau Galvus muaj cov lus qhia dav dav txog kev noj tshuaj li cas hauv qee qhov xwm txheej.
Thaum ua thawj zaug lossis monotherapy, cov tshuaj "Galvus", raws li cov chaw tsim khoom cov lus qhia, raug pom zoo kom noj tsib caug milligrams ib hnub (los yog ib ntsiav tshuaj). Yog tias peb tab tom tham txog kev sib xyaw ntawm vildagliptin nrog metformin, cov tshuaj tau noj ib ntsiav tshuaj ob zaug ib hnub.
Thaum siv vildagliptin nrog sulfonylurea tshuaj, Galvus raug tshuaj tsib caug milligrams ib hnub ib zaug, thaum sawv ntxov.
Rau peb txoj kev kho mob, nws raug nquahu kom noj ob ntsiav tshuaj ob zaug hauv ib hnub (tag kis thiab hmo ntuj).
Yog tias tus neeg mob tsis nco qab tshuaj, nws yuav tsum tau noj sai li sai tau, ncua sijhawm me ntsis ntawm cov tshuaj tom ntej. Qhov no yog qhov tsim nyog txhawm rau txhawm rau kom tsis txhob dhau qhov siab tshaj plaws tau noj txhua hnub ntawm vildagliptin ntawm ib puas milligrams.
Yog tus neeg mob raug mob los ntawm mob raum mus rau mob hnyav, ces Galvus yuav tsum tau siv qhov ncauj ib hnub ib zaug, muab cov tshuaj txhua hnub ntawm tsib caug milligrams.
rau cov neeg laus,nrog rau cov neeg uas raug kev txom nyem los ntawm lub raum tsis ua hauj lwm tsawg kawg nkaus, xws li kev hloov hauv kev noj tshuaj tsis tas yuav tsum tau. Qhov no tau ua pov thawj los ntawm ntau qhov kev tshuaj xyuas ntawm cov neeg mob txaus siab uas muaj tshaj xya caum. Galvus, zoo li tsis muaj lwm yam tshuaj, tau dhau los rau lawv cov tshuaj tiv thaiv kab mob ntshav qab zib.
Puas muaj kev phiv tshwm sim thaum kho nrog vildagliptin? Yog, thiab koj tuaj yeem nyeem txog nws hauv qab no.
Cov tsos mob tsis xis nyob
Feem ntau, cov teebmeem tsis xav tau yog luv luv thiab tej zaum yuav mob me. Nyob rau hauv rooj plaub no, nws tsis yog yuav tsum tau tshem tawm kev siv "Galvus". Txawm li cas los xij, nws tseem tsim nyog qhia koj tus kws kho mob txog qhov tshwm sim tsis zoo.
Kuv yuav tsum xyuam xim rau dab tsi thaum siv vildagliptin?
Ua ntej tshaj, saib koj lub paj hlwb. Koj puas muaj mob taub hau paroxysmal? Puas yog kiv taub hau, tshee hnyo hauv nqua, nervousness feem ntau pom? Yog tias cov tsos mob hnyav dua, kev kho mob yuav tsum tau kho sai sai.
Nrog rau kev noj "Galvus" daim tawv nqaij pob khaus thiab khaus? Koj puas mob khaub thuas lossis kub taub hau? Lub plab hais li cas? Puas yog cem quav ntau zaus? Koj puas tau xeev siab, ntuav, raws plab? Yog tias muaj, tus kws kho mob endocrinologist yuav daws qhov teeb meem no.
Koj yuav tsum tau saib xyuas koj qhov hnyav. Puas muaj qhov nce ntxiv hauv lub cev hnyav tiv thaiv keeb kwm yav dhau los ntawm kev noj zaub mov noj thiab kho gymnastics? Feem ntau, kev siv cov tshuaj ua ke nrog thiazolidinedione ua rau tsis muaj qhov hnyav nce hauvneeg mob. Hauv qhov no, yuav tsum tau tshuaj xyuas cov kev kho mob tau sau tseg.
Yuav ua li cas tus overdose manifests nws tus kheej
Kev kho mob ua pov thawj tias vildagliptin ib txwm txais los ntawm lub cev, txawm tias siv ob puas milligrams ib hnub. Thiab tseem, kev noj ntau dhau ntawm cov khoom tseem ceeb tuaj yeem ua rau muaj kev cuam tshuam tsis zoo thiab cuam tshuam. Ua ntej ntawm tag nrho cov, qhov no yog hais txog ob npaug ntawm cov koob tshuaj hais saum toj no. Nyob rau hauv cov ntaub ntawv no, tej zaum yuav mob heev nqaij, ua npaws, o. Yog tias qhov koob tshuaj txhua hnub tau nce mus rau rau puas milligrams, qhov xwm txheej zoo li no yuav ua rau mob hnyav thiab paresthesia ntawm sab sauv thiab sab qis thiab lwm yam cuam tshuam loj hauv kev ua haujlwm ntawm tag nrho cov kab mob.
Kev kho mob hauv qhov xwm txheej no yuav yog hemodialysis hauv tsev kho mob.
Vildagliptin thiab lwm yam tshuaj siv tshuaj
Raws li tau hais los saum toj no, kev siv "Galvus" nrog cov tshuaj raws li metformin, insulin, sulfonylurea thiab lwm yam. Ntxiv mus, cov tshuaj tuaj yeem ua ke dawb nrog kev siv digoxin, ramipril, valsartan, simvastatin, thiab lwm yam.
Cov nyhuv ntawm vildagliptin txo qis los ntawm cov tshuaj uas nws cov khoom xyaw nquag yog cov thyroid hormones, sympathomimetics, glucocorticosteroids thiab lwm yam.
Yuav khaws tshuaj li cas
Qhov teeb meem no kuj yuav tsum tau muab kev saib xyuas tshwj xeeb, vim tias kev cia cov tshuaj raug cuam tshuam rau nws cov txiaj ntsig. Txuag cov ntsiav tshuaj yuav tsum nyob rau hauv qhov chaw tsaus, nkag tsis tau rau cov menyuam yaus thiab tsiaj txhu, ntawm qhov kub tsis tshaj peb caug degrees. Lub neej txee - 36 lub hlis.
Tus nqi tshuaj
Tau kawg, ntau tus neeg mob ntshav qab zib xav tau cov lus nug, "Galvus" tus nqi yog dab tsi? Tus nqi ntawm ntim cov tshuaj nyob rau hauv 28 ntsiav tshuaj txawv ntawm 750 thiab 850 rubles. Nws tag nrho yog nyob ntawm tus xa khoom thiab chaw tsim khoom.
Thaum yuav cov tshuaj, koj yuav tsum paub tias nws tau muab tso rau hauv cov khw muag tshuaj nruj me ntsis raws li daim ntawv tshuaj.
Tshuaj hloov Galvus
Raws li tau hais los saum no, cov tshuaj yuav tsis haum rau tus neeg mob. Yuav ua li cas rau qhov no? Tus kws kho mob puas yuav muab tshuaj hloov? Yog li, dab tsi txhais tau tias peb tuaj yeem xav txog analogues ntawm "Galvus"? Cov lus qhia rau kev siv cov tshuaj no yuav tham hauv qab no.
Yog tias peb tham txog qhov spectrum ntawm kev ua, ces qhov kev hloov zoo rau vildagliptin yog Byetta txhaj. Cov khoom xyaw nquag ntawm cov tshuaj yog exenatide (250 micrograms hauv ib milliliter). Cov lus qhia rau kev siv tshuaj yog hom 2 mob ntshav qab zib mellitus. "Byteta" yog sau raws li kev txhaj tshuaj subcutaneous nyob rau hauv tus ncej puab, xub pwg, plab. Siv tsib micrograms ntawm cov khoom xyaw nquag ob zaug hauv ib hnub, rau caum feeb ua ntej noj mov thaum sawv ntxov thiab yav tsaus ntuj. Nws yog siv raws li kev kho mob monotherapy thiab ua ke (sib xyaw) kev kho mob nrog metformin, thiazolidinedione thiab lwm yam. Tus nqi ntawm cov tshuaj hauv rau caum koob tuaj yeem tshaj tsib txhiab rubles.
Januvia yog lwm qhov sib piv ntawm Galvus, tsim nyob rau hauv daim ntawv ntawm cov ntsiav tshuaj, cov khoom tseem ceeb ntawm uas yog sitagliptin phosphate hydrate. Cov tshuaj no yog siv los kho mob ntshav qab zib hom 2hom kev kho mob monotherapy thiab complex therapy. Qhov pom zoo kom noj cov tshuaj yog ib puas milligrams ntawm lub ntsiab tivthaiv ib hnub twg. Cov ntsiav tshuaj muaj nrog ntau npaum li cas ntawm cov tshuaj nquag. Tus nqi nruab nrab ntawm ib pob ntawm 28 ntsiav tshuaj yog 1,500 rubles.
"Ongliza" yog lwm cov tshuaj ntsiav tshuaj, uas yog ib qho analogue ntawm cov tshuaj uas peb xav tau. Cov tshuaj "Ongliza" muaj xws li saxagliptin, uas yog cov khoom xyaw nquag. Feem ntau, cov tshuaj yog muab rau hauv qhov ncauj ntawm tsib milligrams (ib ntsiav tshuaj) ib hnub ib zaug. Koj tuaj yeem noj cov tshuaj tsis hais noj mov. Tus nqi ntawm ib pob ntawm peb caug ntsiav tshuaj nce mus txog 1,900 rubles lossis ntau dua.
Txawm li cas los xij, feem ntau, cov kws kho mob endocrinologist hloov Galvus nrog nws cov analogue ncaj qha - Galvus Met ntsiav tshuaj, cov khoom tseem ceeb ntawm cov tshuaj vildagliptin (nyob rau hauv tus nqi ntawm tsib caug milligrams) thiab metformin (nyob rau hauv tus nqi ntawm 500, 850 lossis 1,000 milligrams.). Ua tsaug rau qhov kev sib cuam tshuam no, cov tshuaj tswj cov metabolism hauv thiab txo qis cov roj cholesterol. Nws raug sau tseg los ntawm tus kws kho mob endocrinologist, pib nrog qhov tsawg kawg nkaus (tsib caug milligrams ntawm vildagliptin thiab tsib puas milligrams ntawm metformin). Nws ntseeg tau tias qhov kev kho mob no muaj kev cuam tshuam me me rau lub cev ntawm tus neeg mob uas muaj ntshav qab zib mellitus dua li cov tshuaj txaus siab rau peb. Tus nqi ntawm Galvus Met ntsiav tshuaj yog kwv yees li 1,500 rubles.
Raws li koj tuaj yeem pom, muaj ntau yam analogues ntawm "Galvus", sib txawv ntawm ib leeg hauv kev sib xyaw, daim ntawv tso tawm thiab nqe cai. Qhov twg yog qhov tsim nyog rau koj yog txiav txim siab los ntawm tus kws kho mob tuaj koom, suav nrog tag nrho cov duab ntawm tus kab mob, thiabkuj yog tus yam ntxwv ntawm tus neeg mob.
Ib lo lus kawg
Raws li koj tuaj yeem pom, cov tshuaj "Galvus" yog ib qho pheej yig txhais tau tias tuaj yeem pab tus neeg mob mob ntshav qab zib hom 2. Cov ntsiav tshuaj raws li vildagliptin txhawb lub txiav, muaj txiaj ntsig zoo rau tag nrho lub cev ntawm tus neeg mob. Cov tshuaj tuaj yeem siv los ua kev kho mob ywj pheej, nrog rau kev sib xyaw nrog lwm cov tshuaj.
Txawm hais tias qhov txiaj ntsig zoo, "Galvus" muaj cov npe loj ntawm contraindications thiab kev phiv, yog li koj tsis tuaj yeem sau nws tus kheej. Lub sij hawm nkag thiab ntau npaum li cas yog muab los ntawm tus kws kho mob.
Ntau tus neeg mob zoo siab tias lawv noj cov tshuaj no, vim nws yog ib qho cuab yeej zoo rau kev txo cov ntshav qab zib thiab txhim kho kev noj qab haus huv ntawm tus neeg mob. Thiab tib lub sijhawm, lawv lees paub tias vildagliptin yog qhov zoo tshaj plaws siv nrog metformin txhawm rau txhim kho cov txiaj ntsig thiab kev ua haujlwm ntawm cov tshuaj nquag.
