Gliclazide-raws li cov neeg ua haujlwm yog siv rau kev txhawb nqa kev kho mob ntawm hom 2 mob ntshav qab zib mellitus, uas tsim cov tshuaj insulin molecules. Cov tshuaj no yog ib tiam thib ob sulfonylurea derivative.
yam ntxwv dav dav
Cov tshuaj "Glidiab MV 30" yog suav tias yog Lavxias teb sab analogue ntawm Fabkis cov tshuaj "Diabeton MV". Tsim los ntawm Akrikhin Chemical thiab Pharmaceutical Plant nyob rau hauv cheeb tsam Moscow.
Cov tshuaj yog hais txog cov tshuaj hypoglycemic ntawm qhov ncauj hauv daim ntawv ntsiav tshuaj nrog kev hloov kho. Cov xim ntawm lawv cov qauv yog dawb los yog cream, tej zaum yuav muaj marble inclusions. Cov ntsiav tshuaj zoo li cov thooj voos kheej kheej nrog lub chamfer.
Retail ntim yog ib pob. Nws tuaj yeem muaj 30 lossis 60 ntsiav tshuaj ntim rau hauv daim tawv nqaij.
Composition
Tsis zoo li cov tshuaj "Diabeton MV" nrog koob tshuaj 0.060 g ntawm gliclazide, cov tshuaj "Glidiab MV" muaj ob npaug ntawm cov khoom xyaw zoo tib yam.hauv qab no, uas yog 0.030g.
Cov ntsiav tshuaj tsis muaj zog suav nrog hydroxypropyl methylcellulose, aerosil molecules, magnesium stearate, microcrystalline cellulose.
Tseem tseem muaj cov tshuaj "Glidiab" nrog kev tso tawm ib txwm muaj cov tshuaj nquag. Cov koob tshuaj hauv ib ntsiav tshuaj yog 0.08 g ntawm gliclazide.
Nws ua haujlwm li cas
Cov lus qhia rau kev siv txuas nrog Glidiab MB tshuaj piav qhia txog kev ua ntawm gliclazide, uas txhawb nqa cov tshuaj insulin tso tawm hauv β-hlwb nyob hauv cov txiav.
Raws li cov ntsiav tshuaj, cov tshuaj insulin secretory ua haujlwm ntawm cov piam thaj molecules nce, thiab cov ntaub so ntswg ua rau cov tshuaj insulin ntau dua.
Cov leeg nqaij glycogen synthetase, ua ib qho enzyme intracellular, ua haujlwm zoo dua. Muaj qhov txo qis hauv lub sijhawm txij li pib noj mov mus rau qhov tso tawm ntawm cov tshuaj hormones. Insulin secretion yog rov qab los ntawm lub ncov thaum ntxov, uas txawv gliclazide los ntawm lwm cov sulfonylurea precursors, qhov kev txiav txim ntawm qhov tshwm sim ntawm theem ob. Txo cov piam thaj tom qab noj mov.
Microcirculation txhim kho vim kev koom tes thiab adhesion ntawm platelet hlwb, normalization ntawm permeability ntawm phab ntsa vascular, txo cov kev loj hlob ntawm microthrombotic thiab atherosclerotic txheej txheem, restores cov kev cuam tshuam ntawm ntuj dissolution ntawm cov ntshav txhaws. Qhov ua tau ntawm cov lus teb ntawm receptor formations nyob rau hauv cov hlab ntsha rau adrenaline molecules txo.
Cov tshuaj muaj peev xwm ua rau qeeb ntshav qab zib retinopathy ntawm theem tsis loj hlob. Kev kho mob mus sij hawm ntev nrog cov tshuaj no nyob rau hauv cov xwm txheej ntawm kev puas tsuaj rau cov ntshav qab zib cov ntsiab lus ntawm lub raum lub luag haujlwm rau kev pom tuaj yeem txo qis cov protein ntau hauv cov zis.
Cov tshuaj tsis ua rau lub cev hnyav, tab sis ntawm qhov tsis sib xws, nws txo qis vim qhov cuam tshuam rau theem pib ntawm kev tso tawm insulin. Nws tsis provoke nce insulinemia.
Yuav siv li cas
Cov kws kho mob pom zoo kom siv cov tshuaj rau cov ntshav qab zib siab thib ob. Kev kho mob yog ua tiav nrog cov nyhuv tsis txaus los ntawm kev noj zaub mov thiab kev tawm dag zog.
Rau cov tshuaj "Glidiab MB" cov lus qhia muaj feem cuam tshuam rau kev tiv thaiv kev tsis zoo ntawm cov ntshav qab zib mellitus uas muaj cov tsos mob ntawm nephropathy, retinopathy, myocardial infarction thiab stroke.
Yuav siv li cas
Cov tshuaj noj yog xaiv rau txhua tus neeg mob sib cais, suav nrog kev tshwm sim ntawm tus kabmob, cov piam thaj hauv lub plab khoob thiab 120 feeb tom qab noj mov.
Rau cov tshuaj "Glidiab MV" cov lus qhia rau kev siv tau sau ib hnub thawj zaug ntawm 0.03 g, uas yog sib npaug rau ib ntsiav tshuaj. Qhov concentration yog qhia rau cov neeg laus tom qab 65 xyoo. Cov tshuaj yog siv qhov ncauj, ib ntsiav tshuaj thaum sawv ntxov, thaum noj tshais.
Yog tias tsim nyog, koob tshuaj tau nce txhua ob lub lis piam. Qhov siab tshaj plaws ntawm ib hnub tau tso cai noj txog 0.120 g, uas sib haum rau 4 ntsiav tshuaj.
Tshuaj "Glidiab MV" yog siv los hloov cov tshuaj tso tawm ntawm tib lub npe, siv 1-4 ntsiav tshuaj ib hnub.
Nws tau ua ke nrog tus neeg sawv cev hypoglycemic raws li biguanide, ib qho alpha-glucosidase inhibitor ntawm insulin molecules.
Thaum lub raum tsis ua haujlwm ntawm qhov mob me lossis nruab nrab, thaum tus nqi ntawm creatinine tawm tsis ntau tshaj 0.080 litres ib feeb, qhov ntau npaum li cas tsis txo.
Thaum tsis tau
ntsiav tshuaj "Glidiab MV" cov lus qhia rau kev siv tsis pom zoo kom siv thawj hom kab mob ntshav qab zib mellitus, nrog rau kev nce hauv ketones hauv cov zis, nrog rau plab paresis, nrog hyperosmolar, ntshav qab zib coma thiab precoma, nrog kev phais loj. Kev ua haujlwm thiab hlawv qhov txhab, cov txheej txheem raug mob thaum xav tau kev kho mob insulin.
Kev ua haujlwm tsis zoo ntawm lub siab lossis lub raum ua haujlwm, lub plab zom mov, kev hloov pauv hauv kev zom zaub mov, kev loj hlob ntawm lub xeev hypoglycemic yog contraindicated.
Tsis txhob siv cov tshuaj ua npaws, leukopenia, cev xeeb tub, pub niam mis thiab kev tsis haum rau cov khoom xyaw ntawm cov tshuaj.
Kev ceev faj yuav tsum tau ua thaum tswj hwm cov tshuaj, saib xyuas tshwj xeeb thiab xaiv ntau npaum li cas rau cov neeg mob uas haus dej cawv thiab cov thyroid mob.
Txoj kev kho mob
Rau cov tshuaj "Glidiab MV" cov lus qhia rau kev siv qhia qhov xav tau los ua ke nrog cov khoom noj uas muaj calorie tsawg, suav nrog cov carbohydrates tsawg.cov ntsiab lus. Kev saib xyuas tsis tu ncua ntawm cov piam thaj hauv cov hlab ntshav yuav tsum tau ua thaum sawv ntxov ua ntej thiab tom qab noj mov.
Yog tias muaj kev cuam tshuam kev phais lossis kev txo qis ntawm tus mob ntshav qab zib, nws muaj peev xwm ua kom paub cov tshuaj insulin.
Muaj lus ceeb toom txog qhov tshwm sim ntawm cov txheej txheem hypoglycemic nrog kev siv ethyl cawv, tshuaj tsis-steroidal los tiv thaiv kev mob thiab tsis muaj zaub mov noj. Kev haus cawv tuaj yeem ua rau muaj tus mob zoo li disulfiram, nrog mob taub hau thiab mob plab, thiab xeev siab thiab ntuav.
Cov tshuaj yuav tsum tau hloov kho thaum lub cev lossis lub siab xav thiab noj zaub mov tsis raws sijhawm. Cov neeg laus, cov neeg mob noj zaub mov tsis zoo lossis tsis zoo, cov neeg mob hnyav uas raug kev txom nyem los ntawm adrenal insufficiency, tshwj xeeb tshaj yog rhiab heev. rau kev cuam tshuam ntawm kev kho mob pituitary system.
Thaum thawj theem ntawm kev siv tshuaj thaum xaiv ntau npaum, yog tias muaj qhov ua rau muaj kev kub ntxhov, koj tsis tas yuav ua cov yeeb yam uas yuav tsum tau ua kom muaj kev mloog ntau ntxiv thiab cov tshuaj tiv thaiv psychomotor ceev.
kev tawm tsam tsis zoo
Rau qhov kev kho "Glidiab MV" cov lus qhia suav nrog cov ntaub ntawv hais txog kev ua txhaum cai ntawm cov kab mob endocrine nyob rau hauv rooj plaub ntawm kev ua tsis tiav ntawm kev noj tshuaj thiab hauv cov xwm txheej tsis zoo. Feem ntau, qhov txo qis ntawm cov piam thaj hauv cov hlab ntsha ua rau mob taub hau, nkees, tshaib plab, tsis muaj zog, ntxhov siab vim, tsis muaj zog, aggression, tsis muaj zog.concentration, kev nyuaj siab. Kuj tseem muaj kev hloov pauv hauv kev pom kev pom, kev tshee, kev hnov lus thiab convulsive tsis meej, kiv taub hau, hypersomnia, ua tsis taus pa, qis plawv dhia.
Cov plab hnyuv siab raum tsis ua haujlwm nyob rau hauv daim ntawv ntawm malabsorption, xeev siab, raws plab, anorexic tsis qab los noj mov, ua haujlwm tsis zoo ntawm daim siab, cholestatic jaundice, nce kev ua haujlwm ntawm transaminase enzymes.
Cov txheej txheem tsis xav tau hauv cov kab ke hematopoietic yog cuam tshuam nrog kev txo qis hauv hemoglobin, cov platelet thiab leukocyte cells.
Cov tshuaj tuaj yeem ua rau muaj kev tsis haum tshuaj nyob rau hauv daim ntawv ntawm khaus, urticaria, maculo-papular rhiab.
Kev txhaj tshuaj ntau
Cov lus qhia rau kev siv txuas nrog "Glidiab MV" cov khoom ceeb toom tawm tsam kev siv tshuaj ntau dhau, uas tau qhia los ntawm kev txo qis hauv cov piam thaj hauv cov ntshav plasma. Nrog rau qhov muaj zog ntau dhau ntawm cov tshuaj, qhov hypoglycemic coma tuaj yeem tshwm sim.
Txhawm rau tshem tawm nws, ib tus neeg raug muab los noj qee cov carbohydrates zoo, piv txwv li, lub khob qab zib. Thaum tus neeg tsis nco qab lawm, 40% dextrose lossis qabzib tov yog txhaj rau hauv cov hlab ntsha, thiab glucagon tau txhaj rau hauv cov leeg ntawm qhov ntau ntawm 1 mg. Yog tias tus neeg mob sawv los, ces nws raug yuam kom noj cov carbohydrates zoo kom tsis txhob rov tshwm sim ntawm hypoglycemic nres.
Kev sib xyaw nrog tshuaj
Kev ua haujlwm hypoglycemic ntawm cov tshuaj "Glidiab MB 30 mg" tuaj yeem txhim kho los ntawm kev tswj hwm tib lub sijhawmangiotensin-hloov thiab monoamine oxidase-type enzyme inhibitor, blocker ntawm beta-adrenergic thiab H2-histamine-dependent receptor formations raws li cimetidine, tshuaj tua kab mob miconazole thiab fluconazole, non-steroidal anti-inflammatory tshuaj phenylbutazone, indomethacin, diclofenacin.
Cov txiaj ntsig ntawm cov tshuaj ntsiav yog nce ntxiv nrog kev pab ntawm clofibrates thiab bezafibrates, tshuaj tiv thaiv kab mob los ntawm pawg ethionamide, salicylates, indirect anticoagulant compounds ntawm coumarin qauv, anabolic steroids, cyclophosphamides, chloramphenicols, sulfonamides nrog. muaj txiaj ntsig ntev.
Cov tshuaj txo cov ntshav qab zib kom zoo dua thaum siv tubular tso tawm blockers, ethyl cawv, acarbose, biguanide, insulin.
Kev txo qis hauv cov nyhuv hypoglycemic ntawm cov ntsiav tshuaj yog tshwm sim los ntawm barbiturates, tshuaj raws li epinephrine, clonidine, terbutaline, ritodrine, salbutamol, phenytoin, carbonic anhydrase enzyme inhibitors xws li acetazolamide, thiazide diuretics, thyroid hormones, lithium-muaj. tshuaj, tshuaj estrogen.
Ethyl cawv molecules tuaj yeem ua rau gliclazide nrog qhov tshwm sim ntawm cov txheej txheem disulfiram.
Cov tshuaj nquag ntawm cov ntsiav tshuaj ua rau tsis muaj sijhawm depolarization thiab kev cog lus ntawm ventricles ntawm cov leeg myocardial thaum ua ke nrog plawv glycosides.
Beta-blockers, clonidine, reserpine, guanethidine tshuaj npog qhov ncauj qhov ncauj qhov ntswg hypoglycemia.
Kev xavcov neeg mob
Qhov tseem ceeb tsis yog cov lus qhia rau kev siv txuas nrog cov tshuaj "Glidiab MV". Kev tshuaj xyuas qhia txog qhov tseeb ntawm cov neeg mob xav txog qhov ua tau zoo ntawm cov tshuaj. Cov cuab yeej no pab ntau tus neeg mob kom txo qis cov piam thaj kom zoo li qub, thiab ua ke nrog kev noj haus hloov pauv tus neeg mob txoj kev ua neej.
Tib neeg nco ntsoov tias qhov zoo ntawm cov ntsiav tshuaj yog lawv qhov yooj yim siv thaum sawv ntxov. Thaum nruab hnub, koj tsis nco qab xav tau kev kho mob.
Kev tshuaj xyuas kuj tuaj yeem hnov ntawm cov tshuaj "Glidiab MV" ntawm qhov tsis zoo, cuam tshuam nrog kev ua tsis tau zoo ntawm cov tshuaj no. Qhov no feem ntau tshwm sim thaum noj tshuaj tsis raug, thaum muab tshuaj me me.
