Qee yam mob yuav muaj qee qhov kev tiv thaiv tshuaj, piv txwv li tsis teb rau kev tswj hwm tshuaj. Hauv cov xwm txheej zoo li no, raws li txoj cai, siv cov glucocorticoids. Ib qho ntawm cov tshuaj no yog Metipred. Cov tshuaj no qhia rau dab tsi thiab yog dab tsi?
tshuaj no yog dab tsi?
"Metipred" belongs rau pab pawg neeg hluavtaws glucocorticosteroids, uas yog, nws yog ib qho kev sib xyaw ua ke ntawm cov tshuaj hormones. Nws muaj cov tshuaj tiv thaiv kab mob, muaj kev tiv thaiv kev ua xua, txo qhov o, txo qis kev ua haujlwm ntawm lub cev tiv thaiv kab mob, thiab kho cov kab mob metabolic.
Lub tshuab ntawm nws qhov kev ua haujlwm yog nyob ntawm cov tshuaj tiv thaiv nrog cov receptors tshwj xeeb nyob hauv ntau cov ntaub so ntswg. Vim muaj kev sib txuas nrog lawv, cov proteins tshwj xeeb raug tsim los ua lub luag haujlwm rau kev tswj hwm cov txheej txheem tseem ceeb tshaj plaws.
Cov tshuaj cuam tshuam rau txhua yam txheej txheem metabolic hauv lub cev.
Txij li cov tshuaj belongs rau cov pab pawg ntawm glucocorticosteroids, nws tsuas yog sau rau qee kis thaumCov kev kho mob yooj yim qhia rau kev kho tus kab mob no ua tsis tau zoo.
Metipred siv tau li cas? Vim li cas thiaj muab tshuaj rau tus kab mob no?
Cov lus qhia rau cov tshuaj
Cov kab mob dab tsi yuav tsum tau teem caij tshuaj hormonal rau lawv kho? Metipred qhia txog kev mob dab tsi? Cov tshuaj no qhia rau dab tsi?
Ua ntej tshaj plaws, kev teem sijhawm ntawm cov tshuaj no yog qhov yuav tsum tau ua rau cov kab mob sib kis ntawm cov ntaub so ntswg. Cov no yog: systemic scleroderma, systemic lupus erythematosus, tag nrho cov vasculitis, dermatomyositis. Hauv cov xwm txheej no, cov tshuaj hormone pab txo cov txheej txheem inflammatory, kho cov metabolism hauv cov ntaub so ntswg.
Metipred kuj tau siv dav hauv rheumatology. Cov lus qhia rau kev siv - mob inflammatory kab mob ntawm cov pob qij txha: mob caj dab ntawm gouty thiab psoriatic etiology, osteoarthritis, bursitis, synovitis, ankylosing spondylitis. Cov txiaj ntsig tseem ceeb ntawm cov tshuaj hauv cov kab mob no yog tshuaj tua kab mob thiab tshuaj tua kab mob.
Koj tuaj yeem siv Metipred rau bronchial hawb pob thiab ntau yam kab mob ua xua.
tshuaj tshuaj
Dab tsi yog siv "Metipred" qhia? Nws yuav tsum nco ntsoov tias thaum muab cov tshuaj no, zoo li lwm yam tshuaj hormones, ib tus yuav tsum coj mus rau hauv tus account lub circadian rhythms ntawm lub cev, nrog rau kev ua haujlwm ntawm adrenal cortex. Cov koob tshuaj rau txhua tus neeg mob raug xaiv ib tus zuj zus.
Cov tshuaj hormones txhua hnub yog qhov zoo tshaj plaws thaum sawv ntxov (feem ntau yog qhia kom haus tag nrho cov koob tshuaj thaum 6 txog 8 teev sawv ntxov, lossis faib ua ob koob - thaum 8 thiab 12 teev sawv ntxov). Cov koob tshuaj zoo sib xws tau pom hauv txhua yam tshuaj hormonal. Metipred tsis muaj qhov zam.
Cov ntsiav tshuaj tau noj ncaj qha nrog lossis tom qab noj mov. Hauv cov menyuam yaus, qhov koob tshuaj yog txiav txim siab raws hnub nyoog thiab lub cev qhov hnyav.
Cov qauv ntawm cov tshuaj yog los ntawm 4 mus rau 50 mg ib hnub twg. Cov koob tshuaj ntau dua (txog li 1 g) yog qhia rau cov neeg mob uas muaj kab mob sib kis ntawm cov kab mob hnyav heev. Kev saib xyuas tshwj xeeb yuav tsum tau them rau kev sau tshuaj ua ntej kev hloov pauv hauv nruab nrog cev rau tus neeg tau txais lossis thaum lub sij hawm ua rau hauv vitro fertilization.
Side effects
Nrog rau kev noj tshuaj kom raug thiab ua raws li txhua tus kws kho mob cov ntawv sau thaum noj nws, cov kev mob tshwm sim yuav luag tsis tshwm sim. Txawm li cas los xij, nws yuav tsum nco ntsoov tias yog tias qhov kev txais tos raug ua txhaum cai, cov xwm txheej loj tuaj yeem tsim. Kev siv cov tshuaj no ua rau dab tsi?
"Metipred" feem ntau muaj kev cuam tshuam tsis zoo rau cov kab mob endocrine. Tej zaum yuav muaj qhov txo qis hauv cov piam thaj, kev loj hlob ntawm Itsenko-Cushing's syndrome, ncua kev sib deev kev loj hlob (thaum muab rau menyuam yaus).
Lub plab zom mov tuaj yeem cuam tshuam rau kev tswj hwm cov tshuaj nrog kev txhim kho xeev siab thiab ntuav, hloov cov quav, pancreatitis, rwj, mus txog los ntshav thiab perforation.plab phab ntsa.
Cov txiaj ntsig ntawm "Metipred" ntawm cov hlab plawv system tshwm sim nws tus kheej nyob rau hauv daim ntawv ntawm arrhythmias, bradycardia, deterioration ntawm lub cev nyob rau hauv lub plawv tsis ua hauj lwm.
Rau ib feem ntawm lub paj hlwb, ib qho kev xav zoo li feem ntau pom, kev loj hlob ntawm psychosis, paranoia, insomnia thiab kiv taub hau.
YContraindications
Thaum twg koj yuav tsum tsis txhob siv cov tshuaj no? "Metipred" tsuas yog siv tau rau lub sijhawm luv luv xwb. Nrog rau kev noj haus ntev dua, cov npe ntawm contraindications nthuav dav.
Ua tib zoo siv cov tshuaj rau cov kab mob ntawm lub plab zom mov xws li mob plab, mob plab, mob plab hnyuv, phais plab hnyuv.
Ntau yam kab mob sib kis kuj tseem suav nrog hauv cov npe ntawm cov txheeb ze contraindications, vim nws tsis paub tias lub cev yuav ua li cas rau kev qhia txog tshuaj hormonal. Lwm qhov xwm txheej txwv tsis pub siv cov tshuaj hormones yog lawv cov tshuaj tiv thaiv kab mob.
Tsis txhob siv tshuaj rau ntshav qab zib, rog.
Cov menyuam yaus thiab cov poj niam cev xeeb tub yog cov qeb uas muaj qhov tsis txaus ntseeg rau kev siv Metipred. Nws tsuas yog sau tau thaum muaj kev hem thawj rau lub neej.
Kev sib tham nrog lwm yam tshuaj
Raws li koj paub, ntau yam tshuaj tuaj yeem txhim kho, ua kom tsis muaj zog lossis cuam tshuam rau lwm yam tshuaj. Metipred teb li cas nrog kev teem caij sib luaglwm yam tshuaj?
Kev siv cov tshuaj no nrog lub siab enzyme inducers ua rau txo qis hauv cov ntsiab lus ntawm cov tshuaj nquag hauv cov ntshav (nws cov metabolism nce ntxiv).
Yog tias koj sau Metipred nrog cov tshuaj diuretics, kev pheej hmoo ntawm kev mob plawv tsis ua haujlwm thiab hypokalemia nce ntau.
Metipred pulse therapy thaum muab tshuaj kho plawv glycosides los ntawm qhov kev txiav txim ntawm qhov loj yuav ua rau muaj kev pheej hmoo ntawm ventricular extrasystole.
Methylprednisolone thiab cov tshuaj tiv thaiv coagulants yuav tsum tsis txhob siv ua ke, vim tias qhov kev kho mob tshwm sim tom kawg.
Kev noj tshuaj nrog cawv thiab tshuaj tsis yog tshuaj steroidal ua rau muaj kev pheej hmoo ntawm kev tsim kab mob plab.
"Metipred" txo cov txiaj ntsig ntawm kev tswj hwm cov tshuaj insulin thiab tshuaj tiv thaiv ntshav siab.
Cov lus qhia rau kev siv
Daim ntawv npaum li cas tuaj yeem "Metipred" muaj nyob? Txhua yam ntawm lawv yog dab tsi? Cia peb saib cov lus nug no.
"Metipred" (cov ntsiav tshuaj) yog tshuaj rau cov kab mob tsis mob hnyav, nrog rau qhov tsis muaj contraindications rau kev tswj qhov ncauj.
Lyophilisate yog ib daim ntawv tshwj xeeb ntawm cov tshuaj, uas yog cov hmoov rau dilution thiab intravenous tswj. Lawv yog siv feem ntau hauv cov kab mob hnyav, nrog rau kev saib xyuas xwm txheej ceev.
Cov txiaj ntsig tau pom zoo kom siv tam sim. Yog tias tsim nyog khaws cia rau qee lub sijhawm, qhov no yuav tsum tau ua ntawm qhov kub ntawm 15 mus rau 20qib. Ntawm tus nqi qis dua, koj tuaj yeem khaws cov kev npaj npaj tsis pub ntau tshaj ib hnub.
Rau kev nyab xeeb ntawm tus neeg mob txoj kev noj qab haus huv, nws raug nquahu kom siv cov tshuaj tiv thaiv kab mob sib luag (kom tiv thaiv cov mucous membrane).
Ua ntej siv cov tshuaj, nco ntsoov nrog koj tus kws kho mob tham txog cov koob tshuaj thiab qhov zaus ntawm kev siv.
"Metipred" hauv kev kho mob ntxiv lawm tshob
Hauv gynecology, xws li hauv lwm qhov chaw ntawm cov tshuaj, Metipred kuj siv. Cov tshuaj no qhia rau dab tsi?
Kev siv tshuaj tseem ceeb yog kev tiv thaiv kab mob hauv vitro fertilization.
IVF yog ib txoj kev, lub ntsiab ntawm uas yog cais lub qe los ntawm ib tug poj niam, fertilize nws nyob rau hauv vitro nrog ib tug txiv neej phev thiab qhia lub resulting zygote mus rau hauv lub tsev menyuam.
"Metipred" hauv IVF yog qhia rau qee qhov kev tiv thaiv kab mob. Nws raug nquahu kom siv nws rau ob peb hnub tom qab hloov cov zygote mus rau hauv lub tsev menyuam kab noj hniav. Qhov no yog ua kom tsis suav nrog qhov muaj peev xwm ntawm kev tsis lees paub los ntawm lub cev ntawm "khoom txawv teb chaws".
Yog tias qhov tshwm sim tau zoo, kev cog cov embryo rau hauv lub tsev menyuam mucosa, tsim cov placenta thiab intrauterine loj hlob ntawm embryo tshwm sim.
"Metipred" rau IVF yog qhia rau txhua tus poj niam. Yog hais tias muaj contraindications rau nws siv, nws yog zoo dua mus tsis kam nyob rau hauv vitro fertilization.
Qee cov kab mob ntawm poj niam cev xeeb tub yuav xav tau kev teem caij ntawm cov tshuaj hormones. "Metipred" hauv gynecology yog siv qee zausrau kev kho mob ntawm leukoplakia thiab qee cov txheej txheem inflammatory.
Kev kho mob kab mob
Nyob rau hauv cov xwm txheej no, raws li txoj cai, mus rau qhov hu ua pulse therapy. Qhov tseem ceeb ntawm txoj kev kho mob no yog raws li nram no: rau lub sij hawm luv luv (feem ntau 1-2 hnub), cov tshuaj ntau ntau yog muab rau tus neeg mob, thiab tom qab ntawd rau ob peb lub lis piam (nyob ntawm qhov hnyav thiab hom. ntawm tus kab mob) - noj tshuaj kho mob.
Piv txwv li, hauv kev kho mob vasculitis, cov txheej txheem no yog raws li hauv qab no: Metipred yog thawj zaug muab tshuaj ntawm ntau txog 1000 mg, tom qab ntawd tus neeg mob tau hloov mus rau kev kho mob (80-100 mg).
Cov tswv yim no tau txais kev muaj koob meej vim nws ua haujlwm siab.
Kev qhia txog koob tshuaj loj ua rau "kev ntxhov siab" ntawm tus kab mob thiab kev loj hlob ntawm qhov hu ua metabolic tsis ua haujlwm. Nyob rau tib lub sijhawm, nws yooj yim dua rau cov kab mob cuam tshuam los kho cov kev cuam tshuam ib txwm tsis muaj qhov cuam tshuam zoo li no. Tsis tas li ntawd, vim yog koob tshuaj loj, feem ntau cov kab mob tiv thaiv kab mob tuaj yeem cuam tshuam.
Pulse therapy tuaj yeem ntxiv nrog cytostatics kom ua tiav cov tshuaj tiv thaiv kab mob ntau dua.
Qhov tseem ceeb ntawm kev siv tshuaj
Cov tshuaj no tsis tuaj yeem yuav ntawm lub tsev muag tshuaj xwb. Tsuas yog tus kws kho mob tuaj koom tuaj yeem muab tshuaj rau Metipred. Cov lus qhia rau kev siv yuav tsum muaj zog (piv txwv li, kab mob inflammatory kab mob). Tsuas yog qhov no, tus kws muag tshuaj yuav muab tau cov tshuaj uas koj xav tau.
Lwm yam ntawm kev kho yog qhov ntawdNrog rau kev siv ntev, kev quav tshuaj lossis cov tsos mob tshem tawm tuaj yeem tshwm sim.
Nws txhim kho thaum "Metipred" raug tshuaj rau lub sijhawm ntev thiab koob tshuaj loj. Nyob rau hauv parallel, inhibition ntawm nws tus kheej cov tshuaj hormones tsim nyob rau hauv lub qog adrenal. Hauv qhov no, koj yuav tsum tsis txhob tso tseg cov tshuaj tam sim ntawd. Nws raug nquahu kom maj mam txo cov koob tshuaj rau lub sijhawm ntev. Tsuas yog nyob rau hauv cov xwm txheej zoo li no tuaj yeem rov ua cov tshuaj hormones synthesis.
