Kev pw tsis tsaug zog ntev, kev mob ntawm lub paj hlwb tsis ua rau lawv tus kheej tuag, tab sis lawv ua rau muaj kev phom sij loj rau kev noj qab haus huv thiab kev noj qab haus huv. Cov tshuaj ntawm cov chav kawm barbiturate pab kho cov mob no.
Composition and properties
Barbital sodium yog cov hmoov dawb crystalline hmoov, tsis muaj ntxhiab, nrog qab qab qab. Cov tshuaj formula ntawm cov tshuaj - C8H11N2Na03, belongs rau chav kawm ntawm barbiturates. Synonyms - veronal-sodium, barbitone, medinal. Nws yog soluble nyob rau hauv dej twb nyob rau hauv ib tug ratio ntawm 1 mus rau 5, me ntsis soluble nyob rau hauv cawv. Cov tshuaj aqueous muab cov tshuaj tiv thaiv alkaline; thaum txhaj tshuaj, nws tau npaj siv cov dej tsis muaj tshuaj nyob rau hauv cov xwm txheej tsis muaj menyuam. Yog khaws cia ntev, cov tshuaj decomposes.
High solubility ua rau nws yooj yim rau nqus los ntawm txoj hnyuv, toxicity nyob rau hauv cov nqi pom zoo tsis muaj teeb meem rau kev noj qab haus huv. Nyob ntawm cov koob tshuaj, nws muaj sedative lossis hypnotic nyhuv. Yooj yim tshem tawm ntawm lub cev.
Siv, ntau npaum li cas
Hauv tshuaj, sodium barbital pab nrog insomnia, tsheeoverexcitation, neuralgia, muab anticonvulsant thiab antiemetic nyhuv. Noj tshuaj 30-40 feeb ua ntej yuav mus pw, haus mis nyuj, tshuaj yej sov.
Cov koob tshuaj qhov ncauj pom zoo rau cov neeg laus yog 0.3-0.75 g, rau cov menyuam yaus 0.025 txog 0.25. Qhov siab tshaj plaws noj txhua hnub yog txwv rau 1 thiab 0.5 grams, raws li.
Subcutaneously los yog intramuscularly, cov tshuaj yog muab mus txog 5 mg ntawm ib 10% tov, ntxiv novocaine. Nkag mus rau hauv lub qhov quav yog ua tiav siv enemas (txog 0.5 g ib 5-10 ml dej) los yog suppositories.
Powder yog daim ntawv tseem ceeb ntawm kev tso tawm barbital-sodium, pharmacopoeia txwv tsis pub nws tso tawm hauv cov ntsiav tshuaj. Kev khaws cia ntawm txhais tau tias yog nqa tawm hauv cov ntim kaw ntom ntom vim tias muaj hygroscopicity siab. Kev cais tawm ntawm kev nkag mus rau cov tshuaj rau cov menyuam yaus yog qhov tsim nyog.
Cov tshuaj pom zoo rau ntuav, ntuav, lom tsis yog tib neeg nkaus xwb, tab sis kuj ntawm tsiaj. Barbital sodium nyob rau hauv cov kws kho tsiaj cov tshuaj tsis yog ib qho yooj yim rau kev pw tsaug zog, overexcitation ntawm tsiaj nyeg, dev, miv.
Negative factor
Kev siv cov tshuaj ua rau tsaug zog ntev txog 8 teev, tab sis kev siv dav thiab ruaj khov yog txwv. Qhov tshwj xeeb ntawm cov nyhuv ntawm cov tshuaj tsaug zog yog tias lub sijhawm ntawm lub sijhawm "ceev" nce, theem "slow", ntawm qhov tsis sib xws, vim li ntawd, cov qauv ntawm kev pw tsaug zog cuam tshuam.
Kev siv cov sodium barbital ntau tshaj 15 hnub yog kev quav tshuaj, kev kho mob rau ntau tshaj 1.5 lub hlis yog kev vam khom tshuaj.
Cov kev phiv tshwm sim:
- ntua;
- kev nyuaj siab;
- mob taub hau;
- ua xua
- failure.
Cov tsos mob ntawm cov tsos mob saum toj no yuav tsum tsum tso tseg kev siv tshuaj. Kev hloov ntawm daim tawv nqaij, cov menyuam kawm ntawv dilated, chim siab thiab ntxhov siab vim yog vim li cas thiaj hloov kho.
YContraindications
Muaj ntau yam uas txwv tsis pub siv barbiturates:
- tus neeg tsis kam lees;
- kab mob siab, raum;
- kev ua pa tsis zoo;
- xeeb tub;
- mob ntshav qab zib mellitus;
- yuav tsum haus cawv.
Kev siv sijhawm ntev lossis siv ntau dhau ua rau khaus khaus, aggressiveness, kev xav cuam tshuam thiab txo kev ua haujlwm. Hauv qhov tshwj xeeb, muaj qhov tsis pom kev tsis pom kev, kev hais lus retardation.
Kev Tsim Kho Kev Txhaum Cai
pw tsis tsaug zog, kev sib txawv ntawm lub paj hlwb tuaj yeem kho nrog sodium barbital rau ob lub lis piam. Tom qab ntawd, kev quav yeeb quav tshuaj tshwm sim, ua tiav cov txiaj ntsig zoo yuav tsum tau txhaj tshuaj ntxiv.
Qhov cuam tshuam tsis zoo yog qhov sib ntxiv, tom qab 2-3 lub hlis ntawm kev siv tshuaj dependence tshwm sim. Thaum ntxov, tus neeg mob yuav tsis kam noj tshuaj ntawm nws tus kheej, nrog rau kev tsim txom ntev, kev kho mob hnyav thiab ntev yuav tsum tau ua.
Sodium barbital, zoo li cov tshuaj feem ntau, xav tau kev qhia kho mob thiab kev qhuab qhia tus kheej, tom qab ntawd cov txiaj ntsig zoo yuav ua tiav yam tsis muaj kev cuam tshuam kev noj qab haus huv.
