Progesterone yog cov tshuaj hormones poj niam txiv neej cuam tshuam rau gestagens. Lawv yog tsim nyob rau hauv lub zes qe menyuam los ntawm cov ntaub so ntswg ntawm lub corpus luteum, uas yog tsim raws li ib tug tshwm sim ntawm kev tso tawm ntawm ib tug paub tab qe. Cov tshuaj no txhawb kev tsim cov tshuaj hormonal nyob rau theem ob ntawm lub voj voog, npaj ib tug poj niam kom muaj kev xeeb tub, thiab tseem txhawb nqa cov txheej txheem gestation thaum thawj peb lub hlis twg. Lub ntsiab analogue ntawm Progesterone yog Levonorgestrel.
Nws tau txais hauv cov tshuaj feem ntau yog hluavtaws. Cov tshuaj no yog tsim nyob rau hauv daim ntawv ntawm 1-2.5% roj-raws li tshuaj, uas yog muab intramuscularly.
Lub hauv paus feem ntau yog cov roj refined los ntawm txiv duaj lossis txiv ntseej. Cov tshuaj yog tsim nyob rau hauv ampoules nrog lub peev xwm ntawm 1 ml, thiab tau ntim rau hauv cov thawv ntawv tuab. Rau kev siv qhov ncauj, nws yog yuav hauv cov tshuaj ntsiav, thiab tshem tawm cov cim qhia ntawm mastopathy, mastodynia, daim ntawv gel raug pom zoo rau kev siv sab nraud.
YProgesterone analogues
Muaj ntau cov tshuaj hormonal npaj rau hauv khw muag tshuaj. Muaj ntau ntau analogues hluavtaws ntawm Progesterone. Cov feem ntau siv yog teev hauv qab no.
Injesta
Cov tshuaj yog muab tshuaj intramuscularly lossis subcutaneously. Nrog rau qhov tsis ua haujlwm ntawm lub tsev menyuam los ntshav, tus neeg sawv cev tau muab 1 milliliter ntawm 1% tshuaj txhua hnub rau 6-8 hnub. Yog tias lub tsev menyuam tau ntxuav ua ntej, kev txhaj tshuaj pib tom qab 18-20 hnub. Nyob rau hauv qhov kev tshwm sim uas nws yog unrealistic mus nqa tawm curettage, "Injesta" yog siv txawm lub sij hawm los ntshav. Thaum siv "Injesta" thaum lub sij hawm los ntshav, nws qhov kev ncua sij hawm (hnub thib 3) tuaj yeem saib xyuas, thiab yog li ntawd, cov neeg mob ntshav qab zib tsis txaus thiab mob hnyav tau raug pom zoo kom muab cov ntshav ua ntej (200 lossis 250 milliliters).. Nrog kev tso ntshav tawm, nws tsis tas yuav tsum tso tseg kev kho ua ntej 6 hnub. Yog tias cov ntshav tsis tau nres tom qab 6-8 hnub ntawm kev kho mob, cov lus qhia tom ntej ntawm "Injesta" tsis muaj qab hau.
Cov kev mob tshwm sim los ntawm kev noj cov tshuaj hormone no muaj ntau txoj hauv kev zoo ib yam li cov tsos mob ntawm tus poj niam premenstrual syndrome. Kev noj tshuaj tuaj yeem ua rau mob taub hau, qaug zog, ua rau muaj kev noj qab nyob zoo thiab tsaug zog, nrog rau qhov tshwm sim ntawm ntuav, kev loj hlob ntawm kev nyuaj siab.
Vim qhov koob tshuaj ntxiv, tus poj niam yuav muaj ntshav thiab txo qis kev sib deev. Cov kua tsib tsis yooj yim los ntawm kev noj cov tshuaj progesterone ntev ntev ua rau muaj qhov tshwm sim ntawm cholecystitis thiab tsim cov pob zeb.
Lub peev xwm ntawm gestagens khaws cov kua tuaj yeem ua rau muaj qhov o, nce ntxivsiab, nrog rau cov ntshav txhaws thiab ntshav txhaws.
Lutein
"Lutein" suav nrog cov tshuaj nquag uas tsim tawm hauv zes qe menyuam thiab yog ib feem ntawm pawg gestagens. Cov tshuaj no pab ua kom cov txheej txheem catabolic nyob rau hauv lub cev, qhov tseeb, nws pib synthesis ntawm ntau yam tshuaj, pab tsim cov hlwb tshiab ntawm cov kab mob hauv lub cev.
Tom qab cov progestogen nkag mus rau hauv lub cell nucleus, DNA tau qhib, thiab nws kuj txhim kho RNA synthesis, thaum tib lub sij hawm stimulating synthesis ntawm cov protein, uas plays lub luag hauj lwm ntawm lub tsev cov khoom thoob plaws hauv lub cev. Progesterone, cuam tshuam rau lub tsev menyuam endometrium, muab sijhawm rau nws txav mus los ntawm lub sijhawm proliferation mus rau theem secretion. Lub mucosa nyob rau hauv cov kab mob ntawm cov me nyuam, nyob rau hauv lub cuam tshuam ntawm progesterone, tab tom npaj rau ntxiv fertilization thiab implantation ntawm lub embryo.
Gestagen
Yog tias muaj ntau ntau ntawm cov tshuaj no nyob rau hauv poj niam lub cev thaum cev xeeb tub, tsim ntau cov tshuaj hormones hauv pituitary caj pas uas tswj kev loj hlob thiab tsim cov follicles tshiab, noj qab nyob zoo yuav raug txo. Progesterone tswj hwm txoj cai tshwj xeeb hauv zes qe menyuam, thaiv kev tsim cov tshuaj estrogens ntxiv rau lub luag haujlwm pib ua poj niam.
Thoob plaws hauv peb lub hlis twg, cev xeeb tub tsuas yog zes qe menyuam progesterone. Nrog rau qhov txo qis hauv nws cov nyiaj ntau, muaj qhov nce hauv lub suab ntawm lub tsev menyuam thiab muaj kev hem thawjcuam tshuam.
Muaj nws cov txiaj ntsig ntawm tus poj niam lub mis, progesterone npaj cov kua mis, npaj lub cev xeeb tub rau lactation. Influencing cov metabolism, qhov yuav tsum tau muaj cov rog yog nyob rau hauv cov ntaub so ntswg ntawm tes, thiab cov khoom ntawm carbohydrates tsim nyog nce nyob rau hauv daim siab.
"Gestagen" yog ib qho analogue ntawm "Progesterone", nws ua rau cov tshuaj hormones ntau ntxiv los ntawm cov qog adrenal, tso cai rau koj khaws cov kua dej. Thiab qhov no hauv qee kis tuaj yeem ua rau o thiab nce qhov hnyav ua ntej pib ua poj niam.
"Progestogen" yog txhaj rau hauv cov leeg ntawm 5 mg rau li ib lub lim tiam ntawm lub voj voog tsim tawm.
Krinon
"Progesterone" thiab cov tshuaj analogues hauv cov ntsiav tshuaj yog siv rau hauv cov xwm txheej uas tus poj niam muaj cov tshuaj hormones tsis txaus, nrog rau qee yam kab mob ntawm cov poj niam cev xeeb tub, uas yog nrog los ntawm kev nce ntxiv ntawm cov tshuaj hormones follicular uas tsim tawm. los ntawm zes qe menyuam thaum thawj theem ntawm kev coj khaub ncaws.
Tus kws kho mob tuaj yeem sau ntawv siv cov khoom siv hluavtaws lossis tshuaj ntsuab ntawm "Progesterone" tom qab kev teem sijhawm ntawm cov tshuaj estrogen, uas tuaj yeem muab tshuaj los ntawm cov kws kho mob hauv thawj theem ntawm kev coj khaub ncaws. Cov koob tshuaj "Krinon" yog 10 txhiab units, chav kawm kav 15-20 hnub.
Prognorm
Nrog algomenorrhea, cov tshuaj no tau muab tshuaj ntawm 5-10 mg rau lub lim tiam tom ntej ua ntej pib kev coj khaub ncaws. Ntawmuterine los ntshav dysfunctional, cov tshuaj yog muab rau cov kev cai thiab kev sib raug zoo ntawm lub cev ntas.
Cov tshuaj hormone progesterone tsis tso cai rau lub endometrium kom loj hlob ntau dhau, tswj nws txoj kev hloov nrawm mus rau theem zais cia. Kev noj tshuaj ntawm 5-15 mg ntawm cov tshuaj hormones li ib lub lis piam tom qab qhov kawg ntawm kev coj khaub ncaws yuav tiv thaiv kev loj hlob ntawm lub tsev menyuam los ntshav.
Prolutex
Vim hais tias progesterone siv los ntawm tib neeg lub siab hlwb, kev qhia txog cov tshuaj hormones rau hauv lub cev nrog kev ua haujlwm tsis zoo tsis raug pom zoo vim tias muaj feem ntau ntawm kev noj ntau dhau.
Nws paub tias "Prolutex" yuav tsis muaj txiaj ntsig zoo rau cov ntshav coagulation, txwv tsis pub siv rau cov neeg mob uas muaj kev mob aneurysms thiab varicose leeg. Nrog kev ceev faj heev, cov tshuaj no yuav tsum tau siv rau kev kub siab thiab IRR, nrog rau kev nce siab ntau dhau. Tsis tas li ntawd, progesterone tsis haum rau cov neeg mob uas muaj mob hawb pob bronchial, qaug dab peg, vim tias cov kua dej tuav tau tuaj yeem ua rau lub hlwb o, nrog rau cov mob migraines nquag.
Endometrin
Yog tias tus poj niam tsis tsim cov tshuaj progesterone, tab sis nws yuav tsum ua siab ntev thiab yug tus menyuam noj qab nyob zoo, cov tshuaj tuaj yeem muab tshuaj intravaginally nyob rau hauv daim ntawv ntawm gel, nrog rau cov tshuaj ntsiav sab hauv, 2 daim rau 13-14 hnub, thiab nyob rau hauv lub sij hawm ntawm 15-25 hnub - 1 tsiav tshuaj. Yog tias cev xeeb tub tsis tshwm sim yav tom ntej, txij hnub 26th, koob tshuaj yuav nce ntxivib lub lim tiam rau 1 tsiav tshuaj, tom qab ib pliag mus txog 6 tsiav tshuaj. Ntawd yog, chav kho mob yog 60 hnub.
Utrozhestan
Txhawm rau tshem tawm kev muaj menyuam tsis taus uas tshwm sim vim kev ua haujlwm ntawm zes qe menyuam thiab luteal theem tsis txaus, progesterone raug muab tshuaj los tsim ib theem ib txwm ntawm lub voj voog. Qhov koob tshuaj ntawm cov tshuaj yog 12.5 mg, thiab nws yog siv rau lub sij hawm 14-28 hnub ntawm kev coj khaub ncaws. Thaum cev xeeb tub, kev siv tshuaj txuas ntxiv mus txog thawj 3 lub hlis.
Thaum nchuav menyuam pib, "Progesterone" thiab cov tshuaj analogue, "Utrozhestan", tshwj xeeb, tau muab tshuaj rau hauv ib koob ntawm 10-25 mg, kom txog thaum qhov kev hem thawj ploj mus. Progesterone yuav tsum tau noj ntawm ib koob ntawm 100 mg.
Raws li kev hloov kho nrog qhov pib ntawm lub cev tsis muaj zog, cov tshuaj no tau muab rau hauv tus nqi ntawm 2 capsules rau 10-12 hnub ua ntej pib kev coj khaub ncaws.
A contraindication rau kev siv "Progesterone", nrog rau nws cov analogue "Utrozhestan" yog hu ua kev tsis haum rau cov khoom ntawm cov tshuaj. Cov tshuaj no yog contraindicated rau cov poj niam uas muaj cov kab mob oncological uas twb muaj lawm ntawm lub mis thiab cov plab hnyuv siab raum, vim lawv muaj malignant cell division, metastasis, thiab ceev cov qog loj hlob.
Nyob rau hauv lub thib ob thiab peb lub hlis twg, kev siv ntxiv ntawm progestogens yog contraindicated, vim hais tias nyob rau hauv lub sij hawm no lub placenta tswj kev tsim cov tshuaj hormones.
Kev tshuaj xyuas ntawm kws kho mob
Raws li kws kho mob, "Progesterone" thiab nws cov analogues tau yooj yim coj los ua kev txhaj tshuaj, tshwj xeeb tshaj yog cov tshuaj txij nkawm nyob rau theem ob ntawm lub voj voog, thaum siv cov tshuaj hauv lwm hom (cov tshuaj lossis tshuaj suppositories) tsis muaj qhov tsim nyog ua tau zoo hauv kev tshem tawm kev xeeb tub.
Qhov tsis zoo ntawm cov tshuaj no yog feem ntau ib qho infiltrate tsim nyob rau hauv poj niam lub cev, tshwj xeeb tshaj yog nyob rau ntawm qhov chaw txhaj tshuaj. Undoubtedly, qhov no yuav txwv qee lub sijhawm ntawm kev kho mob.
Cov lus pov thawj tus neeg mob
Cov poj niam, tom qab noj cov tshuaj no, nco ntsoov qhov kev rov qab los ntawm kev coj khaub ncaws, qhov pib thaum ntxov ntawm cev xeeb tub, tshem tawm kev hem thawj ntawm kev rho menyuam, placenta previa, thiab tshem tawm cov suab nrov. Tab sis lawv kuj nco ntsoov qee qhov mob ntawm kev txhaj tshuaj. Cov tshuaj, vim nws qhov ntom ntom ntau thiab oily qauv, yog nqus tau ntev.
Result
"Progesterone" yog ib yam tshuaj zoo heev uas pab tus poj niam kho nws txoj kev sib deev, txo kev muaj menyuam, pab yug menyuam, thiab nce cov tshuaj hormones hauv lub cev. Tej zaum tag nrho cov kev zoo no tau ua "Progesterone" cov tshuaj feem ntau siv hauv gynecology niaj hnub no! Qhov no kuj piav qhia txog qhov muaj ntau ntawm cov analogues ntawm cov tshuaj no.
