Leej twg yog clostridia? Cov no yog cov kab mob uas tsim cov spores uas tsim thaum tsis muaj oxygen. Lawv noj cov organic teeb meem tuag. Ib qho nthuav feature yog tias lawv muaj peev xwm tig cov tshuaj inorganic rau hauv cov organic. Hauv kab lus no, peb yuav tsom mus rau cov kab mob Clostridium perfringens. Xav txog nws cov yam ntxwv nyob rau hauv lub moj khaum ntawm microbiology, kab mob uas nws ua, cov tsos mob ntawm qhov txhab, txoj kev kuaj mob thiab kho.
Leej twg yog clostridia?
Clostridia perfringens yog ib tus neeg sawv cev ntawm Clostridial microorganisms. Lawv qhov chaw nyob tseem ceeb yog dej thiab av. Ntau cov kab mob no yog cov kab mob rau tib neeg - lawv ua rau botulism, gas gangrene, tetanus, ntau hom kab mob colitis.
Yog cov kab mob nkag mus rau hauv cov xwm txheej tsis zoo rau nws tus kheej, nws yuav hloov mus ua tus kab mob. Hauv daim ntawv no, nws tswj kom muaj sia nyob nrog cov pa oxygen hauv huab cua, thiab hauv plua plav, ntawm qhov chaw ntawm cov khoom, ntawm cov tsiaj muaj sia.
Kev nkag mus ntawm clostridium txaus ntshai rau tib neeg lub cev li cas? Kab mobtuaj yeem rhuav tshem nws cov ntaub so ntswg, uas tuaj yeem ua rau muaj qhov tshwm sim loj thiab txawm tuag. Tsis tas li ntawd, ntau tus kws tshawb fawb ntseeg tias nws yog clostridia uas muaj qee yam cuam tshuam rau tib neeg lub siab. Muaj kev xav tias cov kab mob no ua rau muaj kev loj hlob ntawm autism. Hauv kev tiv thaiv ntawm qhov kev xav no, nws tau hais tias kev kho lub cev los ntawm Clostridium ua rau ploj mus ntawm cov tsos mob ntawm kev puas hlwb.
Tus nto moo tshaj plaws clostridia hauv microbiology:
- Clostridium perfringens yog tus ua kom muaj kab mob ntawm cov zaub mov lom (tshwj xeeb yog raws plab).
- Clostridium difficile - pib nquag txhim kho hauv plab hnyuv thaum muaj teeb meem nrog nws cov microflora (tshwj xeeb tshaj yog thaum noj tshuaj tua kab mob), feem ntau nws yuav ib txwm muaj los ntawm ib feem me me hauv tib neeg quav.
mus rau lub ntsiab lus tom ntej.
Clostridia pom hauv cov quav - puas txaus ntshai?
Raws li peb tau hais lawm, Clostridium difficile tuaj yeem pom hauv cov quav ntawm tus neeg noj qab haus huv. Qhov no tau pom nyob rau hauv 3% ntawm cov neeg noj qab haus huv kiag li, hauv 15-20% ntawm cov neeg mob hauv tsev kho mob, chaw kho mob.
Txawm li cas los xij, tus lej ntawm clostridia muaj tseem ceeb ntawm no. Nws yuav tsum tsis txhob tshaj qhov ntsuas - 105 cfu / g. Txhim kho kev tsim tawm, kev loj hlob ntawm clostridia ua rau muaj teeb meem nrog cov hnyuv microflora. Rau tib neeg, qhov no yog qhov txaus ntshai vim hais tias, nyob rau hauv nws lub neej, Clostridium difficile pib tsim cov tshuaj muaj zog uas ua rau muaj kev phom sij rau tus tswv lub cev. Qhov tshwm sim yog raws plab thiab kab mob hnyav dua, pathologies.
Tsis txhob ntshaiQhov tshwm sim yog tias qhov kev faib ua feem ntawm clostridium nyob rau hauv cov txiaj ntsig ntawm kev tsom xam cov quav pom nyob rau hauv qhov qub, thiab koj tsis kuaj koj tus kheej nrog cov tsos mob txaus ntshai - mob plab, ntuav, xeev siab, raws plab. Qhov tseem ceeb tshaj plaws rau koj yog saib xyuas lub xeev noj qab haus huv ntawm koj txoj hnyuv microflora.
Clostridium perfringens - yog dab tsi?
Tus neeg sawv cev ua rau Clostridium perfringens yog lwm hom Clostridium. Nws kuj yog tus cwj pwm los ntawm kev txhim kho cov tshuaj lom muaj zog txaus ntshai rau tib neeg lub cev. Remarkably, cov tshuaj tiv thaiv nws cov khoom txawm tias thaum tshav kub mus rau 100 ° C.
Vim li cas Clostridium perfringens txaus ntshai rau peb? Kev cuam tshuam rau lawv cov co toxins ntawm tib neeg lub cev tuaj yeem ua rau muaj kev phom sij rau cov zaub mov hnyav, mob plab, gastroenteritis.
Zoo li cov hom yav dhau los, Clostridium perfringens feem ntau yuav nyob hauv cov hnyuv ntawm 1/3 ntawm cov neeg noj qab haus huv. Cov kws kho mob microbiologists suav tias nws yog cov kab mob pathogenic microflora, cov kab mob huv huv.
Bacteria Facts
Cia peb saib ze dua ntawm Clostridium perfringens:
- Tus kab mob no tau tshawb pom ntev dhau los - xyoo 1892.
- Raws li gram-zoo (raws li Gram nws muaj xim xiav-violet muaj zog).
- Spore-forming anaerobic kab mob, zoo li lwm hom Clostridium.
- Clostridium perfringens tau txais nws lub npe los ntawm lo lus "spindle". Qhov no yog vim lub peculiarity ntawm tsim ntawm nws spores. Cov kab mob pib o nyob rau hauv qhov chaw, tsim ib tug zoo li me ntsis reminiscent ntawm ib tug microscope.spindle.
- Nyob rau hauv lub xeev ntawm spores, txawm boiling yog zoo zam. Tsis zoo rau kev puas tsuaj ntawm cov tshuaj tua kab mob.
- Cov kab mob Clostridium perfringens tau muab faib ua 6 serotypes. Lub hauv paus rau gradation yog cov cuab yeej antigenic ntawm cov co toxins uas lawv tsim. Yog li ntawd, ntau hom Clostridium perfringens raug xaiv los ntawm Latin cim los ntawm A txog F.
- Txhua hom kab mob muaj nws tus kheej cov kab mob pathogenic - necrotic, enterotoxic, hemotoxic, neurotoxic, thiab lwm yam.
- Cov kab mob A thiab C yog qhov txaus ntshai tshaj plaws rau tib neeg lub cev, thawj hom cuam tshuam rau lub plab zom mov, thiab qhov thib ob tuaj yeem ua rau muaj kev loj hlob ntawm necrotic enteritis.
- Clostridia perfringens yog ib yam kab mob bacillus. Nws qhov ntev yog 4-8 microns. Lub thickness ntawm cov kab mob tsuas yog 0.8-1.5 microns. Nws yog qhov txawv ntawm qhov me me hauv nruab nrab ntawm lub cev.
- YPropagated by spores. Cov xwm txheej zoo tshaj plaws yog qhov chaw uas muaj roj ntau tshwm sim (ib puag ncig anaerobic).
- Ntawm qhov nruab nrab 1g ntawm cov av yuav muaj ntau pua Clostridium perfringens! Lawv kuj tuaj yeem pom muaj ntau hauv txoj kev plua plav, dej phwj tuaj, thiab quav.
- Clostridia perfringens tau pom nyob rau hauv cov tsiaj, hauv tsev thiab qus, hauv tib neeg.
Kev lom neeg ntawm cov kab mob
Clostridium perfringens tiv taus cua sov, kom txias (khaws lawv cov khoom lom neeg txawm tias tom qab nyob hauv lub freezer ntev). Tsis tas li ntawd, lawv tsis quav ntsej txog cov hauv qab noraug:
- ultraviolet;
- xov tooj cua raug;
- cuam tshuam ntawm alkali thiab acid;
- tshuaj tua kab mob, thiab lwm yam.
Spores ntawm cov kab mob, ib zaug ntawm cov khoom noj, germinate yuav luag tam sim. Lawv tuaj yeem kis tau cov nqaij, ntses, khoom noj siv mis, thiab lwm yam. Nws yog qhov txaus ntshai heev rau noj cov zaub mov uas muaj kab mob thaum nws tsis tau txais kev kho cua sov kom zoo. Ib zaug nyob rau hauv cov hnyuv nrog zaub mov, cov kab mob no pib sib ntxiv, ua rau tus neeg muaj co toxins - cov khoom ntawm nws cov haujlwm tseem ceeb.
Kev phom sij ntawm tus kab mob yog dab tsi?
Lub pathogenesis ntawm Clostridium perfringens pib nrog kev ua haujlwm ntawm plab hnyuv nqus ntawm cov tshuaj lom no. Hauv particular, necrotoxin, enterotoxin. Feem ntau ntawm tag nrho cov, lawv yog detrimental rau capillaries ntawm lub mucous daim nyias nyias ntawm cov hnyuv. Ib zaug nyob rau hauv tib neeg cov ntshav, cov tshuaj lom ntawm Clostridium perfringens muaj tshuaj lom thiab necrotic nyhuv ntawm lub cev.
Yog li, cov khoom pov tseg ntawm cov kab mob tuaj yeem ua rau tuag taus. Sib sib zog nqus necrosis, ntau yam hauv cov ntshav, o, hyperemia tau pom nyob rau hauv cov neeg mob uas tuag los ntawm kev puas tsuaj rau kab mob.
Kab mob tshwm sim los ntawm kab mob
raug rau Clostridium perfringens - kab mob tshwm sim los ntawm cov kab mob:
- Ib pawg kab mob raws plab uas nws cov tsos mob qee zaum txaus ntshai zoo ib yam li cov zaub mov lom.
- Necrotic enteritis.
- Colitispseudomembranous.
Tshwj xeeb tshaj yog txaus ntshai yog qhov swb ntawm lub cev los ntawm cov kab mob serotype F. Nws yog nws uas ua rau necrotic enteritis. Nws cov txiaj ntsig yog qhov necrosis ntawm cov ntaub so ntswg sab hauv ntawm txoj hnyuv. Qhov tshwm sim ntawm qhov tshwm sim tuag ntawm tus kab mob no yog siab heev - 30% ntawm cov neeg mob.
daim duab kho mob, cov tsos mob ntawm qhov txhab
Tus kab mob (Clostridium perfringens yog tus neeg sawv cev ntawm no) pib ua rau nws tus kheej hnov 6-24 teev tom qab noj cov khoom muaj kab mob. Feem ntau, cov hnyuv ntxwm thiab cov khoom noj siv mis ua rau tom kawg.
Tus neeg mob sau ntawv:
- mob plab heev;
- ntua;
- nce hauv lub cev kub txog 38-39 ° C;
- cim kev qaug rau lub cev - lethargy, qaug zog, apathy, tsis qab los noj mov, ntxhov siab vim;
- kev ua haujlwm ntawm lub plab zom mov.
Yog tias tus kab mob no loj tuaj, ntau txoj hauv kev nws yuav zoo li tus kab mob gastroenterocolitis:
- ntuav ntshav ntuav;
- cov quav ua kua dej, uas nws zaus qee zaum nce mus txog 15-20 zaug hauv ib hnub;
- ntshav hauv quav.
Qhov peculiarity ntawm swb ntawm Clostridium perfringens yog tias tus kab mob no sai heev. Nws yog ib txwm ua nrog ib tug ntse deterioration nyob rau hauv kev noj qab nyob zoo - lub cev qhuav dej, tsis muaj zog heev, mob mob nyob rau hauv lub plab, tsam plab, nce qhov loj ntawm tus po thiab daim siab, thiab txo cov ntshav siab. Yog tias tus neeg mob tsis tau txais kev kho mob tsim nyog raws sijhawm, ces qhov tshwm sim tuag tsis raug txiav tawm.
Cov tsos mob ntawm qhov txhab ntawm cov menyuam yaus
Cov menyuam yaus lub cev rau qhov swb ntawm nws Clostridium perfringens tuaj yeem ua raws li qhov no:
- ntuav quav;
- Kab mob plab, mob plab;
- mucus impurities hauv quav.
Cov tsos mob no yuav ploj mus ntawm lawv tus kheej hauv 2-3 hnub. Tom qab 4-5 hnub, raws li txoj cai, tus me nyuam cov quav normalizes. Ua ntej peb ntawm no yuav yog ib daim ntawv me me ntawm clostridium. Txawm li cas los xij, tus me nyuam tsis muaj kev pov hwm tiv thaiv tus kab mob hnyav. Feem ntau, nws tau sau tseg hauv cov neeg mob me uas muaj dysbacteriosis ntev - cov menyuam yaus uas tau noj tshuaj tua kab mob ntev ntev.
Kev puas tsuaj nrog serotype A
Serotype A Clostridium perfringens tuaj yeem nkag mus rau hauv lub cev tsis yog nrog zaub mov rau hauv plab hnyuv, tab sis kuj nyob ntawm qhov txhab. Cov kab mob uas tsis tau txais kev kho mob thawj zaug, thaj chaw necrotic, cov ntaub so ntswg uas tsis tau txais cov ntshav txaus yog qhov muaj kev phom sij tshaj plaws ntawm no.
Qhov tshwm sim yuav yog roj (anaerobic) gangrene. Nws ua rau cov nqaij mos necrosis sai heev, edema, tsim roj, thiab ua rau lub cev hnyav heev.
Kev kuaj mob Clostridiosis
Txawm tias tus kws kho mob tsis yog tshwj xeeb yuav pom tias Clostridium perfringens lesion zoo ib yam li cov tsos mob rau ntau lwm yam kab mob hauv plab thiab kab mob. Yog li ntawd, rau kev kuaj mob ntawm "clostridium" ua ntej ntawm tag nrho cov, yuav tsum muaj kev kuaj xyuas ntawm tus neeg mob cov quav. Lub hom phiaj ntawm qhov kev tshwm sim yog kev tshawb pom ntawm enterotoxin (ib qho tshuaj lom uas zais los ntawm cov kab mob) hauv pawg.
Feem ntau, nyob rau hauv lub moj khaum ntawm kev kuaj mob, cov kev paub zoo ntawm VIEF thiab RIGA tau siv.
Clostridia kho mob
Kev kho mob (clostridium perfringens - tus neeg sawv cev ntawm hom clostridium) tsuas yog kws kho mob tau sau tseg. Nws lub ntsiab kev taw qhia yog tshuaj. Feem ntau, qhov no yog noj tshuaj tua kab mob thiab tshuaj tua kab mob:
- Y "Furazolidone"
- "Tetracycline".
- "Monomycin".
- "Azithromycin".
- "Gentamicin".
- "Metronidazole".
- "Tseporin".
Kev noj, kev tswj hwm nyob ntawm hnub nyoog, tus yam ntxwv ntawm lub cev.
Kev kho mob no yuav ua nrog cov tsos mob thiab kev kho tshuaj lom neeg. Rau kev kho sai ntawm kev tiv thaiv kab mob, cov neeg mob kuj tig mus rau cov tshuaj ib txwm siv - kev siv tshuaj ntsuab infusions.
Kev tiv thaiv ntawm daim ntawv no ntawm clostridiosis yuav ua raws li cov cai ntawm kev nyiam huv ntawm tus kheej, kev huv huv thiab khaws cia cov khoom - thiab peb txhua tus, thiab cov neeg ua haujlwm hauv chaw ua zaub mov, khw muag khoom noj tshwj xeeb. Peb yuav tsum nco ntsoov tias cov menyuam yaus lub cev tsis tshua muaj zog rau Clostridium perfringens. Yog li, kev tswj hwm kev noj zaub mov ntawm cov menyuam yaus yuav tsum nruj tshaj plaws.
